bretazenil has been researched along with flumazenil in 26 studies
| Studies (bretazenil) | Trials (bretazenil) | Recent Studies (post-2010) (bretazenil) | Studies (flumazenil) | Trials (flumazenil) | Recent Studies (post-2010) (flumazenil) |
|---|---|---|---|---|---|
| 101 | 8 | 14 | 4,673 | 426 | 981 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.69) | 18.7374 |
| 1990's | 17 (65.38) | 18.2507 |
| 2000's | 5 (19.23) | 29.6817 |
| 2010's | 2 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cook, JM; Dayer, CA; He, X; Huang, Q; Liu, R; Ma, C; McKernan, R; Wenger, GR; Yu, S | 1 |
| Battle, MR; Bouvet, DR; Brown, SL; Ewan, AL; Gaeta, A; Goggi, J; Guilbert, BB; Jackson, A; Jones, CL; Jones, PA; O'Shea, DM; Plant, SD; Trigg, W; Woodcraft, JL; Zheng, PH | 1 |
| Facklam, M; Haefely, WE; Schoch, P | 1 |
| Bonetti, EP; Facklam, M; Haefely, WE; Jenck, F; Martin, JR; Moreau, JL; Schoch, P | 1 |
| Gibert-Rahola, J; Maldonado, R; Micó, JA; Valverde, O | 1 |
| Bottlaender, M; Brouillet, E; Chavoix, C; Dodd, RH; Fournier, D; Hantraye, P; Khalili-Varasteh, M; Mazière, M | 1 |
| Di Scala, G; Rohmer, JG; Sandner, G | 1 |
| Haefely, W | 1 |
| Gallager, DW; Heninger, C; Hernandez, TD; Wilson, MA | 1 |
| Acri, JB; Witkin, JM; Wong, G | 1 |
| Bronson, ME | 1 |
| Barber, DJ; Cooper, SJ | 1 |
| Arban, R; Costa, E; Ducić, I; Giusti, P; Guidotti, A; Puia, G; Walser, A | 1 |
| Hadingham, KL; Palmer, KJ; Thompson, SA; Wafford, KA; Whiting, PJ | 1 |
| Besnard, F; Faure, C; Graham, D; Langer, SZ | 1 |
| Acri, JB; Barrett, JE; Gleeson, S; Witkin, JM | 1 |
| Benke, D; Michel, C; Mohler, H | 1 |
| Macey, DJ; Miczek, KA; Weerts, EM | 1 |
| Atack, JR; McKernan, RM; Smith, AJ | 1 |
| Durant, F; Evrard, G; George, P; López-Romero, B; Sevrin, M | 1 |
| Bergman, J; Paronis, CA | 1 |
| Atack, J; Banks, G; Kelly, MD; Maubach, KA; Seabrook, GR; Smith, A; Whiting, PW; Wingrove, P | 1 |
| Ator, NA; Griffiths, RR; Kaminski, BJ; Weerts, EM | 1 |
| Atack, JR; Cook, SM; McKernan, RM; Pym, LJ; Rosahl, T | 1 |
| Atack, JR; Cook, SM; Guiblin, A; McKernan, RM; Moyes, C; Pike, A; Pym, LJ; Rosahl, TW; Scott-Stevens, P; Sohal, B; Watt, AP | 1 |
| Cook, JM; Groenink, L; Hansen, HH; Mirza, NR; Nielsen, EØ; Olivier, B; van Oorschot, R; Vinkers, CH | 1 |
26 other study(ies) available for bretazenil and flumazenil
| Article | Year |
|---|---|
Pharmacophore/receptor models for GABA(A)/BzR subtypes (alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2) via a comprehensive ligand-mapping approach.
Topics: Animals; Benzodiazepines; Carbolines; Cell Line; Columbidae; Conditioning, Operant; Crystallography, X-Ray; Humans; Indoles; Ligands; Male; Models, Molecular; Pyrimidines; Quinolones; Radioligand Assay; Receptors, GABA-A; Saimiri; Stereoisomerism; Structure-Activity Relationship | 2000 |
The development of potential new fluorine-18 labelled radiotracers for imaging the GABA(A) receptor.
Topics: Flumazenil; Fluorine Radioisotopes; Humans; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, GABA-A; Small Molecule Libraries | 2013 |
Relationship between benzodiazepine receptor occupancy and potentiation of gamma-aminobutyric acid-stimulated chloride flux in vitro of four ligands of differing intrinsic efficacies.
Topics: Animals; Benzodiazepinones; Cell Membrane; Cerebral Cortex; Chlorides; Diazepam; Drug Synergism; Flumazenil; gamma-Aminobutyric Acid; Ligands; Male; Rats; Receptors, GABA-A; Triazolam | 1992 |
Relationship between benzodiazepine receptor occupancy and functional effects in vivo of four ligands of differing intrinsic efficacies.
Topics: Administration, Oral; Animals; Benzodiazepinones; Diazepam; Dose-Response Relationship, Drug; Female; Flumazenil; Male; Mice; Mice, Inbred DBA; Motor Activity; Receptors, GABA-A; Seizures; Triazolam | 1992 |
Changes in benzodiazepine-receptor activity modify morphine withdrawal syndrome in mice.
Topics: Animals; Azides; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Flumazenil; Flunitrazepam; Male; Mice; Morphine; Receptors, GABA-A; Substance Withdrawal Syndrome | 1992 |
In vivo bidirectional modulatory effect of benzodiazepine receptor ligands on GABAergic transmission evaluated by positron emission tomography in non-human primates.
Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Carbolines; Cerebral Cortex; Diazepam; Electroencephalography; Flumazenil; gamma-Aminobutyric Acid; Ligands; Male; Papio; Pentylenetetrazole; Receptors, GABA-A; Seizures; Synaptic Transmission; Tomography, Emission-Computed | 1991 |
Behavioral analysis of the effects of benzodiazepine receptor ligands in the conditioned burying paradigm.
Topics: Animals; Arousal; Benzodiazepinones; Brain; Carbolines; Conditioning, Classical; Diazepam; Dose-Response Relationship, Drug; Electroshock; Fear; Flumazenil; Grooming; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stereotyped Behavior | 1990 |
Partial agonists of the benzodiazepine receptor: from animal data to results in patients.
Topics: Affinity Labels; Allosteric Site; Animals; Azides; Benzodiazepines; Benzodiazepinones; Chlordiazepoxide; Chlorides; Clonazepam; Diazepam; Drug Interactions; Ethanol; Flumazenil; Flurazepam; Humans; Ion Channels; Ligands; Models, Neurological; Neurons; Receptors, GABA-A | 1988 |
Relationship of agonist efficacy to changes in GABA sensitivity and anticonvulsant tolerance following chronic benzodiazepine ligand exposure.
Topics: Animals; Anticonvulsants; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Bicuculline; Brain Chemistry; Diazepam; Drug Tolerance; Electrophysiology; Flumazenil; gamma-Aminobutyric Acid; Male; Raphe Nuclei; Rats; Rats, Inbred Strains; Seizures | 1989 |
Stereospecific transduction of behavioral effects via diazepam-insensitive GABAA receptors.
Topics: Animals; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Binding Sites; Binding, Competitive; Columbidae; Diazepam; Discrimination Learning; Flumazenil; GABA Modulators; Imidazoles; Male; Midazolam; Oxadiazoles; Radioligand Assay; Receptors, GABA-A; Sensitivity and Specificity; Stereoisomerism | 1995 |
Chlordiazepoxide, but not bretazenil, produces acute dependence, as evidenced by disruptions in schedule-controlled behavior.
Topics: Animals; Benzodiazepinones; Chlordiazepoxide; Conditioning, Operant; Flumazenil; Male; Rats; Reinforcement Schedule; Substance Withdrawal Syndrome; Substance-Related Disorders | 1994 |
The benzodiazepine receptor partial agonist bretazenil and the partial inverse agonist Ro 15-4513: effects on salt preference and aversion in the rat.
Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Flumazenil; Food Preferences; Male; Rats; Receptors, GABA-A; Saline Solution, Hypertonic; Sodium Chloride; Taste | 1993 |
Imidazenil: a new partial positive allosteric modulator of gamma-aminobutyric acid (GABA) action at GABAA receptors.
Topics: Allosteric Regulation; Animals; Benzodiazepines; Benzodiazepinones; Chloride Channels; Conflict, Psychological; Diazepam; Flumazenil; gamma-Aminobutyric Acid; Imidazoles; Male; Membrane Proteins; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reflex; Seizures | 1993 |
Expression and pharmacology of human GABAA receptors containing gamma 3 subunits.
Topics: Amino Acid Sequence; Animals; Anti-Anxiety Agents; Base Sequence; Benzodiazepines; Benzodiazepinones; Carbolines; Flumazenil; Flunitrazepam; GABA Modulators; Humans; Molecular Sequence Data; Pyrazoles; Pyridazines; Pyridines; Receptors, GABA-A; Recombinant Proteins; Sequence Homology, Amino Acid; Triazolam; Xenopus; Zolpidem | 1995 |
Pharmacological profile of benzodiazepine site ligands with recombinant GABAA receptor subtypes.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Cell Line; Flumazenil; GABA Modulators; Humans; Rats; Receptors, GABA-A; Recombinant Proteins; Transfection; Triazolam | 1996 |
Blockade of behavioral effects of bretazenil by flumazenil and ZK 93,426 in pigeons.
Topics: Animals; Behavior, Animal; Benzodiazepinones; Carbolines; Columbidae; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; GABA Antagonists; GABA Modulators; Male; Midazolam; Punishment; Receptors, GABA | 1997 |
GABA(A) receptors containing the alpha4-subunit: prevalence, distribution, pharmacology, and subunit architecture in situ.
Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Brain; Cell Membrane; Cerebellum; Diazepam; Flumazenil; Immunohistochemistry; Immunosorbent Techniques; Macromolecular Substances; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins | 1997 |
Dissociation of consummatory and vocal components of feeding in squirrel monkeys treated with benzodiazepines and alcohol.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Chlordiazepoxide; Conditioning, Classical; Consummatory Behavior; Ethanol; Feeding Behavior; Flumazenil; Saimiri; Social Behavior; Vocalization, Animal | 1998 |
Benzodiazepine modulation of recombinant alpha1beta3gamma2 GABA(A) receptor function efficacy determination using the Cytosensor microphysiometer.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Biosensing Techniques; Cell Count; Cells, Cultured; Dose-Response Relationship, Drug; Eukaryotic Cells; Flumazenil; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Humans; Pyridines; Receptors, GABA-A; Recombinant Proteins; Time Factors; Zolpidem | 1998 |
Molecular structure and stereoelectronic properties of sarmazenil--a weak inverse agonist at the omega modulatory sites (benzodiazepine receptors): comparison with bretazenil and flumazenil.
Topics: Benzodiazepines; Benzodiazepinones; Binding Sites; Crystallography, X-Ray; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Imidazoles; Models, Molecular; Molecular Conformation; Molecular Structure | 1998 |
Apparent pA2 values of benzodiazepine antagonists and partial agonists in monkeys.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Binding Sites; Binding, Competitive; Carbolines; Dose-Response Relationship, Drug; Electroshock; Feeding Behavior; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Kinetics; Male; Midazolam; Receptors, GABA-A; Reinforcement Schedule; Saimiri | 1999 |
Role of the histidine residue at position 105 in the human alpha 5 containing GABA(A) receptor on the affinity and efficacy of benzodiazepine site ligands.
Topics: Anticonvulsants; Arginine; Azides; Benzodiazepines; Benzodiazepinones; Binding Sites; Binding, Competitive; Cell Line; Cells, Cultured; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Histidine; Humans; Ligands; Mutation; Protein Subunits; Receptors, GABA-A | 2002 |
Comparison of the behavioral effects of bretazenil and flumazenil in triazolam-dependent and non-dependent baboons.
Topics: Animals; Behavior, Animal; Benzodiazepinones; Dose-Response Relationship, Drug; Eating; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Infusions, Parenteral; Male; Papio; Psychomotor Performance; Substance Withdrawal Syndrome; Substance-Related Disorders; Triazolam | 2005 |
Selective labelling of diazepam-insensitive GABAA receptors in vivo using [3H]Ro 15-4513.
Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Cerebellum; Flumazenil; Humans; Isotope Labeling; Ligands; Lorazepam; Male; Mice; Mice, Transgenic; Prosencephalon; Receptors, GABA-A; Receptors, GABA-B; Tritium | 2005 |
Contribution of specific binding to the central benzodiazepine site to the brain concentrations of two novel benzodiazepine site ligands.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Binding Sites; Binding, Competitive; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; GABA Modulators; GABA-A Receptor Agonists; Injections, Intravenous; Ligands; Male; Mice; Mice, Mutant Strains; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tissue Distribution; Triazines | 2007 |
GABA(A) receptor α subunits differentially contribute to diazepam tolerance after chronic treatment.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Benzodiazepinones; Body Temperature; Brain; Diazepam; DNA Primers; Drug Tolerance; Flumazenil; Hypnotics and Sedatives; In Situ Hybridization; Male; Mice; Mice, Mutant Strains; Pyridazines; Pyridines; Receptors, GABA-A; Triazoles; Zolpidem | 2012 |