boron and boron-nitride

The current status of research on boron-carbon-nitrogen (B-C-N) and boron nitride (BN) nanotubes is presented. The latest achievements in syntheses, analyses and property measurements of these nanoscale tubular architectures are reviewed. The characteristic features of B-C-N and BN nanotubes, compared with conventional C nanotubes, are paid special attention. In particular, the latest breakthroughs in the chemical vapour deposition synthesis of BN nanotubes and an insight into their unique structures are highlighted. A wide range of potential applications is also envisaged, based on the recent progress, which includes pioneering results in BN nanocable fabrication, gas adsorption, electron transport and field emission measurements.

Topics: Biocompatible Materials; Boron; Boron Compounds; Carbon; Crystallization; Electrochemistry; Equipment Design; Macromolecular Substances; Molecular Conformation; Nanotechnology; Nanotubes; Nanotubes, Carbon; Nitrogen

In this study, computational simulations were used to investigate the performance of a carbon-doped boron nitride nanoribbon (BC2NNR) for hydrogen (H2) gas sensing at elevated temperatures. The adsorption energy and charge transfer were calculated when H2 was simultaneously attached to carbon, boron, and both boron and nitrogen atoms. The sensing ability was further analyzed considering the variations in current-voltage (I-V) characteristics. The simulation results indicated that the energy bandgap of H2 on carbon, boron, and both boron and nitrogen exhibited a marginal effect during temperature variations. However, significant differences were observed in terms of adsorption energy at a temperature of 500 K, wherein the adsorption energy was increased by 99.62% of that observed at 298 K. Additionally, the evaluation of charge transfer indicated that the strongest binding site was achieved at high adsorption energies with high charge transfers. Analysis of the I-V characteristics verified that the currents were considerably affected, particularly when a certain concentration of H2 molecules was added at the highest sensitivity of 15.02% with a bias voltage of 3 V. The sensitivity at 298 K was lower than those observed at 500 and 1000 K. The study findings can form the basis for further experimental investigations on BC2NNR as a hydrogen sensor.

Topics: Boron; Hydrogen; Nanotubes, Carbon; Nitrogen; Temperature

In this research, the thermoelectric properties of the (6, 6) two sided-closed single-walled boron nitride nanotube ((6, 6) TSC-SWBNNT) was investigated in the state without impurity and carbon atom impurity instead of boron and nitrogen atoms in the center, left, and right the nanotube. The test conditions were the energy range of -5.5 to 5.5 eV and temperatures of 200, 300, 500, 700, 900, 1100, and 1300 K. Based on the obtained results, with an increase in temperature and the creation of impurities, the band gap is affected and becomes noticeably smaller. At the temperature of 1300 K, the band gap shows the greatest decrease and the peak height shows the least decrease. With increasing temperature, the number of peaks has decreased, suggesting an increase in the mobility of electrons and holes and a decrease in their localization. The Seebeck coefficient figures also changed by replacing carbon atoms with boron and nitrogen atoms in different parts of the nanotube. In addition, the height of the heat conduction peaks increased with increasing temperature. However, the heat conduction values are generally in the range of 9-10 nm, which are small values. With the increase in temperature, ZT values increased such that the highest values corresponded to the temperature of 1300 K. The ZT values higher than 1, especially at high temperatures, show that (6, 6) TSC-SWBNNT nanotubes are suitable candidates for thermoelectric materials.

Topics: Boron; Carbon; Nanotubes; Temperature

Heterostructures may exhibit completely new physical properties that may be otherwise absent in their individual component materials. However, how to precisely grow or assemble desired complex heterostructures is still a significant challenge. In this work, the collision dynamics of a carbon nanotube and a boron nitride nanotube under different collision modes were investigated using the self-consistent-charge density-functional tight-binding molecular dynamics method. The energetic stability and electronic structures of the heterostructure after collision were calculated using the first-principles calculations. Five main collision outcomes are observed, that is, two nanotubes can (1) bounce back, (2) connect, (3) fuse into a defect-free BCN heteronanotube with a larger diameter, (4) form a heteronanoribbon of graphene and hexagonal boron nitride and (5) create serious damage after collision. It was found that both the BCN single-wall nanotube and the heteronanoribbon created by collision are the direct band-gap semiconductors with the band gaps of 0.808 eV and 0.544 eV, respectively. These results indicate that collision fusion is a viable method to create various complex heterostructures with new physical properties.

Topics: Boron; Boron Compounds; Molecular Dynamics Simulation; Nanotubes, Carbon

The treatment process of osteoarthritis (OA) is challenging as it affects not only cartilage but also subchondral bone, ligament attachment capsules, synovium, and surrounding muscle tissue. Therefore, the search for preventive treatment or methods to slow the onset of the condition. Hexagonal boron nitride (hBN) has a graphite-like lamellar structure and is thought to facilitate cartilage movement for biomedical applications, just like in bearing systems. Hyaluronic acid (HA) is one of the natural polymers that can be used to transport boron nitride and maintain its presence in joints for a long time. In this study, hybrid hydrogels were formulated by using boron nitride nanoparticles and nanosheets. The rheological properties of the hydrogels were evaluated according to the structural differences of hBN. Characterizations have shown that hybrid hydrogels can be produced in injectable form, and the rheological properties are strongly related to the structural properties of the added particle. It has been determined that hBN added to the hydrogel structure reduces the dynamic viscosity of the zero-shear point and the deformation rate of the hydrogel and also changes the viscoelastic properties of the hydrogel depending on boron nitride's structural differences. The suggested mechanism is the hybrid hydrogel that exhibits lower viscosity as the layers detach from each other or disperses the agglomerates under applied shear stress. hBN, which has been proposed as a new strategy for joint injections, is thought to be a promising candidate for the treatment of OA due to its lamellar structures.

Topics: Boron; Hyaluronic Acid; Hydrogels; Synovial Fluid

The boron-based ceramics namely hexagonal boron nitride (h-BN) and boron phosphate (BPO4) were synthesized and characterized by Fourier transform infrared spectroscopy and X-ray diffraction analysis. The surface properties of h-BN and BPO4 were examined by inverse gas chromatography method. The dispersive surface energy and the acidic-basic character of h-BN, and BPO4 surfaces were estimated by the retention time with probes such as n-hexane, n-heptane, n-octane, n-nonane, n-decane, acetone, ethyl acetate, dichloromethane, chloroform and tetrahydrofuran at infinite dilution region. The dispersive surface free energies calculated using both Schultz and Dorris-Gray methods, decreased linearly with increasing temperature. The specific adsorption free energy and the specific adsorption enthalpy corresponding to acid-base surface interactions were determined. By correlating with the donor and acceptor numbers of the probes, the acidic and the basic parameters of the h-BN and BPO4 were calculated. The values obtained for and parameters indicated that h-BN has a basic character, whereas BPO4 has an acidic character.

Topics: Boron; Chromatography, Gas; Phosphates; Surface Properties

Titanium dental implants has been coated with different materials such as polymers and biomimetic agents, bone morphogenetic protein, calcium phosphate to enhance surface properties of the titanium implants for osseointegration. The aim of this study was to evaluate the bone tissue healing around Boron Nitride-coated (BN-coated) titanium implants histomorphometrically and biomechanically and also observe the effect of different coating thicknesses on osseointegration.. BN was coated on dental titanium implants with two different coating thicknesses by using RF magnetron sputtering system. Totally fifty-four implants were inserted into the tibias' of 12 New Zealand rabbits bilaterally under general anesthesia. All animals were sacrificed after 4-weeks. Bone-implant contact (BIC) and new bone area/total area ratios (BATA) were calculated. Also, the removal torque (RT) test was performed.. The highest new bone area in the medullary cavity was around the nano-BN-coated surface with 15.70%. In micro-BN-coated surface and control group, this ratio was determined as 10.48% and 8.23%, respectively. The BIC ratios in upper-side of implants and cortical-associated BIC ratios in lower-side were found significantly higher in control and micro-BN-coated group than nano-BN-coated group (p < 0.05). Similar BIC values were observed between control and micro-BN-coated groups (p > 0.05). BATA values did not show statistically significant differences between all three groups (p > 0.05). The RT values measured in all groups were found comparable and no statistically significant differences were found (p > 0.05).. No inflammatory reaction developed around any implant. Relatively more new bone formation around nano-BN-coated titanium implants indicates the promising osseoinductive effect of BN coating. BN-coated implants showed similar biomechanical and histomorphometrical outcomes to that of the conventional titanium implants through a 4-week evaluation period.

Topics: Animals; Boron; Coated Materials, Biocompatible; Dental Implants; Humans; Osseointegration; Rabbits; Titanium

The search for an innovative and effective drug delivery system that can carry and release targeted drugs with enhanced activity to treat Alzheimer's disease has received much attention in the last decade. In this study, we first designed a boron-based drug delivery system for effective treatment of AD by integrating the folic acid (FA) functional group into hexagonal boron nitride (hBN) nanoparticles (NPs) through an esterification reaction. The hBN-FA drug carrier system was assembled with a new drug candidate and a novel boron-based hybrid containing an antioxidant as BLA, to constitute a self-assembled AD nano transport system. We performed molecular characterization analyses by using UV-vis spectroscopy, Fourier transform infrared spectrophotometer (FTIR), scanning electron microscope (SEM), Energy-dispersive X-ray spectroscopy (EDS) and Zeta potential investigations. Second, we tested the anti-Alzheimer properties of the carrier system on a differentiated neuroblastoma (SHSY5-Y) cell line, which was exposed to beta-amyloid (1-42) peptides to stimulate an experimental in vitro AD model. Next, we performed cytotoxicity analyses of synthesized molecules on the human dermal fibroblast cell line (HDFa) and the experimental AD model. Cytotoxicity analyses showed that even higher concentrations of the carrier system did not enhance the toxicological outcome in HDFa cells. Drug loading analyses reported that uncoated hBN nano conjugate could not load the BLA, whereas the memantine loading capacity of hBN was 84.3%. On the other hand, memantine and the BLA loading capacity of the hBN-FA construct was found to be 95% and 97.5%, respectively. Finally, we investigated the neuroprotective properties of the nano carrier systems in the experimental AD model. According to the results, 25 µg/mL concentrations of hBN-FA+memantine (94% cell viability) and hBN-FA+BLA (99% cell viability) showed ameliorative properties against beta-amyloid (1-42) peptide toxicity (50% cell viability). These results were generated through the use of flow cytometry, acetylcholinesterase (AChE) and antioxidant assays. In conclusion, the developed drug carrier system for AD treatment showed promising potential for further investigations and enlightened neuroprotective capabilities of boron molecules to treat AD and other neurodegenerative diseases. On the other hand, enzyme activity, systematic toxicity analyses, and animal studies should be performed to understand neuroprotective propertie

Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Boron; Boron Compounds; Drug Carriers; Folic Acid; Humans; Memantine; Nanoparticles

The interaction of α-glucose with a BN-nanosheet, BN-nanotube, and BN-fullerene, was analyzed from an atomistic and electronic point of view, to evaluate such nanostructures as possible carriers and/or biosensors of the α-glucose molecule. Adsorption energies are in the range of physisorption (-0.79 eV to -0.91 eV) for the BN-nanosheet and -nanotube, and chemisorption (-2.24 eV to -2.35 eV), for the BN-fullerene. All systems, exhibit semiconductor-like behavior and great stability according to |LUMO-HOMO| energy gap [Gap

Topics: Biosensing Techniques; Boron; Electronics; Fullerenes; Glucose; Nanostructures

Topics: Adsorption; Anti-Bacterial Agents; Boron; Boron Compounds; Porosity

The shortcomings in Boron neutron capture therapy (BNCT) and Hyperthermia for killing the tumor cell desired for the synthesis of a new kind of material suitable to be first used in BNCT and later on enable the conditions for Hyperthermia to destroy the tumor cell. The desire led to the synthesis of large band gap semiconductor nano-size Boron-10 enriched crystals of hexagonal boron nitride (

Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Humans; Hyperthermia, Induced; Isotopes; Microscopy, Electron, Transmission; Nanoparticles; Nanotechnology; Neoplasms; Photoelectron Spectroscopy; Quantum Dots; Spectrum Analysis, Raman; X-Ray Diffraction

Defect engineering potentially allows for dramatic tuning of the optoelectronic properties of two-dimensional materials. With the help of DFT calculations, a systematic study of DNA nucleobases adsorbed on hexagonal boron-nitride nanoflakes (h-BNNFs) with boron (V

Topics: Adsorption; Biosensing Techniques; Boron; Boron Compounds; DNA; Electricity; Nanostructures; Nitrogen; Optical Devices; Quantum Theory

High global incidence of prostate cancer has led to a focus on prevention and treatment strategies to reduce the impact of this disease in public health. Boron compounds are increasingly recognized as preventative and chemotherapeutic agents. However, systemic administration of soluble boron compounds is hampered by their short half-life and low effectiveness. Here we report on hollow boron nitride (BN) spheres with controlled crystallinity and boron release that decrease cell viability and increase prostate cancer cell apoptosis. In vivo experiments on subcutaneous tumour mouse models treated with BN spheres demonstrated significant suppression of tumour growth. An orthotopic tumour growth model was also utilized and further confirmed the in vivo anti-cancer efficacy of BN spheres. Moreover, the administration of hollow BN spheres with paclitaxel leads to synergetic effects in the suppression of tumour growth. The work demonstrates that hollow BN spheres may function as a new agent for prostate cancer treatment.

Topics: Alarmins; Animals; Antineoplastic Agents; Apoptosis; Biomarkers; Boron; Boron Compounds; Cell Line, Tumor; Cell Shape; Chemical Phenomena; Humans; Injections, Subcutaneous; Male; Mice, Inbred BALB C; Mice, Nude; Nanospheres; Necrosis; Prostatic Neoplasms; Tissue Distribution; Xenograft Model Antitumor Assays

Boron and its derivatives are effective in bone recovery and osteointegration. However, increasing the boron levels in body liquids may cause toxicity. The aim of our study is to investigate serum boron levels using ICP-MS after implantation of different ratios of nano-hBN-HA composites in rat femurs. All rats were (n=126) divided into five experimental groups (n=24) and one healthy group (6 rats); healthy (Group1), femoral defect + %100 HA (Group2), femoral defect + %2.5 hBN + %97.5 HA (Group3), femoral defect + %5 hBN + %95 HA (Group4), femoral defect + %10 hBN + %90 HA (Group5), femoral defect + %100 hBN (Group6). The femoral defect was created in the distal femur (3mm drill-bit). Each implant group was divided into four different groups (n=24) also 6 rats sacrificed for each groups in one week intervals during four weeks. In our results; at 1, 2, 3, and 4 weeks after implantation near bone tissue, serum levels of boron were evaluated using ICP-MS. We demonstrated that neither short-term nor long-term implantation of hBN-HA composite resulted in statistically increased serum boron levels in experimental groups compared to healthy group. In conclusion, this study investigated the implant material produced form hBN-HA for the first time. Our data suggest that hBN is a new promising target for biomaterial and implant bioengineers.

Topics: Animals; Apatites; Biocompatible Materials; Boron; Boron Compounds; Femur; Nanocomposites; Rats; Rats, Sprague-Dawley

We demonstrate the use of thin BN sheets as supports for imaging nanocrystals using low voltage (80 kV) aberration-corrected high resolution transmission electron microscopy. This provides an alternative to the previously utilized 2D crystal supports of graphene and graphene oxide. A simple chemical exfoliation method is applied to get few layer boron nitride (BN) sheets with micrometer-sized dimensions. This generic approach of using BN sheets as supports is shown by depositing Mn doped ZnSe nanocrystals directly onto the BN sheets and resolving the atomic structure from both the ZnSe nanocrystals and the BN support. Phase contrast images reveal moiré patterns of interference between the beams diffracted by the nanocrystals and the BN substrate that are used to determine the relative orientation of the nanocrystals with respect to the BN sheets and interference lattice planes. Double diffraction is observed and has been analyzed.

Topics: Boron; Boron Compounds; Crystallization; Graphite; Manganese; Materials Testing; Microscopy, Electron, Transmission; Models, Statistical; Nanoparticles; Nanotechnology; Nitrogen; Oxides; Selenium; Selenium Compounds; Zinc; Zinc Compounds

We have carried out an isotope study on the band gap and radiative transition spectra of boron nitride nanotubes (BNNTs) using both experimental and theoretical approaches. The direct band gap of BNNTs was determined at 5.38 eV, independent of the nanotube size and isotope substitution, by cathodoluminescences (CL) spectra. At lower energies, several radiative transitions were observed, and an isotope effect was revealed. In particular, we confirmed that the rich CL spectra between 3.0 and 4.2 eV reflect a phonon-electron coupling mechanism, which is characterized by a radiative transition at 4.09 eV. The frequency red shift and peak broadening due to isotopic effect have been observed. Our Fourier transform infrared spectra and density functional theory calculations suggest that those radiative transitions in BNNTs could be generated by a replacement of some nitrogen atoms with oxygen.

Topics: Boron; Boron Compounds; Computer Simulation; Crystallization; Isotopes; Macromolecular Substances; Materials Testing; Models, Chemical; Models, Molecular; Molecular Conformation; Nanostructures; Nanotechnology; Particle Size; Surface Properties

Bonding analysis is performed on alternant B(16)N(16) cage based on a combined study of DFT with NBO method. The main feature of such analysis is the separation of bonding structure into two components: sigma skeleton and pi bond system. Each component is further decomposed into contributions from various NBOs, thus we obtain the details of bonding interactions of every BN unit. Based on these results, relative stability of four covalent dimers of B(16)N(16) is predicted and this prediction is verified by DFT calculations. So the possibility of forecasting properties of oligomers just from analysis on monomer is highlighted in this way.

Topics: Boron; Boron Compounds; Dimerization; Models, Chemical; Models, Molecular; Nitrogen