Compounds > brl 42359
Page last updated: 2024-09-03

brl 42359 and brl 42810

brl 42359 has been researched along with brl 42810 in 6 studies

Compound Research Comparison

Studies
(brl 42359)		Trials
(brl 42359)		Recent Studies (post-2010)
(brl 42359)		Studies
(brl 42810)		Trials
(brl 42810)		Recent Studies (post-2010) (brl 42810)
111358193119

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boyd, MR; Harnden, MR; Jarvest, RL; Sutton, D; Vere Hodge, RA1
Allen, GD; Brown, TA; Filer, CW; Fowles, SE; Hollis, FJ; Mort, EE; Ramji, JV1
Chenery, RJ; Clarke, SE; Harrell, AW1
Fairless, AJ; Fowles, S; Georgiou, P; Laroche, J; Pratt, SK; Prince, W; Pue, MA1
Beedham, C; Clarke, SE; Rashidi, MR; Smith, JA1
Contreras, MT; Groth, AD; Kado-Fong, HK; Maggs, DJ; Nguyen, KQ; Thomasy, SM1

Trials

1 trial(s) available for brl 42359 and brl 42810

ArticleYear
Linear pharmacokinetics of penciclovir following administration of single oral doses of famciclovir 125, 250, 500 and 750 mg to healthy volunteers.
    The Journal of antimicrobial chemotherapy, 1994, Volume: 33, Issue:1

    Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Adult; Antiviral Agents; Chromatography, High Pressure Liquid; Famciclovir; Guanine; Half-Life; Humans; Male; Middle Aged; Prodrugs; Single-Blind Method; Spectrophotometry, Ultraviolet

1994

Other Studies

5 other study(ies) available for brl 42359 and brl 42810

ArticleYear
Prodrugs of the selective antiherpesvirus agent 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine (BRL 39123) with improved gastrointestinal absorption properties.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:8

    Topics: 2-Aminopurine; Acyclovir; Adenine; Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Famciclovir; Guanine; Intestinal Absorption; Mice; Prodrugs

1989
Metabolic and pharmacokinetic studies following oral administration of famciclovir to the rat and dog.
    Xenobiotica; the fate of foreign compounds in biological systems, 1995, Volume: 25, Issue:5

    Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Biotransformation; Blood Proteins; Chromatography, High Pressure Liquid; Dogs; Famciclovir; Feces; Guanine; Male; Mass Spectrometry; Protein Binding; Rats; Rats, Sprague-Dawley; Species Specificity; Spectrophotometry, Ultraviolet

1995
Role of aldehyde oxidase in the in vitro conversion of famciclovir to penciclovir in human liver.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:2

    Topics: 2-Aminopurine; Acyclovir; Aldehyde Oxidase; Aldehyde Oxidoreductases; Allopurinol; Antiviral Agents; Benzaldehydes; Cytosol; Famciclovir; Guanine; Humans; Kinetics; Liver; Oxidation-Reduction; Prodrugs; Vitamin K; Xanthine Oxidase

1995
In vitro oxidation of famciclovir and 6-deoxypenciclovir by aldehyde oxidase from human, guinea pig, rabbit, and rat liver.
    Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:7

    Topics: 2-Aminopurine; Acyclovir; Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Antiviral Agents; Biotransformation; Cattle; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Famciclovir; Female; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Liver; Male; Oxidation-Reduction; Rabbits; Rats; Rats, Sprague-Dawley; Species Specificity; Spectrophotometry, Ultraviolet; Xanthine Oxidase

1997
In vitro cytotoxicity and antiviral efficacy against feline herpesvirus type 1 of famciclovir and its metabolites.
    Veterinary ophthalmology, 2014, Volume: 17, Issue:4

    Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Cats; Cell Line; Dose-Response Relationship, Drug; Famciclovir; Guanine; Herpesviridae; Inhibitory Concentration 50; Viral Plaque Assay

2014