brl 42359 has been researched along with penciclovir in 7 studies
| Studies (brl 42359) | Trials (brl 42359) | Recent Studies (post-2010) (brl 42359) | Studies (penciclovir) | Trials (penciclovir) | Recent Studies (post-2010) (penciclovir) |
|---|---|---|---|---|---|
| 11 | 1 | 3 | 261 | 21 | 59 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boyd, MR; Harnden, MR; Jarvest, RL; Sutton, D; Vere Hodge, RA | 1 |
| Allen, GD; Brown, TA; Filer, CW; Fowles, SE; Hollis, FJ; Mort, EE; Ramji, JV | 1 |
| Chenery, RJ; Clarke, SE; Harrell, AW | 1 |
| Fairless, AJ; Fowles, S; Georgiou, P; Laroche, J; Pratt, SK; Prince, W; Pue, MA | 1 |
| Chang, K; Choi, WS; Im, GJ; Kim, DK; Kim, KH; Kim, YW; Lee, N | 1 |
| Beedham, C; Brown, JE; Clarke, SE; Jordan, CG; Laljee, H; Rashidi, MR | 1 |
| Contreras, MT; Groth, AD; Kado-Fong, HK; Maggs, DJ; Nguyen, KQ; Thomasy, SM | 1 |
1 trial(s) available for brl 42359 and penciclovir
| Article | Year |
|---|---|
Linear pharmacokinetics of penciclovir following administration of single oral doses of famciclovir 125, 250, 500 and 750 mg to healthy volunteers.
Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Adult; Antiviral Agents; Chromatography, High Pressure Liquid; Famciclovir; Guanine; Half-Life; Humans; Male; Middle Aged; Prodrugs; Single-Blind Method; Spectrophotometry, Ultraviolet | 1994 |
6 other study(ies) available for brl 42359 and penciclovir
| Article | Year |
|---|---|
Prodrugs of the selective antiherpesvirus agent 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine (BRL 39123) with improved gastrointestinal absorption properties.
Topics: 2-Aminopurine; Acyclovir; Adenine; Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Famciclovir; Guanine; Intestinal Absorption; Mice; Prodrugs | 1989 |
Metabolic and pharmacokinetic studies following oral administration of famciclovir to the rat and dog.
Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Biotransformation; Blood Proteins; Chromatography, High Pressure Liquid; Dogs; Famciclovir; Feces; Guanine; Male; Mass Spectrometry; Protein Binding; Rats; Rats, Sprague-Dawley; Species Specificity; Spectrophotometry, Ultraviolet | 1995 |
Role of aldehyde oxidase in the in vitro conversion of famciclovir to penciclovir in human liver.
Topics: 2-Aminopurine; Acyclovir; Aldehyde Oxidase; Aldehyde Oxidoreductases; Allopurinol; Antiviral Agents; Benzaldehydes; Cytosol; Famciclovir; Guanine; Humans; Kinetics; Liver; Oxidation-Reduction; Prodrugs; Vitamin K; Xanthine Oxidase | 1995 |
Synthesis and evaluation of amino acid esters of 6-deoxypenciclovir as potential prodrugs of penciclovir.
Topics: Acyclovir; Animals; Antiviral Agents; Biological Availability; Chromatography, High Pressure Liquid; Esters; Guanine; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred ICR; Models, Chemical; Rats; Spectrophotometry | 1999 |
Aldehyde oxidase-catalysed oxidation of methotrexate in the liver of guinea-pig, rabbit and man.
Topics: Acyclovir; Aldehyde Oxidase; Aldehyde Oxidoreductases; Allopurinol; Animals; Chlorpromazine; Enzyme Inhibitors; Guanine; Guinea Pigs; Humans; Kinetics; Liver; Methotrexate; Oxidation-Reduction; Rabbits; Species Specificity; Stereoisomerism; Substrate Specificity; Vitamin K | 1999 |
In vitro cytotoxicity and antiviral efficacy against feline herpesvirus type 1 of famciclovir and its metabolites.
Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Cats; Cell Line; Dose-Response Relationship, Drug; Famciclovir; Guanine; Herpesviridae; Inhibitory Concentration 50; Viral Plaque Assay | 2014 |