bremazocine and enkephalin, leucine-2-alanine

bremazocine has been researched along with enkephalin, leucine-2-alanine in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199026 (74.29)18.7374
1990's7 (20.00)18.2507
2000's2 (5.71)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kowalski, J; Petrillo, P; Sbacchi, M; Tavani, A1
Barnard, EA; Richardson, A; Simon, J1
Colombo, M; La Regina, A; Petrillo, P; Tavani, A1
Millan, MJ; Morris, BJ1
Dissanayake, VU; Hill, RG; Hughes, J; Hunter, JC1
Kobylyansky, AG; Nesterenko, PN; Pivovarov, AS; Yarygin, KN1
Kobylyansky, AG1
Kosterlitz, HW; La Regina, A; Petrillo, P; Robson, LE; Sbacchi, M; Tavani, A1
Hoffman, PL; Khatami, S; Salafsky, B; Shibuya, T1
La Regina, A; Petrillo, P; Sbacchi, M; Tavani, A1
Costa, T; Herz, A; Lang, J; Przewłocki, R1
Bolger, GT; Marcus, KA; Skolnick, P; Thibou, R; Weissman, BA1
Herz, A; Millan, MJ; Morris, BJ1
Bunn, SJ; Livett, BG; Marley, PD1
Ishihara, K; Iwama, T; Satoh, M; Takagi, H1
De Montis, GM; Devoto, P; Preti, A; Tagliamonte, A1
Ensinger, HA1
Boudouresque, F; Bourhim, N; Cantau, P; Castanas, E; Giraud, P; Oliver, C1
Burke, TR; Bykov, V; Danks, JA; Herkenham, M; Jacobson, AE; Rice, KC; Rothman, RB1
Herz, A; Morris, BJ1
Ignatov, IuD; Zaĭtsev, AA1
Bakalkin, GIa; Pivovarov, AS; Romanenko, OK1
Itzhak, Y; Simon, EJ1
Bakalkin, GIa; Bespalova, ZhD; Iakovleva, TV; Korobov, KP; Vinogradov, VA1
Rance, MJ; Traynor, JR1
Goodman, RR; Snyder, SH1
Burkard, WP; Flück, N; Müller, PM1
Burke, TR; Danks, JA; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB1
Gähwiler, BH; Maurer, R1
Foote, RW; Maurer, R1
Gambino, MC; Petrillo, P; Tavani, A1
Mamede Rosa, ML; Prado, WA1
Adams, DJ; Trequattrini, C1
Bandari, P; Chaturvedi, K; Chinen, N; Christoffers, KH; Dondio, G; Howells, RD; Jiang, X; Raveglia, LF; Ronzoni, S1
Bolling, SF; Bowden, K; Claycomb, WC; Kenyon, E; Kovach, MA; Neilan, CL; Traynor, JR1

Other Studies

35 other study(ies) available for bremazocine and enkephalin, leucine-2-alanine

ArticleYear
Characterization of opioid binding sites in rat spinal cord.
    Journal of receptor research, 1992, Volume: 12, Issue:1

    Topics: Animals; Benzomorphans; Binding Sites; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; In Vitro Techniques; Male; Rats; Receptors, Opioid; Spinal Cord

1992
Protection by opioid ligands against modification of the opioid receptor by a carbodiimide.
    Biochemical pharmacology, 1992, Apr-01, Volume: 43, Issue:7

    Topics: Animals; Benzeneacetamides; Benzomorphans; Binding Sites; Brain Chemistry; Carbodiimides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guanylyl Imidodiphosphate; Guinea Pigs; Pyrrolidines; Receptors, Opioid

1992
Binding capacities and affinities at mu-, delta- and kappa-opioid sites in membrane suspensions from guinea-pig brain regions.
    Journal of receptor research, 1992, Volume: 12, Issue:2

    Topics: Animals; Benzomorphans; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; In Vitro Techniques; Male; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

1992
Inability of an opioid antagonist lacking negative intrinsic activity to induce opioid receptor up-regulation in vivo.
    British journal of pharmacology, 1991, Volume: 102, Issue:4

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzomorphans; Binding, Competitive; Drinking; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Narcotic Antagonists; Pain; Pain Measurement; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Sensory Thresholds; Up-Regulation

1991
Characterization of kappa-opioid receptors in the guinea-pig ileum.
    European journal of pharmacology, 1990, Jun-21, Volume: 182, Issue:1

    Topics: Animals; Benzeneacetamides; Benzomorphans; Binding, Competitive; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle, Smooth; Naloxone; Pyrroles; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Thiophenes

1990
Lateralization of opioid receptors in turtle visual cortex.
    Brain research, 1989, Feb-20, Volume: 480, Issue:1-2

    Topics: Animals; Benzomorphans; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Evoked Potentials, Visual; Functional Laterality; Morphine; Naloxone; Receptors, Opioid; Turtles; Visual Cortex

1989
Opioids induce postural asymmetry in spinal rat: the side of the flexed limb depends upon the type of opioid agonist.
    Brain research, 1989, Feb-20, Volume: 480, Issue:1-2

    Topics: Animals; Benzomorphans; Decerebrate State; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Functional Laterality; Male; Muscles; Naloxone; Narcotics; Phenazocine; Posture; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord; Time Factors

1989
Regional variations in binding capacities at mu-, delta- and kappa-opioid sites in membrane suspensions from rabbit brain.
    European journal of pharmacology, 1989, Jul-18, Volume: 166, Issue:2

    Topics: Analgesics; Animals; Benzomorphans; Binding, Competitive; Body Weight; Brain Chemistry; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; In Vitro Techniques; Male; Membranes; Nerve Tissue Proteins; Rabbits; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

1989
Selective effects of ethanol on opiate receptor subtypes in brain.
    Neuropharmacology, 1987, Volume: 26, Issue:10

    Topics: Animals; Benzomorphans; Binding, Competitive; Brain Chemistry; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethanol; In Vitro Techniques; Limbic System; Male; Mice; Mice, Inbred C57BL; Narcotics; Oligopeptides; Receptors, Opioid

1987
Interaction of U-69,593 with mu-, alpha- and kappa-opioid binding sites and its analgesic and intestinal effects in rats.
    Life sciences, 1988, Volume: 42, Issue:3

    Topics: Animals; Benzeneacetamides; Benzomorphans; Binding Sites; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Gastrointestinal Motility; In Vitro Techniques; Male; Naloxone; Nociceptors; Pyrrolidines; Rats; Receptors, Opioid

1988
Pertussis toxin abolishes the antinociception mediated by opioid receptors in rat spinal cord.
    European journal of pharmacology, 1987, Nov-24, Volume: 144, Issue:1

    Topics: Adenosine Diphosphate; Analgesics; Animals; Benzomorphans; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Membranes; Nociceptors; Pertussis Toxin; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Ribose; Spinal Cord; Virulence Factors, Bordetella

1987
Enhancement of [3H]DAGO1 binding to rat brain by low concentrations of monovalent cations.
    Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:11

    Topics: Animals; Batrachotoxins; Benzomorphans; Brain Chemistry; Cations, Monovalent; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Guanine Nucleotides; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Naloxone; Rats; Receptors, Opioid; Temperature

1987
Antagonist-induced opioid receptor up-regulation. II. Regionally specific modulation of mu, delta and kappa binding sites in rat brain revealed by quantitative autoradiography.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:2

    Topics: Animals; Autoradiography; Benzomorphans; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Kinetics; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Substantia Nigra

1988
The distribution of opioid binding subtypes in the bovine adrenal medulla.
    Neuroscience, 1988, Volume: 27, Issue:3

    Topics: Adrenal Medulla; Animals; Benzomorphans; Cattle; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

1988
Different effects of dynorphin A on in vitro guinea pig hippocampal CA3 pyramidal cells with various degrees of paired-pulse facilitation.
    Neuroscience letters, 1986, Jan-16, Volume: 63, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Drug Interactions; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Morphine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Synaptic Transmission

1986
Differential effect of mu, delta, and kappa opioid agonists on adenylate cyclase activity.
    Journal of neuroscience research, 1987, Volume: 17, Issue:4

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclases; Analgesics; Animals; Benzeneacetamides; Benzomorphans; Corpus Striatum; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Male; Morphinans; Peptide Fragments; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid

1987
Differentiating aspects of opioid receptor binding by [3H](-) (1R,5R,9R,2''S)-5,9-dimethyl-2-tetrahydrofurfuryl-2'-hydroxy-6,7- benzomorphan hydrochloride ([3H]Mr 2034), a drug preferentially acting on kappa-receptors.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:1A

    Topics: Animals; Benzomorphans; Binding, Competitive; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; In Vitro Techniques; Kinetics; Male; Morphinans; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, kappa

1985
Interaction of opiates with opioid binding sites in the bovine adrenal medulla: II. Interaction with kappa sites.
    Journal of neurochemistry, 1985, Volume: 45, Issue:3

    Topics: Adrenal Medulla; Animals; Benzomorphans; Binding Sites; Calcium; Cattle; Cyclazocine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Ethylketocyclazocine; Ethylmaleimide; Etorphine; Guinea Pigs; Kinetics; Lithium; Manganese; Narcotics; Oligopeptides; Phospholipases A; Potassium; Receptors, Opioid; Receptors, Opioid, kappa; Sodium; Stereoisomerism

1985
Preparation of rat brain membranes highly enriched with opiate kappa binding sites using site-directed acylating agents: optimization of assay conditions.
    Neuropeptides, 1985, Volume: 6, Issue:6

    Topics: Alkylating Agents; Animals; Autoradiography; Benzomorphans; Brain; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; In Vitro Techniques; Membranes; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Sodium Chloride

1985
Autoradiographic localization in rat brain of kappa opiate binding sites labelled by [3H]bremazocine.
    Neuroscience, 1986, Volume: 19, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Autoradiography; Benzomorphans; Binding Sites; Binding, Competitive; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Morphinans; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa

1986
[The role of various opiate receptors in the regulation of the nociceptive reaction of the arterial pressure].
    Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 103, Issue:4

    Topics: Animals; Benzomorphans; Blood Pressure; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hemodynamics; Morphine; Nociceptors; Rats; Receptors, Opioid

1987
[Effect of the opiate antagonist naloxone on the electrical activity of identified neurons in the edible snail].
    Nauchnye doklady vysshei shkoly. Biologicheskie nauki, 1987, Issue:6

    Topics: Animals; Benzomorphans; beta-Endorphin; Drug Interactions; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Helix, Snails; Membrane Potentials; Morphine; Naloxone; Neurons; Receptors, Opioid

1987
A novel phencyclidine analog interacts selectively with mu opioid receptors.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:2

    Topics: Analgesia; Animals; Benzomorphans; Binding, Competitive; Cerebellum; Dihydromorphine; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Ileum; Male; Mice; Muscle Contraction; Naloxone; Phencyclidine; Rats; Receptors, Opioid; Receptors, Opioid, mu; Vas Deferens

1984
[Binding sites of opiates and endogenous opioids in the oocytes of the toad Bufo viridis].
    Biokhimiia (Moscow, Russia), 1984, Volume: 49, Issue:6

    Topics: Animals; Benzomorphans; Binding Sites; Bufonidae; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Female; In Vitro Techniques; Kinetics; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Oocytes; Rabbits; Receptors, Opioid; Vas Deferens

1984
Opiate binding in the rat spinal cord: evidence for mu and delta sites.
    Neuropeptides, 1984, Volume: 5, Issue:1-3

    Topics: Animals; Benzomorphans; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; In Vitro Techniques; Male; Narcotics; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord

1984
Kappa opiate receptors localized by autoradiography to deep layers of cerebral cortex: relation to sedative effects.
    Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:18

    Topics: Analgesics; Analgesics, Opioid; Animals; Autoradiography; Benzomorphans; Brain Stem; Cerebral Cortex; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Male; Morphine; Organ Specificity; Receptors, Opioid; Receptors, Opioid, kappa; Tritium

1982
Characteristics of 3H-tifluadom binding in guinea-pig brain membranes.
    Journal of receptor research, 1984, Volume: 4, Issue:1-6

    Topics: Animals; Benzodiazepines; Benzomorphans; Binding Sites; Brain; Cyclazocine; Dihydromorphine; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; In Vitro Techniques; Male; Morphine; Receptors, Opioid

1984
Tritiated-6-beta-fluoro-6-desoxy-oxymorphone: a highly selective ligand for the opiate mu receptor whose binding is characterized by low nonspecific binding.
    Neuropeptides, 1984, Volume: 4, Issue:4

    Topics: Animals; Benzomorphans; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Hydromorphone; Isothiocyanates; Kinetics; Oxymorphone; Rats; Receptors, Opioid; Receptors, Opioid, mu; Thiocyanates; Tomography, Emission-Computed

1984
Involvement of mu-receptors in the opioid-induced generation of bursting discharges in hippocampal pyramidal cells.
    Regulatory peptides, 1981, Volume: 2, Issue:2

    Topics: Animals; Benzomorphans; Culture Techniques; Cyclazocine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dose-Response Relationship, Drug; Electrophysiology; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Hippocampus; Membrane Potentials; Morphinans; Rats; Receptors, Opioid; Receptors, Opioid, mu

1981
Autoradiographic localization of opiate kappa-receptors in the guinea-pig brain.
    European journal of pharmacology, 1982, Nov-05, Volume: 85, Issue:1

    Topics: Animals; Autoradiography; Benzomorphans; Binding, Competitive; Brain; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Hypothalamus, Middle; Male; Receptors, Opioid; Receptors, Opioid, kappa

1982
Bremazocine induces antinociception, but prevents opioid-induced constipation and catatonia in rats and precipitates withdrawal in morphine-dependent rats.
    Life sciences, 1984, Aug-27, Volume: 35, Issue:9

    Topics: Analgesics; Animals; Benzomorphans; Catatonia; Constipation; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Gastrointestinal Motility; Humans; Male; Morphinans; Morphine; Naloxone; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders

1984
Antinociception induced by opioid or 5-HT agonists microinjected into the anterior pretectal nucleus of the rat.
    Brain research, 1997, May-16, Volume: 757, Issue:1

    Topics: Analgesics; Animals; Benzomorphans; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Microinjections; Pain; Phenazocine; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Serotonin Receptor Agonists

1997
Opioid receptor-mediated inhibition of omega-conotoxin GVIA-sensitive calcium channel currents in rat intracardiac neurons.
    Journal of neurophysiology, 1998, Volume: 79, Issue:2

    Topics: Acetylcholine; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Benzomorphans; Calcium; Calcium Channels; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Heart Conduction System; Ion Channel Gating; Ion Transport; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; omega-Conotoxin GVIA; Parasympathetic Nervous System; Patch-Clamp Techniques; Peptides; Pertussis Toxin; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Virulence Factors, Bordetella

1998
Pharmacological profiles of selective non-peptidic delta opioid receptor ligands.
    Brain research. Molecular brain research, 2000, Sep-15, Volume: 80, Issue:2

    Topics: Amino Acid Sequence; Analgesics; Analgesics, Opioid; Benzomorphans; Binding, Competitive; Cells, Cultured; Cloning, Molecular; Down-Regulation; Enkephalin, Leucine-2-Alanine; GTP-Binding Proteins; Heterocyclic Compounds, 4 or More Rings; Humans; Indoles; Isoquinolines; Kidney; Ligands; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Morphine; Mutagenesis, Site-Directed; Naloxone; Narcotic Antagonists; Quinolines; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, mu; Tritium

2000
An immortalized myocyte cell line, HL-1, expresses a functional delta -opioid receptor.
    Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:12

    Topics: Analgesics; Benzomorphans; Binding, Competitive; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Enkephalin, Leucine-2-Alanine; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Ligands; Myocardium; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Time Factors; Tumor Cells, Cultured

2000