bmy 42393 has been researched along with iloprost in 14 studies
| Studies (bmy 42393) | Trials (bmy 42393) | Recent Studies (post-2010) (bmy 42393) | Studies (iloprost) | Trials (iloprost) | Recent Studies (post-2010) (iloprost) |
|---|---|---|---|---|---|
| 21 | 0 | 1 | 2,150 | 271 | 462 |
| Protein | Taxonomy | bmy 42393 (IC50) | iloprost (IC50) |
|---|---|---|---|
| Prostacyclin receptor | Homo sapiens (human) | 0.0112 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (64.29) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brassard, CL; Buchanan, JO; Federici, ME; Fleming, JS; Gamberdella, M; Meanwell, NA; Rosenfeld, MJ; Trehan, AK; Wright, JJ; Zavoico, GB | 1 |
| Brassard, CL; Buchanan, JO; Gougoutas, JZ; Malley, MF; Martin, SW; Meanwell, NA; Romine, JL; Rosenfeld, MJ; Trehan, AK; Wright, JJ | 1 |
| Brassard, CL; Buchanan, JO; Federici, ME; Fleming, JS; Gamberdella, M; Hartl, KS; Meanwell, NA; Rosenfeld, MJ; Wright, JJ; Zavoico, GB | 1 |
| Hattori, K; Okitsu, O; Tabuchi, S; Taniguchi, K | 1 |
| Asaki, T; Hamamoto, T; Kuwabara, K; Kuwano, K; Sugiyama, Y | 1 |
| Asaki, T; Hamamoto, T; Kuwabara, K; Kuwano, K; Niwa, T; Sugiyama, Y | 1 |
| Meanwell, NA | 1 |
| Brassard, CL; Buchanan, JO; Federici, ME; Fleming, JS; Gamberdella, M; Hartl, KS; Meanwell, NA; Rosenfeld, MJ; Trehan, AK; Wright, JJ | 1 |
| Wise, H | 2 |
| Brassard, CL; Federici, ME; Meanwell, NA; Romine, J; Seiler, SM | 1 |
| Chan, HW; Ho, JK; Jones, RL; Lam, WL; Qian, YM; Wise, H; Wong, HN; Yim, AP | 1 |
| Chow, KB; Wise, H | 1 |
| Chow, KB; Wise, H; Wong, YH | 1 |
14 other study(ies) available for bmy 42393 and iloprost
| Article | Year |
|---|---|
Nonprostanoid prostacyclin mimetics. 2. 4,5-Diphenyloxazole derivatives.
Topics: Adenosine Diphosphate; Cell Membrane; Humans; Oxazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Structure-Activity Relationship | 1992 |
Nonprostanoid prostacyclin mimetics. 5. Structure-activity relationships associated with [3-[4-(4,5-diphenyl-2-oxazolyl)-5- oxazolyl]phenoxy]acetic acid.
Topics: Acetates; Adenosine Diphosphate; Binding, Competitive; Crystallization; Epoprostenol; Humans; Hydrogen Bonding; Iloprost; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Oxazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Epoprostenol; Receptors, Prostaglandin; Structure-Activity Relationship | 1993 |
Nonprostanoid prostacyclin mimetics. 4. Derivatives of 2-[3-[2-(4,5-diphenyl-2-oxazolyl)ethyl]phenoxy]acetic acid substituted alpha to the oxazole ring.
Topics: Adenosine Diphosphate; Epoprostenol; Humans; Hydrogen Bonding; Molecular Structure; Oxazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Epoprostenol; Receptors, Prostaglandin; Structure-Activity Relationship | 1993 |
A simple stereoselective synthesis and biological evaluation of FR181157: orally active prostacyclin mimetic.
Topics: Administration, Oral; Animals; Area Under Curve; Epoprostenol; Fasting; Models, Molecular; Molecular Conformation; Oxazoles; Stereoisomerism; Structure-Activity Relationship | 2003 |
Structure-activity studies on diphenylpyrazine derivatives: a novel class of prostacyclin receptor agonists.
Topics: Humans; Pyrazines; Receptors, Epoprostenol; Structure-Activity Relationship | 2007 |
Structure-activity relationship study on the 6-membered heteroaromatic ring system of diphenylpyrazine-type prostacyclin receptor agonists.
Topics: Heterocyclic Compounds; Humans; Molecular Structure; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazines; Receptors, Epoprostenol; Structure-Activity Relationship | 2007 |
Synopsis of some recent tactical application of bioisosteres in drug design.
Topics: Cytochrome P-450 Enzyme System; Drug Design | 2011 |
Non-prostanoid prostacyclin mimetics. 6. Derivatives of 2-[3-[2-(4,5-Diphenyl-2-oxazolyl)ethyl]phenoxy]acetic acid modified beta-to the oxazole ring.
Topics: Cell Membrane; Humans; Iloprost; Oxazoles; Phenoxyacetates; Platelet Aggregation Inhibitors; Structure-Activity Relationship | 1994 |
The inhibitory effects of non-prostanoid prostacyclin mimetics on rat neutrophil function.
Topics: Acetates; Animals; Calcium; Cell Aggregation; Cyclic AMP; Drug Design; Epoprostenol; Glyburide; Iloprost; Imidazoles; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxazoles; Phenoxyacetates; Phosphodiesterase Inhibitors; Prostaglandins, Synthetic; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin | 1996 |
[3-[4-(4,5-Diphenyl-2-oxazolyl)-5-oxazolyl]phenoxy]acetic acid (BMY 45778) is a potent non-prostanoid prostacyclin partial agonist: effects on platelet aggregation, adenylyl cyclase, cAMP levels, protein kinase, and iloprost binding.
Topics: Acetates; Adenylyl Cyclases; Animals; Binding, Competitive; Cell Membrane; Cyclic AMP; Epoprostenol; GTP Phosphohydrolases; Humans; Iloprost; Imidazoles; Oxazoles; Phenoxyacetates; Platelet Aggregation Inhibitors; Protein Kinases; Rabbits; Rats | 1997 |
Relaxant actions of nonprostanoid prostacyclin mimetics on human pulmonary artery.
Topics: Acetates; Aged; Cardiovascular Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epoprostenol; Fatty Acids; Humans; Iloprost; Imidazoles; Indoles; Middle Aged; Muscle, Smooth, Vascular; Oxazoles; Phenoxyacetates; Platelet Aggregation Inhibitors; Prostaglandins, Synthetic; Pulmonary Artery; Receptors, Epoprostenol; Receptors, Prostaglandin; Structure-Activity Relationship; Vasoconstrictor Agents; Vasodilator Agents | 1997 |
The effect of prostacyclin mimetics on neutrophil function.
Topics: Acetates; Animals; Cell Aggregation; Cyclic AMP; Epoprostenol; Iloprost; Imidazoles; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxazoles; Peritoneal Cavity; Phenoxyacetates; Pyrrolidinones; Rats; Rolipram; Second Messenger Systems; Sulfonamides | 1997 |
The effect of non-prostanoid prostacyclin mimetics on cyclic AMP production by neuronal SK-N-SH cells.
Topics: Acetates; Cell Line; Cyclic AMP; Epoprostenol; Humans; Iloprost; Imidazoles; Kinetics; Neuroblastoma; Neurons; Oxazoles; Phenoxyacetates | 1997 |
Prostacyclin receptor-independent inhibition of phospholipase C activity by non-prostanoid prostacyclin mimetics.
Topics: Acetates; Adenylyl Cyclases; Alprostadil; Animals; Cell Survival; CHO Cells; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epoprostenol; Iloprost; Imidazoles; Inositol Phosphates; Oxazoles; Phenoxyacetates; Pyridines; Receptors, Epoprostenol; Receptors, Prostaglandin; Transfection; Tritium; Type C Phospholipases | 2001 |