brl 44408 has been researched along with guanfacine in 3 studies
| Studies (brl 44408) | Trials (brl 44408) | Recent Studies (post-2010) (brl 44408) | Studies (guanfacine) | Trials (guanfacine) | Recent Studies (post-2010) (guanfacine) |
|---|---|---|---|---|---|
| 82 | 0 | 16 | 784 | 180 | 273 |
| Protein | Taxonomy | brl 44408 (IC50) | guanfacine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 1.453 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.134 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.249 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 6.447 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 3.014 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 1.453 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 2.098 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hernádi, I; Kovács, P | 1 |
| Elsworth, JD; Jentsch, JD; Roth, RH; Sanchez, D | 1 |
| Hernádi, I; Tóth, M; Uzsoki, B | 1 |
3 other study(ies) available for brl 44408 and guanfacine
| Article | Year |
|---|---|
Yohimbine acts as a putative in vivo alpha2A/D-antagonist in the rat prefrontal cortex.
Topics: Action Potentials; Adrenergic alpha-2 Receptor Antagonists; Animals; Drug Antagonism; Guanfacine; Imidazoles; Indoles; Iontophoresis; Isoindoles; Male; Prefrontal Cortex; Rats; Rats, Long-Evans; Receptors, Adrenergic, alpha-2; Yohimbine | 2006 |
Clonidine and guanfacine attenuate phencyclidine-induced dopamine overflow in rat prefrontal cortex: mediating influence of the alpha-2A adrenoceptor subtype.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Clonidine; Disease Models, Animal; Dopamine; Guanfacine; Imidazoles; Isoindoles; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Schizophrenia | 2008 |
Novelty response of rats determines the effect of prefrontal alpha-2 adrenoceptor modulation on anxiety.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Anxiety; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Guanfacine; Imidazoles; Individuality; Isoindoles; Male; Maze Learning; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Yohimbine | 2011 |