bms-806 has been researched along with fluoromethyl-2-2-difluoro-1-(trifluoromethyl)vinyl-ether* in 1 studies
1 other study(ies) available for bms-806 and fluoromethyl-2-2-difluoro-1-(trifluoromethyl)vinyl-ether
| Article | Year |
|---|---|
Inhibition of human immunodeficiency virus envelope glycoprotein- mediated single cell lysis by low-molecular-weight antagonists of viral entry.
The coexpression of human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins and receptors leads to the lysis of single cells by a process that is dependent upon membrane fusion. This cell lysis was inhibited by low-molecular-weight compounds that interfere with receptor binding or with receptor-induced conformational transitions in the envelope glycoproteins. A peptide, T20, potently inhibited cell-cell fusion but had no effect on single cell lysis mediated by the HIV-1 envelope glycoproteins. Thus, critical events in the lysis of single cells by the HIV-1 envelope glycoproteins occur in intracellular compartments accessible only to small inhibitory compounds. Topics: Animals; Cell Line; Cytopathogenic Effect, Viral; Dogs; Enfuvirtide; Ethers; Gene Products, env; HIV Envelope Protein gp41; HIV-1; Humans; Hydrocarbons, Fluorinated; Membrane Fusion; Molecular Weight; Peptide Fragments; Piperazines | 2007 |