Compounds > bisaramil
Page last updated: 2024-09-04

bisaramil and flecainide

bisaramil has been researched along with flecainide in 4 studies

Compound Research Comparison

Studies
(bisaramil)		Trials
(bisaramil)		Recent Studies (post-2010)
(bisaramil)		Studies
(flecainide)		Trials
(flecainide)		Recent Studies (post-2010) (flecainide)
22111,881229490

Protein Interaction Comparison

ProteinTaxonomybisaramil (IC50)flecainide (IC50)
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)3.8905
Sodium channel protein type 5 subunit alphaHomo sapiens (human)6.5

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Sugimoto, T; Yamashita, T1
Haruno, A; Hashimoto, K1
Haruno, A; Hashimoto, K; Sugiyama, A1

Other Studies

4 other study(ies) available for bisaramil and flecainide

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
[Medical management of arrhythmias; newer antiarrhythmic drugs].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:11

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Calcium Channel Blockers; Chlorobenzenes; Flecainide; Humans; Membrane Potentials; Moricizine; Piperidines; Propylamines; Pyridines; Sodium Channels

1991
Antiarrhythmic effects of bisaramil on triggered arrhythmias produced by intracoronary injection of digitalis and adrenaline in the dog.
    Japanese journal of pharmacology, 1995, Volume: 68, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bridged Bicyclo Compounds, Heterocyclic; Chlorobenzenes; Digitalis Glycosides; Disease Models, Animal; Disopyramide; Dogs; Epinephrine; Female; Flecainide; Injections, Intra-Arterial; Lidocaine; Male; Ouabain; Verapamil

1995
Chronotropic, inotropic, dromotropic and coronary vasodilator effects of bisaramil, a new class I antiarrhythmic drug, assessed using canine isolated, blood-perfused heart preparations.
    Japanese journal of pharmacology, 1999, Volume: 80, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Blood Flow Velocity; Bridged Bicyclo Compounds, Heterocyclic; Chlorobenzenes; Coronary Vessels; Disopyramide; Dogs; Female; Flecainide; Heart; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Reperfusion; Sinoatrial Node; Vasodilation

1999