brequinar has been researched along with sirolimus in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 20 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thomson, AW | 1 |
| Morris, RE | 1 |
| Surdacka, E; Surdacki, A; Sułowicz, W | 1 |
| Kahan, BD | 2 |
| Bumgardner, GL; Roberts, JP | 1 |
| Morris, RE; Murphy, MP | 1 |
| Ericzon, BG; Gannedahl, G; Groth, CG; Ohlman, S | 1 |
| Chou, TC; Kahan, BD; Stepkowski, SM; Tu, Y | 2 |
| Chee, C; Chou, T; Kahan, BD; Stepkowski, S; Tejpal, N; Wang, M | 1 |
| Ferraresso, M; Kahan, BD; Knight, R; Stepkowski, SM; Tu, Y | 1 |
| Bach, FH; Blakely, ML; Dalmasso, AP; Van der Werf, WJ | 1 |
| Kahan, BD; Stepkowski, SM; Tu, Y; Wang, M | 1 |
| Chou, TC; Gibbons-Stubbers, S; Kahan, BD; Stepkowski, S; Tejpal, N; Tu, Y; Wang, M | 1 |
| Kahan, BD; Stepkowski, SM | 1 |
| Chou, TC; Kahan, BD; Qu, X; Stepkowski, SM; Wang, M | 1 |
| Halloran, PF | 1 |
| Alexander, JW; Levy, AE | 1 |
| Kahan, BD; Qu, X; Stepkowski, SM; Tian, L; Wang, M; Wang, ME; Yu, J | 1 |
9 review(s) available for brequinar and sirolimus
| Article | Year |
|---|---|
The spectrum of action of new immunosuppressive drugs.
Topics: Animals; Biphenyl Compounds; Cyclosporine; Guanidines; Humans; Immunosuppressive Agents; Polyenes; Sirolimus; Tacrolimus | 1992 |
Immunopharmacology of new xenobiotic immunosuppressive molecules.
Topics: Animals; Biphenyl Compounds; Cyclosporine; Graft Rejection; Guanidines; Humans; Immunosuppressive Agents; Mycophenolic Acid; Polyenes; Ribonucleosides; Sirolimus; Tacrolimus; Xenobiotics | 1992 |
[New immunosuppressive drugs in transplantation].
Topics: Biphenyl Compounds; Cyclosporine; Guanidines; Humans; Immunosuppressive Agents; Mycophenolic Acid; Polyenes; Ribonucleosides; Sirolimus; Spiro Compounds; Tacrolimus; Transplantation Immunology | 1994 |
New immunosuppressive drugs--pharmacologic approaches to alter immunoregulation.
Topics: Animals; Antimetabolites; Azathioprine; Biphenyl Compounds; Cell Differentiation; Cyclosporine; Guanidines; Humans; Immunosuppressive Agents; Isoxazoles; Leflunomide; Lymphocytes; Lymphokines; Oligonucleotides, Antisense; Polyenes; Receptors, Cytokine; Ribonucleosides; Signal Transduction; Sirolimus; Tacrolimus | 1994 |
New immunosuppressive agents.
Topics: Alprostadil; Animals; Antibodies, Monoclonal; Biphenyl Compounds; Child; Disease Models, Animal; Dogs; Guanidines; Humans; Immunosuppressive Agents; Liver Transplantation; Mycophenolic Acid; Polyenes; Rats; Sirolimus; Tacrolimus | 1993 |
New immunosuppressive drugs in transplantation.
Topics: Biphenyl Compounds; Cyclosporins; Guanidines; Humans; Immunosuppressive Agents; Kidney; Mycophenolic Acid; Polyenes; Sirolimus; T-Lymphocytes; Tacrolimus; Transplantation Immunology | 1993 |
Concentration-controlled immunosuppressive regimens using cyclosporine with sirolimus or brequinar in human renal transplantation.
Topics: Biphenyl Compounds; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Kidney Transplantation; Models, Theoretical; Polyenes; Sirolimus | 1995 |
Synergistic effects of cyclosporin analogs--A, D, G, IMM-125--with rapamycin and/or brequinar.
Topics: Animals; Biphenyl Compounds; Cyclosporine; Cyclosporins; Drug Synergism; Humans; Immunosuppressive Agents; Lymphocyte Activation; Models, Biological; Polyenes; Sirolimus; Transplantation Immunology | 1994 |
Molecular mechanisms of new immunosuppressants.
Topics: Amino Acid Isomerases; B-Lymphocytes; Biphenyl Compounds; Calcineurin; Calmodulin-Binding Proteins; Carrier Proteins; Cyclosporine; Enzyme Inhibitors; Humans; Immunosuppressive Agents; IMP Dehydrogenase; Isoxazoles; Leflunomide; Mycophenolic Acid; Oxidoreductases; Peptidylprolyl Isomerase; Phosphoprotein Phosphatases; Polyenes; Purines; Pyrimidines; Receptors, Cytokine; Ribonucleosides; Signal Transduction; Sirolimus; T-Lymphocytes; Tacrolimus | 1996 |
11 other study(ies) available for brequinar and sirolimus
| Article | Year |
|---|---|
Brequinar sodium effectively and potently suppresses allograft rejection in a heterotopic mouse heart transplant model.
Topics: Animals; Biphenyl Compounds; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Graft Rejection; Heart Transplantation; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Models, Biological; Polyenes; Sirolimus; Tacrolimus; Transplantation, Homologous | 1993 |
The synergistic effects of cyclosporine, sirolimus, and brequinar on heart allograft survival in mice.
Topics: Animals; Biphenyl Compounds; Cyclosporine; Dose-Response Relationship, Drug; Drug Synergism; Female; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Models, Biological; Polyenes; Sirolimus | 1995 |
Synergistic interactions of cyclosporine, rapamycin, and brequinar on heart allograft survival in mice.
Topics: Animals; Biphenyl Compounds; Cyclosporine; Drug Synergism; Drug Therapy, Combination; Female; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Polyenes; Sirolimus; Transplantation, Homologous | 1994 |
Triple combination of cyclosporine, brequinar, and rapamycin prolongs kidney allograft survival in the mongrel dog.
Topics: Animals; Biphenyl Compounds; Cyclosporine; Dogs; Drug Synergism; Drug Therapy, Combination; Female; Graft Survival; Immunosuppressive Agents; Kidney Transplantation; Male; Polyenes; Sirolimus; Transplantation, Homologous | 1994 |
Anti-B cell agents: suppression of natural antibodies and prolongation of survival in discordant xenografts.
Topics: Animals; Antibodies, Heterophile; Antibody Formation; B-Lymphocytes; Biphenyl Compounds; Cyclosporine; Graft Survival; Guinea Pigs; Immunosuppression Therapy; Immunosuppressive Agents; Mycophenolic Acid; Polyenes; Rats; Rats, Inbred Lew; Sirolimus; Splenectomy; Time Factors; Transplantation, Heterologous | 1994 |
Effect of cyclosporine alone or in combination with rapamycin and brequinar on survival of hamster heart xenograft in rats.
Topics: Animals; Biphenyl Compounds; Cricetinae; Cyclosporine; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Male; Mesocricetus; Polyenes; Rats; Rats, Inbred Lew; Sirolimus; Transplantation, Heterologous | 1993 |
The synergistic interactions in vitro and in vivo of brequinar sodium with cyclosporine or rapamycin alone and in triple combination.
Topics: Antibodies; Biphenyl Compounds; CD3 Complex; Cell Line; Cyclosporine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Interleukin-2; Lymphocyte Culture Test, Mixed; Phytohemagglutinins; Polyenes; Sirolimus; T-Lymphocytes, Cytotoxic | 1993 |
Synergistic activity of the triple combination: cyclosporine, rapamycin, and brequinar.
Topics: Administration, Oral; Animals; Biphenyl Compounds; Cyclosporine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Injections, Intravenous; Male; Polyenes; Rats; Rats, Inbred WF; Sirolimus; Transplantation, Homologous | 1993 |
Beneficial effect of graft perfusion with anti-T cell receptor monoclonal antibodies on survival of small bowel allografts in rat recipients treated with brequinar alone or in combination with cyclosporine and sirolimus.
Topics: Animals; Antibodies, Monoclonal; Antilymphocyte Serum; Biphenyl Compounds; Cyclosporine; Graft Survival; Graft vs Host Disease; Graft vs Host Reaction; Host vs Graft Reaction; Immune Tolerance; Immunosuppressive Agents; Intestine, Small; Male; Perfusion; Polyenes; Rats; Rats, Inbred ACI; Rats, Inbred BN; Rats, Inbred Lew; Receptors, Antigen, T-Cell, alpha-beta; Sirolimus; Time Factors; Transplantation, Homologous | 1996 |
The significance of timing of additional short-term immunosuppression in the donor-specific transfusion/cyclosporine-treated rat.
Topics: Animals; Antilymphocyte Serum; Biphenyl Compounds; Blood Donors; Blood Transfusion; Cyclosporine; Drug Administration Schedule; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Male; Methylprednisolone; Polyenes; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Sirolimus; Time Factors | 1996 |
Cytokine mRNA expression in tolerant heart allografts after immunosuppression with cyclosporine, sirolimus or brequinar.
Topics: Animals; Biphenyl Compounds; Cyclosporine; Cytokines; Epitopes; Heart Transplantation; Immunosuppressive Agents; Interferon-gamma; Interleukins; Isoantigens; Lymphocyte Activation; Male; Polyenes; Polymerase Chain Reaction; Rats; Rats, Inbred Strains; RNA, Messenger; Sirolimus; Th1 Cells; Th2 Cells | 1997 |