brine has been researched along with 2-2-2-trifluorodiazoethane* in 1 studies
1 other study(ies) available for brine and 2-2-2-trifluorodiazoethane
Article | Year |
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Brine-Stabilized 2,2,2-Trifluorodiazoethane and Its Application in the Synthesis of CF3-Substituted Cyclopropane α-Amino Acids.
A facile thermodynamic cyclopropanation of trisubstituted olefinic azlactones with a stock solution of CF3CHN2 in CH3CN is realized. This method shows excellent generality, affording a wide range of trifluoromethyl-substituted cyclopropanes bearing azlactone rings in good to high yields and diastereoselectivities. With the products in hand, the trifluoromethyl-substituted cyclopropane α-amino acids and relative peptide derivatives could be readily obtained. Topics: Amino Acids; Azo Compounds; Cyclopropanes; Hydrocarbons, Fluorinated; Molecular Structure; Salts | 2015 |