Page last updated: 2024-09-05

bisdethiobis(methylthio)gliotoxin and gliotoxin

bisdethiobis(methylthio)gliotoxin has been researched along with gliotoxin in 10 studies

Compound Research Comparison

Studies
(bisdethiobis(methylthio)gliotoxin)
Trials
(bisdethiobis(methylthio)gliotoxin)
Recent Studies (post-2010)
(bisdethiobis(methylthio)gliotoxin)
Studies
(gliotoxin)
Trials
(gliotoxin)
Recent Studies (post-2010) (gliotoxin)
13084681169

Protein Interaction Comparison

ProteinTaxonomybisdethiobis(methylthio)gliotoxin (IC50)gliotoxin (IC50)
Histone-lysine N-methyltransferase SUV39H1Homo sapiens (human)0.26
Acetolactate synthase catalytic subunit, mitochondrialSaccharomyces cerevisiae S288C0.2
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaHomo sapiens (human)1.1
Protein farnesyltransferase subunit betaHomo sapiens (human)1.1
E3 ubiquitin-protein ligase RNF31Homo sapiens (human)0.51
Histone-lysine N-methyltransferase EHMT2Homo sapiens (human)3.465
RanBP-type and C3HC4-type zinc finger-containing protein 1Homo sapiens (human)0.51
SharpinHomo sapiens (human)0.51

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's5 (50.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Ang, KH; Compton, JE; Crews, P; McKerrow, J; Ratnam, J; Tenney, K; Watts, KR1
Kim, YJ; Kwon, HC; Lee, KR; Park, HB; Park, JS; Yang, HO1
Matsunaga, S; Nogi, Y; Okada, S; Sun, Y; Takada, K; Takemoto, Y; Yoshida, M1
Aoki, H; Kohsaka, M; Nishikawa, M; Okamoto, M; Uchida, I; Yoshida, K1
Aoki, H; Kohsaka, M; Okamoto, M; Uchida, I; Yoshida, K1
Hemmi, K; Okamoto, M; Shimazaki, N; Yoshida, K1
Arai, H; Bennett, SA; Bonin, F; Franks, DJ; Lallier, J; Migahed, L; Mo, F; Ryan, SD1
Colmenarejo, C; Delgado, P; Domingo, MP; Gálvez, EM; Jarne, C; Martínez-Lostao, L; Meis, JF; Müllbacher, A; Pardo, J; Revillo, MJ; Rezusta, A; Roc, L1
Desmet, K; Lagrou, K; Maertens, J; Mercier, T; Reséndiz Sharpe, A; Waumans, D1
Gomez-Lopez, A; Pando Pozo, R; Rueda, C; Sanchez Gonzalez, LM1

Reviews

1 review(s) available for bisdethiobis(methylthio)gliotoxin and gliotoxin

ArticleYear
PAF inhibitors of microbial origin. Studies on diketopiperazine derivatives.
    Progress in biochemical pharmacology, 1988, Volume: 22

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacteria; Chemical Phenomena; Chemistry; Gliotoxin; Hypersensitivity; In Vitro Techniques; Indoles; Nephrosis; Piperazines; Platelet Activating Factor; Rabbits; Shock, Septic

1988

Other Studies

9 other study(ies) available for bisdethiobis(methylthio)gliotoxin and gliotoxin

ArticleYear
Assessing the trypanocidal potential of natural and semi-synthetic diketopiperazines from two deep water marine-derived fungi.
    Bioorganic & medicinal chemistry, 2010, Apr-01, Volume: 18, Issue:7

    Topics: Acetylation; Animals; Aspergillus fumigatus; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diketopiperazines; Drug Evaluation, Preclinical; Fungi; Geologic Sediments; Humans; Indicators and Reagents; Jurkat Cells; Magnetic Resonance Spectroscopy; Methylation; Piperazines; Spiro Compounds; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

2010
Glionitrin B, a cancer invasion inhibitory diketopiperazine produced by microbial coculture.
    Journal of natural products, 2011, Oct-28, Volume: 74, Issue:10

    Topics: Antineoplastic Agents; Aspergillus fumigatus; Diketopiperazines; Drug Screening Assays, Antitumor; Humans; Male; Molecular Structure; Prostatic Neoplasms; Sphingomonas

2011
Gliotoxin analogues from a marine-derived fungus, Penicillium sp., and their cytotoxic and histone methyltransferase inhibitory activities.
    Journal of natural products, 2012, Jan-27, Volume: 75, Issue:1

    Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Gliotoxin; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Japan; Leukemia P388; Molecular Structure; Penicillium

2012
Studies of platelet activating factor (PAF) antagonists from microbial products. I. Bisdethiobis(methylthio)gliotoxin and its derivatives.
    Chemical & pharmaceutical bulletin, 1986, Volume: 34, Issue:1

    Topics: Animals; Fermentation; Gliotoxin; Male; Mycotoxins; Penicillium; Platelet Activating Factor; Rats; Structure-Activity Relationship

1986
Studies of platelet activating factor (PAF) antagonists from microbial products. II. Pharmacological studies of FR-49175 in animal models.
    Chemical & pharmaceutical bulletin, 1986, Volume: 34, Issue:1

    Topics: Anaphylaxis; Animals; Blood Pressure; Bronchi; Capillary Permeability; Gliotoxin; Guinea Pigs; Male; Mice; Mycotoxins; Penicillium; Platelet Activating Factor; Rats; Rats, Inbred Strains

1986
Anti-apoptotic actions of the platelet-activating factor acetylhydrolase I alpha2 catalytic subunit.
    The Journal of biological chemistry, 2004, Dec-10, Volume: 279, Issue:50

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Apoptosis; Base Sequence; Brain; Catalytic Domain; Diterpenes; Ginkgolides; Gliotoxin; Lactones; Mice; Mice, Inbred C57BL; Molecular Sequence Data; PC12 Cells; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Subunits; Rats; Receptors, G-Protein-Coupled; RNA Interference; RNA, Small Interfering; Signal Transduction

2004
Bis(methyl)gliotoxin proves to be a more stable and reliable marker for invasive aspergillosis than gliotoxin and suitable for use in diagnosis.
    Diagnostic microbiology and infectious disease, 2012, Volume: 73, Issue:1

    Topics: Aspergillosis; Aspergillus fumigatus; Blood Chemical Analysis; Culture Media; Gliotoxin; Humans; Sensitivity and Specificity; Virulence Factors

2012
Gliotoxin and bis(methylthio)gliotoxin are not reliable as biomarkers of invasive aspergillosis.
    Mycoses, 2019, Volume: 62, Issue:10

    Topics: Biomarkers; Bronchoalveolar Lavage Fluid; Diagnostic Tests, Routine; Galactose; Gliotoxin; Humans; Invasive Pulmonary Aspergillosis; Mannans; Prospective Studies; Serum

2019
Dynamics of gliotoxin and bis(methylthio)gliotoxin production during the course of Aspergillus fumigatus infection.
    Medical mycology, 2022, Apr-27, Volume: 60, Issue:4

    Topics: Animals; Aspergillosis; Aspergillus fumigatus; Gliotoxin; Virulence

2022