bosentan anhydrous has been researched along with mibefradil in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (46.15) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coassolo, P; Lavé, T; Schneider, G | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Clozel, JP; Clozel, M; Gonzales, MF; Hess, P; Heudes, D; Karam, H; Löffler, BM | 1 |
| Bruneval, P; Clozel, JP; Clozel, M; Gonzales, MF; Heudes, D; Karam, H; Löffler, BM | 1 |
| Fenger-Grøn, J; Mulvany, MJ; Skov, K | 1 |
| Keil, U | 1 |
| Clozel, JP; Clozel, M; Gonzales, MF; Heudes, D; Karam, H; Löffler, BM | 1 |
| Poole-Wilson, PA; van Veldhuisen, DJ | 1 |
2 review(s) available for bosentan anhydrous and mibefradil
| Article | Year |
|---|---|
Effects of an angiotensin-converting enzyme inhibitor, a calcium antagonist, and an endothelin receptor antagonist on renal afferent arteriolar structure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Benzimidazoles; Blood Pressure; Bosentan; Calcium Channel Blockers; Cilazapril; Endothelin Receptor Antagonists; Kidney; Male; Mibefradil; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Sulfonamides; Tetrahydronaphthalenes | 1996 |
The underreporting of results and possible mechanisms of 'negative' drug trials in patients with chronic heart failure.
Topics: Bosentan; Cardiovascular Agents; Deoxyepinephrine; Heart Failure; Humans; Imidazoles; Mibefradil; Pyrazines; Quinolines; Sulfonamides; Xamoterol | 2001 |
11 other study(ies) available for bosentan anhydrous and mibefradil
| Article | Year |
|---|---|
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats | 1999 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Respective role of humoral factors and blood pressure in cardiac remodeling of DOCA hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Bosentan; Calcium Channel Blockers; Cardiomegaly; Collagen; Coronary Circulation; Desoxycorticosterone; Enalapril; Endothelin Receptor Antagonists; Fibrosis; Hypertension; Male; Mibefradil; Myocardium; Perfusion; Rats; Rats, Wistar; Sulfonamides; Tetrahydronaphthalenes | 1996 |
Endothelin antagonism in end-organ damage of spontaneously hypertensive rats. Comparison with angiotensin-converting enzyme inhibition and calcium antagonism.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Benzimidazoles; Body Weight; Bosentan; Calcium Channel Blockers; Cardiomegaly; Coronary Circulation; Enalapril; Endothelins; Fibrosis; Heart Ventricles; Hemodynamics; Hormones; Hypertension; Kidney; Mibefradil; Myocardium; Rats; Rats, Inbred SHR; Sulfonamides; Tetrahydronaphthalenes | 1996 |
[Progress in new cardiovascular treatment. Background discussion and interview in the Basel Roche Research Center].
Topics: Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Bosentan; Calcium Channel Blockers; Cardiovascular Diseases; Cilazapril; Endothelins; Hemodynamics; Humans; Mibefradil; Sulfonamides; Tetrahydronaphthalenes | 1996 |
Respective role of humoral factors and blood pressure in aortic remodeling of DOCA hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Benzimidazoles; Blood Pressure; Bosentan; Calcium Channel Blockers; Desoxycorticosterone; Enalapril; Endothelin Receptor Antagonists; Endothelins; Hypertension, Renovascular; Male; Mibefradil; Rats; Rats, Wistar; Sulfonamides; Tetrahydronaphthalenes; Tunica Media | 1996 |