bohemine and olomoucine

bohemine has been researched along with olomoucine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (83.33)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Havlícek, L; Koca, J; Krystof, V; Otyepka, M; Siglerová, V; Strnad, M1
Havlícek, L; Krystof, V; Kuzma, M; Lenobel, R; Strnad, M1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Bravo-Altamirano, K; DeStefino, NR; Liang, M; Mazzarisi, CM; Meriney, SD; Olszewski, RA; Rensch, G; Swanson, L; Tarr, TB; Valdomir, G; Wilson, GM; Wipf, P1
Gouldsworthy, A; Hajdúch, M; Halada, P; Korínková, G; Kovárová, H; Krupicková, S; Strnad, M; Zhelev, N1
Hajdúch, M; Hlobilková, A; Kolár, Z; Lenobel, R; Lukesová, M; Mad'arová, J; Murray, PG; Perera, S; Strnad, M; Vojtesek, B1
Bartos, J; Kylarová, D; Lichnovský, V; Mad'arová, J; Procházková, J1
Dolezal, K; Malon, M; Marek, J; Strnad, M; Trávnícek, Z; Zatloukal, M1
Barrie, SE; Brunton, L; Clarke, SJ; Eccles, S; Fischer, PM; Garrett, MD; Kelland, LR; Lane, DP; McClue, S; Raynaud, FI; Rogers, P; Valenti, M; Walton, MI; Whittaker, SR; Workman, P1
Krystof, V; Sipl, M; Trávnícek, Z1
An, R; Hagiya, Y; Ishikawa, T; Li, S; Saito, H; Tamura, A; Tokushima, D1
Cwiertka, K; Dzubak, P; Hajduch, M; Korinkova, G; Paprskarova, M1

Other Studies

12 other study(ies) available for bohemine and olomoucine

ArticleYear
Docking-based development of purine-like inhibitors of cyclin-dependent kinase-2.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Catalytic Domain; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Drug Design; Enzyme Inhibitors; Ligands; Models, Molecular; Molecular Conformation; Protein Serine-Threonine Kinases; Purines; Structure-Activity Relationship

2000
Synthesis and biological activity of olomoucine II.
    Bioorganic & medicinal chemistry letters, 2002, Nov-18, Volume: 12, Issue:22

    Topics: Antineoplastic Agents; CDC2 Protein Kinase; CDC28 Protein Kinase, S cerevisiae; Cell Survival; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Kinetin; Purines; Roscovitine; Structure-Activity Relationship; Tumor Cells, Cultured

2002
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
Synthesis and biological evaluation of a selective N- and p/q-type calcium channel agonist.
    ACS medicinal chemistry letters, 2012, Dec-13, Volume: 3, Issue:12

    Topics:

2012
Proteomics approach in classifying the biochemical basis of the anticancer activity of the new olomoucine-derived synthetic cyclin-dependent kinase inhibitor, bohemine.
    Electrophoresis, 2000, Volume: 21, Issue:17

    Topics: Antineoplastic Agents; Cyclin-Dependent Kinases; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Humans; Kinetin; Neoplasm Proteins; Proteome; Purines; Tumor Cells, Cultured

2000
Synthetic inhibitors of CDKs induce different responses in androgen sensitive and androgen insensitive prostatic cancer cell lines.
    Molecular pathology : MP, 2002, Volume: 55, Issue:4

    Topics: Cell Division; Cyclin-Dependent Kinases; Enzyme Inhibitors; Humans; Kinetin; Male; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Purines; Receptors, Androgen; Tumor Cells, Cultured

2002
Comparison of the TUNEL, lamin B and annexin V methods for the detection of apoptosis by flow cytometry.
    Acta histochemica, 2002, Volume: 104, Issue:4

    Topics: Annexin A5; Apoptosis; Dactinomycin; DNA Fragmentation; Enzyme Inhibitors; Etoposide; Flow Cytometry; Fluorescent Antibody Technique, Indirect; HL-60 Cells; Humans; In Situ Nick-End Labeling; Kinetin; Lamin Type B; Purines; Sensitivity and Specificity

2002
Mixed ligand complexes of platinum(II) and palladium(II) with cytokinin-derived compounds Bohemine and Olomoucine: X-ray structure of [Pt(BohH+-N7)Cl(3)].9/5H2O [Boh=6-(benzylamino)-2-[(3-(hydroxypropyl)-amino]-9-isopropylpurine, Bohemine].
    Journal of inorganic biochemistry, 2003, Apr-01, Volume: 94, Issue:4

    Topics: Antineoplastic Agents; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Kinetin; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Organometallic Compounds; Organoplatinum Compounds; Palladium; Platinum; Purines; Structure-Activity Relationship; Tumor Cells, Cultured

2003
In vitro and in vivo pharmacokinetic-pharmacodynamic relationships for the trisubstituted aminopurine cyclin-dependent kinase inhibitors olomoucine, bohemine and CYC202.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Jul-01, Volume: 11, Issue:13

    Topics: Animals; Area Under Curve; Blotting, Western; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinases; Enzyme Inhibitors; Female; HCT116 Cells; Humans; Inhibitory Concentration 50; Kinetin; Maximum Tolerated Dose; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Phosphorylation; Purines; Recombinant Proteins; Retinoblastoma Protein; Roscovitine; Time Factors; Tissue Distribution; Xenograft Model Antitumor Assays

2005
Zinc(II) complexes with potent cyclin-dependent kinase inhibitors derived from 6-benzylaminopurine: synthesis, characterization, X-ray structures and biological activity.
    Journal of inorganic biochemistry, 2006, Volume: 100, Issue:2

    Topics: Antineoplastic Agents; Benzyl Compounds; Cell Line, Tumor; Chlorides; Crystallography, X-Ray; Cyclin-Dependent Kinases; Differential Thermal Analysis; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Kinetin; Ligands; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Organometallic Compounds; Purines; Spectrophotometry, Infrared; Zinc Compounds

2006
Cellular phototoxicity evoked through the inhibition of human ABC transporter ABCG2 by cyclin-dependent kinase inhibitors in vitro.
    Pharmaceutical research, 2009, Volume: 26, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Cell Membrane; Cell Survival; Chlorophyll; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Hematoporphyrins; Humans; Kinetin; Models, Molecular; Molecular Conformation; Molecular Structure; Neoplasm Proteins; Photosensitizing Agents; Protein Kinase Inhibitors; Purines; Quantitative Structure-Activity Relationship; Quinazolines; Roscovitine; Spodoptera; Transfection

2009
The radiosensitising effect of olomoucine derived synthetic cyclin-dependent kinase inhibitors.
    Neoplasma, 2010, Volume: 57, Issue:2

    Topics: Adenocarcinoma; Apoptosis; Blotting, Western; Cell Cycle; Cyclin-Dependent Kinases; Flow Cytometry; Humans; Kinetin; Lung Neoplasms; Protein Kinase Inhibitors; Purines; Radiation-Sensitizing Agents; Roscovitine; Tumor Cells, Cultured; X-Rays

2010
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