bis(4-piperidinophenol)diimidonaphthalene-1,4,5,8-tetracarboxylic acid dibenzosulfoethylate and piperidines

bis(4-piperidinophenol)diimidonaphthalene-1,4,5,8-tetracarboxylic acid dibenzosulfoethylate has been researched along with piperidines in 38 studies

Compound Research Comparison

Studies (bis(4-piperidinophenol)diimidonaphthalene-1,4,5,8-tetracarboxylic acid dibenzosulfoethylate)	Trials (bis(4-piperidinophenol)diimidonaphthalene-1,4,5,8-tetracarboxylic acid dibenzosulfoethylate)	Recent Studies (post-2010) (bis(4-piperidinophenol)diimidonaphthalene-1,4,5,8-tetracarboxylic acid dibenzosulfoethylate)	Studies (piperidines)	Trials (piperidines)	Recent Studies (post-2010) (piperidines)
40	1	2	40,235	5,221	14,545

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.63)	18.7374
1990's	3 (7.89)	18.2507
2000's	31 (81.58)	29.6817
2010's	3 (7.89)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Danilov, AF; Dorofeeva, NA; Nedoma, J; Shelkovnikov, SA; Tucek, S	1
Belanger, A; Gauthier, S; Labrie, C; Labrie, F; Merand, Y; Poirier, D; Sanchez, R; Simard, J; Singh, SM	1
Jordan, VC; Liu, H; Schafer, JI; Tonetti, DA	1
Jeannin, E; Liu, JW; Picard, D	1
Bélanger, A; Deshaies, Y; Labrie, C; Labrie, F; Lalonde, J; Picard, F; Richard, D; Samson, P	1
Albert, C; Barbier, O; Bélanger, A; High, K; Hum, DW; Labrie, C; Labrie, F; Martineau, I; Vallée, M	1
Labrie, C; Labrie, F; Li, S; Martel, C; Pelletier, G	1
El-Alfy, M; Labrie, C; Labrie, F; Martel, C; Pelletier, G	1
Bélanger, A; Giguère, V; Labrie, C; Labrie, F; Simard, J; Tremblay, A; Tremblay, G	1
Gajdos, C; Jordan, VC	1
Elkak, AE; Mokbel, K	1
Candas, B; Couillard, S; Gutman, M; Labrie, C; Labrie, F; Roy, J	1
Bernardi, F; Labrie, F; Luisi, S; Pieri, M; Riccardo Genazzani, A; Stomati, M	1
Fornari, L; Genazzani, AR; Labrie, F; Luisi, M; Mannella, P; Simoncini, T; Varone, G	1
Cano, A; García-Martínez, MC; Hermenegildo, C; Tarín, JJ	1
Bai, Y; Giguére, V	1
Labrie, F; Marette, A; Martel, C; Tatchum-Talom, R	1
Deshaies, Y; Labrie, F; Lemieux, C; Picard, F; Richard, D	1
Briand, P; Jensen, J; Kitlen, JW; Labrie, F; Lykkesfeldt, AE	1
Bélanger, A; Berger, L; Candas, B; El-Alfy, M; Labrie, C; Labrie, F; Martel, C; Pelletier, G	1
Hoffman, GE; Zup, SL	1
Couillard, S; Gutman, M; Labrie, F; Roy, J	1
Basrur, V; Rowan, BG; Shah, YM	1
Cheung, AM; Goss, PE; Hu, H; Mendes, M; Pritzker, KP; Qi, S	1
Bolton, JL; Liu, H; Liu, J; Thatcher, GR; van Breemen, RB	1
Cianflone, K; Deshaies, Y; Gélinas, Y; Labrie, F; Lalonde, J; Lemieux, C	1
Deshaies, Y; Giguère, V; Labrie, F; Lemieux, C; Phaneuf, D; Richard, D	1
Cloutier, J; Dory, YL; Favre, A; Gauthier, S; Labrie, F; Mailhot, J; Martel, C; Mérand, Y; Ouellet, C; Schwerdtfeger, A; Simard, J	1
Berger, L; El-Alfy, M; Labrie, F; Martel, C	1
Deshaies, Y; Gélinas, Y; Labrie, F; Lalonde, J; Lemieux, C; Richard, D	2
Al-Dhaheri, MH; Basrur, V; Pind, S; Rowan, BG; Shah, YM	1
Brown, P; Kim, H; Krajewski, S; Labrie, F; Lamph, W; Liby, K; Rendi, M; Risingsong, R; Royce, DB; Sporn, MB; Suh, N; Williams, CR; Xu, X	1
Griekspoor, A; Michalides, R; Neefjes, J; Rondaij, M; Verwoerd, D; Zwart, W	1
Shao, ZM; Yu, KD	1
Amisten, S; Balhuizen, A; Kumar, R; Lundquist, I; Salehi, A	1
Belleau, P; Calvo, E; Labrie, F; Luu-The, V; Martel, C	1
Bailey, HH; Fabian, CJ; Havighurst, TC; Heckman-Stoddard, BM; Kim, K; Kimler, BF; Metheny, T; Petroff, BK; Phillips, TA; Zalles, CM	1

Reviews

4 review(s) available for bis(4-piperidinophenol)diimidonaphthalene-1,4,5,8-tetracarboxylic acid dibenzosulfoethylate and piperidines

Article	Year
EM-652 (SCH57068), a pure SERM having complete antiestrogenic activity in the mammary gland and endometrium. The Journal of steroid biochemistry and molecular biology, 2001, Volume: 79, Issue:1-5 Topics: Animals; Benzopyrans; Breast; Breast Neoplasms; Cholesterol; Endometrial Neoplasms; Endometrium; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Female; Humans; Mammary Neoplasms, Experimental; Mice; Neoplasms, Hormone-Dependent; Osteoporosis; Piperidines; Propionates; Rats; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Transcription, Genetic; Triglycerides; Tumor Cells, Cultured	2001
Selective estrogen receptor modulators as a new therapeutic drug group: concept to reality in a decade. Clinical breast cancer, 2002, Volume: 2, Issue:4 Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cinnamates; Drug Design; Forecasting; Humans; Molecular Biology; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Stilbenes; Tamoxifen; Tetrahydronaphthalenes; Thiophenes; Toremifene; Treatment Outcome	2002
Pure antiestrogens and breast cancer. Current medical research and opinion, 2001, Volume: 17, Issue:4 Topics: Antineoplastic Agents, Hormonal; Benzopyrans; Breast Neoplasms; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Piperidines; Polyunsaturated Alkamides; Propionates	2001
Good versus evil: changing the approach to hormone replacement therapy. Endocrinology, 2003, Volume: 144, Issue:11 Topics: Animals; Estradiol; Estrogen Replacement Therapy; Humans; Piperidines; Selective Estrogen Receptor Modulators	2003

Trials

1 trial(s) available for bis(4-piperidinophenol)diimidonaphthalene-1,4,5,8-tetracarboxylic acid dibenzosulfoethylate and piperidines

Article	Year
Clinical Trial of Acolbifene in Premenopausal Women at High Risk for Breast Cancer. Cancer prevention research (Philadelphia, Pa.), 2015, Volume: 8, Issue:12 Topics: Adult; Biopsy, Fine-Needle; Bone Density; Breast; Breast Neoplasms; Cell Proliferation; Epithelial Cells; Female; Humans; Ki-67 Antigen; Middle Aged; Ovarian Cysts; Pilot Projects; Piperidines; Premenopause; Real-Time Polymerase Chain Reaction; Risk Factors; Selective Estrogen Receptor Modulators; Transcriptome	2015

Article

Year

Clinical Trial of Acolbifene in Premenopausal Women at High Risk for Breast Cancer.

Cancer prevention research (Philadelphia, Pa.), 2015, Volume: 8, Issue:12

Topics: Adult; Biopsy, Fine-Needle; Bone Density; Breast; Breast Neoplasms; Cell Proliferation; Epithelial Cells; Female; Humans; Ki-67 Antigen; Middle Aged; Ovarian Cysts; Pilot Projects; Piperidines; Premenopause; Real-Time Polymerase Chain Reaction; Risk Factors; Selective Estrogen Receptor Modulators; Transcriptome

2015

Other Studies

33 other study(ies) available for bis(4-piperidinophenol)diimidonaphthalene-1,4,5,8-tetracarboxylic acid dibenzosulfoethylate and piperidines

Article	Year
Interaction of the neuromuscular blocking drugs alcuronium, decamethonium, gallamine, pancuronium, ritebronium, tercuronium and d-tubocurarine with muscarinic acetylcholine receptors in the heart and ileum. Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 329, Issue:2 Topics: Alcuronium; Animals; Binding, Competitive; Decamethonium Compounds; Female; Gallamine Triethiodide; Heart; Ileum; In Vitro Techniques; Kinetics; Muscle, Smooth; Myocardium; Neuromuscular Blocking Agents; Pancuronium; Piperidines; Quaternary Ammonium Compounds; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Tubocurarine	1985
Blockade of the stimulatory effect of estrogens, OH-tamoxifen, OH-toremifene, droloxifene, and raloxifene on alkaline phosphatase activity by the antiestrogen EM-800 in human endometrial adenocarcinoma Ishikawa cells. Cancer research, 1997, Aug-15, Volume: 57, Issue:16 Topics: Adenocarcinoma; Alkaline Phosphatase; Benzopyrans; Endometrial Neoplasms; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Neoplasm Proteins; Piperidines; Propionates; Raloxifene Hydrochloride; Tamoxifen; Toremifene; Tumor Cells, Cultured	1997
The interaction of raloxifene and the active metabolite of the antiestrogen EM-800 (SC 5705) with the human estrogen receptor. Cancer research, 1999, Sep-01, Volume: 59, Issue:17 Topics: Benzopyrans; Cell Division; Estradiol; Estrogen Antagonists; Fulvestrant; Humans; Piperidines; Propionates; Raloxifene Hydrochloride; Receptors, Estrogen; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	1999
The anti-estrogen hydroxytamoxifen is a potent antagonist in a novel yeast system. Biological chemistry, 1999, Volume: 380, Issue:11 Topics: Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Humans; Indoles; Nafoxidine; Piperidines; Polyunsaturated Alkamides; Receptors, Estrogen; Saccharomyces cerevisiae; Sulfones; Tamoxifen; Two-Hybrid System Techniques	1999
Effects of the estrogen antagonist EM-652.HCl on energy balance and lipid metabolism in ovariectomized rats. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2000, Volume: 24, Issue:7 Topics: Animals; Cardiovascular Diseases; Disease Models, Animal; Energy Metabolism; Estrogen Antagonists; Female; Hyperlipidemias; Insulin Resistance; Lipid Metabolism; Obesity; Ovariectomy; Piperidines; Rats; Rats, Sprague-Dawley; Risk Factors; Selective Estrogen Receptor Modulators	2000
Glucuronidation of the nonsteroidal antiestrogen EM-652 (SCH 57068), by human and monkey steroid conjugating UDP-glucuronosyltransferase enzymes. Molecular pharmacology, 2001, Volume: 59, Issue:3 Topics: Animals; Cells, Cultured; Estrogen Receptor Modulators; Female; Glucuronates; Glucuronosyltransferase; Haplorhini; Humans; Male; Microsomes, Liver; Piperidines; Rats; Rats, Sprague-Dawley; Steroids	2001
Role of extra-ovarian oestrogens in the regulation of gonadotropin releasing hormone mRNA expression in the rat brain. Journal of neuroendocrinology, 2001, Volume: 13, Issue:8 Topics: Animals; Autoradiography; Estrogen Receptor Modulators; Estrogens; Feedback; Female; Gene Expression; Gonadotropin-Releasing Hormone; Ovariectomy; Ovary; Piperidines; Preoptic Area; Rats; Rats, Sprague-Dawley; RNA, Messenger	2001
Effect of long-term treatment with the antiestrogen EM-652.HCl on pituitary estrogen receptor alpha and prolactin mRNA expression in intact, ovariectomized and gonadotropin-releasing hormone-treated female rats. Neuroendocrinology, 2001, Volume: 74, Issue:6 Topics: Animals; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Gonadotropin-Releasing Hormone; Ovariectomy; Piperidines; Pituitary Gland; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Reference Values; RNA, Messenger; Time Factors	2001
Comparison of the effects of EM-652 (SCH57068), tamoxifen, toremifene, droloxifene, idoxifene, GW-5638 and raloxifene on the growth of human ZR-75-1 breast tumors in nude mice. International journal of cancer, 2002, May-10, Volume: 99, Issue:2 Topics: Animals; Breast Neoplasms; Cell Division; Cell Size; Cinnamates; Endometrium; Epithelial Cells; Estrogen Antagonists; Estrone; Female; Humans; Kinetics; Mice; Mice, Nude; Neoplasm Transplantation; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Stilbenes; Tamoxifen; Toremifene; Tumor Cells, Cultured	2002
Effects of the new generation selective estrogen receptor modulator EM-652 and oral administration of estradiol valerate on circulating, brain, and adrenal beta-endorphin and allopregnanolone levels in intact fertile and ovariectomized rats. Fertility and sterility, 2002, Volume: 77, Issue:5 Topics: Administration, Oral; Adrenal Glands; Animals; beta-Endorphin; Brain; Drug Synergism; Estradiol; Female; Fertility; Hippocampus; Hypothalamus; Ovariectomy; Piperidines; Pituitary Gland; Pregnanolone; Rats; Rats, Wistar; Selective Estrogen Receptor Modulators	2002
Genomic and nongenomic mechanisms of nitric oxide synthesis induction in human endothelial cells by a fourth-generation selective estrogen receptor modulator. Endocrinology, 2002, Volume: 143, Issue:6 Topics: Animals; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Enzyme Activators; Female; Humans; Immunoblotting; Mitogen-Activated Protein Kinases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Ovariectomy; Piperidines; Pregnancy; Rats; Rats, Wistar; Selective Estrogen Receptor Modulators	2002
Estradiol reduces F2alpha-isoprostane production in cultured human endothelial cells. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:6 Topics: Cells, Cultured; Culture Media, Conditioned; Dose-Response Relationship, Drug; Endothelium, Vascular; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Infant, Newborn; Isoprostanes; Male; Medroxyprogesterone Acetate; Piperidines; Progesterone; Progesterone Congeners; Umbilical Veins	2002
Isoform-selective interactions between estrogen receptors and steroid receptor coactivators promoted by estradiol and ErbB-2 signaling in living cells. Molecular endocrinology (Baltimore, Md.), 2003, Volume: 17, Issue:4 Topics: Acetyltransferases; Bacterial Proteins; Cells, Cultured; Dimerization; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; Histone Acetyltransferases; Humans; Luminescent Proteins; Mutation; Nuclear Receptor Coactivator 1; Nuclear Receptor Coactivator 3; Oncogene Proteins; Piperidines; Protein Isoforms; Protein Structure, Tertiary; Receptor, ErbB-2; Receptors, Estrogen; Recombinant Proteins; Signal Transduction; Tamoxifen; Trans-Activators; Transcription Factors	2003
Acute vascular effects of the selective estrogen receptor modulator EM-652 (SCH 57068) in the rat mesenteric vascular bed. Cardiovascular research, 2003, Volume: 57, Issue:2 Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Estradiol; Female; Male; Methoxamine; Nitric Oxide; Piperidines; Potassium Channels; Rats; Reactive Oxygen Species; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Splanchnic Circulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents	2003
The estrogen antagonist EM-652 and dehydroepiandrosterone prevent diet- and ovariectomy-induced obesity. Obesity research, 2003, Volume: 11, Issue:3 Topics: Adipose Tissue; Animals; Body Composition; Body Weight; Cholesterol; Dehydroepiandrosterone; Diet; Dietary Fats; Dietary Sucrose; Eating; Energy Intake; Energy Metabolism; Estrogen Antagonists; Female; Insulin Resistance; Lipoprotein Lipase; Liver; Obesity; Ovariectomy; Piperidines; Rats; Rats, Sprague-Dawley; Triglycerides; Weight Gain	2003
Effect of antiestrogens and aromatase inhibitor on basal growth of the human breast cancer cell line MCF-7 in serum-free medium. The Journal of steroid biochemistry and molecular biology, 2003, Volume: 84, Issue:4 Topics: Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Blotting, Northern; Blotting, Western; Breast Neoplasms; Cell Division; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Fulvestrant; Humans; Ligands; Membrane Proteins; Piperidines; Presenilin-2; Protein Binding; Receptors, Estrogen; RNA, Messenger; Tamoxifen; Time Factors; Tumor Cells, Cultured	2003
The combination of a novel selective estrogen receptor modulator with an estrogen protects the mammary gland and uterus in a rodent model: the future of postmenopausal women's health? Endocrinology, 2003, Volume: 144, Issue:11 Topics: Animals; Bone Density; Brain; Cholesterol; Drug Combinations; Estradiol; Estrogen Receptor alpha; Estrogen Replacement Therapy; Female; Humans; Mammary Glands, Animal; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Uterus	2003
A novel pure SERM achieves complete regression of the majority of human breast cancer tumors in nude mice. Breast cancer research and treatment, 2003, Volume: 81, Issue:3 Topics: Analysis of Variance; Animals; Breast Neoplasms; Carcinoma; Estrogens, Non-Steroidal; Female; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Piperidines; Recurrence; Remission Induction; Selective Estrogen Receptor Modulators	2003
Selective estrogen receptor modulator regulated proteins in endometrial cancer cells. Molecular and cellular endocrinology, 2004, Apr-30, Volume: 219, Issue:1-2 Topics: Biomarkers; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Endometrial Neoplasms; Estradiol; Female; Heterogeneous-Nuclear Ribonucleoprotein Group F-H; HSP90 Heat-Shock Proteins; Humans; Keratins; Lactoferrin; Neoplasm Proteins; Phosphoproteins; Piperidines; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Ubiquitin-Conjugating Enzymes	2004
The selective estrogen receptor modulator SCH 57068 prevents bone loss, reduces serum cholesterol and blocks estrogen-induced uterine hypertrophy in ovariectomized rats. The Journal of steroid biochemistry and molecular biology, 2004, Volume: 92, Issue:1-2 Topics: Animals; Biomarkers; Biomechanical Phenomena; Bone Density; Cholesterol; Disease Models, Animal; Estrogen Antagonists; Estrogens; Female; Femur; Hypertrophy; Lumbar Vertebrae; Molecular Structure; Organ Size; Osteoporosis; Ovariectomy; Piperidines; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Uterus; Weight Gain	2004
Bioactivation of the selective estrogen receptor modulator acolbifene to quinone methides. Chemical research in toxicology, 2005, Volume: 18, Issue:2 Topics: Animals; Biotransformation; Breast Neoplasms; Cell Line, Tumor; DNA Damage; Female; Glutathione; Humans; Indolequinones; Kinetics; Microsomes, Liver; Molecular Structure; Oligodeoxyribonucleotides; Oxidation-Reduction; Piperidines; Rats; Selective Estrogen Receptor Modulators	2005
Hypolipidemic action of the SERM acolbifene is associated with decreased liver MTP and increased SR-BI and LDL receptors. Journal of lipid research, 2005, Volume: 46, Issue:6 Topics: Animals; Blotting, Western; Carrier Proteins; CCAAT-Enhancer-Binding Proteins; CD36 Antigens; Cholesterol; DNA-Binding Proteins; Female; Food Deprivation; Hydroxymethylglutaryl CoA Reductases; Kinetics; Lipid Metabolism; Liver; Piperidines; PPAR alpha; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, LDL; Receptors, Scavenger; RNA, Messenger; Scavenger Receptors, Class B; Selective Estrogen Receptor Modulators; Sterol Regulatory Element Binding Protein 1; Time Factors; Transcription Factors; Triglycerides	2005
Estrogen receptor alpha-mediated adiposity-lowering and hypocholesterolemic actions of the selective estrogen receptor modulator acolbifene. International journal of obesity (2005), 2005, Volume: 29, Issue:10 Topics: Adiposity; Animals; Cholesterol; Estrogen Receptor alpha; Female; Liver; Male; Mice; Mice, Inbred C57BL; Piperidines; Random Allocation; Selective Estrogen Receptor Modulators; Triglycerides	2005
Synthesis and structure-activity relationships of analogs of EM-652 (acolbifene), a pure selective estrogen receptor modulator. Study of nitrogen substitution. Journal of enzyme inhibition and medicinal chemistry, 2005, Volume: 20, Issue:2 Topics: Animals; Benzopyrans; Cattle; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Enzyme Inhibitors; Estrogen Receptor Modulators; Estrogens; Female; Humans; Inhibitory Concentration 50; Insulin; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Models, Chemical; Nitrogen; Piperidines; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Structure-Activity Relationship	2005
Effects of dehydroepiandrosterone, Premarin and Acolbifene on histomorphology and sex steroid receptors in the rat vagina. The Journal of steroid biochemistry and molecular biology, 2005, Volume: 96, Issue:2 Topics: Animals; Dehydroepiandrosterone; Estrogens, Conjugated (USP); Estrus; Female; In Vitro Techniques; Organ Size; Ovariectomy; Piperidines; Proestrus; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Vagina	2005
The selective estrogen receptor modulator acolbifene reduces cholesterolemia independently of its anorectic action in control and cholesterol-fed rats. The Journal of nutrition, 2005, Volume: 135, Issue:9 Topics: Animals; Anorexia; Cholesterol; Cholesterol, Dietary; Female; Hypercholesterolemia; Liver; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, LDL; Scavenger Receptors, Class B; Selective Estrogen Receptor Modulators	2005
Hypocholesterolemic action of the selective estrogen receptor modulator acolbifene in intact and ovariectomized rats with diet-induced hypercholesterolemia. Metabolism: clinical and experimental, 2006, Volume: 55, Issue:5 Topics: Animals; ATP-Binding Cassette Transporters; Blood Glucose; Cholesterol, Dietary; Female; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Liver; Ovariectomy; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, LDL; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selective Estrogen Receptor Modulators; Statistics, Nonparametric; Sterol Regulatory Element Binding Proteins; Weight Gain	2006
Identification of novel proteins induced by estradiol, 4-hydroxytamoxifen and acolbifene in T47D breast cancer cells. Steroids, 2006, Volume: 71, Issue:11-12 Topics: Amino Acid Sequence; Breast Neoplasms; Cell Line, Tumor; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Female; Humans; Molecular Sequence Data; Neoplasm Proteins; Piperidines; Tamoxifen	2006
The combination of the rexinoid, LG100268, and a selective estrogen receptor modulator, either arzoxifene or acolbifene, synergizes in the prevention and treatment of mammary tumors in an estrogen receptor-negative model of breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Oct-01, Volume: 12, Issue:19 Topics: Animals; Cell Division; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Nicotinic Acids; Piperidines; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Survival Rate; Tetrahydronaphthalenes; Thiophenes	2006
Classification of anti-estrogens according to intramolecular FRET effects on phospho-mutants of estrogen receptor alpha. Molecular cancer therapeutics, 2007, Volume: 6, Issue:5 Topics: Bacterial Proteins; Cell Line, Tumor; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogens; Fluorescence Resonance Energy Transfer; Fulvestrant; Humans; Luminescent Proteins; Models, Biological; Models, Chemical; Mutation; Piperidines; Tamoxifen; Transcriptional Activation	2007
Concurrent hormone and radiation therapy in patients with breast cancer: how does chemotherapy affect treatment? The Lancet. Oncology, 2009, Volume: 10, Issue:5 Topics: Animals; Aromatase Inhibitors; Breast Neoplasms; Combined Modality Therapy; Estrogen Antagonists; Female; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Piperidines	2009
Activation of G protein-coupled receptor 30 modulates hormone secretion and counteracts cytokine-induced apoptosis in pancreatic islets of female mice. Molecular and cellular endocrinology, 2010, May-14, Volume: 320, Issue:1-2 Topics: Animals; Apoptosis; Cyclic AMP; Cytokines; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fulvestrant; Gene Expression Regulation; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Pancreatic Hormones; Piperidines; Receptors, Estrogen; Receptors, G-Protein-Coupled; RNA, Messenger	2010
Specific transcriptional response of four blockers of estrogen receptors on estradiol-modulated genes in the mouse mammary gland. Breast cancer research and treatment, 2012, Volume: 134, Issue:2 Topics: Animals; Cluster Analysis; Estradiol; Estrogen Antagonists; Estrogens; Female; Fulvestrant; Gene Expression Regulation; Genes; Genes, Neoplasm; Mammary Glands, Animal; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Receptors, Estrogen; Tamoxifen; Transcription, Genetic; Transcriptome	2012