boromycin and nojirimycin

boromycin has been researched along with nojirimycin* in 1 studies

Other Studies

1 other study(ies) available for boromycin and nojirimycin

Article	Year
Boromycin, an anti-HIV antibiotic. Bioscience, biotechnology, and biochemistry, 1996, Volume: 60, Issue:6 The polyether-macrolide antibiotic, boromycin, was isolated as a potent anti-human immunodeficiency virus (HIV) antibiotic from a fermentation broth of Streptomyces sp. A-3376. Boromycin was found to strongly inhibit the replication of the clinically isolated HIV-1 strain as well as the cultured strain in in vitro laboratory experiments. The mechanism for the anti-HIV activity of boromycin is suggested to involve blocking the later stage of HIV infection, and probably the maturity step for replication of the HIV molecule. Topics: 1-Deoxynojirimycin; Anti-Bacterial Agents; Antiviral Agents; Borates; Cell Line; Dextran Sulfate; Glucosamine; Glycoside Hydrolases; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Molecular Structure; RNA-Directed DNA Polymerase; Streptomyces	1996

Article

Year

Bioscience, biotechnology, and biochemistry, 1996, Volume: 60, Issue:6

The polyether-macrolide antibiotic, boromycin, was isolated as a potent anti-human immunodeficiency virus (HIV) antibiotic from a fermentation broth of Streptomyces sp. A-3376. Boromycin was found to strongly inhibit the replication of the clinically isolated HIV-1 strain as well as the cultured strain in in vitro laboratory experiments. The mechanism for the anti-HIV activity of boromycin is suggested to involve blocking the later stage of HIV infection, and probably the maturity step for replication of the HIV molecule.

Topics: 1-Deoxynojirimycin; Anti-Bacterial Agents; Antiviral Agents; Borates; Cell Line; Dextran Sulfate; Glucosamine; Glycoside Hydrolases; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Molecular Structure; RNA-Directed DNA Polymerase; Streptomyces

1996