bms-536924 and epigallocatechin-gallate

bms-536924 has been researched along with epigallocatechin-gallate* in 1 studies

Reviews

1 review(s) available for bms-536924 and epigallocatechin-gallate

ArticleYear
[Progress in the studies on small molecule IGF-1R inhibitors].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2008, Volume: 43, Issue:10

    The importance of insulin-like growth factor 1 receptor (IGF-1R) signaling in malignant behaviour of tumour cells is well established. Inhibiting the activity of IGF-1R may result in striking apoptosis in malignant cells growing. IGF-1R antibodies which are currently in phase I and II clinical trials and several IGF-IR TKIs have preclinically been characterized. This review describes recent developments of small molecule tyrosine kinase inhibitors.

    Topics: Animals; Apoptosis; Benzimidazoles; Catechin; Cell Line, Tumor; Humans; Neoplasms; Piperazines; Protein Kinase Inhibitors; Pyridones; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Signal Transduction

2008