Compounds > brequinar
Page last updated: 2024-08-24

brequinar and nsc-126771

brequinar has been researched along with nsc-126771 in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Chen, Q; Liu, H; Liu, X; Luo, Y; Qian, X; Sang, N; Su, N; Tao, L; Yu, Y; Zeng, T; Zhao, Y; Zhou, X; Zhou, Y; Zuo, Z1
Behrens, DL; Chen, SF; Papp, LM; Perrella, FW1
Ardalan, K; Cleaveland, ES; Cooney, DA; Ford, H; Monks, A; Paull, K; Vaigro-Wolff, A; Zaharevitz, DW1
Peters, GJ1

Other Studies

4 other study(ies) available for brequinar and nsc-126771

ArticleYear
Bifunctional Naphtho[2,3-
    Journal of medicinal chemistry, 2020, 07-23, Volume: 63, Issue:14

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dihydroorotate Dehydrogenase; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Humans; Male; Membrane Potential, Mitochondrial; Mice, Inbred BALB C; Mice, SCID; Molecular Docking Simulation; Molecular Structure; Naphthoquinones; Oxidoreductases Acting on CH-CH Group Donors; Protein Binding; Rats, Sprague-Dawley; Reactive Oxygen Species; S Phase Cell Cycle Checkpoints; Structure-Activity Relationship; Triazoles

2020
Inhibition of dihydroorotate dehydrogenase activity by brequinar sodium.
    Cancer research, 1992, Jul-01, Volume: 52, Issue:13

    Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Dihydroorotate Dehydrogenase; Kinetics; Leukemia L1210; Mice; Naphthoquinones; Orotic Acid; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors

1992
Site of action of two novel pyrimidine biosynthesis inhibitors accurately predicted by the compare program.
    Biochemical pharmacology, 1995, Mar-30, Volume: 49, Issue:7

    Topics: Aminobiphenyl Compounds; Antineoplastic Agents; Binding Sites; Biphenyl Compounds; Cell Division; Dihydroorotate Dehydrogenase; Humans; Imidazoles; Naphthoquinones; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Pyrimidines; Software; Structure-Activity Relationship; Tumor Cells, Cultured

1995
Antipyrimidine effects of five different pyrimidine de novo synthesis inhibitors in three head and neck cancer cell lines.
    Nucleosides, nucleotides & nucleic acids, 2018, Volume: 37, Issue:6

    Topics: Amides; Antineoplastic Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Biphenyl Compounds; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carcinoma, Squamous Cell; Cell Line, Tumor; Dihydroorotate Dehydrogenase; Head and Neck Neoplasms; Humans; Isoxazoles; Naphthoquinones; Orotate Phosphoribosyltransferase; Oxidoreductases Acting on CH-CH Group Donors; Phosphonoacetic Acid; Purine Nucleotides; Pyrazoles; Pyrimidine Nucleotides; Ribonucleosides; Ribose

2018