bms-275183 and taxane

bms-275183 has been researched along with taxane* in 1 studies

Other Studies

1 other study(ies) available for bms-275183 and taxane

Article	Year
The discovery of BMS-275183: an orally efficacious novel taxane. Bioorganic & medicinal chemistry, 2003, Oct-01, Volume: 11, Issue:20 The evolution of 2, a C-4-methylcarbonate analogue of paclitaxel with minimal oral bioavailability and oral efficacy, into its C-3'-t-butyl-3'-N-t-butyloxycarbonyl analogue (15i), a novel taxane with oral efficacy in preclinical models that is comparable to iv administered paclitaxel, is described. Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Bridged-Ring Compounds; Cell Line, Tumor; Cell Survival; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Mice; Rats; Structure-Activity Relationship; Taxoids	2003

Article

Year

The discovery of BMS-275183: an orally efficacious novel taxane.

Bioorganic & medicinal chemistry, 2003, Oct-01, Volume: 11, Issue:20

The evolution of 2, a C-4-methylcarbonate analogue of paclitaxel with minimal oral bioavailability and oral efficacy, into its C-3'-t-butyl-3'-N-t-butyloxycarbonyl analogue (15i), a novel taxane with oral efficacy in preclinical models that is comparable to iv administered paclitaxel, is described.

Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Bridged-Ring Compounds; Cell Line, Tumor; Cell Survival; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Mice; Rats; Structure-Activity Relationship; Taxoids

2003