brimonidine tartrate has been researched along with colforsin in 61 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (18.03) | 18.7374 |
| 1990's | 39 (63.93) | 18.2507 |
| 2000's | 10 (16.39) | 29.6817 |
| 2010's | 1 (1.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gnegy, ME; Mangels, LA | 1 |
| Bourne, HR; Conklin, BR; Wong, YH | 1 |
| Atkinson, BN; Minneman, KP | 1 |
| Dieudonne, MN; Giudicelli, Y; Pecquery, R | 1 |
| Coupry, I; Downing, S; Duzic, E; Lanier, SM | 1 |
| Duzic, E; Lanier, SM | 1 |
| Ball, SG; Ong, ML; Vaughan, PF | 1 |
| McKenzie, FR; Milligan, G | 1 |
| Osborne, NN | 1 |
| Areso, P; García-Sevilla, JA; Giralt, MT; Guimón, J; Padró, D | 1 |
| Carpéné, C; Galitzky, J; Lafontan, M; Langin, D; Larrouy, D | 1 |
| Alari, L; Axelsson, KL; Persson, ML; Post, C; Uhlén, S; Wikberg, JE | 1 |
| Giudicelli, Y; Leneveu, MC; Pecquery, R | 1 |
| Pratt, BL; Takahashi, JS | 1 |
| Galzin, AM; Langer, SZ; Ramdine, R | 1 |
| Uhlén, S; Wikberg, JE | 2 |
| García-Sáinz, JA; Martínez, OM | 1 |
| Areso, P; García-Sevilla, JA; Giralt, MT; Ulibarri, I | 1 |
| Bylund, DB; Ray-Prenger, C; Turner, JT | 1 |
| Bylund, DB; Jones, SB; Toews, ML; Turner, JT | 1 |
| Duman, RS; Enna, SJ; Nomura, S | 1 |
| Duman, RS; Enna, SJ | 1 |
| Agneter, E; Boehm, S; Drobny, H; Huck, S; Koth, G; Singer, EA | 1 |
| Bouloumie, A; Galitzky, J; Lafontan, M; Langin, D; Remaury, A; Tavernier, G; Valet, P | 1 |
| Hara, M; Inoue, M; Irie, T; Mikami, T; Mikami, Y; Minato, A; Omori, K; Uyama, M; Yasukura, T; Zeng, XT | 1 |
| Berlan, M; Bousquet-Mélou, A; Galitzky, J; Lafontan, M | 1 |
| Regunathan, S; Reis, DJ | 1 |
| Kurose, H; Lefkowitz, RJ | 1 |
| Milligan, G | 1 |
| Malik, KU; Schwartz, DD | 1 |
| Abel, PW; Bockman, CS; Gonzalez-Cabrera, I | 1 |
| Arner, P; Hellström, L; Langin, D; Reynisdottir, S; Rössner, S | 1 |
| Ogihara, M | 1 |
| Itoh, Y; Kimura, K; Oka, M; Shimidzu, T; Ukai, Y; Yoshikuni, Y | 1 |
| Goldstein, I; Huang, YH; Moreland, RB; Traish, AM | 1 |
| Després, JP; Marcotte, M; Mauriège, P; Prud'Homme, D; Tremblay, A; Yoshioka, M | 1 |
| Correze, C; Dib, K; el Jamali, A; Lambert, B; Wrisez, F | 1 |
| Huang, L; Huynh, LP; Mangrum, AJ; Momose-Hotokezaka, A; Okusa, MD | 1 |
| Lu, L; Ordway, GA | 1 |
| Kendall, DA; Roberts, RE; Tomlinson, AE; Wilson, VG | 1 |
| Minneman, KP; Williams, NG; Zhong, H | 1 |
| Soares-da-Silva, P; Vieira-Coelho, MA | 1 |
| Milligan, G; Sautel, M | 1 |
| Albert, PR; Ghahremani, MH; Lembo, PM | 1 |
| Borea, PA; Caiazza, A; Gessi, S; Portaluppi, F; Rastelli, G; Varani, K | 1 |
| Kendall, DA; Roberts, RE; Wilson, VG | 2 |
| Bobirnac, I; Gazi, L; Loetscher, E; Parsley, S; Schoeffter, P | 1 |
| Eikenburg, DC; Shivachar, AC | 1 |
| Kitazawa, T; Maezono, Y; Taneike, T | 1 |
| Després, JP; Imbeault, P; Mauriège, P; Prud'Homme, D; Tremblay, A | 1 |
| García-Barrado, MJ; Iglesias-Osma, MC; Moratinos, J; Sancho, C | 1 |
| Blaylock, NA; Chan, SL; Dunn, WR; Minyan, W; Wilson, VG | 1 |
| Flammer, J; Haefliger, IO; Liu, R | 1 |
| Flammer, J; Haefliger, IO; Liu, R; Wu, R | 1 |
| Eglen, RM; Kendall, DA; Maclennan, SJ; Pinthong, D; Wilson, VG | 1 |
| Haefliger, I; Wu, R; Yao, K; Yin, J | 1 |
| Fraga, S; Jose, PA; Simão, S; Soares-da-Silva, P | 1 |
| Baki, A; Bekes, Z; Boros, A; Bugovics, G; Gere, A; Ignácz-Szendrei, G; Kolok, S; Kurko, D; Nagy, J; Szombathelyi, Z | 1 |
| Bylund, DB; Montgomery, MD | 1 |
2 trial(s) available for brimonidine tartrate and colforsin
| Article | Year |
|---|---|
Platelet alpha2-adrenoceptor alterations in patients with essential hypertension.
Topics: Adrenergic alpha-Antagonists; Blood Platelets; Brimonidine Tartrate; Colforsin; Cyclic AMP; Epinephrine; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hypertension; Male; Middle Aged; Protein Binding; Quinoxalines; Receptors, Adrenergic, alpha-2; Thermodynamics | 1999 |
Adipose tissue metabolism in young and middle-aged men after control for total body fatness.
Topics: Adipose Tissue; Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Agonists; Adult; Aging; Body Composition; Brimonidine Tartrate; Bucladesine; Cell Separation; Colforsin; Epinephrine; Glycerol; Humans; Isoproterenol; Lipolysis; Lipoprotein Lipase; Male; Middle Aged; Quinoxalines; Theophylline | 2000 |
59 other study(ies) available for brimonidine tartrate and colforsin
| Article | Year |
|---|---|
Cyclic AMP accumulation alters calmodulin localization in SK-N-SH human neuroblastoma cells.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Alprostadil; Analgesics; Brimonidine Tartrate; Bucladesine; Calcium; Calmodulin; Carbachol; Cell Line; Colforsin; Cyclic AMP; Cytosol; Edetic Acid; Egtazic Acid; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Kinetics; Neuroblastoma; Quinoxalines; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1992 |
Gz-mediated hormonal inhibition of cyclic AMP accumulation.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Dinoprostone; Dopamine; Gene Expression Regulation; GTP-Binding Proteins; Hormones; In Vitro Techniques; Lysophospholipids; Pertussis Toxin; Quinoxalines; Rats; Signal Transduction; Transfection; Virulence Factors, Bordetella | 1992 |
Preferential desensitization of beta- versus alpha 2-adrenergic receptors accelerates loss of response to norepinephrine in primary glial cultures.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cells, Cultured; Colforsin; Cyclic AMP; Female; Isoproterenol; Neuroglia; Norepinephrine; Pregnancy; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1992 |
Characteristics of the alpha 2/beta-adrenoceptor-coupled adenylate cyclase system and their relationship with adrenergic responsiveness in hamster fat cells from different anatomical sites.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Colforsin; Cricetinae; Dioxanes; Epididymis; Epinephrine; GTP-Binding Proteins; Idazoxan; Isoproterenol; Kinetics; Lipolysis; Macromolecular Substances; Male; Mesocricetus; Organ Specificity; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Skin; Theophylline | 1992 |
Factors determining the specificity of signal transduction by guanine nucleotide-binding protein-coupled receptors. I. Coupling of alpha 2-adrenergic receptor subtypes to distinct G-proteins.
Topics: 3T3 Cells; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cell Membrane; Colforsin; Cyclic AMP; Epinephrine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Mice; Pertussis Toxin; Quinoxalines; Receptors, Adrenergic, alpha; RNA, Messenger; Signal Transduction; Transfection; Virulence Factors, Bordetella; Yohimbine | 1992 |
Factors determining the specificity of signal transduction by guanine nucleotide-binding protein-coupled receptors. III. Coupling of alpha 2-adrenergic receptor subtypes in a cell type-specific manner.
Topics: 3T3 Cells; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Cell Line; Colforsin; Cyclic AMP; Edetic Acid; Egtazic Acid; Epinephrine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Manganese; Mice; Muscle, Smooth; PC12 Cells; Pertussis Toxin; Quinoxalines; Rats; Receptors, Adrenergic, beta; Signal Transduction; Transfection; Virulence Factors, Bordetella | 1992 |
Regulation of noradrenaline release from rat occipital cortex tissue chops by alpha 2-adrenergic agonists.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Brimonidine Tartrate; Bucladesine; Clonidine; Colforsin; Cyclic AMP; Histological Techniques; Male; Norepinephrine; Occipital Lobe; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Cholera toxin impairment of opioid-mediated inhibition of adenylate cyclase in neuroblastoma x glioma hybrid cells is due to a toxin-induced decrease in opioid receptor levels.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Brimonidine Tartrate; Cholera Toxin; Colforsin; Enkephalin, Leucine-2-Alanine; Glioma; GTP Phosphohydrolases; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Hybrid Cells; Immunoblotting; Neuroblastoma; Pertussis Toxin; Quinoxalines; Receptors, Opioid; Receptors, Opioid, delta; Signal Transduction; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1991 |
Inhibition of cAMP production by alpha 2-adrenoceptor stimulation in rabbit retina.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Clonidine; Colforsin; Cyclic AMP; GTP-Binding Proteins; In Vitro Techniques; Pertussis Toxin; Phosphoric Diester Hydrolases; Quinoxalines; Rabbits; Retina; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1991 |
Alpha 2-adrenoceptor-mediated inhibition of platelet adenylate cyclase and induction of aggregation in major depression. Effect of long-term cyclic antidepressant drug treatment.
Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Adult; Aged; Antidepressive Agents, Tricyclic; Blood Platelets; Brimonidine Tartrate; Colforsin; Depressive Disorder; Epinephrine; Female; Humans; Male; Middle Aged; Platelet Aggregation; Quinoxalines; Receptors, Adrenergic, alpha | 1990 |
Non-adrenergic sites for imidazolines are not directly involved in the alpha 2-adrenergic antilipolytic effect of UK 14304 in rat adipocytes.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Brimonidine Tartrate; Bucladesine; Cell Membrane; Colforsin; Dioxanes; Idazoxan; Kinetics; Lipolysis; Phentolamine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1990 |
Antinociceptive actions of alpha 2-adrenoceptor agonists in the rat spinal cord: evidence for antinociceptive alpha 2-adrenoceptor subtypes and dissociation of antinociceptive alpha 2-adrenoceptors from cyclic AMP.
Topics: Adrenergic alpha-Agonists; Animals; Benzylamines; Brimonidine Tartrate; Colforsin; Cyclic AMP; Guanfacine; Male; Neurotoxins; Nociceptors; Pain Measurement; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Spinal Cord; Yohimbine | 1990 |
Influence of androgenic status on the alpha 2/beta-adrenergic control of lipolysis in white fat cells: predominant alpha 2-antilipolytic response in testosterone-treated-castrated hamsters.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Brimonidine Tartrate; Clonidine; Colforsin; Cricetinae; Cyclic AMP; Epinephrine; Isoproterenol; Lipolysis; Male; Mesocricetus; Niacin; Orchiectomy; Phentolamine; Propranolol; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Testosterone | 1988 |
Vasoactive intestinal polypeptide and alpha 2-adrenoceptor agonists regulate adenosine 3',5'-monophosphate accumulation and melatonin release in chick pineal cell cultures.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Agonists; Amino Acid Sequence; Animals; Brimonidine Tartrate; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Kinetics; Melatonin; Molecular Sequence Data; Pineal Gland; Quinoxalines; Radioimmunoassay; Sequence Homology, Nucleic Acid; Structure-Activity Relationship; Vasoactive Intestinal Peptide | 1989 |
Involvement of adenylate cyclase and protein kinase C in the alpha 2-adrenoceptor-mediated inhibition of noradrenaline and 5-hydroxytryptamine release in rat hypothalamic slices.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Antihypertensive Agents; Brimonidine Tartrate; Colforsin; Dioxanes; Electric Stimulation; Hypothalamus; Idazoxan; In Vitro Techniques; Male; Norepinephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin | 1989 |
Alpha 2-adrenoceptors mediate inhibition of cyclic AMP production in the spinal cord after stimulation of cyclic AMP with forskolin but not after stimulation with capsaicin or vasoactive intestinal peptide.
Topics: Adenine; Animals; Brimonidine Tartrate; Capsaicin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Male; Quinoxalines; Receptors, Adrenergic, alpha; Spinal Cord; Tissue Distribution; Vasoactive Intestinal Peptide | 1989 |
Functional alpha 2-adrenoceptors in rat adipocytes: inhibition of cyclic AMP accumulation.
Topics: Adenylate Cyclase Toxin; Adipose Tissue; Animals; Brimonidine Tartrate; Clonidine; Colforsin; Cricetinae; Cyclic AMP; Male; Pertussis Toxin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella | 1989 |
Uncoupling of the platelet alpha 2-adrenoceptor adenylate cyclase system by N-ethylmaleimide and the resulting effect on receptor density and sensitivity.
Topics: Adenylyl Cyclases; Adult; Antihypertensive Agents; Blood Platelets; Brimonidine Tartrate; Colforsin; Ethylmaleimide; Humans; In Vitro Techniques; Kinetics; Male; Quinoxalines; Receptors, Adrenergic, alpha; Sulfhydryl Reagents | 1988 |
Alpha 2-adrenergic receptors in the human cell line, HT29. Characterization with the full agonist radioligand [3H]UK-14,304 and inhibition of adenylate cyclase.
Topics: Adenocarcinoma; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Brimonidine Tartrate; Cell Line; Clonidine; Colforsin; Colonic Neoplasms; Dose-Response Relationship, Drug; Guanosine Triphosphate; Humans; Kinetics; Magnesium; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine | 1985 |
Alpha 2-adrenergic receptor-mediated sensitization of forskolin-stimulated cyclic AMP production.
Topics: Adenine; Adenocarcinoma; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Cell Line; Colforsin; Colonic Neoplasms; Cyclic AMP; Humans; Kinetics; Norepinephrine; Quinoxalines; Receptors, Adrenergic, alpha | 1987 |
In vivo or in vitro exposure to imipramine reduces alpha 2-adrenoceptor-mediated inhibition of cyclic AMP production in rat brain cerebral cortical slices.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cerebral Cortex; Colforsin; Cyclic AMP; Drug Interactions; Imipramine; Male; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1987 |
Inhibition of cyclic AMP production by alpha 2-adrenoceptor stimulation in the guinea-pig spinal cord slices.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Brimonidine Tartrate; Colforsin; Cyclic AMP; Guinea Pigs; In Vitro Techniques; Male; Prazosin; Quinoxalines; Spinal Cord; Yohimbine | 1988 |
A procedure for measuring alpha 2-adrenergic receptor-mediated inhibition of cyclic AMP accumulation in rat brain slices.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain; Brimonidine Tartrate; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Male; Mianserin; Norepinephrine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide | 1986 |
Alpha 2-adrenoceptor-mediated inhibition of electrically evoked [3H]noradrenaline release from chick sympathetic neurons: role of cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Agonists; Adrenergic Fibers; Animals; Brimonidine Tartrate; Calcium Channels; Cells, Cultured; Chick Embryo; Cholera Toxin; Colforsin; Cyclic AMP; Electric Stimulation; Neurons; Norepinephrine; Quinoxalines; Receptors, Adrenergic, alpha-2; Tritium | 1994 |
Molecular mechanisms underlying regional variations of catecholamine-induced lipolysis in rat adipocytes.
Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Base Sequence; Brimonidine Tartrate; Bucladesine; Catecholamines; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Dioxanes; DNA Primers; Epididymis; Gene Expression; Idazoxan; Isoproterenol; Lipase; Lipolysis; Male; Molecular Sequence Data; Organ Specificity; Polymerase Chain Reaction; Propanolamines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; RNA, Messenger; Skin | 1995 |
Adrenergic receptor-mediated Cl- transport in rabbit corneal endothelial cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetates; Acetazolamide; Adrenergic Agonists; Adrenergic Antagonists; Affinity Labels; Animals; Brimonidine Tartrate; Cells, Cultured; Chlorides; Colforsin; Dose-Response Relationship, Drug; Endothelium, Corneal; Fluorescent Dyes; Ion Transport; Isoproterenol; Microscopy, Fluorescence; Norepinephrine; Phentolamine; Phenylephrine; Photometry; Quinolines; Quinoxalines; Rabbits; Receptors, Adrenergic; Yohimbine | 1995 |
Control of lipolysis in intra-abdominal fat cells of nonhuman primates: comparison with humans.
Topics: Abdomen; Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenocorticotropic Hormone; Aged; Animals; Brimonidine Tartrate; Bucladesine; Callithrix; Colforsin; Female; Humans; In Vitro Techniques; Lipolysis; Macaca fascicularis; Male; Middle Aged; Papio; Peptide YY; Peptides; Primates; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Purinergic P1; Species Specificity | 1995 |
Effects of moxonidine, an imidazoline antihypertensive agent, on second messenger systems in rat brain.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Antihypertensive Agents; Brain Chemistry; Brain Stem; Brimonidine Tartrate; Cerebral Cortex; Colforsin; Cyclic AMP; Cyclic GMP; Imidazoles; In Vitro Techniques; Norepinephrine; Phosphatidylinositols; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Second Messenger Systems; Yohimbine | 1994 |
Differential desensitization and phosphorylation of three cloned and transfected alpha 2-adrenergic receptor subtypes.
Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Brimonidine Tartrate; Cell Line; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Kinetics; Molecular Sequence Data; Molecular Weight; Norepinephrine; Phosphates; Phosphorylation; Quinoxalines; Receptors, Adrenergic, alpha-2; Recombinant Proteins; Transfection | 1994 |
Specificity and functional applications of antipeptide antisera which identify G-protein alpha subunits.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Amino Acid Sequence; Animals; Antibody Specificity; Blotting, Western; Brimonidine Tartrate; Cell Line; Cell Membrane; Colforsin; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Erythrocyte Membrane; GTP Phosphohydrolases; GTP-Binding Proteins; Immune Sera; Immunoassay; Indicators and Reagents; Kinetics; Macromolecular Substances; Molecular Sequence Data; Peptides; Quinoxalines; Recombinant Proteins; Turkeys | 1994 |
Cyclic AMP modulates but does not mediate the inhibition of [3H]norepinephrine release by activation of alpha-2 adrenergic receptors in cultured rat ganglion cells.
Topics: Adrenergic alpha-Agonists; Animals; Animals, Newborn; Brimonidine Tartrate; Cells, Cultured; Chromatography, Paper; Colforsin; Cyclic AMP; Electric Stimulation; Ganglia, Sympathetic; In Vitro Techniques; Norepinephrine; Quinoxalines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Thionucleotides | 1993 |
Alpha-2 adrenoceptor subtype causing nitric oxide-mediated vascular relaxation in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Colforsin; Cyclic AMP; Endothelium, Vascular; In Vitro Techniques; Kinetics; Mesenteric Arteries; Nitric Oxide; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Swine; Vasodilation | 1996 |
Regulation of lipolysis in fat cells of obese women during long-term hypocaloric diet.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Adrenergic beta-Agonists; Adult; Brimonidine Tartrate; Bucladesine; Catecholamines; Colforsin; Dobutamine; Energy Intake; Female; Food Deprivation; Glucose; Humans; Insulin; Insulin Resistance; Isoproterenol; Lipolysis; Middle Aged; Obesity; Propanolamines; Quinoxalines; Terbutaline; Time Factors | 1996 |
Cell-density-dependent expression of the alpha(2)-adrenergic response by epidermal growth factor (EGF) in primary cultures of adult rat hepatocytes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cell Count; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Cytochalasin B; Epidermal Growth Factor; Genistein; Isoflavones; Liver; Male; Oxymetazoline; Pertussis Toxin; Protein Biosynthesis; Proteins; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella; Yohimbine | 1996 |
Involvement of metabotropic glutamate receptors in Gi- and Gs-dependent modulation of adenylate cyclase activity induced by a novel cognition enhancer NS-105 in rat brain.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic alpha-Agonists; Alanine; Animals; Baclofen; Brimonidine Tartrate; Cell Membrane; Cerebral Cortex; Cholera Toxin; Cognition; Colforsin; Cyclic AMP; Cycloleucine; Excitatory Amino Acid Antagonists; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Isoproterenol; Kinetics; Male; Manganese; Pertussis Toxin; Piperidines; Proline; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Neurotransmitter; Virulence Factors, Bordetella; Yohimbine | 1997 |
Expression of functional alpha2-adrenergic receptor subtypes in human corpus cavernosum and in cultured trabecular smooth muscle cells.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Binding, Competitive; Brimonidine Tartrate; Cells, Cultured; Colforsin; Cyclic AMP; Humans; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Penis; Quinoxalines; Radioisotopes; Receptors, Adrenergic, alpha-2; Ribonucleases; RNA, Messenger; Yohimbine | 1997 |
Regional differences in adipose tissue metabolism between sedentary and endurance-trained women.
Topics: Abdomen; Adipocytes; Adipose Tissue; Adrenergic alpha-Agonists; Adult; Analysis of Variance; Brimonidine Tartrate; Bucladesine; Cells, Cultured; Colforsin; Epinephrine; Exercise Test; Female; Humans; Life Style; Lipolysis; Lipoprotein Lipase; Oxygen Consumption; Physical Endurance; Physical Fitness; Quinoxalines; Regression Analysis; Respiration; Skin; Thigh | 1997 |
Sodium saccharin inhibits adenylyl cyclase activity in non-taste cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipocytes; Adrenergic alpha-Agonists; Animals; Astrocytes; Brimonidine Tartrate; Carcinogens; Cell Fractionation; Cell Membrane; Cerebral Cortex; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; GTP-Binding Proteins; Idazoxan; Male; Pertussis Toxin; Phenylisopropyladenosine; Quinoxalines; Rats; Rats, Wistar; Saccharin; Signal Transduction; Swine; Taste; Thyroid Gland; Virulence Factors, Bordetella | 1997 |
Regulation of adenylyl cyclase in polarized renal epithelial cells by G protein-coupled receptors.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cell Line; Cell Membrane; Cell Polarity; Colforsin; Cyclic AMP; Epithelial Cells; Gene Expression Regulation; GTP-Binding Proteins; Kidney; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Purinergic P1; Recombinant Proteins; Transfection | 1997 |
Alpha2C-adrenoceptors mediate inhibition of forskolin-stimulated cAMP production in rat striatum.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Colforsin; Corpus Striatum; Cyclic AMP; Functional Laterality; In Vitro Techniques; Kinetics; Male; Oligonucleotides, Antisense; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; RNA, Messenger; Transcription, Genetic | 1997 |
Alpha2-adrenoceptor-mediated contractions of the porcine isolated ear artery: evidence for a cyclic AMP-dependent and a cyclic AMP-independent mechanism.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Agonists; Angiotensin II; Animals; Arteries; Brimonidine Tartrate; Colforsin; Cyclic AMP; Ear; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Nitroprusside; Quinoxalines; Receptors, Adrenergic, alpha-2; Swine | 1998 |
Differential coupling of alpha1-, alpha2-, and beta-adrenergic receptors to mitogen-activated protein kinase pathways and differentiation in transfected PC12 cells.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Colforsin; Enzyme Activation; Inositol Phosphates; Isopropyl Thiogalactoside; JNK Mitogen-Activated Protein Kinases; Kinetics; Mitogen-Activated Protein Kinases; Nerve Growth Factors; Norepinephrine; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Quinoxalines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Recombinant Proteins; Signal Transduction; Transfection | 1998 |
Alpha2-adrenoceptors mediate the effect of dopamine on adult rat jejunal electrolyte transport.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amiloride; Animals; Brimonidine Tartrate; Bucladesine; Cardiotonic Agents; Colforsin; Diuretics; Dopamine; Dose-Response Relationship, Drug; Electric Impedance; Electrolytes; Furosemide; Ion Transport; Jejunum; Male; Ouabain; Phentolamine; Prazosin; Propranolol; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2 | 1998 |
Loss of activation of Gs but not Gi following expression of an alpha2A-adrenoceptor-Gi1alpha fusion protein.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Binding Sites; Brimonidine Tartrate; Cholera Toxin; Colforsin; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Oxymetazoline; Pertussis Toxin; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Virulence Factors, Bordetella | 1998 |
Receptor selectivity of the cloned opossum G protein-coupled receptor kinase 2 (GRK2) in intact opossum kidney cells: role in desensitization of endogenous alpha2C-adrenergic but not serotonin 1B receptors.
Topics: Adrenergic alpha-Agonists; Amino Acid Sequence; Animals; Base Sequence; beta-Adrenergic Receptor Kinases; Blotting, Northern; Brimonidine Tartrate; Cell Line; Cloning, Molecular; Colforsin; Cyclic AMP-Dependent Protein Kinases; G-Protein-Coupled Receptor Kinase 2; Kidney; Molecular Sequence Data; Mutation; Opossums; Quinoxalines; Rats; Receptor, Serotonin, 5-HT1B; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Recombinant Proteins; Sequence Homology, Amino Acid | 1999 |
A study of NPY-mediated contractions of the porcine isolated ear artery.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Angiotensin II; Animals; Brimonidine Tartrate; Colforsin; Cyclic AMP; Ear, External; In Vitro Techniques; Isometric Contraction; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Neuropeptide Y; Nitroprusside; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Neuropeptide Y; Regional Blood Flow; Swine; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Functional alpha2C-adrenoceptors in human neuroblastoma SH-SY5Y cells.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Guanfacine; Humans; Idazoxan; Isoquinolines; Neuroblastoma; Oxymetazoline; Piperazines; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Yohimbine | 1999 |
Differential effects of epinephrine and norepinephrine on cAMP response and g(i3)alpha protein expression in cultured sympathetic neurons.
Topics: Adrenergic Agonists; Animals; Brimonidine Tartrate; Cells, Cultured; Colforsin; Cyclic AMP; Epinephrine; GTP-Binding Protein alpha Subunits, Gi-Go; Isoproterenol; Neurons; Norepinephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Superior Cervical Ganglion | 1999 |
alpha(2)-adrenoceptor and NPY receptor-mediated contractions of porcine isolated blood vessels: evidence for involvement of the vascular endothelium.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic Agonists; Animals; Brimonidine Tartrate; Colforsin; Endothelium, Vascular; Humans; Neuropeptide Y; Quinoxalines; Receptors, Adrenergic, alpha-2; Swine; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 1999 |
The mechanisms of alpha(2)-adrenoceptor agonist-induced contraction in longitudinal muscle of the porcine uterus.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Calcium Channel Blockers; Clonidine; Colforsin; Cyclic AMP; Female; Fluorescent Dyes; Fura-2; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Myometrium; Pertussis Toxin; Quinoxalines; Swine; Uterus; Verapamil; Virulence Factors, Bordetella | 2000 |
Effects of verapamil and elgodipine on isoprenaline-induced metabolic responses in rabbits.
Topics: Adipose Tissue; Animals; Blood Glucose; Brimonidine Tartrate; Calcium Channel Blockers; Colforsin; Consciousness; Dihydropyridines; Dose-Response Relationship, Drug; Epinephrine; Glucose; In Vitro Techniques; Insulin; Islets of Langerhans; Isoproterenol; Male; Metabolism; Potassium; Quinoxalines; Rabbits; Verapamil | 2001 |
Evidence for a non-adrenoceptor, imidazoline-mediated contractile response to oxymetazoline in the porcine isolated rectal artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Agonists; Animals; Arteries; Benzofurans; Brimonidine Tartrate; Colforsin; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Norepinephrine; Oxymetazoline; Phenoxybenzamine; Potassium Chloride; Quinoxalines; Receptors, Adrenergic; Rectum; Swine; Vasoconstriction | 2001 |
Brimonidine and inhibition of nitrite production in isolated porcine ciliary processes.
Topics: Adrenergic alpha-Agonists; Animals; Aqueous Humor; Brimonidine Tartrate; Ciliary Body; Colforsin; Intraocular Pressure; Nitric Oxide; Nitrites; Quinoxalines; Swine | 2001 |
Inhibition by brimonidine of forskolin-induced nitrite production in isolated pig ciliary processes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Ciliary Body; Colforsin; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gi-Go; Nitrites; Pertussis Toxin; Quinoxalines; Receptors, Adrenergic, alpha-2; Swine; Virulence Factors, Bordetella | 2002 |
No evidence for activation of alpha(2)-adrenoceptors by methanolic extracts of bovine brain and lung containing clonidine-displacing substance.
Topics: Adrenergic alpha-Agonists; Animals; Brain Chemistry; Brimonidine Tartrate; Cattle; Clonidine; Colforsin; Cyclic AMP; Guinea Pigs; In Vitro Techniques; Lung; Male; Methanol; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Swine; Tissue Extracts; Vas Deferens; Veins | 2003 |
Inhibition by brimonidine of forskolin-induced nitric oxide synthase expression in human ciliary bodies in vitro.
Topics: Adrenergic alpha-Agonists; Blotting, Western; Brimonidine Tartrate; Ciliary Body; Colforsin; Cryopreservation; Humans; In Vitro Techniques; Nitric Oxide Synthase; Quinoxalines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue and Organ Harvesting | 2007 |
Oxidative stress plays a permissive role in alpha2-adrenoceptor-mediated events in immortalized SHR proximal tubular epithelial cells.
Topics: Acetophenones; Actins; Animals; Brimonidine Tartrate; Bucladesine; Cell Line, Transformed; Chloride-Bicarbonate Antiporters; Colforsin; Epithelial Cells; Hydrogen Peroxide; Kidney Tubules, Proximal; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Pertussis Toxin; Quinoxalines; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha-2 | 2008 |
Comparative pharmacology of adrenergic alpha(2C) receptors coupled to Ca(2+) signaling through different Galpha proteins.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Calcium Signaling; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Fluorometry; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Humans; Quinoxalines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-2; Receptors, G-Protein-Coupled; Recombinant Proteins; RNA, Messenger; Transfection | 2009 |
Lack of effect of the alpha2C-adrenoceptor Del322-325 polymorphism on inhibition of cyclic AMP production in HEK293 cells.
Topics: Adenylyl Cyclases; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Binding, Competitive; Brimonidine Tartrate; Cell Line; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Humans; Linear Models; Norepinephrine; Polymorphism, Genetic; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Signal Transduction; Transfection | 2010 |