brevianamide-a and asperphenamate

brevianamide-a has been researched along with asperphenamate* in 1 studies

Other Studies

1 other study(ies) available for brevianamide-a and asperphenamate

Article	Year
Petrosifungins A and B, novel cyclodepsipeptides from a sponge-derived strain of Penicillium brevicompactum. Journal of natural products, 2004, Volume: 67, Issue:3 A strain of Penicillium brevicompactum derived from a specimen of the Mediterranean sponge Petrosia ficiformis was investigated for its secondary metabolites. Using fast centrifugal partitioning chromatography (FCPC) two previously unknown cyclodepsipeptides, petrosifungins A (1) and B (2), were isolated, both containing two neighboring units of the nonproteinogenic amino acid l-pipecolinic acid. The absolute configurations of all amino acids were established to be l using GITC derivatization and Marfey's method. Furthermore, the known metabolite brevianamide A (3) was isolated. The likewise known compounds mycophenolic acid (4) and asperphenamate (5) were identified from their spectroscopic properties directly in the extract using HPLC-UV, -MS, and -NMR coupling. Topics: Alkaloids; Animals; Chromatography, High Pressure Liquid; Depsipeptides; Mediterranean Sea; Molecular Structure; Mycophenolic Acid; Nuclear Magnetic Resonance, Biomolecular; Penicillium; Peptides, Cyclic; Phenylalanine; Piperazines; Porifera; Spiro Compounds	2004

Article

Year

Petrosifungins A and B, novel cyclodepsipeptides from a sponge-derived strain of Penicillium brevicompactum.

Journal of natural products, 2004, Volume: 67, Issue:3

A strain of Penicillium brevicompactum derived from a specimen of the Mediterranean sponge Petrosia ficiformis was investigated for its secondary metabolites. Using fast centrifugal partitioning chromatography (FCPC) two previously unknown cyclodepsipeptides, petrosifungins A (1) and B (2), were isolated, both containing two neighboring units of the nonproteinogenic amino acid l-pipecolinic acid. The absolute configurations of all amino acids were established to be l using GITC derivatization and Marfey's method. Furthermore, the known metabolite brevianamide A (3) was isolated. The likewise known compounds mycophenolic acid (4) and asperphenamate (5) were identified from their spectroscopic properties directly in the extract using HPLC-UV, -MS, and -NMR coupling.

Topics: Alkaloids; Animals; Chromatography, High Pressure Liquid; Depsipeptides; Mediterranean Sea; Molecular Structure; Mycophenolic Acid; Nuclear Magnetic Resonance, Biomolecular; Penicillium; Peptides, Cyclic; Phenylalanine; Piperazines; Porifera; Spiro Compounds

2004