brl 44408 has been researched along with idazoxan in 8 studies
| Studies (brl 44408) | Trials (brl 44408) | Recent Studies (post-2010) (brl 44408) | Studies (idazoxan) | Trials (idazoxan) | Recent Studies (post-2010) (idazoxan) |
|---|---|---|---|---|---|
| 82 | 0 | 16 | 1,499 | 40 | 123 |
| Protein | Taxonomy | brl 44408 (IC50) | idazoxan (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0083 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0195 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0195 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0537 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0195 | |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | 2.884 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0195 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (75.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| García-Sevilla, JA; Sastre, M | 1 |
| Blandizzi, C; Carignani, D; Colucci, R; Crema, F; Del Tacca, M; Lazzeri, G; Natale, G | 1 |
| Callado, LF; García-Sevilla, JA; Grijalba, B; Javier Meana, J; Pazos, A | 1 |
| Audinot, V; Cistarelli, L; Gobert, A; Millan, MJ; Newman-Tancredi, A; Rivet, JM | 1 |
| Callado, LF; Gabilondo, AM; Meana, JJ | 1 |
| Mateo, Y; Meana, JJ | 1 |
| Fernández-Pastor, B; Meana, JJ | 1 |
| Beitz, AJ; Kang, SY; Kim, CY; Lee, HJ; Lee, JH; Park, JH; Roh, DH; Yoon, SY | 1 |
8 other study(ies) available for brl 44408 and idazoxan
| Article | Year |
|---|---|
Alpha 2-adrenoceptor subtypes identified by [3H]RX821002 binding in the human brain: the agonist guanoxabenz does not discriminate different forms of the predominant alpha 2A subtype.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Binding, Competitive; Brain; Dioxanes; Edetic Acid; Female; Guanabenz; Guanylyl Imidodiphosphate; Humans; Idazoxan; Imidazoles; Indoles; Isoindoles; Isoquinolines; Male; Piperazines; Receptors, Adrenergic, alpha; Sodium Chloride; Tritium | 1994 |
Determination on functional basis of presynaptic alpha 2-adrenoceptor subtypes in guinea-pig duodenum.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cholinergic Fibers; Duodenum; Electric Stimulation; Gastrointestinal Motility; Guinea Pigs; Idazoxan; Imidazoles; Indoles; Isoindoles; Isoquinolines; Male; Medetomidine; Muscle Contraction; Nordefrin; Norepinephrine; Oxymetazoline; Piperazines; Prazosin; Receptors, Adrenergic, alpha-2; Synaptic Membranes; Vasoconstrictor Agents; Xylazine; Yohimbine | 1996 |
Alpha 2-adrenoceptor subtypes in the human brain: a pharmacological delineation of [3H]RX-821002 binding to membranes and tissue sections.
Topics: Adrenergic alpha-Antagonists; Adult; Autoradiography; Binding Sites; Binding, Competitive; Brain; Female; Frontal Lobe; Hippocampus; Humans; Idazoxan; Imidazoles; Indoles; Isoindoles; Male; Organ Specificity; Radioligand Assay | 1996 |
Simultaneous quantification of serotonin, dopamine and noradrenaline levels in single frontal cortex dialysates of freely-moving rats reveals a complex pattern of reciprocal auto- and heteroreceptor-mediated control of release.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzopyrans; Dopamine; Dopamine Agonists; Frontal Lobe; Guanabenz; Guinea Pigs; Homeostasis; Idazoxan; Imidazoles; Indoles; Isoindoles; Male; Medetomidine; Models, Neurological; Motor Activity; Norepinephrine; Oxadiazoles; Piperazines; Prazosin; Raclopride; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Serotonin; Salicylamides; Serotonin | 1998 |
Differential modulation of alpha2-adrenoceptor subtypes in rat kidney by chronic desipramine treatment.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Clorgyline; Desipramine; Epinephrine; Idazoxan; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Kidney; Kinetics; Male; Monoamine Oxidase Inhibitors; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2 | 1999 |
Determination of the somatodendritic alpha2-adrenoceptor subtype located in rat locus coeruleus that modulates cortical noradrenaline release in vivo.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Brimonidine Tartrate; Cerebral Cortex; Chromatography, High Pressure Liquid; Clonidine; Dendritic Cells; Drug Interactions; Idazoxan; Imidazoles; Indoles; Isoindoles; Isoquinolines; Locus Coeruleus; Male; Microdialysis; Norepinephrine; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Time Factors | 1999 |
In vivo tonic modulation of the noradrenaline release in the rat cortex by locus coeruleus somatodendritic alpha(2)-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Dendrites; Dose-Response Relationship, Drug; Gyrus Cinguli; Idazoxan; Imidazoles; Indoles; Isoindoles; Isoquinolines; Locus Coeruleus; Male; Microdialysis; Naphthyridines; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Time Factors | 2002 |
Chemical stimulation of the ST36 acupoint reduces both formalin-induced nociceptive behaviors and spinal astrocyte activation via spinal alpha-2 adrenoceptors.
Topics: Acupuncture Points; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Astrocytes; Bee Venoms; Citrates; Formaldehyde; Glial Fibrillary Acidic Protein; Idazoxan; Imidazoles; Injections, Spinal; Isoindoles; Male; Mice; Mice, Inbred ICR; Pain; Pain Management; Pain Measurement; Receptors, Adrenergic, alpha-2; Spinal Cord; Stimulation, Chemical | 2011 |