Compounds > bmy 7378

bmy 7378 and wb 4101

bmy 7378 has been researched along with wb 4101 in 52 studies

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's22 (42.31)18.2507
2000's25 (48.08)29.6817
2010's5 (9.62)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ballard, S; Blagg, J; Fox, D; Kenny, B1
Angeli, P; Brasili, L; Franchini, S; Leonardi, A; Manicardi, M; Marucci, G; Poggesi, E; Sorbi, C1
Moser, PC1
Costain, WJ; Desautels, M; Mainra, R; Sulakhe, PV1
Aceves, J; Arias-Montaño, JA; Nuñez, A1
Osnes, JB; Sandnes, D; Skomedal, T; Viko, H1
Han, C; Zhang, Y; Zhu, W1
Han, C; Xu, K; Zhang, Y1
Macmillan, JB; McGrath, JC; Smith, KM1
Hussain, MB; Marshall, I2
Drezner, MK; Friedman, PA; Gesek, FA; Liu, F; Nesbitt, T1
Endoh, M; Yang, HT1
Hasegawa, Y; Ono, H; Wada, T1
Kadavil, EA; Oriowo, MA; Yousif, M1
Han, C; Lu, Z; Wei, H; Xu, K; Zhang, Y1
Brown, RD; Daniel, EE; Kwan, CY; Low, AM; Lu-Chao, H; Wang, YF1
Foster, HE; Latifpour, J; Nishi, K; Saito, M; Weiss, RM; Yoshida, M1
Du, XJ; Han, C; Yan, M; Zhang, Y1
García-Sáinz, JA; Torres-Padilla, ME1
Hiraoka, Y; Kato, H; Morikawa, K; Muramatsu, I; Nagata, O; Ohmura, T; Oshita, M; Taniguchi, T; Watanabe, Y1
Avellar, MC; Megale, A; Porto, CS; Silva, MA1
Arias-Montaño, JA; Berger, VA; Soria-Jasso, LE; Young, JM1
Sasa, M; Tanimitsu, N; Tsuru, H; Yajin, K1
Daly, CJ; Heeley, RP; MacKenzie, JF; McGrath, JC; Pediani, JD1
Endoh, M; Norota, I; Qiao, X1
Gaivin, RJ; Gonzalez-Cabrera, P; Perez, DM; Ross, SA; Waugh, DJ; Yun, J; Zuscik, MJ1
Hillier, C; Jarajapu, YP; MacDonald, A1
Koike, K; Yamamoto, Y2
Chiba, S; Taguchi, Y; Yang, XP1
Chiba, S; Tsukada, M1
Katus, HA; Kemken, D; Kurz, T; Mier, K; Richardt, G1
Dyer, DC; Ioudina, MV1
Horinouchi, T; Koike, K; Shibano, M; Tanaka, Y; Yamamoto, Y1
Chen, MZ; Han, JL; Han, QD; Lü, ZZ; Mao, JM; Zhang, YY1
Koss, MC; Yu, Y1
Campos, M; Morais, Pde L; Pupo, AS1
Capello, SA; Chou, EC; Levin, RM; Longhurst, PA1
Avellar, MC; Hamamura, M; Mendes, FR; Porto, CS; Queiróz, DB1
Chen, K; Chen, M; Han, C; Lu, Z; Song, Y; Yan, J; Zhang, Y1
Doze, VA; Hillman, KL; Porter, JE1
Clair, DK; García-Cazarín, ML; Piascik, MT; Smith, JL1
Chu, N; Goyal, R; Longo, LD; Mittal, A; Zhang, L1
Bockman, CS; Dang, HK; Gruber, DD; Scofield, MA; Wangemann, P; Witt, KM1
Dementieva, RE; Fashutdinov, LI; Zefirov, TL; Ziyatdinova, NI1
Benyhe, S; Borsodi, A; Bóta, J; Ducza, E; Gáspár, R; Hajagos-Tóth, J; Samavati, R1
Bolognesi, ML; Budriesi, R; Cavalli, A; Chiarini, A; Gotti, R; Leonardi, A; Melchiorre, C; Minarini, A; Poggesi, E; Recanatini, M; Rosini, M; Tumiatti, V1
Carotti, A; Carrieri, A; Gentili, F; Giannella, M; Leonardi, A; Marucci, G; Melchiorre, C; Piergentili, A; Pigini, M; Poggesi, E; Quaglia, W1
Pedretti, A; Testa, B; Villa, L; Vistoli, G1
Amantini, C; Carrieri, A; Del Bello, F; Farande, Y; Giannella, M; Leonardi, A; Lucciarini, R; Piergentili, A; Pigini, M; Poggesi, E; Quaglia, W; Rafaiani, G; Santoni, G1
Amantini, C; Bonifazi, A; Del Bello, F; Farande, Y; Farfariello, V; Giannella, M; Leonardi, A; Menegon, S; Nabissi, M; Piergentili, A; Pigini, M; Poggesi, E; Quaglia, W; Santoni, G1

Reviews

1 review(s) available for bmy 7378 and wb 4101

ArticleYear
Pharmacological options in the treatment of benign prostatic hyperplasia.
    Journal of medicinal chemistry, 1997, Apr-25, Volume: 40, Issue:9

    Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Controlled Clinical Trials as Topic; Endothelins; Enzyme Inhibitors; Humans; Male; Prostate; Prostatic Hyperplasia; Receptors, Adrenergic, alpha; Structure-Activity Relationship

1997

Other Studies

51 other study(ies) available for bmy 7378 and wb 4101

ArticleYear
1,3-dioxolane-based ligands as a novel class of alpha1-adrenoceptor antagonists.
    Journal of medicinal chemistry, 2003, Apr-10, Volume: 46, Issue:8

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-1 Receptor Antagonists; Animals; Aorta, Thoracic; CHO Cells; Cricetinae; Dioxolanes; Humans; In Vitro Techniques; Ligands; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Spleen; Structure-Activity Relationship; Vas Deferens

2003
The effect of putative 5-HT1A receptor antagonists on 8-OH-DPAT-induced hypothermia in rats and mice.
    European journal of pharmacology, 1991, Feb-07, Volume: 193, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Dioxanes; Dose-Response Relationship, Drug; Hypothermia, Induced; Male; Mice; Piperazines; Prazosin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes

1991
Expressed alpha 1-adrenoceptors in adult rat brown adipocytes are primarily of alpha 1A subtype.
    Canadian journal of physiology and pharmacology, 1996, Volume: 74, Issue:3

    Topics: Adipocytes; Adipose Tissue, Brown; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cell Membrane; Dioxanes; Female; Piperazines; Rats; Receptors, Adrenergic, alpha-1

1996
Noradrenaline-induced inositol phosphate formation in rat striatum is mediated by alpha 1A-adrenoceptors.
    Neuropharmacology, 1996, Volume: 35, Issue:11

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Calcium; Calcium Channel Blockers; Clonidine; Dihydropyridines; Dioxanes; In Vitro Techniques; Inositol Phosphates; Male; Neostriatum; Norepinephrine; Piperazines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1

1996
Alpha 1-adrenoceptor subtypes involved in increased 86Rb+ influx rate and inositol 1,4,5-trisphosphate mass in adult rat cardiomyocytes.
    European journal of pharmacology, 1997, Apr-04, Volume: 323, Issue:2-3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cells, Cultured; Clonidine; Dioxanes; Heart Ventricles; Inositol 1,4,5-Trisphosphate; Myocardium; Piperazines; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Rubidium Radioisotopes

1997
Characterization of subtype of alpha1-adrenoceptor mediating vasoconstriction in perfused rat hind limb.
    European journal of pharmacology, 1997, Jun-18, Volume: 329, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cell Line; Clonidine; Cloning, Molecular; Dioxanes; Dose-Response Relationship, Drug; Extremities; Humans; Indoles; Norepinephrine; Perfusion; Piperazines; Rats; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Vasoconstriction

1997
Alterations of cardiac alpha 1-adrenoceptor subtypes in hypothyroid rats.
    Clinical and experimental pharmacology & physiology, 1997, Volume: 24, Issue:7

    Topics: Adrenergic alpha-Antagonists; Animals; Atrial Function; Binding, Competitive; Dihydropyridines; Dioxanes; DNA Primers; Heart Atria; Hypothyroidism; Male; Myocardial Contraction; Norepinephrine; Phenethylamines; Piperazines; Polymerase Chain Reaction; Protein Binding; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; RNA, Messenger; Tetralones; Thiouracil

1997
Investigation of alpha1-adrenoceptor subtypes mediating vasoconstriction in rabbit cutaneous resistance arteries.
    British journal of pharmacology, 1997, Volume: 122, Issue:5

    Topics: Acetonitriles; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Male; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha-1; Skin; Tetrahydronaphthalenes; Vascular Resistance; Vasoconstriction

1997
Characterization of alpha1-adrenoceptor subtypes mediating contractions to phenylephrine in rat thoracic aorta, mesenteric artery and pulmonary artery.
    British journal of pharmacology, 1997, Volume: 122, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Dioxanes; Dioxins; Dose-Response Relationship, Drug; In Vitro Techniques; Indoles; Indoramin; Isometric Contraction; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Oxathiins; Phenylephrine; Piperazines; Prazosin; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Spiro Compounds; Vasoconstrictor Agents

1997
Proximal nephron Na+/H+ exchange is regulated by alpha 1A- and alpha 1B-adrenergic receptor subtypes.
    Molecular pharmacology, 1997, Volume: 52, Issue:6

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cells, Cultured; Dioxanes; DNA, Complementary; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Mice; Nephrons; Oligonucleotides, Antisense; Piperazines; Polymerase Chain Reaction; Rats; Receptors, Adrenergic, alpha-1; RNA; Sodium-Hydrogen Exchangers; Spiperone; Transcription, Genetic

1997
Pharmacological evidence for alpha(1D)-adrenoceptors in the rabbit ventricular myocardium: analysis with BMY 7378.
    British journal of pharmacology, 1997, Volume: 122, Issue:8

    Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Calcium Channel Blockers; Dihydropyridines; Dioxanes; Dose-Response Relationship, Drug; Heart; Heart Ventricles; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha-1

1997
Characterization of alpha1-adrenoceptor subtypes in facilitation of rat spinal motoneuron activity.
    European journal of pharmacology, 1997, Dec-04, Volume: 340, Issue:1

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Bridged-Ring Compounds; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Epinephrine; Male; Methoxamine; Motor Neurons; Norepinephrine; Oxazines; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Spinal Cord

1997
Heterogeneity of alpha 1-adrenoceptor subtypes mediating noradrenaline-induced contractions of the rat superior mesenteric artery.
    Pharmacology, 1998, Volume: 56, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dioxanes; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Mesenteric Artery, Superior; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Spiperone; Vasoconstriction; Vasoconstrictor Agents

1998
Alteration of alpha1-adrenoceptor subtypes in aortas of 12-month-old spontaneously hypertensive rats.
    European journal of pharmacology, 1998, Feb-26, Volume: 344, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; Dioxanes; Hypertension; Indoles; Male; Muscle Contraction; Norepinephrine; Piperazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Ribonucleases

1998
Pharmacological and immunocytochemical characterization of subtypes of alpha-1 adrenoceptors in dog aorta.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:2

    Topics: Animals; Aorta; Clonidine; Dioxanes; Dogs; Dose-Response Relationship, Drug; Immunohistochemistry; Indoles; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Spiro Compounds

1998
Characterization, localization and distribution of alpha1 adrenoceptor subtype in male rabbit urethra.
    The Journal of urology, 1998, Volume: 160, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Autoradiography; Dioxanes; Immunohistochemistry; Male; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha-1; Spiperone; Urethra

1998
Functional assessment of alpha 1-adrenoceptor subtypes in porcine coronary artery.
    Clinical and experimental pharmacology & physiology, 1998, Volume: 25, Issue:9

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Coronary Vessels; Dioxanes; Humans; In Vitro Techniques; Kinetics; Male; Norepinephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Swine; Vasoconstriction

1998
Modulation of basal intracellular calcium by inverse agonists and phorbol myristate acetate in rat-1 fibroblasts stably expressing alpha1d-adrenoceptors.
    FEBS letters, 1999, Jan-29, Volume: 443, Issue:3

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cell Line; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Endothelin-1; Fibroblasts; Norepinephrine; Phentolamine; Piperazines; Protein Kinase C; Rats; Receptors, Adrenergic, alpha-1; Staurosporine; Tetradecanoylphorbol Acetate; Transfection

1999
Binding and functional characterization of alpha1-adrenoceptor subtypes in the rat prostate.
    European journal of pharmacology, 1999, Jan-29, Volume: 366, Issue:1

    Topics: Acetonitriles; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Dioxanes; Dose-Response Relationship, Drug; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Norepinephrine; Oxymetazoline; Piperazines; Prazosin; Prostate; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Tritium

1999
Expression and pharmacological characterization of alpha1-adrenoceptors in rat seminal vesicle.
    European journal of pharmacology, 1999, Sep-24, Volume: 381, Issue:2-3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Clonidine; Dioxanes; Epinephrine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenoxybenzamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seminal Vesicles

1999
Characterisation of alpha1B-adrenoceptors linked to inositol phosphate formation and calcium mobilisation in human astrocytoma U373 MG cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:5

    Topics: Adrenergic alpha-Antagonists; Astrocytoma; Calcium; Cell Membrane; Clonidine; Dihydropyridines; Dioxanes; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Thymidine; Tumor Cells, Cultured

1999
alpha(1)-adrenoceptor subtypes and effect of alpha(1A)-adrenoceptor agonist NS-49 on guinea pig nasal mucosa vasculature.
    European journal of pharmacology, 2000, Jan-03, Volume: 387, Issue:1

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anilides; Animals; Blood Vessels; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Male; Nasal Mucosa; Norepinephrine; Oxymetazoline; Piperazines; Prazosin; Spiperone; Vasoconstriction; Yohimbine

2000
Alpha(1)-adrenoceptor subtypes mediating contractions of the rat mesenteric artery.
    European journal of pharmacology, 2000, Apr-21, Volume: 395, Issue:1

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; In Vitro Techniques; Indoles; Indoramin; Male; Mesenteric Arteries; Methoxamine; Oxathiins; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Vasoconstriction; Vasoconstrictor Agents

2000
Single-cell recombinant pharmacology: bovine alpha(1a)-adrenoceptors in rat-1 fibroblasts release intracellular ca(2+), display subtype-characteristic agonism and antagonism, and exhibit an antagonist-reversible inverse concentration-response phase.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:3

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Calcium Signaling; Cattle; Dioxanes; Dose-Response Relationship, Drug; Imidazoles; Phenylalanine; Piperazines; Prazosin; Rats; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tetrahydronaphthalenes

2000
Pharmacological characteristics of inhibitory action of the selective alpha1-antagonist JTH-601 on the positive inotropic effect mediated by alpha1-adrenoceptors in isolated rabbit papillary muscle.
    Japanese journal of pharmacology, 2000, Volume: 84, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Cresols; Depression, Chemical; Dihydropyridines; Dioxanes; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Piperazines; Rabbits; Receptors, Adrenergic, alpha-1

2000
Phe-308 and Phe-312 in transmembrane domain 7 are major sites of alpha 1-adrenergic receptor antagonist binding. Imidazoline agonists bind like antagonists.
    The Journal of biological chemistry, 2001, Jul-06, Volume: 276, Issue:27

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Amino Acid Sequence; Animals; Cell Membrane; Clonidine; Conserved Sequence; Cricetinae; Dihydropyridines; Dioxanes; Humans; Imidazoles; Models, Molecular; Molecular Sequence Data; Oxymetazoline; Phenylalanine; Piperazines; Prazosin; Protein Structure, Secondary; Rats; Receptors, Adrenergic, alpha-1; Structure-Activity Relationship

2001
The alpha(1A)-adrenoceptor subtype mediates contraction in rat femoral resistance arteries.
    European journal of pharmacology, 2001, Jun-22, Volume: 422, Issue:1-3

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Femoral Artery; Imidazoles; In Vitro Techniques; Isoquinolines; Male; Naphthyridines; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tetrahydronaphthalenes; Vascular Resistance; Vasoconstriction

2001
Characterization of alpha1-adrenoceptor-mediated contraction in the mouse thoracic aorta.
    European journal of pharmacology, 2001, Jul-20, Volume: 424, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Buspirone; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Epinephrine; In Vitro Techniques; Male; Methoxamine; Mice; Models, Biological; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Serotonin Receptor Agonists; Statistics as Topic; Vasoconstriction

2001
Existence of alpha(1A)- and alpha(1B)-adrenoceptor subtypes in canine mandibular alveolar arteries.
    Clinical and experimental pharmacology & physiology, 2001, Volume: 28, Issue:9

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alveolar Process; Animals; Arteries; Clonidine; Dioxanes; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Mandible; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Vasoconstriction; Xylazine; Yohimbine

2001
alpha(1)-Adrenoceptor subtypes in the mouse mesenteric artery and abdominal aorta.
    British journal of pharmacology, 2001, Volume: 134, Issue:5

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Abdominal; Dioxanes; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mesenteric Arteries; Mice; Norepinephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Vasoconstriction

2001
Existence of functional alpha1A- and alpha1D- but no alpha1B-adrenoceptor subtypes in rat common carotid arteries.
    Japanese journal of pharmacology, 2002, Volume: 88, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carotid Arteries; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Male; Methoxamine; Norepinephrine; Phenylephrine; Piperazines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vasoconstriction

2002
Adrenergic activation of cardiac phospholipase D: role of alpha(1)-adrenoceptor subtypes.
    Cardiovascular research, 2002, Volume: 54, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cardiomegaly; Clonidine; Dioxanes; Male; Myocardium; Norepinephrine; Perfusion; Phospholipase D; Piperazines; Prazosin; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Signal Transduction; Stimulation, Chemical

2002
Pharmacological characterization of alpha1-adrenoceptor subtypes in the bovine tail artery.
    Journal of veterinary pharmacology and therapeutics, 2002, Volume: 25, Issue:5

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Cattle; Dioxanes; Dose-Response Relationship, Drug; Imidazoles; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Tail; Tetrahydronaphthalenes; Vasoconstriction

2002
Pharmacological characterization of alpha1-adrenoceptor in mouse iliac artery.
    European journal of pharmacology, 2002, Dec-05, Volume: 456, Issue:1-3

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; Iliac Artery; In Vitro Techniques; Male; Mice; Norepinephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Vasoconstriction

2002
Functional alpha1-adrenergic receptor subtypes in human right gastroepiploic artery.
    Acta pharmacologica Sinica, 2003, Volume: 24, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Aged; Dioxanes; Female; Gastroepiploic Artery; Humans; Indoles; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Piperazines; Receptors, Adrenergic, alpha-1

2003
Functional characterization of alpha-adrenoceptors mediating pupillary dilation in rats.
    European journal of pharmacology, 2003, Jun-20, Volume: 471, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic Fibers; Animals; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Injections, Intravenous; Male; Mydriasis; Norepinephrine; Phenoxybenzamine; Phentolamine; Piperazines; Prazosin; Pupil; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Yohimbine

2003
Effects of castration and of testosterone replacement on alpha(1)-adrenoceptor subtypes in the rat vas deferens.
    European journal of pharmacology, 2003, Jun-20, Volume: 471, Issue:2

    Topics: Animals; Castration; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Male; Muscle Contraction; Neuronal Plasticity; Norepinephrine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Testosterone; Time Factors; Vas Deferens; Yohimbine

2003
Excitatory alpha1-adrenergic receptors predominate over inhibitory beta-receptors in rabbit dorsal detrusor.
    The Journal of urology, 2003, Volume: 170, Issue:6 Pt 1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Urinary Bladder

2003
Effects of androgen manipulation on alpha1-adrenoceptor subtypes in the rat seminal vesicle.
    Life sciences, 2004, Aug-06, Volume: 75, Issue:12

    Topics: Adrenergic alpha-1 Receptor Antagonists; Analysis of Variance; Androgens; Animals; Autoradiography; Barium Compounds; Chlorides; Clonidine; Cyproterone Acetate; Dioxanes; Gene Expression Regulation; Male; Orchiectomy; Organ Size; Phenylephrine; Piperazines; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; RNA, Messenger; Seminal Vesicles; Testosterone

2004
Different roles of alpha1-adrenoceptor subtypes in mediating cardiomyocyte protein synthesis in neonatal rats.
    Clinical and experimental pharmacology & physiology, 2004, Volume: 31, Issue:9

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Cell Enlargement; Cells, Cultured; Dioxanes; Indoles; Leucine; Muscle Proteins; Myocytes, Cardiac; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1

2004
Alpha1A-adrenergic receptors are functionally expressed by a subpopulation of cornu ammonis 1 interneurons in rat hippocampus.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3

    Topics: Action Potentials; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electrophysiology; Hippocampus; In Vitro Techniques; Interneurons; Isoproterenol; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1

2007
The alpha1D-adrenergic receptor induces vascular smooth muscle apoptosis via a p53-dependent mechanism.
    Molecular pharmacology, 2008, Volume: 74, Issue:4

    Topics: Acetophenones; Adrenergic alpha-1 Receptor Antagonists; Anthracenes; Aorta; Apoptosis; Benzothiazoles; Cells, Cultured; Culture Media, Serum-Free; Dioxanes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Mitochondria; Muscle, Smooth, Vascular; Phenylephrine; Piperazines; Prazosin; Pyridines; Reactive Oxygen Species; Receptors, Adrenergic, alpha-1; Time Factors; Toluene; Tumor Suppressor Protein p53

2008
alpha(1)-Adrenergic receptor subtype function in fetal and adult cerebral arteries.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 298, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Cell Communication; Cerebral Arteries; Dioxanes; Extracellular Signal-Regulated MAP Kinases; Fetus; Inositol 1,4,5-Trisphosphate; Models, Animal; Norepinephrine; Piperazines; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Sheep; Vasoconstriction; Vasoconstrictor Agents

2010
Molecular and pharmacological characteristics of the gerbil α(1a)-adrenergic receptor.
    Hearing research, 2012, Volume: 283, Issue:1-2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Amino Acid Sequence; Animals; Arteries; Chlorocebus aethiops; Clonidine; Cloning, Molecular; Cochlea; Conserved Sequence; COS Cells; Dioxanes; Dose-Response Relationship, Drug; Gerbillinae; Humans; Mice; Molecular Sequence Data; Piperazines; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Sequence Analysis, Protein; Transfection; Vasoconstriction

2012
Blockade of different subtypes of α(1)-adrenoceptors produces opposite effect on heart chronotropy in newborn rats.
    Bulletin of experimental biology and medicine, 2012, Volume: 154, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Animals, Newborn; Clonidine; Dioxanes; Heart Rate; Piperazines; Rats; Receptors, Adrenergic, alpha-1

2012
The effects of female sexual hormones on the expression and function of α1A- and α1D-adrenoceptor subtypes in the late-pregnant rat myometrium.
    European journal of pharmacology, 2015, Dec-15, Volume: 769

    Topics: Animals; Dioxanes; Estradiol; Female; Gene Expression Regulation; Myometrium; Piperazines; Pregnancy; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; RNA, Messenger

2015
WB 4101-related compounds. 2. Role of the ethylene chain separating amine and phenoxy units on the affinity for alpha(1)-adrenoreceptor subtypes and 5-HT(1A) receptors.
    Journal of medicinal chemistry, 1999, Oct-07, Volume: 42, Issue:20

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; CHO Cells; Cloning, Molecular; Cricetinae; Dioxanes; HeLa Cells; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Spleen; Stereoisomerism; Structure-Activity Relationship; Vas Deferens

1999
Structure-activity relationships in 1,4-benzodioxan-related compounds. 7. Selectivity of 4-phenylchroman analogues for alpha(1)-adrenoreceptor subtypes.
    Journal of medicinal chemistry, 2002, Apr-11, Volume: 45, Issue:8

    Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; CHO Cells; Chromans; Cricetinae; Dioxanes; HeLa Cells; Humans; In Vitro Techniques; Male; Models, Molecular; Muscle Contraction; Muscle, Smooth; Prostate; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Spleen; Structure-Activity Relationship; Vas Deferens

2002
Range and sensitivity as descriptors of molecular property spaces in dynamic QSAR analyses.
    Journal of medicinal chemistry, 2005, Jul-28, Volume: 48, Issue:15

    Topics: Chemical Phenomena; Chemistry, Physical; Ligands; Models, Molecular; Molecular Conformation; Monte Carlo Method; Quantitative Structure-Activity Relationship; Receptors, Adrenergic, alpha-1; Solvents

2005
Structure-activity relationships in 1,4-benzodioxan-related compounds. 9. From 1,4-benzodioxane to 1,4-dioxane ring as a promising template of novel alpha1D-adrenoreceptor antagonists, 5-HT1A full agonists, and cytotoxic agents.
    Journal of medicinal chemistry, 2008, Oct-23, Volume: 51, Issue:20

    Topics: Adrenergic alpha-1 Receptor Antagonists; Benzene; Cell Line, Tumor; Cell Survival; Dioxanes; Ethylamines; Humans; Models, Molecular; Molecular Structure; Receptor, Serotonin, 5-HT1A; Receptors, Adrenergic, alpha-1; Serotonin Receptor Agonists; Structure-Activity Relationship

2008
Structure-activity relationships in 1,4-benzodioxan-related compounds. 11. (1) reversed enantioselectivity of 1,4-dioxane derivatives in α1-adrenergic and 5-HT1A receptor binding sites recognition.
    Journal of medicinal chemistry, 2013, Jan-24, Volume: 56, Issue:2

    Topics: Binding Sites; Cell Line; Dioxanes; Humans; Magnetic Resonance Spectroscopy; Receptor, Serotonin, 5-HT1A; Receptors, Adrenergic, alpha-1; Receptors, Serotonin, 5-HT1; Stereoisomerism; Structure-Activity Relationship

2013