bms-536924 has been researched along with epigallocatechin-gallate* in 1 studies
1 review(s) available for bms-536924 and epigallocatechin-gallate
Article | Year |
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[Progress in the studies on small molecule IGF-1R inhibitors].
The importance of insulin-like growth factor 1 receptor (IGF-1R) signaling in malignant behaviour of tumour cells is well established. Inhibiting the activity of IGF-1R may result in striking apoptosis in malignant cells growing. IGF-1R antibodies which are currently in phase I and II clinical trials and several IGF-IR TKIs have preclinically been characterized. This review describes recent developments of small molecule tyrosine kinase inhibitors. Topics: Animals; Apoptosis; Benzimidazoles; Catechin; Cell Line, Tumor; Humans; Neoplasms; Piperazines; Protein Kinase Inhibitors; Pyridones; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Signal Transduction | 2008 |