Page last updated: 2024-09-05

boswellic acid and 11-keto-boswellic acid

boswellic acid has been researched along with 11-keto-boswellic acid in 13 studies

Compound Research Comparison

Studies
(boswellic acid)
Trials
(boswellic acid)
Recent Studies (post-2010)
(boswellic acid)
Studies
(11-keto-boswellic acid)
Trials
(11-keto-boswellic acid)
Recent Studies (post-2010) (11-keto-boswellic acid)
2271514716010
60516010

Protein Interaction Comparison

ProteinTaxonomyboswellic acid (IC50)11-keto-boswellic acid (IC50)
Prostaglandin E synthaseHomo sapiens (human)6.5
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)3
Tyrosine-protein phosphatase non-receptor type 2Homo sapiens (human)9.45
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)8.04

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (30.77)29.6817
2010's8 (61.54)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Choudhary, MI; Fatima, N; Kimbu, SF; Makhmoor, T; Naz, H; Ngounou, FN; Sondengam, BL; Yasin, A1
Khajuria, A; Khajuria, RK; Qazi, GN; Singh, J; Singh, S; Taneja, SC1
Gupta, P; Kumar, A; Qazi, GN; Saxena, AK; Sethi, VK; Shah, BA; Sharma, M; Singh, J; Taneja, SC1
Hong, D; Hu, LH; Li, J; Li, JY; Shen, Q; Shi, L; Zhang, W; Zhang, YN1
Chib, R; Kaur, R; Kaur, T; Khan, S; Shah, BA; Sharma, PR; Singh, J; Taneja, SC1
Hamid, A; Kumar, A; Saxena, AK; Sethi, VK; Shah, BA; Singh, J; Singh, S; Singh, SK; Taneja, SC1
Abdel-Tawab, M; Fricker, G; Gerbeth, K; Hüsch, J; Rebmann, H; Schubert-Zsilavecz, M; Setzer, C; Zirkel, J1
Jauch, J; Noha, SM; Paul, M; Schuster, D; Seitz, S; Verhoff, M; Werz, O1
Diwakar, L; Kiran, KR; Kumar, K; Reddy, GC; Shenvi, S1
Ahmed, Z; Bhagat, A; Gupta, S; Khajuria, V; Shah, BA; Sharma, S1
Atanasov, AG; Kamal, MA; Khan, H; Nabavi, SM; Pervaiz, A; Rengasamy, KRR1
Fukushima, EO; Muranaka, T; Nomura, Y; Vo, NNQ1
Gou, W; Guo, J; Hou, W; Li, Y; Liu, Q; Ning, H; Shang, H; Sun, X; Wei, H1

Reviews

2 review(s) available for boswellic acid and 11-keto-boswellic acid

ArticleYear
Plant-derived mPGES-1 inhibitors or suppressors: A new emerging trend in the search for small molecules to combat inflammation.
    European journal of medicinal chemistry, 2018, Jun-10, Volume: 153

    Topics: Animals; Anti-Inflammatory Agents; Biological Products; Drug Discovery; Enzyme Inhibitors; Humans; Inflammation; Plants, Medicinal; Prostaglandin-E Synthases

2018
Discovery of Natural Ursane-type SENP1 Inhibitors and the Platinum Resistance Reversal Activity Against Human Ovarian Cancer Cells: A Structure-Activity Relationship Study.
    Journal of natural products, 2022, 05-27, Volume: 85, Issue:5

    Topics: Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cisplatin; Cysteine Endopeptidases; Drug Resistance, Neoplasm; Female; Humans; Molecular Docking Simulation; Ovarian Neoplasms; Structure-Activity Relationship; Triterpenes

2022

Other Studies

11 other study(ies) available for boswellic acid and 11-keto-boswellic acid

ArticleYear
Bioactive constituents from Boswellia papyrifera.
    Journal of natural products, 2005, Volume: 68, Issue:2

    Topics: Boswellia; Cameroon; Enzyme Inhibitors; Glycosides; Inhibitory Concentration 50; Molecular Structure; Plants, Medicinal; Stilbenes; Triterpenes

2005
Boswellic acids and glucosamine show synergistic effect in preclinical anti-inflammatory study in rats.
    Bioorganic & medicinal chemistry letters, 2007, Jul-01, Volume: 17, Issue:13

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Carrageenan; Chemistry, Pharmaceutical; Drug Design; Drug Evaluation, Preclinical; Drug Synergism; Edema; Glucosamine; Magnetic Resonance Spectroscopy; Models, Chemical; Mycobacterium; Rats; Triterpenes

2007
Cytotoxic and apoptotic activities of novel amino analogues of boswellic acids.
    Bioorganic & medicinal chemistry letters, 2007, Dec-01, Volume: 17, Issue:23

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Boswellia; Cell Line, Tumor; DNA Fragmentation; Growth Inhibitors; Humans; Triterpenes

2007
Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities.
    Bioorganic & medicinal chemistry, 2008, Sep-15, Volume: 16, Issue:18

    Topics: Animals; Cell Line; CHO Cells; Cricetinae; Cricetulus; Diabetes Mellitus; Drugs, Chinese Herbal; Enzyme Inhibitors; Humans; Insulin; Obesity; Oleanolic Acid; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptor, Insulin; Structure-Activity Relationship; T-Lymphocytes

2008
A comparative study of proapoptotic potential of cyano analogues of boswellic acid and 11-keto-boswellic acid.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; HeLa Cells; HL-60 Cells; Humans; Nitriles; Oxygen; Triterpenes

2011
Acyl derivatives of boswellic acids as inhibitors of NF-κB and STATs.
    Bioorganic & medicinal chemistry letters, 2012, Jan-01, Volume: 22, Issue:1

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Flow Cytometry; HL-60 Cells; Humans; Models, Chemical; NF-kappa B; Phosphorylation; STAT Transcription Factors; Triterpenes

2012
Effect of phospholipid-based formulations of Boswellia serrata extract on the solubility, permeability, and absorption of the individual boswellic acid constituents present.
    Journal of natural products, 2012, Oct-26, Volume: 75, Issue:10

    Topics: Absorption; Administration, Oral; Animals; Boswellia; Brain; Caco-2 Cells; Humans; Male; Models, Biological; Permeability; Phospholipids; Poloxamer; Polysorbates; Rats; Solubility; Time Factors; Triterpenes; Vitamin E

2012
Tetra- and pentacyclic triterpene acids from the ancient anti-inflammatory remedy frankincense as inhibitors of microsomal prostaglandin E(2) synthase-1.
    Journal of natural products, 2014, Jun-27, Volume: 77, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Boswellia; Characidae; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Inhibitory Concentration 50; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Molecular Structure; Pentacyclic Triterpenes; Prostaglandin Antagonists; Prostaglandin-E Synthases; Resins, Plant; Structure-Activity Relationship; Tetracycline; Triterpenes

2014
Synthesis and biological evaluation of boswellic acid-NSAID hybrid molecules as anti-inflammatory and anti-arthritic agents.
    European journal of medicinal chemistry, 2015, Jun-15, Volume: 98

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Rats; Rats, Wistar; Triterpenes

2015
Analogues of boswellic acids as inhibitors of pro-inflammatory cytokines TNF-α and IL-6.
    Bioorganic & medicinal chemistry letters, 2016, Jan-15, Volume: 26, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Humans; Interleukin-6; Mice; Triterpenes; Tumor Necrosis Factor-alpha

2016
Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes.
    Journal of natural products, 2019, 12-27, Volume: 82, Issue:12

    Topics: Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Humans; Lipoxygenase Inhibitors; Pentacyclic Triterpenes; Structure-Activity Relationship

2019