brimonidine has been researched along with clonidine in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (38.46) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Butler, RC; Chapleo, CB; England, DC; Myers, PL; Roach, AG; Smith, CF; Stillings, MR; Tulloch, IF | 1 |
| Arendsen, DL; Basha, FZ; Bush, EN; DeBernardis, JF; Kerkman, DJ; Kyncl, JJ; McClellan, WJ; Winn, M | 1 |
| Counsell, RE; Neubig, R; Van Dort, M | 1 |
| Batink, H; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B | 1 |
| de Jonge, A; Lam, E; Slothorst-Grisdijk, FP; Timmermans, PB; van Meel, JC; van Zwieten, PA | 1 |
| Bonhaus, DW; Chang, LK; Chang, TK; Daunt, DA; Eglen, RM; Hsu, SA; Jasper, JR; Lesnick, JD; Yamanishi, SS | 1 |
| Peltonen, JM; Pihlavisto, M; Scheinin, M | 1 |
| Pihlavisto, M; Scheinin, M; Sjöholm, B; Wurster, S | 1 |
| Harms, GS; Lohse, MJ; Steinmeyer, R; Vilardaga, JP | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Callado, LF; Meana, JJ; Ortega, JE; Rodriguez, F; Rozas, I | 1 |
| Callado, LF; Erdozain, AM; Meana, JJ; Ortega, JE; Rodriguez, F; Rozas, I | 2 |
13 other study(ies) available for brimonidine and clonidine
| Article | Year |
|---|---|
Heteroaromatic analogues of the alpha 2-adrenoreceptor partial agonist clonidine.
Topics: Adrenergic alpha-Agonists; Animals; Brain; Clonidine; Heterocyclic Compounds; Male; Rats; Vas Deferens | 1989 |
Conformationally defined adrenergic agents. 1. Design and synthesis of novel alpha 2 selective adrenergic agents: electrostatic repulsion based conformational prototypes.
Topics: Adrenergic alpha-Agonists; Animals; Chemical Phenomena; Chemistry, Physical; Electricity; Male; Molecular Conformation; Motion; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship | 1985 |
Radioiodinated p-iodoclonidine: a high-affinity probe for the alpha 2-adrenergic receptor.
Topics: Affinity Labels; Clonidine; Humans; Iodine Radioisotopes; Receptors, Adrenergic, alpha | 1987 |
Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cell Membrane; Clonidine; Kinetics; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Vasoconstriction | 1984 |
Characterization of alpha-adrenoceptor populations. Quantitative relationships between cardiovascular effects initiated at central and peripheral alpha-adrenoceptors.
Topics: Animals; Blood Pressure; Blood Vessels; Brain; Hemodynamics; Male; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1981 |
Ligand efficacy and potency at recombinant alpha2 adrenergic receptors: agonist-mediated [35S]GTPgammaS binding.
Topics: Adenylyl Cyclases; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cell Line; Cell Membrane; Cyclic AMP; Genetic Vectors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Mice; Protein Binding; Quinolizines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Recombinant Proteins | 1998 |
Subtype-specific stimulation of [35S]GTPgammaS binding by recombinant alpha2-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Adrenergic, alpha-2; Sulfur Radioisotopes | 1998 |
Modulation of agonist binding to recombinant human alpha2-adrenoceptors by sodium ions.
Topics: Adrenergic alpha-Agonists; Allosteric Regulation; Animals; Binding, Competitive; Cations, Monovalent; Guanylyl Imidodiphosphate; Humans; Idazoxan; Mammary Neoplasms, Animal; Mice; Norepinephrine; Receptors, Adrenergic, alpha-2; Recombinant Proteins; Sodium; Tumor Cells, Cultured | 1998 |
Molecular basis of inverse agonism in a G protein-coupled receptor.
Topics: Adrenergic alpha-2 Receptor Agonists; Cell Line; Fluorescence Resonance Energy Transfer; Humans; Ligands; Protein Binding; Receptors, Adrenergic, alpha-2; Receptors, G-Protein-Coupled; Signal Transduction | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Guanidine and 2-aminoimidazoline aromatic derivatives as alpha(2)-adrenoceptor antagonists, 1: toward new antidepressants with heteroatomic linkers.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Binding, Competitive; Blood-Brain Barrier; Brain; Guanidines; Humans; Imidazolines; In Vitro Techniques; Male; Microdialysis; Radioligand Assay; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2007 |
Guanidine and 2-aminoimidazoline aromatic derivatives as alpha2-adrenoceptor antagonists. 2. Exploring alkyl linkers for new antidepressants.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Antidepressive Agents; Blood-Brain Barrier; Brain; Guanidines; Humans; Imidazoles; Imidazolines; In Vitro Techniques; Male; Microdialysis; Radioligand Assay; Rats; Rats, Sprague-Dawley; Stilbenes; Structure-Activity Relationship; Tetrahydronaphthalenes | 2008 |
Guanidine and 2-aminoimidazoline aromatic derivatives as alpha2-adrenoceptor ligands: searching for structure-activity relationships.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Brimonidine Tartrate; Guanidines; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Imidazoles; Microdialysis; Neurons; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship | 2009 |