bisbenzimidazole and netropsin

bisbenzimidazole has been researched along with netropsin in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199012 (28.57)18.7374
1990's18 (42.86)18.2507
2000's11 (26.19)29.6817
2010's1 (2.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cory, M; Fairley, TA; Tidwell, RR1
Bentley, JA; Cory, M; Donkor, I; Fairley, TA; Lombardy, RJ; Naiman, NA; Ohemeng, KA; Tidwell, RR1
Schneider, HJ1
Adnet, F; Liquier, J; Lown, JW; Rao, KE; Singh, MP; Taillandier, E1
Haaf, T; Hoehn, H; Kausch, K; Köhler, J; Poot, M1
Dervan, PB; Harshman, KD1
Dervan, PB1
Dickerson, RE; Goodsell, D1
Wähnert, U; Zimmer, C1
Dickerson, RE; Grzeskowiak, K; Pjura, PE1
Gago, F; Reynolds, CA; Richards, WG1
Aymami, J; Carrondo, MA; Coll, M; Rich, A; van Boom, JH; van der Marel, GA; Wang, AH1
Dickerson, RE; Goodsell, DS; Kopka, ML; Pjura, PE1
Jorgenson, KF; van de Sande, JH; Varshney, U1
Latt, SA; Sahar, E1
Rønne, M; Thust, R1
Dill, FJ; Jacky, PB1
Akhebat, A; Fritzsche, H; Jovin, TM; Rippe, K; Taillandier, E1
Friedman, RA; Honig, B; Misra, VK; Sharp, KA1
Beerman, TA; Chiang, SY; Rauscher, FJ; Welch, J1
Durand, M; Maurizot, JC; Thuong, NT1
Bär, H; Burckhardt, G; Triebel, H; Walter, A; Zimmer, C1
Heimpel, S; Hiller, KH; Hoehn, H; Poot, M1
Abu-Daya, A; Brown, PM; Fox, KR1
Ginsburg, H; Krugliak, M; Nissani, E; Williamson, DH1
Bailly, C; Colson, P; Hamy, F; Houssier, C1
Brown, PM; Fox, KR1
Brazil-Zison, M; Dickerson, RE; Filipowsky, ME; Kopka, ML; Lown, JW1
Reinert, KE; Steinmetzer, K1
Hamdan, II; Skellern, GG; Waigh, RD2
Gallagher, K; Sharp, K1
Bailly, C; Bajic, M; Boykin, DW; Ding, D; Kumar, A; Wang, L; Wilson, WD1
Lown, JW; Reddy, BS; Sharma, SK1
Denny, WA1
Boger, DL; Brunette, SR; Fink, BE; Hedrick, MP; Tse, WC1
Neidle, S1
Flader, W; Hallbrucker, A; Liedl, KR; Mayer, E; Wellenzohn, B; Winger, RH1
Ayusawa, D; Fujii, M; Michishita, E; Ogino, H; Suzuki, T1
Bielawska, A; Bielawski, K; Midura-Nowaczek, K; Pućkowska, A1
Luque, FJ; Orozco, M; Rueda, M1
Chopra, A; Gupta, SP; Kumar, S; Pandav, K; Pandya, P1

Reviews

6 review(s) available for bisbenzimidazole and netropsin

ArticleYear
Ligand binding to nucleic acids and proteins: Does selectivity increase with strength?
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:11

    Topics: Ligands; Nucleic Acids; Proteins; Receptors, Opioid; Substrate Specificity

2008
Nonintercalating DNA-binding ligands: specificity of the interaction and their use as tools in biophysical, biochemical and biological investigations of the genetic material.
    Progress in biophysics and molecular biology, 1986, Volume: 47, Issue:1

    Topics: Aminoglycosides; Animals; Anthramycin; Antibiotics, Antineoplastic; Base Sequence; Binding Sites; Bisbenzimidazole; Cattle; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry, Physical; Chromosomes; Circular Dichroism; Diminazene; Distamycins; DNA; DNA, Superhelical; Drug Interactions; Duocarmycins; Indoles; Leucomycins; Ligands; Magnetic Resonance Spectroscopy; Mathematics; Models, Molecular; Netropsin; Plicamycin; Protein Conformation; Pyridinium Compounds; RNA; Spectrophotometry, Ultraviolet; Staining and Labeling; Thermodynamics

1986
Energy transfer and binding competition between dyes used to enhance staining differentiation in metaphase chromosomes.
    Chromosoma, 1980, Volume: 79, Issue:1

    Topics: Animals; Base Sequence; Binding, Competitive; Bisbenzimidazole; Cattle; Chromomycin A3; Chromosome Banding; Dactinomycin; DNA; Energy Transfer; Ethidium; Humans; Mathematics; Methyl Green; Microscopy, Fluorescence; Netropsin; Quinacrine; Staining and Labeling

1980
Recent developments in sequence selective minor groove DNA effectors.
    Current medicinal chemistry, 2001, Volume: 8, Issue:5

    Topics: Animals; Anthraquinones; Benzimidazoles; Bisbenzimidazole; Bleomycin; Chemistry, Pharmaceutical; Cross-Linking Reagents; Distamycins; DNA; Drug Design; Duocarmycins; Humans; Indoles; Leucomycins; Ligands; Netropsin; Urea

2001
DNA minor groove alkylating agents.
    Current medicinal chemistry, 2001, Volume: 8, Issue:5

    Topics: Alkylating Agents; Animals; Anthramycin; Antibiotics, Antineoplastic; Benzofurans; Bisbenzimidazole; Chlorambucil; Cyclohexanecarboxylic Acids; Cyclohexenes; Distamycins; DNA; Duocarmycins; Humans; Indoles; Netropsin; Nitrogen Mustard Compounds; Pyrroles; Structure-Activity Relationship

2001
DNA minor-groove recognition by small molecules.
    Natural product reports, 2001, Volume: 18, Issue:3

    Topics: Base Sequence; Benzimidazoles; Bisbenzimidazole; Crystallography, X-Ray; Diminazene; Distamycins; DNA; DNA Probes; DNA-Binding Proteins; Indoles; Ligands; Molecular Conformation; Molecular Structure; Netropsin; Nylons; Oligodeoxyribonucleotides; Sequence Analysis, DNA

2001

Other Studies

36 other study(ies) available for bisbenzimidazole and netropsin

ArticleYear
Structure and DNA binding activity of analogues of 1,5-bis(4-amidinophenoxy)pentane (pentamidine)
    Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3

    Topics: DNA; Models, Molecular; Pentamidine

1992
Structure, DNA minor groove binding, and base pair specificity of alkyl- and aryl-linked bis(amidinobenzimidazoles) and bis(amidinoindoles).
    Journal of medicinal chemistry, 1993, Jun-11, Volume: 36, Issue:12

    Topics: Amidines; Animals; Base Composition; Benzimidazoles; Binding Sites; Cattle; Chemical Phenomena; Chemistry, Physical; DNA; Electrochemistry; Hot Temperature; Hydrogen Bonding; Indoles; Molecular Structure; Poly dA-dT; Polydeoxyribonucleotides; Structure-Activity Relationship; Viscosity

1993
FTIR study of specific binding interactions between DNA minor groove binding ligands and polynucleotides.
    Journal of biomolecular structure & dynamics, 1992, Volume: 10, Issue:3

    Topics: Bisbenzimidazole; DNA; Fourier Analysis; Netropsin; Nucleic Acid Conformation; Polynucleotides; Pyrroles; Spectrophotometry, Infrared; Thiazoles

1992
The minor-groove binding DNA-ligands netropsin, distamycin A and berenil cause polyploidisation via impairment of the G2 phase of the cell cycle.
    Cell structure and function, 1990, Volume: 15, Issue:3

    Topics: Amidines; Bisbenzimidazole; Bromodeoxyuridine; Diminazene; Distamycins; DNA; Fibroblasts; Flow Cytometry; Guanidines; Humans; In Vitro Techniques; Interphase; Netropsin; Polyploidy; Pyrroles

1990
Molecular recognition of B-DNA by Hoechst 33258.
    Nucleic acids research, 1985, Jul-11, Volume: 13, Issue:13

    Topics: Base Sequence; Benzimidazoles; Binding Sites; Bisbenzimidazole; Distamycins; DNA; Netropsin

1985
Design of sequence-specific DNA-binding molecules.
    Science (New York, N.Y.), 1986, Apr-25, Volume: 232, Issue:4749

    Topics: Base Sequence; Bisbenzimidazole; Dactinomycin; Distamycins; DNA; Edetic Acid; Iron; Models, Chemical; Netropsin; Organometallic Compounds; Pyrroles; Structure-Activity Relationship

1986
Isohelical analysis of DNA groove-binding drugs.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:5

    Topics: Bisbenzimidazole; Distamycins; DNA; Mathematics; Models, Molecular; Netropsin; Nucleic Acid Conformation; Substrate Specificity

1986
Binding of Hoechst 33258 to the minor groove of B-DNA.
    Journal of molecular biology, 1987, Sep-20, Volume: 197, Issue:2

    Topics: Base Sequence; Benzimidazoles; Binding Sites; Bisbenzimidazole; Computer Graphics; Crystallography; DNA; Models, Molecular; Netropsin; Nucleic Acid Conformation; Software

1987
The binding of nonintercalative drugs to alternating DNA sequences.
    Molecular pharmacology, 1989, Volume: 35, Issue:2

    Topics: Base Sequence; Bisbenzimidazole; Diminazene; Distamycins; DNA; Netropsin; Nucleic Acid Conformation; Poly dA-dT; Polydeoxyribonucleotides; Thermodynamics

1989
Binding of a Hoechst dye to d(CGCGATATCGCG) and its influence on the conformation of the DNA fragment.
    Biochemistry, 1989, Sep-19, Volume: 28, Issue:19

    Topics: Base Sequence; Benzimidazoles; Bisbenzimidazole; DNA; Netropsin; Nucleic Acid Conformation

1989
The effect of crystal packing on oligonucleotide double helix structure.
    Journal of biomolecular structure & dynamics, 1987, Volume: 5, Issue:3

    Topics: Antineoplastic Agents; Base Sequence; Bisbenzimidazole; Indoles; Isomerism; Models, Molecular; Netropsin; Nucleic Acid Conformation; Oligodeoxyribonucleotides; X-Ray Diffraction

1987
Interaction of Hoechst 33258 with repeating synthetic DNA polymers and natural DNA.
    Journal of biomolecular structure & dynamics, 1988, Volume: 5, Issue:5

    Topics: Base Composition; Benzimidazoles; Binding Sites; Bisbenzimidazole; Dactinomycin; DNA; Methylation; Netropsin; Nucleic Acid Conformation; Nucleotide Mapping; Oligodeoxyribonucleotides

1988
Structural modifications induced in Chinese hamster V79--E chromosomes by prefixation treatment in vitro with the AT-specific agents netropsin, distamycin A, and Hoechst 33258.
    Hereditas, 1981, Volume: 94, Issue:2

    Topics: Animals; Benzimidazoles; Bisbenzimidazole; Chromosomes; Cricetinae; Cricetulus; Distamycins; Guanidines; Netropsin; Pyrroles

1981
Fragile X chromosome and chromosome condensation.
    Annales de genetique, 1983, Volume: 26, Issue:3

    Topics: Aged; Bisbenzimidazole; Chromosome Fragile Sites; Chromosome Fragility; Dactinomycin; Ethidium; Female; Humans; Lymphocytes; Male; Netropsin; Olivomycins; X Chromosome

1983
Structure and drug interactions of parallel-stranded DNA studied by infrared spectroscopy and fluorescence.
    Nucleic acids research, 1993, Nov-11, Volume: 21, Issue:22

    Topics: Base Composition; Base Sequence; Bisbenzimidazole; Distamycins; DNA; Molecular Sequence Data; Netropsin; Nucleic Acid Conformation; Spectrometry, Fluorescence; Spectrophotometry, Infrared

1993
Salt effects on ligand-DNA binding. Minor groove binding antibiotics.
    Journal of molecular biology, 1994, Apr-29, Volume: 238, Issue:2

    Topics: Anti-Bacterial Agents; Base Sequence; Bisbenzimidazole; DNA; Electrochemistry; Indoles; Ligands; Models, Chemical; Molecular Sequence Data; Netropsin; Salts; Thermodynamics

1994
Effects of minor groove binding drugs on the interaction of TATA box binding protein and TFIIA with DNA.
    Biochemistry, 1994, Jun-14, Volume: 33, Issue:23

    Topics: Base Sequence; Bisbenzimidazole; Distamycins; DNA; DNA-Binding Proteins; Duocarmycins; Indoles; Intercalating Agents; Leucomycins; Molecular Sequence Data; Netropsin; Protein Binding; TATA Box; TATA-Box Binding Protein; Transcription Factor TFIIA; Transcription Factors

1994
Interaction of Hoechst 33258 with a DNA triple helix.
    Biochimie, 1994, Volume: 76, Issue:2

    Topics: Bisbenzimidazole; Circular Dichroism; DNA; Hot Temperature; Netropsin; Spectrum Analysis; Structure-Activity Relationship

1994
Modulation of DNA supercoiling by interaction with netropsin and other minor groove binders.
    Journal of biomolecular structure & dynamics, 1994, Volume: 11, Issue:5

    Topics: Base Sequence; Binding Sites; Bisbenzimidazole; DNA, Superhelical; Escherichia coli; Ethidium; Molecular Sequence Data; Netropsin; Nucleic Acid Conformation; Pentamidine; Plasmids; Pyridinium Compounds

1994
Distinct patterns of cell cycle disturbance elicited by compounds interfering with DNA topoisomerase I and II activity.
    Experimental cell research, 1995, Volume: 218, Issue:1

    Topics: Amsacrine; Bisbenzimidazole; Camptothecin; Cell Cycle; Cell Line; Distamycins; DNA; Dose-Response Relationship, Drug; Ethidium; Flow Cytometry; Humans; Intercalating Agents; Kinetics; Lymphocytes; Netropsin; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1995
DNA sequence preferences of several AT-selective minor groove binding ligands.
    Nucleic acids research, 1995, Sep-11, Volume: 23, Issue:17

    Topics: Base Composition; Base Sequence; Binding Sites; Bisbenzimidazole; Diminazene; Distamycins; DNA; Ligands; Molecular Sequence Data; Netropsin; Nucleic Acid Conformation; Structure-Activity Relationship

1995
Selective toxicity to malaria parasites by non-intercalating DNA-binding ligands.
    Molecular and biochemical parasitology, 1993, Volume: 58, Issue:1

    Topics: Animals; Base Composition; Bisbenzimidazole; Cell Division; Cells, Cultured; Chromomycins; Distamycins; DNA, Protozoan; Dose-Response Relationship, Drug; Humans; Indoles; Intercalating Agents; Mice; Netropsin; Nucleic Acid Conformation; Plasmodium falciparum; Plicamycin; Saccharomyces cerevisiae

1993
The binding mode of drugs to the TAR RNA of HIV-1 studied by electric linear dichroism.
    Nucleic acids research, 1996, Apr-15, Volume: 24, Issue:8

    Topics: Antiviral Agents; Bisbenzimidazole; Diminazene; Ethidium; HIV Long Terminal Repeat; HIV-1; Humans; Indoles; Intercalating Agents; Molecular Sequence Data; Netropsin; Nucleic Acid Conformation; Proflavine; RNA, Viral; Spectrum Analysis

1996
Minor groove binding ligands alter the rotational positioning of DNA fragments on nucleosome core particles.
    Journal of molecular biology, 1996, Oct-11, Volume: 262, Issue:5

    Topics: Base Composition; Base Sequence; Bisbenzimidazole; Deoxyribonuclease I; Diminazene; Distamycins; DNA Footprinting; DNA, Bacterial; Hydroxyl Radical; Ligands; Molecular Sequence Data; Netropsin; Nucleic Acid Conformation; Nucleosomes; Plasmids

1996
Linked lexitropsins and the in vitro inhibition of HIV-1 reverse transcriptase RNA-directed DNA polymerization: a novel induced-fit of 3,5 m-pyridyl bisdistamycin to enzyme-associated template-primer.
    Biochemistry, 1996, Dec-03, Volume: 35, Issue:48

    Topics: Antiviral Agents; Bisbenzimidazole; Diminazene; Distamycins; DNA Polymerase I; DNA Primers; Electrophoresis, Polyacrylamide Gel; HIV Reverse Transcriptase; Indoles; Kinetics; Models, Molecular; Netropsin; RNA-Directed DNA Polymerase; Templates, Genetic; Thymine Nucleotides

1996
Multimode interaction of Hoechst 33258 with eukaryotic DNA; quantitative analysis of the DNA conformational changes.
    Journal of biomolecular structure & dynamics, 1998, Volume: 15, Issue:4

    Topics: Animals; Bisbenzimidazole; Cattle; DNA; Ligands; Netropsin; Nucleic Acid Conformation; Viscosity

1998
Use of capillary electrophoresis in the study of ligand-DNA interactions.
    Nucleic acids research, 1998, Jun-15, Volume: 26, Issue:12

    Topics: Binding, Competitive; Bisbenzimidazole; Dactinomycin; Distamycins; DNA; Electrophoresis, Capillary; Ethidium; Intercalating Agents; Ligands; Netropsin; Nucleic Acid Conformation; Oligodeoxyribonucleotides

1998
Electrostatic contributions to heat capacity changes of DNA-ligand binding.
    Biophysical journal, 1998, Volume: 75, Issue:2

    Topics: Antineoplastic Agents; Binding Sites; Bisbenzimidazole; DNA; DNA-Binding Proteins; Hot Temperature; Indoles; Intercalating Agents; Ligands; Models, Chemical; Netropsin; Repressor Proteins; Static Electricity; Thermodynamics; Viral Proteins; Viral Regulatory and Accessory Proteins

1998
Specific molecular recognition of mixed nucleic acid sequences: an aromatic dication that binds in the DNA minor groove as a dimer.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Jan-04, Volume: 97, Issue:1

    Topics: Amidines; Base Sequence; Bisbenzimidazole; Dimerization; DNA; DNA Footprinting; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Netropsin; Surface Plasmon Resonance

2000
Ligand binding to oligonucleotides.
    Methods in molecular biology (Clifton, N.J.), 2001, Volume: 163

    Topics: Antiviral Agents; Bisbenzimidazole; Dactinomycin; Distamycins; DNA; Electrophoresis, Capillary; Ethidium; Fluorescent Dyes; Hydrogen-Ion Concentration; Intercalating Agents; Ligands; Molecular Structure; Netropsin; Nucleic Acid Synthesis Inhibitors; Oligonucleotides

2001
A simple, high-resolution method for establishing DNA binding affinity and sequence selectivity.
    Journal of the American Chemical Society, 2001, Jun-27, Volume: 123, Issue:25

    Topics: Base Pairing; Base Sequence; Binding Sites; Bisbenzimidazole; Distamycins; DNA; Fluorescent Dyes; Indoles; Netropsin; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Robotics; Sequence Analysis, DNA; Structure-Activity Relationship

2001
Significance of ligand tails for interaction with the minor groove of B-DNA.
    Biophysical journal, 2001, Volume: 81, Issue:3

    Topics: Base Sequence; Bisbenzimidazole; Computer Simulation; DNA; Ligands; Models, Molecular; Netropsin; Nucleic Acid Conformation; Oligonucleotides; Piperazine; Piperazines

2001
Synergistic induction of the senescence-associated genes by 5-bromodeoxyuridine and AT-binding ligands in HeLa cells.
    Experimental cell research, 2002, Jun-10, Volume: 276, Issue:2

    Topics: Antiviral Agents; AT Rich Sequence; Bisbenzimidazole; Bromodeoxyuridine; Bromouracil; Cell Division; Cellular Senescence; Chromosome Mapping; Distamycins; DNA; Dose-Response Relationship, Drug; Eukaryotic Cells; Fluorescent Dyes; Gene Expression Regulation; Genes; HeLa Cells; Humans; Netropsin; Nuclear Matrix; Nuclear Proteins; Protein Binding; RNA, Messenger

2002
Aromatic analogues of DNA minor groove binders--synthesis and biological evaluation.
    European journal of medicinal chemistry, 2004, Volume: 39, Issue:1

    Topics: Antineoplastic Agents; Bisbenzimidazole; Cell Division; Cell Line, Tumor; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Humans; Ligands; Molecular Structure; Netropsin; Pentamidine; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

2004
Nature of minor-groove binders-DNA complexes in the gas phase.
    Journal of the American Chemical Society, 2005, Aug-24, Volume: 127, Issue:33

    Topics: Binding Sites; Bisbenzimidazole; Computer Simulation; DNA; Gases; Indoles; Molecular Structure; Netropsin; Structure-Activity Relationship; Thermodynamics; Water

2005
Structural studies on ligand-DNA systems: A robust approach in drug design.
    Journal of biosciences, 2012, Volume: 37, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Antiviral Agents; Base Sequence; Benzoxazoles; Berberine; Bisbenzimidazole; Butyrates; Drug Design; Hydrogen Bonding; Imidazoles; Indoleacetic Acids; Ligands; Molecular Dynamics Simulation; Netropsin; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Plasmids; Vincristine

2012