bremazocine has been researched along with morphinans in 55 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 47 (85.45) | 18.7374 |
| 1990's | 6 (10.91) | 18.2507 |
| 2000's | 2 (3.64) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fiorica-Howells, E; Spector, S | 1 |
| Devlin, T; Shoemaker, WJ | 1 |
| Baumann, NA; Cabon, F; Cupo, A; Ruiz-Gayo, M; Zalc, B | 1 |
| Craft, RM; Negus, SS; Picker, MJ | 1 |
| Scheideler, MA; Zukin, RS | 1 |
| Bergman, J; Warren, PH | 1 |
| Herz, A; Morris, BJ | 2 |
| Heijna, MH; Hogenboom, F; Mulder, AH; Portoghese, PS; Schoffelmeer, AN | 1 |
| Huidobro-Toro, JP; Roblero, J; Salas, SP; Ureta, H | 1 |
| Christensen, JD; Fjalland, B; Grell, S | 1 |
| Birchmore, B; Hughes, J; Hunter, JC; Woodruff, R | 1 |
| Magnan, J; Tiberi, M | 1 |
| Deviche, P; Lowry, CA; Moore, FL | 1 |
| Dykstra, LA; Picker, MJ | 1 |
| Dykstra, LA; Negus, SS; Picker, MJ | 1 |
| Hill, RG; Hughes, J; Hunter, JC; Smith, JA | 1 |
| Deviche, P; Moore, FL | 1 |
| Crema, G; Gioannini, TL; Hiller, JM; Simon, EJ | 1 |
| Magnan, J; Pilapil, C; Quirion, R | 1 |
| Frey, HH | 1 |
| Barlow, JJ; Carroll, JA; Costello, GF; Main, BG; Shaw, JS | 1 |
| Bhargava, HN; Gulati, A | 1 |
| De Montis, GM; Devoto, P; Preti, A; Tagliamonte, A | 1 |
| Buydens, P; Finné, E; Govaerts, J; Vanhaelst, L; Velkeniers, B | 1 |
| Ensinger, HA | 1 |
| Richards, ML; Sadée, W | 1 |
| Conway, S; Koenig, JI; Krulich, L; Mayfield, MA; McCann, SM | 2 |
| Shearman, GT; Stenfors, C | 1 |
| Corbett, AD; Kosterlitz, HW | 1 |
| Dunwiddie, TV; Johnson, KJ; Proctor, WR | 1 |
| Calcagnetti, DJ; Cramer, CP; Fanselow, MS; Helmstetter, FJ | 1 |
| Bakalkin, GIa; Kobylianskiĭ, AG; Tsibul'skiĭ, VL | 1 |
| Brooks, AN; Lamming, GE; Peters, AR; Short, RE | 1 |
| Leander, JD | 2 |
| Castellano, C; Pavone, F | 2 |
| Reubi, JC | 1 |
| Huidobro-Toro, JP; Parada, S | 1 |
| Maurer, R | 1 |
| Ben-Sreti, MM; Gonzalez, JP; Sewell, RD | 1 |
| Fuller, RW; Leander, JD | 1 |
| Akkerman, AM; Bakel, HC; Büscher, H; Hill, RC; Maurer, R; Petcher, TJ; Römer, D; Welle, HB | 1 |
| Gähwiler, BH; Maurer, R | 1 |
| Freye, E; Hartung, E; Schenk, GK | 1 |
| Hartig, U; Opitz, K | 1 |
| Flórez, J; Pazos, A; Tristán, C | 1 |
| Gambino, MC; Petrillo, P; Tavani, A | 1 |
| Markó, M; Römer, D | 1 |
| Herz, A; Shearman, GT | 1 |
| Mash, DC; Partilla, J; Rice, KC; Rothman, RB; Staley, JK | 1 |
| Aceto, MD; Breeden, S; Broadbear, J; Grundt, P; Husbands, SM; Lewis, JW; Neilan, CL; Traynor, JR; Woods, JH | 1 |
| Husbands, SM; Ko, MC | 1 |
55 other study(ies) available for bremazocine and morphinans
| Article | Year |
|---|---|
Selectivity of some "specific" opioid ligands?
Topics: Animals; Benzomorphans; Binding, Competitive; Brain; Dynorphins; Female; Haloperidol; In Vitro Techniques; Mice; Morphinans; Peptide Fragments; Phencyclidine; Piperidines; Receptors, Opioid | 1990 |
Characterization of kappa opioid binding using dynorphin A1-13 and U69,593 in the rat brain.
Topics: Analgesics; Animals; Benzeneacetamides; Benzomorphans; Binding, Competitive; Brain; Culture Techniques; Dynorphins; Ligands; Male; Morphinans; Peptide Fragments; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Tritium | 1990 |
Pharmacological and molecular properties of opioid binding sites synthesized in a cell-free translation system.
Topics: Animals; Benzomorphans; Binding, Competitive; Cell Line; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hybridomas; Mice; Molecular Weight; Morphinans; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; RNA, Messenger | 1990 |
Butorphanol's efficacy at mu and kappa opioid receptors: inferences based on the schedule-controlled behavior of nontolerant and morphine-tolerant rats and on the responding of rats under a drug discrimination procedure.
Topics: Analgesics; Animals; Behavior, Animal; Benzomorphans; Butorphanol; Discrimination, Psychological; Drug Tolerance; Male; Morphinans; Morphine; Narcotic Antagonists; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reinforcement Schedule | 1990 |
Reconstitution of solubilized delta-opiate receptor binding sites in lipid vesicles.
Topics: Animals; Benzomorphans; Binding Sites; Cell Line; Cell Membrane; Chromatography, Affinity; Glioma; Kinetics; Liposomes; Morphinans; Neuroblastoma; Phospholipids; Receptors, Opioid; Receptors, Opioid, delta; Solubility | 1990 |
Effects of kappa opioids on schedule-controlled behavior of squirrel monkeys.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzomorphans; Conditioning, Psychological; Dose-Response Relationship, Drug; Electroshock; Male; Morphinans; Morphine; Naltrexone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Saimiri | 1989 |
Control of opiate receptor number in vivo: simultaneous kappa-receptor down-regulation and mu-receptor up-regulation following chronic agonist/antagonist treatment.
Topics: Animals; Benzomorphans; Binding, Competitive; Endorphins; Male; Morphinans; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1989 |
Mu- and delta-opioid receptor-mediated inhibition of adenylate cyclase activity stimulated by released endogenous dopamine in rat neostriatal slices; demonstration of potent delta-agonist activity of bremazocine.
Topics: Adenylyl Cyclases; Amphetamine; Animals; Benzomorphans; Corpus Striatum; Cyclic AMP; Dopamine; Drug Interactions; Male; Morphinans; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid | 1989 |
Diuretic effect of bremazocine, a kappa-opioid with central and peripheral sites of action.
Topics: Animals; Benzomorphans; Blood Pressure; Brain; Diuresis; Female; Glomerular Filtration Rate; Kidney; Kidney Concentrating Ability; Male; Morphinans; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Water-Electrolyte Balance | 1989 |
Biphasic effect of a kappa-opioid receptor agonist on plasma oxytocin levels in rats.
Topics: Analgesics; Animals; Benzomorphans; Body Water; Brain Chemistry; Female; In Vitro Techniques; Male; Morphinans; Naloxone; Oxytocin; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Sodium; Time Factors | 1989 |
Kappa opioid binding sites in the dog cerebral cortex and spinal cord.
Topics: Animals; Benzeneacetamides; Benzomorphans; Cerebral Cortex; Dogs; Morphinans; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Spinal Cord | 1989 |
Pharmacological characterization of the binding of [3H]bremazocine in guinea-pig brain: evidence for multiplicity of the kappa-opioid receptors.
Topics: Animals; Benzomorphans; Brain; Cyclazocine; Ethylketocyclazocine; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Membranes; Models, Biological; Morphinans; Muscle, Smooth; Peptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stereoisomerism | 1989 |
Opiate control of spontaneous locomotor activity in a urodele amphibian.
Topics: Animals; Benzomorphans; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Morphinans; Motor Activity; Naloxone; Receptors, Opioid; Receptors, Opioid, kappa; Salamandridae | 1989 |
Discriminative stimulus effects of mu and kappa opioids in the pigeon: analysis of the effects of full and partial mu and kappa agonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Benzomorphans; Columbidae; Cyclazocine; Discrimination Learning; Ethylketocyclazocine; Fentanyl; Morphinans; Naloxone; Narcotics; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1989 |
Opioid-like discriminative stimulus properties of benzomorphans in the pigeon: stereospecificity and differential substitution patterns.
Topics: Analgesics; Animals; Benzomorphans; Columbidae; Discrimination Learning; Fentanyl; Morphinans; Racemases and Epimerases; Stereoisomerism; Water | 1989 |
A kinetic analysis of kappa-opioid agonist binding using the selective radioligand [3H]U69593.
Topics: Animals; Benzeneacetamides; Benzomorphans; Binding, Competitive; Guinea Pigs; Kinetics; Male; Morphinans; Pyrrolidines; Radioligand Assay; Tritium | 1989 |
Opioid kappa-receptor agonists suppress sexual behaviors in male rough-skinned newts (Taricha granulosa).
Topics: Analgesics; Animals; Benzomorphans; Cyclazocine; Ethylketocyclazocine; Male; Morphinans; Morphine; Naloxone; Receptors, Opioid; Salamandridae; Sexual Behavior, Animal | 1987 |
The direct demonstration of binding of mu, delta and kappa agonists to digitonin-solubilized opioid receptors from bovine striatum.
Topics: Analgesics; Animals; Benzomorphans; Cattle; Cell Membrane; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Kinetics; Morphinans; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1986 |
Localization of kappa opioid receptor binding sites in human forebrain using [3H]U69,593: comparison with [3H]bremazocine.
Topics: Autoradiography; Benzeneacetamides; Benzomorphans; Binding Sites; Brain; Humans; In Vitro Techniques; Morphinans; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Tissue Distribution | 1987 |
Effect of mu- and kappa-opioid agonists on the electroconvulsive seizure threshold in mice and antagonism by naloxone and MR 2266.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzeneacetamides; Benzodiazepines; Benzomorphans; Electroshock; Fentanyl; Male; Mice; Morphinans; Morphine; Nalbuphine; Naloxone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Seizures | 1988 |
A novel series of potent and selective agonists at the opioid kappa-receptor.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Mice; Morphinans; Muscle Contraction; Muscle, Smooth; Naloxone; Narcotics; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa | 1988 |
Cardiovascular responses to kappa opioid agonists in intact and adrenal demedullated rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenal Medulla; Animals; Benzomorphans; Blood Pressure; Cardiovascular System; Dose-Response Relationship, Drug; Heart Rate; Male; Morphinans; Naltrexone; Narcotic Antagonists; Pyrrolidines; Rats; Rats, Inbred Strains; Tape Recording | 1988 |
Differential effect of mu, delta, and kappa opioid agonists on adenylate cyclase activity.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclases; Analgesics; Animals; Benzeneacetamides; Benzomorphans; Corpus Striatum; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Male; Morphinans; Peptide Fragments; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid | 1987 |
The effect of bombesin on basal, alpha-methyl-p-tyrosine, haloperidol, morphine, bremazocine and stress-induced prolactin secretion.
Topics: alpha-Methyltyrosine; Analgesics; Animals; Benzomorphans; Bombesin; Haloperidol; Male; Methyltyrosines; Morphinans; Prolactin; Rats; Rats, Inbred Strains; Reference Values; Restraint, Physical; Stress, Psychological; Tyrosine 3-Monooxygenase | 1988 |
Differentiating aspects of opioid receptor binding by [3H](-) (1R,5R,9R,2''S)-5,9-dimethyl-2-tetrahydrofurfuryl-2'-hydroxy-6,7- benzomorphan hydrochloride ([3H]Mr 2034), a drug preferentially acting on kappa-receptors.
Topics: Animals; Benzomorphans; Binding, Competitive; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; In Vitro Techniques; Kinetics; Male; Morphinans; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, kappa | 1985 |
In vivo binding of benzomorphans to mu, delta and kappa opioid receptors: comparison with urine output in the rat.
Topics: Animals; Benzomorphans; Brain; Diprenorphine; Diuresis; Morphinans; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1985 |
Opioid kappa receptors and the secretion of prolactin (PRL) and growth hormone (GH) in the rat. I. Effects of opioid kappa receptor agonists bremazocine and U-50,488 on secretion of PRL and GH: comparison with morphine.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Dose-Response Relationship, Drug; Growth Hormone; Injections, Intravenous; Male; Morphinans; Morphine; Naloxone; Prolactin; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Time Factors | 1986 |
Opioid kappa receptors and the secretion of prolactin (PRL) and growth hormone (GH) in the rat. II. GH and PRL release-inhibiting effects of the opioid kappa receptor agonists bremazocine and U-50,488.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Clonidine; Growth Hormone; Injections, Intravenous; Male; Morphinans; Morphine; Prolactin; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Serotonin; Time Factors | 1986 |
Bremazocine-induced backwards walking behavior in rats is mediated via opioid kappa receptors.
Topics: Animals; Benzomorphans; Brain; Hallucinogens; Locomotion; Male; Morphinans; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa | 1986 |
Autoradiographic localization in rat brain of kappa opiate binding sites labelled by [3H]bremazocine.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Autoradiography; Benzomorphans; Binding Sites; Binding, Competitive; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Morphinans; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa | 1986 |
Bremazocine is an agonist at kappa-opioid receptors and an antagonist at mu-opioid receptors in the guinea-pig myenteric plexus.
Topics: Animals; Benzomorphans; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Morphinans; Myenteric Plexus; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1986 |
Bremazocine differentially antagonizes responses to selective mu and delta opioid receptor agonists in rat hippocampus.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Electric Stimulation; Electrodes; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hippocampus; In Vitro Techniques; Male; Morphinans; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1987 |
Ethylketocyclazocine and bremazocine analgesia in neonatal rats.
Topics: Analgesia; Analgesics; Animals; Animals, Newborn; Benzomorphans; Cyclazocine; Ethylketocyclazocine; Female; Male; Morphinans; Naltrexone; Narcotic Antagonists; Rats | 1988 |
[Ability of the opiate kappa-agonist bremazocine to facilitate the flexor reflex of the right hindlimb in spinal rats].
Topics: Analgesics; Animals; Benzomorphans; Electromyography; Hindlimb; Male; Morphinans; Muscles; Rats; Reflex; Spinal Cord | 1988 |
Opioid modulation of LH secretion during the oestrous cycle of heifers.
Topics: Animals; Azocines; Benzomorphans; Cattle; Estrus; Female; Follicular Phase; Luteinizing Hormone; Morphinans; Narcotic Antagonists; Secretory Rate | 1987 |
Bremazocine-induced urination in rats of different sizes.
Topics: Analgesics; Animals; Benzomorphans; Body Weight; Dose-Response Relationship, Drug; Male; Morphinans; Rats; Urination | 1987 |
Effects of bremazocine on passive avoidance behaviour in mice.
Topics: Analgesics; Animals; Avoidance Learning; Benzomorphans; Male; Mice; Mice, Inbred DBA; Morphinans; Narcotic Antagonists; Restraint, Physical; Stress, Psychological | 1986 |
Central nervous system-mediated growth inhibition of a rat prostate carcinoma by an opioid.
Topics: Adenocarcinoma; Animals; Benzomorphans; Central Nervous System; Luteinizing Hormone; Male; Morphinans; Organ Size; Prostate; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Testosterone | 1985 |
Effects of bremazocine on locomotor activity in DBA/2 and C57BL/6 mice.
Topics: Analgesics; Animals; Benzomorphans; Haloperidol; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphinans; Motor Activity; Narcotic Antagonists; Receptors, Dopamine; Species Specificity | 1985 |
Kappa-opiates and urination: pharmacological evidence for an endogenous role of the kappa-opiate receptor in fluid and electrolyte balance.
Topics: Animals; Azocines; Benzomorphans; Cyclazocine; Diuresis; Ethylketocyclazocine; Female; Injections, Intraperitoneal; Morphinans; Morphine; Naloxone; Potassium; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium; Water-Electrolyte Balance | 1984 |
Comparative in vitro/in vivo autoradiography using the opiate ligand 3H-(-)-bremazocine.
Topics: Animals; Autoradiography; Benzomorphans; Binding Sites; Brain; In Vitro Techniques; Morphinans; Rats; Receptors, Opioid | 1984 |
Effects of elevated calcium and calcium antagonists on 6,7-benzomorphan-induced analgesia.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Animals; Benzomorphans; Calcium; Calcium Channel Blockers; Cyclazocine; Egtazic Acid; Ethylketocyclazocine; Gallopamil; Male; Mice; Morphinans; Pentazocine; Phenazocine | 1983 |
Further study of kappa opioids on increased urination.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Cyclazocine; Diuresis; Ethylketocyclazocine; Male; Morphinans; Naloxone; Narcotic Antagonists; Narcotics; Piperidines; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Urination | 1983 |
Elevation of serum corticosterone in rats by bremazocine, a kappa-opioid agonist.
Topics: Animals; Benzomorphans; Corticosterone; Dose-Response Relationship, Drug; Male; Morphinans; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa | 1984 |
Bremazocine: a potent, long-acting opiate kappa-agonist.
Topics: Analgesia; Animals; Benzomorphans; Brain; Cyclazocine; Electric Stimulation; Ethylketocyclazocine; Guinea Pigs; Ileum; Macaca mulatta; Male; Mice; Morphinans; Morphine; Naloxone; Pentazocine; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Vas Deferens | 1980 |
Involvement of mu-receptors in the opioid-induced generation of bursting discharges in hippocampal pyramidal cells.
Topics: Animals; Benzomorphans; Culture Techniques; Cyclazocine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dose-Response Relationship, Drug; Electrophysiology; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Hippocampus; Membrane Potentials; Morphinans; Rats; Receptors, Opioid; Receptors, Opioid, mu | 1981 |
Bremazocine: an opiate that induces sedation and analgesia without respiratory depression.
Topics: Analgesics; Animals; Benzomorphans; Blood Gas Analysis; Blood Pressure; Body Temperature; Dogs; Drug Administration Schedule; Evoked Potentials, Somatosensory; Heart Rate; Morphinans; Receptors, Opioid; Receptors, Opioid, kappa; Respiration | 1983 |
The influence of the kappa-agonist bremazocine on ingestive behaviour in mice and rats.
Topics: Analgesics; Animals; Benzomorphans; Dose-Response Relationship, Drug; Drinking; Eating; Female; Mice; Mice, Inbred Strains; Morphinans; Rats; Rats, Inbred Strains; Receptors, Opioid; Species Specificity | 1983 |
A comparative study of the respiratory depressant and analgesic effects of bremazocine, a kappa-agonist.
Topics: Analgesia; Analgesics; Animals; Benzomorphans; Drug Antagonism; Morphinans; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Respiration | 1983 |
Bremazocine induces antinociception, but prevents opioid-induced constipation and catatonia in rats and precipitates withdrawal in morphine-dependent rats.
Topics: Analgesics; Animals; Benzomorphans; Catatonia; Constipation; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Gastrointestinal Motility; Humans; Male; Morphinans; Morphine; Naloxone; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders | 1984 |
Inhibitory effect of a new opioid agonist on reproductive endocrine activity in rats of both sexes.
Topics: Animals; Benzomorphans; Castration; Cells, Cultured; Female; In Vitro Techniques; Luteinizing Hormone; Male; Morphinans; Morphine; Naloxone; Ovulation; Pituitary Gland; Rats; Rats, Inbred Strains; Reproduction; Testis; Time Factors | 1983 |
Discriminative stimulus properties of bremazocine in the rat.
Topics: Analgesics; Animals; Benzomorphans; Cyclazocine; Discrimination Learning; Discrimination, Psychological; Generalization, Stimulus; Male; Morphinans; Narcotics; Rats; Rats, Inbred Strains | 1981 |
Kappa2 opioid receptors in limbic areas of the human brain are upregulated by cocaine in fatal overdose victims.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adult; Amygdala; Benzeneacetamides; Benzomorphans; Binding, Competitive; Brain; Brain Chemistry; Caudate Nucleus; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Drug Overdose; Female; Fentanyl; Gyrus Cinguli; Humans; Isothiocyanates; Kinetics; Male; Morphinans; Protein Binding; Pyrrolidines; Receptors, Opioid, kappa; Tissue Distribution; Up-Regulation | 1997 |
BU74, a complex oripavine derivative with potent kappa opioid receptor agonism and delayed opioid antagonism.
Topics: Acetic Acid; Analgesics; Animals; Benzomorphans; Binding, Competitive; Bridged-Ring Compounds; Cell Line, Tumor; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Hot Temperature; Ileum; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Morphinans; Narcotic Antagonists; Pain; Pain Measurement; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sulfur Radioisotopes; Vas Deferens | 2005 |
Effects of atypical kappa-opioid receptor agonists on intrathecal morphine-induced itch and analgesia in primates.
Topics: Analgesia; Animals; Benzomorphans; Female; Hot Temperature; Injections, Spinal; Macaca mulatta; Male; Morphinans; Morphine; Neurons; Piperazines; Pyrrolidines; Reaction Time; Receptors, Opioid, kappa; Restraint, Physical; Spiro Compounds | 2009 |