Compounds > bn 52063
Page last updated: 2024-09-03

bn 52063 and indomethacin

bn 52063 has been researched along with indomethacin in 3 studies

Compound Research Comparison

Studies
(bn 52063)		Trials
(bn 52063)		Recent Studies (post-2010)
(bn 52063)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
288029,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomybn 52063 (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Braquet, P; Carré, C; Lavaud, P; Mencia-Huerta, JM; Rodrigue, F; Touvay, C1
Aursudkij, B; Barnes, PJ; Chung, KF; Evans, TW; Rogers, DF1
Barnes, PJ; Chung, KF; Evans, TW; Rogers, DF1

Other Studies

3 other study(ies) available for bn 52063 and indomethacin

ArticleYear
Pharmacologic modulation of picryl chloride-induced contact dermatitis in the mouse.
    The Journal of investigative dermatology, 1991, Volume: 97, Issue:1

    Topics: Animals; Betamethasone; Dermatitis, Contact; Dose-Response Relationship, Drug; Indomethacin; Lactones; Male; Methysergide; Mice; Mice, Inbred BALB C; Picryl Chloride; Plant Extracts; Platelet Activating Factor

1991
Inflammatory mediators involved in antigen-induced airway microvascular leakage in guinea pigs.
    The American review of respiratory disease, 1988, Volume: 138, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antigens; Bronchi; Capillary Permeability; Chlorpheniramine; Chromones; Cimetidine; Guinea Pigs; Immunization; Indomethacin; Inflammation; Lactones; Larynx; Male; Nasal Mucosa; Nedocromil; Ovalbumin; Plant Extracts; Pyrazoles; Quinolones; Respiratory System; Trachea; Urinary Bladder

1988
Effect of platelet-activating factor on airway vascular permeability: possible mechanisms.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 63, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Biomechanical Phenomena; Capillary Permeability; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Lactones; Male; Plant Extracts; Platelet Activating Factor; Platelet Count; Pyrazoles; Respiratory System; Time Factors

1987