bn 50739 has been researched along with bepafant in 5 studies
| Studies (bn 50739) | Trials (bn 50739) | Recent Studies (post-2010) (bn 50739) | Studies (bepafant) | Trials (bepafant) | Recent Studies (post-2010) (bepafant) |
|---|---|---|---|---|---|
| 57 | 0 | 1 | 174 | 0 | 5 |
| Protein | Taxonomy | bn 50739 (IC50) | bepafant (IC50) |
|---|---|---|---|
| Platelet-activating factor receptor | Cavia porcellus (domestic guinea pig) | 0.073 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ono, S; Voelkel, NF; Westcott, JY | 1 |
| Häyry, P; Mennander, A; Paavonen, T; Räisänen, A; Ustinov, J | 1 |
| Flickinger, BD; Mustafa, SB; Olson, MS | 1 |
| Howard, KM; Olson, MS | 1 |
| Abdel-Al, M; Ditmyer, M; Howard, KM; Patel, N | 1 |
5 other study(ies) available for bn 50739 and bepafant
| Article | Year |
|---|---|
PAF antagonists inhibit pulmonary vascular remodeling induced by hypobaric hypoxia in rats.
Topics: Animals; Azepines; Endothelins; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Pulmonary Circulation; Rats; Triazoles; Vasoconstriction | 1992 |
Effect of platelet-activating factor (PAF) receptor blockers on smooth muscle cell replication in vitro and allograft arteriosclerosis in vivo.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Autoradiography; Azepines; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Fibroblasts; Male; Muscle, Smooth, Vascular; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Inbred WF; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Transplantation, Homologous; Triazoles | 1993 |
Suppression of lipopolysaccharide-induced nitric oxide synthase expression by platelet-activating factor receptor antagonists in the rat liver and cultured rat Kupffer cells.
Topics: Alanine Transaminase; Animals; Azepines; Cell Nucleus; Cells, Cultured; Cytoplasm; DNA-Binding Proteins; Endotoxemia; Gene Expression Regulation, Enzymologic; I-kappa B Proteins; Kupffer Cells; Lipopolysaccharides; Liver; Male; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic; Triazoles | 1999 |
The expression and localization of plasma platelet-activating factor acetylhydrolase in endotoxemic rats.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Azepines; DNA, Complementary; Endotoxemia; Endotoxins; Kupffer Cells; Leukocytes; Lipopolysaccharides; Liver; Macrophages, Peritoneal; Male; Phospholipases A; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Chloride; Tissue Distribution; Triazoles; Up-Regulation | 2000 |
Lipopolysaccharide and platelet-activating factor stimulate expression of platelet-activating factor acetylhydrolase via distinct signaling pathways.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Azepines; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Imidazoles; Lipopolysaccharides; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, G-Protein-Coupled; RNA, Messenger; Triazoles | 2011 |