br 100 has been researched along with oxotremorine in 4 studies
*Oxotremorine: A non-hydrolyzed muscarinic agonist used as a research tool. [MeSH]
*Oxotremorine: A non-hydrolyzed muscarinic agonist used as a research tool. [MeSH]
| Studies (br 100) | Trials (br 100) | Recent Studies (post-2010) (br 100) | Studies (oxotremorine) | Trials (oxotremorine) | Recent Studies (post-2010) (oxotremorine) |
|---|---|---|---|---|---|
| 8 | 0 | 2 | 1,930 | 6 | 99 |
| Protein | Taxonomy | br 100 (IC50) | oxotremorine (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.4 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 5 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 2.321 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 2.7261 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 2.7261 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 2.7261 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 8 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 2.7261 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 4.5012 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, D; Cadman, E; Carrera, GM; Chung, JY; Garvey, DS; May, PD; McKinney, MM; Shue, YK; Vella-Rountree, L; Wasicak, JT | 1 |
| Chidester, CG; Collins, RJ; Francis, JW; Heier, RF; Moon, MW; Morris, JK; Russell, RR; Sage, GP; Sethy, VH | 1 |
| Amstutz, R; Jenden, DJ; Karlén, B; Ringdahl, B; Roch, M | 1 |
| Kramss, RH; Mangano, RM; Trybulski, EJ; Zhang, J | 1 |
4 other study(ies) available for br 100 and oxotremorine
| Article | Year |
|---|---|
Synthesis and in vitro characterization of novel amino terminally modified oxotremorine derivatives for brain muscarinic receptors.
Topics: Animals; Cerebral Cortex; Corpus Striatum; Magnetic Resonance Spectroscopy; Male; Oxotremorine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1992 |
Cholinergic activity of acetylenic imidazoles and related compounds.
Topics: Acetylene; Animals; Brain; Imidazoles; Mice; Molecular Structure; Muscarinic Antagonists; Oxotremorine; Rats; Receptors, Muscarinic; Salivation; Structure-Activity Relationship; Tears; Tremor; X-Ray Diffraction | 1991 |
Stereoselectivity of muscarinic receptors in vivo and in vitro for oxotremorine analogues. N-[4-(tertiary amino)-2-butynyl]-5-methyl-2-pyrrolidones.
Topics: Abdominal Muscles; Animals; Atropine; Carbachol; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; Lethal Dose 50; Male; Mice; Muscle Contraction; Oxotremorine; Pyrrolidinones; Rana pipiens; Receptors, Muscarinic; Stereoisomerism; Tremor | 1985 |
The synthesis and biochemical pharmacology of enantiomerically pure methylated oxotremorine derivatives.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Guanylyl Imidodiphosphate; Male; Methylation; N-Methylscopolamine; Oxotremorine; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Scopolamine Derivatives; Stereoisomerism | 1993 |