Page last updated: 2024-09-05

boswellic acid and indomethacin

boswellic acid has been researched along with indomethacin in 4 studies

Compound Research Comparison

Studies
(boswellic acid)
Trials
(boswellic acid)
Recent Studies (post-2010)
(boswellic acid)
Studies
(indomethacin)
Trials
(indomethacin)
Recent Studies (post-2010) (indomethacin)
2271514729,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomyboswellic acid (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jauch, J; Noha, SM; Paul, M; Schuster, D; Seitz, S; Verhoff, M; Werz, O1
Chand, D; Gupta, OP; Sharma, N1
Johri, RK; Khajuria, A; Khajuria, RK; Qazi, GN; Singh, J; Singh, S; Taneja, SC1
Indu, H; Rasool, M; Sabina, EP1

Other Studies

4 other study(ies) available for boswellic acid and indomethacin

ArticleYear
Tetra- and pentacyclic triterpene acids from the ancient anti-inflammatory remedy frankincense as inhibitors of microsomal prostaglandin E(2) synthase-1.
    Journal of natural products, 2014, Jun-27, Volume: 77, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Boswellia; Characidae; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Inhibitory Concentration 50; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Molecular Structure; Pentacyclic Triterpenes; Prostaglandin Antagonists; Prostaglandin-E Synthases; Resins, Plant; Structure-Activity Relationship; Tetracycline; Triterpenes

2014
A sensitive and relevant model for evaluating anti-inflammatory activity-papaya latex-induced rat paw inflammation.
    Journal of pharmacological and toxicological methods, 1992, Volume: 28, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease Models, Animal; Ibuprofen; Indomethacin; Inflammation; Levamisole; Male; Papain; Piroxicam; Prednisolone; Rats; Triterpenes

1992
The gastric ulcer protective effect of boswellic acids, a leukotriene inhibitor from Boswellia serrata, in rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2008, Volume: 15, Issue:6-7

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Boswellia; Ethanol; Hot Temperature; Hydrochloric Acid; Indomethacin; Leukotriene Antagonists; Ligation; Male; Phytotherapy; Rats; Rats, Wistar; Stomach Ulcer; Triterpenes

2008
Efficacy of boswellic acid on lysosomal acid hydrolases, lipid peroxidation and anti-oxidant status in gouty arthritic mice.
    Asian Pacific journal of tropical biomedicine, 2012, Volume: 2, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arthritis, Gouty; Female; Glucuronidase; Hydrolases; Indomethacin; Inflammation; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Mice; Neutrophils; Triterpenes; Tumor Necrosis Factor-alpha; Uric Acid

2012