bisdesmoside and thiazolyl-blue

bisdesmoside has been researched along with thiazolyl-blue* in 1 studies

Other Studies

1 other study(ies) available for bisdesmoside and thiazolyl-blue

Article	Year
A new cyclic bisdesmoside from Actinostemma lobatum Maxim. Die Pharmazie, 2015, Volume: 70, Issue:5 A new cyclic bisdesmoside treterpene saponin, lobatoside N (1), together with four known triterpenoids, was isolated from the herb of Actinostemma lobatum Maxim. Structures were established by means of extensive spectral data analysis. Furthermore, the cytotoxic activities of the identified compounds were evaluated using HCT-116, HT-29, MCF-7 and A549 human cancer cell lines. As a result, compounds 1-5 showed significant cytotoxicities in a dose-dependent manner against the cell lines tested. Especially, compound 5 exhibited stronger activities, with IC50 value of 0.88 μM and 0.98 μM, than that of the positive control drug (Cis-platinum) against HT-29 and A549 cell lines. Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cisplatin; Coloring Agents; Cucurbitaceae; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Saponins; Tetrazolium Salts; Thiazoles; Triterpenes	2015

Article

Year

A new cyclic bisdesmoside from Actinostemma lobatum Maxim.

Die Pharmazie, 2015, Volume: 70, Issue:5

A new cyclic bisdesmoside treterpene saponin, lobatoside N (1), together with four known triterpenoids, was isolated from the herb of Actinostemma lobatum Maxim. Structures were established by means of extensive spectral data analysis. Furthermore, the cytotoxic activities of the identified compounds were evaluated using HCT-116, HT-29, MCF-7 and A549 human cancer cell lines. As a result, compounds 1-5 showed significant cytotoxicities in a dose-dependent manner against the cell lines tested. Especially, compound 5 exhibited stronger activities, with IC50 value of 0.88 μM and 0.98 μM, than that of the positive control drug (Cis-platinum) against HT-29 and A549 cell lines.

Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cisplatin; Coloring Agents; Cucurbitaceae; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Saponins; Tetrazolium Salts; Thiazoles; Triterpenes

2015