bongkrekic-acid has been researched along with pifithrin* in 1 studies
1 other study(ies) available for bongkrekic-acid and pifithrin
Article | Year |
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Apoptotic mitochondrial dysfunction induced by benzo(a)pyrene in liver epithelial cells: role of p53 and pHi changes.
How pH(i) changes, more specifically alkalinization, affect the apoptotic cascade has yet to be determined. The aim of the present work was to test the involvement of mitochondria in the apoptotic cascade triggered by benzo(a)pyrene [B(a)P] and to determine the role of pH(i) changes and p53 relative to mitochondria. Our results indicate that B(a)P-induced apoptosis might rely upon a p53-dependent and a pH-sensitive mitochondrial dysfunction. Topics: Animals; Apoptosis; Benzo(a)pyrene; Benzothiazoles; Bongkrekic Acid; Cell Line; Epithelial Cells; Guanidines; Hydrogen-Ion Concentration; Liver; Mitochondria; Rats; Sulfones; Thiazoles; Toluene; Tumor Suppressor Protein p53 | 2003 |