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brequinar and uridine triphosphate

brequinar has been researched along with uridine triphosphate in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, TL; Erlichman, C1
de Kant, E; Laurensse, EJ; Nadal, JC; Peters, GJ; Pinedo, HM1
Blinder, L; Chong, AS; Gong, H; Shen, J; Williams, JW; Xu, X1
Carrey, EA; Fairbanks, LD; Hawrylowicz, CM; Kirschbaum, B; Richards, DF; Rückemann, K; Simmonds, HA1

Other Studies

4 other study(ies) available for brequinar and uridine triphosphate

ArticleYear
Biochemical modulation of 5-fluorouracil with or without leucovorin by a low dose of brequinar in MGH-U1 cells.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Cell Survival; Cytidine Triphosphate; Deoxyuracil Nucleotides; Dose-Response Relationship, Drug; Drug Interactions; Fluorodeoxyuridylate; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; Leucovorin; Phosphoribosyl Pyrophosphate; Thymidylate Synthase; Tumor Cells, Cultured; Uridine Triphosphate

1992
Retention of in vivo antipyrimidine effects of Brequinar sodium (DUP-785; NSC 368390) in murine liver, bone marrow and colon cancer.
    Biochemical pharmacology, 1990, Jan-01, Volume: 39, Issue:1

    Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Bone Marrow; Colonic Neoplasms; Dihydroorotate Oxidase; Female; Liver; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oxidoreductases; Pyrimidine Nucleotides; Uridine; Uridine Triphosphate

1990
Control of lymphoproliferative and autoimmune disease in MRL-lpr/lpr mice by brequinar sodium: mechanisms of action.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:2

    Topics: Animals; Autoantibodies; Autoimmune Diseases; Biphenyl Compounds; Cytidine Triphosphate; Female; Immunosuppressive Agents; Isoxazoles; Leflunomide; Lymphoproliferative Disorders; Mice; Mice, Inbred BALB C; Mice, Inbred MRL lpr; Phosphorylation; Tyrosine; Uridine; Uridine Triphosphate

1997
Leflunomide inhibits pyrimidine de novo synthesis in mitogen-stimulated T-lymphocytes from healthy humans.
    The Journal of biological chemistry, 1998, Aug-21, Volume: 273, Issue:34

    Topics: Adenosine Triphosphate; Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Chromatography, High Pressure Liquid; Dihydroorotate Dehydrogenase; Humans; Immunosuppressive Agents; In Vitro Techniques; Isoxazoles; Leflunomide; Lymphocyte Activation; Mice; Mitogens; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Phytohemagglutinins; Pyrimidines; T-Lymphocytes; Uridine; Uridine Triphosphate

1998