bretazenil has been researched along with gamma-aminobutyric acid in 12 studies
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
| Studies (bretazenil) | Trials (bretazenil) | Recent Studies (post-2010) (bretazenil) | Studies (gamma-aminobutyric acid) | Trials (gamma-aminobutyric acid) | Recent Studies (post-2010) (gamma-aminobutyric acid) |
|---|---|---|---|---|---|
| 101 | 8 | 14 | 40,215 | 1,423 | 9,631 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 9 (75.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Facklam, M; Haefely, WE; Schoch, P | 1 |
| Costa, E; Ducic, I; Puia, G; Vicini, S | 1 |
| Bottlaender, M; Brouillet, E; Chavoix, C; Dodd, RH; Fournier, D; Hantraye, P; Khalili-Varasteh, M; Mazière, M | 1 |
| Gallager, DW; Heninger, C; Hernandez, TD; Wilson, MA | 1 |
| Chiu, TH; Li, M; Rosenberg, HC | 1 |
| Drescher, U; Knoflach, F; Malherbe, P; Mohler, H; Scheurer, L | 1 |
| Arban, R; Costa, E; Ducić, I; Giusti, P; Guidotti, A; Puia, G; Walser, A | 1 |
| Benke, D; Benson, JA; Carter, DB; Hamilton, BJ; Knoflach, F; Lüddens, H; Mohler, H; Scheurer, L; Wang, Y | 1 |
| Atack, JR; McKernan, RM; Smith, AJ | 1 |
| Członkowska, A; Nazar, M; Płaźnik, A; Siemiatkowski, M; Sienkiewicz-Jarosz, H | 1 |
| Atack, J; Banks, G; Kelly, MD; Maubach, KA; Seabrook, GR; Smith, A; Whiting, PW; Wingrove, P | 1 |
| Illingworth, E; Kajiwara, K; Kimoto, S; Kishimoto, T; Mugikura, S; Muraki, K; Tanigaki, K; Toritsuka, M | 1 |
12 other study(ies) available for bretazenil and gamma-aminobutyric acid
| Article | Year |
|---|---|
Relationship between benzodiazepine receptor occupancy and potentiation of gamma-aminobutyric acid-stimulated chloride flux in vitro of four ligands of differing intrinsic efficacies.
Topics: Animals; Benzodiazepinones; Cell Membrane; Cerebral Cortex; Chlorides; Diazepam; Drug Synergism; Flumazenil; gamma-Aminobutyric Acid; Ligands; Male; Rats; Receptors, GABA-A; Triazolam | 1992 |
Molecular mechanisms of the partial allosteric modulatory effects of bretazenil at gamma-aminobutyric acid type A receptor.
Topics: Allosteric Regulation; Animals; Animals, Newborn; Benzodiazepinones; Cell Line; Cells, Cultured; Cerebral Cortex; Chloride Channels; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Humans; Ion Channels; Kidney; Membrane Potentials; Membrane Proteins; Neurons; Rats; Receptors, GABA-A; Transfection | 1992 |
In vivo bidirectional modulatory effect of benzodiazepine receptor ligands on GABAergic transmission evaluated by positron emission tomography in non-human primates.
Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Carbolines; Cerebral Cortex; Diazepam; Electroencephalography; Flumazenil; gamma-Aminobutyric Acid; Ligands; Male; Papio; Pentylenetetrazole; Receptors, GABA-A; Seizures; Synaptic Transmission; Tomography, Emission-Computed | 1991 |
Relationship of agonist efficacy to changes in GABA sensitivity and anticonvulsant tolerance following chronic benzodiazepine ligand exposure.
Topics: Animals; Anticonvulsants; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Bicuculline; Brain Chemistry; Diazepam; Drug Tolerance; Electrophysiology; Flumazenil; gamma-Aminobutyric Acid; Male; Raphe Nuclei; Rats; Rats, Inbred Strains; Seizures | 1989 |
Tolerance to the effects of diazepam, clonazepam and bretazenil on GABA-stimulated Cl- influx in flurazepam tolerant rats.
Topics: Animals; Benzodiazepinones; Chloride Channels; Clonazepam; Diazepam; Drug Tolerance; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA | 1993 |
Full and partial agonism displayed by benzodiazepine receptor ligands at recombinant gamma-aminobutyric acidA receptor subtypes.
Topics: Benzodiazepinones; Carbolines; Cells, Cultured; DNA; Drug Synergism; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Imidazoles; Kinetics; Ligands; Macromolecular Substances; Pyrimidines; Receptors, GABA-A; Recombinant Proteins; Sensitivity and Specificity; Substrate Specificity; Transfection | 1993 |
Imidazenil: a new partial positive allosteric modulator of gamma-aminobutyric acid (GABA) action at GABAA receptors.
Topics: Allosteric Regulation; Animals; Benzodiazepines; Benzodiazepinones; Chloride Channels; Conflict, Psychological; Diazepam; Flumazenil; gamma-Aminobutyric Acid; Imidazoles; Male; Membrane Proteins; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reflex; Seizures | 1993 |
Pharmacological modulation of the diazepam-insensitive recombinant gamma-aminobutyric acidA receptors alpha 4 beta 2 gamma 2 and alpha 6 beta 2 gamma 2.
Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Binding Sites; Carbolines; Diazepam; Furosemide; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Imidazoles; Kinetics; Membrane Potentials; Radioligand Assay; Rats; Receptors, GABA-A; Recombinant Proteins; Sensitivity and Specificity; Zinc | 1996 |
Benzodiazepine modulation of recombinant alpha1beta3gamma2 GABA(A) receptor function efficacy determination using the Cytosensor microphysiometer.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Biosensing Techniques; Cell Count; Cells, Cultured; Dose-Response Relationship, Drug; Eukaryotic Cells; Flumazenil; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Humans; Pyridines; Receptors, GABA-A; Recombinant Proteins; Time Factors; Zolpidem | 1998 |
The role of the hippocampus and 5-HT/GABA interaction in the central effects of benzodiazepine receptor ligands.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepinones; Brain; Conflict, Psychological; Dentate Gyrus; Dopamine; Drinking Behavior; Electroshock; Exploratory Behavior; Fenclonine; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Hydroxyindoleacetic Acid; Male; Microinjections; Midazolam; Motor Activity; Norepinephrine; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; Serotonin; Zolpidem | 1999 |
Role of the histidine residue at position 105 in the human alpha 5 containing GABA(A) receptor on the affinity and efficacy of benzodiazepine site ligands.
Topics: Anticonvulsants; Arginine; Azides; Benzodiazepines; Benzodiazepinones; Binding Sites; Binding, Competitive; Cell Line; Cells, Cultured; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Histidine; Humans; Ligands; Mutation; Protein Subunits; Receptors, GABA-A | 2002 |
Selective overexpression of Comt in prefrontal cortex rescues schizophrenia-like phenotypes in a mouse model of 22q11 deletion syndrome.
Topics: Animals; Benzodiazepinones; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; DiGeorge Syndrome; Disease Models, Animal; Dopamine; Dopamine Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Gene Expression; Mice; Mice, Knockout; Prefrontal Cortex; Receptors, N-Methyl-D-Aspartate; Reelin Protein; Reverse Transcriptase Polymerase Chain Reaction; Schizophrenia | 2012 |