brij-58 has been researched along with 12-hydroxy-5-8-10-heptadecatrienoic-acid* in 1 studies
1 other study(ies) available for brij-58 and 12-hydroxy-5-8-10-heptadecatrienoic-acid
| Article | Year |
|---|---|
The production of 5-HETE and leukotriene B in rat neutrophils from carrageenan pleural exudates.
Rat neutrophils isolated from three-hour carrageenan pleural exudates actively metabolize arachidonic acid into three major metabolites, HHT, 11-HETE and 15-HETE. However, in the presence of the calcium ionophore, A23187, or the non-ionic detergent, BRIJ 56, these cells also produce 5-HETE and LTB. The production of these lipoxygenase products is calcium dependent. While non-steroidal anti-inflammatory drugs do not affect 5-HETE or LTB production, BW 755C and ETYA inhibit formation of these metabolites from exogenously added arachidonic acid. Topics: Animals; Arachidonic Acids; Calcimycin; Carrageenan; Cetomacrogol; Exudates and Transudates; Fatty Acids, Unsaturated; Hydroxy Acids; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxygenase; Male; Neutrophils; Pleura; Rats | 1981 |