bis(4-nitrophenyl)phosphate has been researched along with nitrophenols in 127 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (22.83) | 18.7374 |
| 1990's | 24 (18.90) | 18.2507 |
| 2000's | 37 (29.13) | 29.6817 |
| 2010's | 33 (25.98) | 24.3611 |
| 2020's | 4 (3.15) | 2.80 |
| Authors | Studies |
|---|---|
| Heymann, E; Mentlein, R; Schmalz, R; Schwabe, C; Wagenmann, F | 1 |
| Ronai, A; Trefzger, J; von Deimling, O; Wassmer, B | 1 |
| Alcedo, JA; Bement, WJ; Hamilton, JW; Sinclair, JF; Sinclair, PR; Wetterhahn, KE | 1 |
| Bogdanffy, MS; Trela, BA | 2 |
| Bartolone, JB; Beierschmitt, WP; Cohen, SD; Emeigh Hart, SG; Khairallah, EA; Wyand, DS | 1 |
| Monteith, DK; Strom, SC | 1 |
| Morris, JB | 2 |
| Hanna, PE; Wick, MJ | 1 |
| Jakoby, WB; Kim, DH; Yang, YS | 1 |
| Crisp, M; Ellis, G; Hawley, DM; Hodes, ME; Hodes, MZ; Karn, RC | 1 |
| McGirr, LG; O'Brien, PJ; Rossi, L; Silva, J | 1 |
| Augenstein, U; de Looze, S; Ronai, A; von Deimling, O; Wassmer, B | 2 |
| von Deimling, OH | 1 |
| Lai, CC; Liem, A; Miller, EC; Miller, JA | 1 |
| Eggermont, J; Hope, DB; White, KN | 1 |
| Caesar, R; Frank, N; Scherf, HR; Wiessler, M | 1 |
| Allen, DT; Johnston, CT; Marks, GS; Nakatsu, K; Sutherland, EP; Whitney, RA | 1 |
| Ahtee, L; Auvinen, H; Halmekoski, J; Lehtinen, M; Mäenpää, AR; Vahala, ML | 1 |
| Bernstein, J; DeShone, GM; Hoefle, D; Hook, JB; Kuo, CH; Newton, JF | 1 |
| Hagner, G; Huhn, D; Kastner, M; Oertel, J | 1 |
| Yoshida, H | 1 |
| Hawley, DM; Hodes, ME; Schulz, AR | 1 |
| Heymann, E; Mentlein, R; Schumann, M | 1 |
| Cacan, R; Guette, F; Montreuil, J; Verbert, A | 1 |
| Mellors, A; Werchola, GM | 1 |
| Nousiainen, U | 1 |
| Hope, DB; White, KN | 2 |
| Nousiainen, U; Törrönen, R | 1 |
| Kastner, M; Oertel, J | 1 |
| Mitchell, JR; Nelson, SD; Snodgrass, WR; Timbrell, JA | 1 |
| Burchell, B; Odell, GB | 1 |
| Otto, J; von Deimling, OH | 1 |
| Bourget, L; Chéné, L; Gagnon, C; Vinay, P | 1 |
| Cacan, R; Hoflack, B; Verbert, A | 1 |
| Heymann, E; Mentlein, R | 1 |
| Ganzhorn, AJ; Pelton, PD; Strasser, F | 1 |
| Mugford, CA; Tarloff, JB | 1 |
| Derewlany, LO; Koren, G | 1 |
| Beer, D; Beer, M; Gasser, R; Jenö, P; Meyer, UA; Probst, MR | 1 |
| Hemingway, J; Jayawardena, KG; Karunaratne, SH; Ketterman, AJ | 1 |
| Bogdanffy, MS; Kuykendall, JR; Taylor, ML | 1 |
| Heymann, E; Hoppe, W; Krüsselmann, A; Tschoetschel, C | 1 |
| Bisesi, MS; Park, SC; Smith, TJ | 1 |
| Pavković, E; Radić, Z; Reiner, E; Simeon, V | 1 |
| Alexson, SE; Björkhem, I; Diczfalusy, MA; Einarsson, K | 1 |
| Andersen, ME; Bogdanffy, MS; Plowchalk, DR | 1 |
| Ishiguro, I; Nishida, K; Ohta, Y | 1 |
| Bourland, JA; Martin, DK; Mayersohn, M | 1 |
| Adams, SP; Petricca, G; Sarich, TC; Wright, JM | 1 |
| Bogdanffy, MS; Manning, LA; Sarangapani, R | 1 |
| Nagy, A; Plonowski, A; Schally, AV | 1 |
| Lagunavicius, A; Lubys, A; Sapranauskas, R; Sasnauskas, G; Siksnys, V; Vilkaitis, G | 1 |
| Bencini, A; Bianchi, A; Chand, DK; Ciattini, S; Giorgi, C; Schneider, HJ; Valtancoli, B | 1 |
| Foster, JR; Green, T; Lund, V; Mainwaring, G | 1 |
| Herschlag, D; O'Brien, PJ | 1 |
| Brück, W; Engelke, S; Maruschak, B; Siebert, H | 1 |
| Breslow, R; Leivers, M | 1 |
| Burstyn, JN; Deck, KM; Tseng, TA | 1 |
| Bogdanffy, MS | 1 |
| Keasling, JD; Tehara, SK | 1 |
| Bogdanffy, MS; Lantz, RC; Orozco, J | 1 |
| Chiba, K; Hosokawa, M; Imai, T; Otagiri, M; Yoshigae, Y | 1 |
| Canary, JW; dos Santos, O; Koo, CW; Pape, L; Rybstein, M; Zhu, L | 1 |
| Anderson, K; Atkinson, J; Kline, K; Lawson, KA; Sanders, BG; Simmons-Menchaca, M | 1 |
| Agrawal, AK; Chen, Z; Chiu, SH; Franklin, RB; Leung, KH | 1 |
| Meyer-Klaucke, W; Schilling, O; Vogel, A | 1 |
| Imamura, S; Katsuyama, T; Kawasaki, K; Nomoto, S; Soya, H; Sugano, K; Sugano, M; Tanaka, T; Tozuka, M; Yamauchi, K | 1 |
| Bobrov, AG; Kirillina, O; Perry, RD | 1 |
| Gao, J; Simon, M | 1 |
| Funahashi, T; Kimura, T; Matsunaga, T; Shoyama, Y; Watanabe, K; Yamamoto, I; Yamaori, S | 1 |
| Chang, CA; Kuan, BY; Wu, BH | 1 |
| Andrievsky, A; Chin, AO; Dvorák, M; Král, V; Králová, J; Lang, K; Lynch, V; Martásek, P; Sessler, JL | 1 |
| Beijnen, JH; Brandon, EF; Lazaro, LL; Manzanares, I; Meijerman, I; Schellens, JH; Sparidans, RW; van Ooijen, RD | 1 |
| Ackermann, C; Prusakiewicz, JJ; Voorman, R | 1 |
| Du, J; Huang, L; Jiang, F; Meng, X; Yu, X; Zeng, X; Zhao, Y | 1 |
| Chin, J; Livieri, M; Mancin, F; Saielli, G; Tonellato, U | 1 |
| Hashimoto, M; Imai, T; Masaki, K | 1 |
| Balani, SK; Callery, PS; Gan, LS; Li, P | 1 |
| Ghanem, E; Li, Y; Raushel, FM; Xu, C | 1 |
| Ackermann, C; Fate, G; Jewell, C; Payne, NA; Voorman, R; Williams, FM | 1 |
| Katada, H; Komiyama, M; Mizobe, Y; Seino, H; Sumaoka, J | 1 |
| Gerstl, C; Kaim, W; König, B; Sarkar, B; Subat, M; Woinaroschy, K | 1 |
| Beeby, A; Bushby, L; Fallis, IA; Griffiths, PC; Tatchell, T | 1 |
| Fujiyama, N; Habuchi, T; Inoue, K; Kagaya, H; Miura, M; Saito, M; Satoh, S; Suzuki, T | 1 |
| Manco, G; Mandrich, L | 1 |
| Chen, L; Chen, YX; Davey, AK; Liu, XQ; Wang, JP; Yang, J | 1 |
| Ercan, A; Grossman, SH; Ming, LJ; Tay, WM | 1 |
| Imai, T; Ninomiya, S; Ohura, K; Sakamoto, H | 1 |
| Chanoine, JP; Ni, H; Walia, P | 1 |
| Absillis, G; Parac-Vogt, TN; Ramadan, AM; Steens, N | 1 |
| Claffey, J; Erxleben, A; Tacke, M | 1 |
| Lam, TC; Leung, WH; Williams, ID; Yi, XY | 1 |
| Brugger, J; Graham, B; Joshi, T; Spiccia, L; Tjioe, L | 1 |
| Cai, BW; Chen, J; Jiang, HF; Liu, B; Lu, JX; Ren, YW; Shi, DB; Zheng, D | 1 |
| Bao, N; Borjihan, G; Hu, M; Jia, J; Li, S; Lu, Y; Ma, Y; Wang, Y; Yang, D; Yu, C | 1 |
| Graham, B; Joshi, T; Meininger, A; Spiccia, L; Tjioe, L | 1 |
| Chan, CP; Chang, MC; Chuang, FH; Jeng, JH; Jeng, PY; Lee, JJ; Lin, HJ; Lin, LD; Tseng, WY; Wang, TM | 1 |
| Carr, PD; Foo, JL; Gahan, LR; Ollis, DL; Schenk, G; Yip, SH | 1 |
| Cheng, KW; Constantinides, PP; Rigas, B; Wong, CC; Xie, G; Zhou, D; Zhu, CH | 1 |
| Aschenbrenner, J; Gruber, B; Kataev, E; König, B; Stadlbauer, S | 1 |
| Brugger, J; Forsyth, CM; Graham, B; Joshi, T; Moubaraki, B; Murray, KS; Spiccia, L; Tjioe, L | 1 |
| Ji, LN; Jiang, XQ; Mao, ZW; Zhao, C; Zhao, M | 1 |
| Absillis, G; Parac-Vogt, TN; Vanhaecht, S | 1 |
| Beijnen, JH; Damen, CW; Iusuf, D; Lagas, JS; Schinkel, AH; van Waterschoot, RA | 1 |
| Chang, Q; Han, R; Hu, X; Liao, YH; Liu, CY; Quan, LH; Wei, XL | 1 |
| Angiolillo, DJ; Brinda, BJ; Gawronski, BE; Markowitz, JS; Wang, X; Zhu, HJ | 1 |
| Nonin-Lecomte, S; Réty, S; Robert-Paganin, J | 1 |
| Chan, CP; Chang, HH; Chang, MC; Huang, GF; Jeng, JH; Lee, YL; Tseng, SK; Wang, HH; Wang, YL; Yeung, SY | 1 |
| Daumann, LJ; Gahan, LR; Larrabee, JA; Ollis, D; Schenk, G | 1 |
| Herschlag, D; Sunden, F; Wiersma-Koch, H | 1 |
| Lis, T; Starynowicz, P | 1 |
| Phillips, DL; Zhang, X; Zhao, C; Zheng, X | 1 |
| Baggerman, G; Beutels, F; Brusten, W; Landuyt, B; Maes, E; Mertens, I; Schoofs, L; Tirez, K; Valkenborg, D | 1 |
| Chamnanya, S; Lumjuan, N; Somboon, P; Yanola, J | 1 |
| Liu, X; Phillips, DL; Zhang, X; Zhao, C | 1 |
| Chen, LQ; Cheng, Y; Gong, DY; Shen, JL; Tao, J; Yun, RR; Zhou, YH | 1 |
| Chigwechokha, PK; Furukawa, T; Hashimoto, M; Hotta, Y; Ikema, S; Komatsu, M; Shimono, T; Shiozaki, K; Sugiyama, Y; Takumi, S | 1 |
| Fujita, KI; Fukuchi, K; Hokama, T; Kawai, K; Kobayashi, M; Mizutani, A; Nishi, K; Nishii, R; Shikano, N; Takahashi, K; Takasu, H | 1 |
| Hollis, T; Mauney, CH; Perrino, FW | 1 |
| Dong, P; Gao, J; Li, X; Liu, X; Wang, Q; Wu, Z | 1 |
| Ejaz, A; Ghosh, S; Repeta, L; Shuman, S | 1 |
| Buettner, KM; Paredes, A; Peduzzi, OM; Reig, AJ | 1 |
| Arman, H; Foley, W; Musie, GT | 1 |
1 trial(s) available for bis(4-nitrophenyl)phosphate and nitrophenols
| Article | Year |
|---|---|
Carboxylesterase expression in human dental pulp cells: role in regulation of BisGMA-induced prostanoid production and cytotoxicity.
Topics: Adolescent; Adult; Animals; Antidiarrheals; Bisphenol A-Glycidyl Methacrylate; Carboxylesterase; Cells, Cultured; Child; Cytotoxins; Dental Pulp; Dentin-Bonding Agents; Dinoprost; Dinoprostone; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Humans; Inflammation; Isoenzymes; Loperamide; Male; Materials Testing; Nitrophenols; Reactive Oxygen Species; Swine | 2012 |
126 other study(ies) available for bis(4-nitrophenyl)phosphate and nitrophenols
| Article | Year |
|---|---|
A method for the estimation of esterase synthesis and degradation and its application to evaluate the influence of insulin and glucagon.
Topics: Animals; Diabetes Mellitus, Experimental; Esterases; Glucagon; Insulin; Kinetics; Liver; Male; Mathematics; Microsomes, Liver; Nitrophenols; Organophosphorus Compounds; Protein Binding; Rats | 1979 |
Genetically defined lysosomal acetylesterase EC 3.1.1.6 in the cauda epididymidis of mouse, rat, and man.
Topics: 4-Chloromercuribenzenesulfonate; Acetylesterase; Animals; Electrophoresis, Polyacrylamide Gel; Epididymis; Histocytochemistry; Humans; Immunohistochemistry; Isoelectric Focusing; Isoflurophate; Lysosomes; Male; Mice; Mice, Inbred Strains; Nitrophenols; Physostigmine; Rats; Rats, Inbred Strains | 1992 |
Inhibition of protein synthesis increases the transcription of the phenobarbital-inducible CYP2H1 and CYP2H2 genes in chick embryo hepatocytes.
Topics: Animals; Base Sequence; Chick Embryo; Cycloheximide; Gene Expression; Liver; Molecular Sequence Data; Nitrophenols; Oligodeoxyribonucleotides; Phenobarbital; Protein Synthesis Inhibitors; RNA, Messenger; Structure-Activity Relationship; Transcription, Genetic | 1992 |
Cytotoxicity of dibasic esters (DBE) metabolites in rat nasal explants.
Topics: Acid Phosphatase; Animals; Carboxylic Ester Hydrolases; Cell Survival; Dicarboxylic Acids; Dose-Response Relationship, Drug; Epithelium; Female; Methylation; Nitrophenols; Nose; Organ Culture Techniques; Rats; Rats, Inbred Strains; Turbinates | 1991 |
Evidence against deacetylation and for cytochrome P450-mediated activation in acetaminophen-induced nephrotoxicity in the CD-1 mouse.
Topics: Acetaminophen; Acetylation; Aminophenols; Animals; Blood Urea Nitrogen; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Kidney Diseases; Kidney Tubular Necrosis, Acute; Kidney Tubules, Proximal; Male; Mice; Nitrophenols; Piperonyl Butoxide; Proteins; Tritolyl Phosphates | 1991 |
Carboxylesterase-dependent cytotoxicity of dibasic esters (DBE) in rat nasal explants.
Topics: Acid Phosphatase; Adipates; Administration, Inhalation; Animals; Carboxylic Ester Hydrolases; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Glutarates; Hydrolysis; Nasal Cavity; Nasal Mucosa; Nitrophenols; Olfactory Mucosa; Rats; Succinates; Time Factors | 1991 |
A comparison of the inhibition of deacetylase in primary cultures of rat and human hepatocytes effecting metabolism and DNA-binding of 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Adult; Aged; Amidohydrolases; Animals; Cell Survival; Cells, Cultured; DNA; Female; Humans; Liver; Male; Nitrophenols; Paraoxon; Rats; Species Specificity | 1990 |
First-pass metabolism of inspired ethyl acetate in the upper respiratory tracts of the F344 rat and Syrian hamster.
Topics: Acetates; Acetone; Animals; Carboxylic Ester Hydrolases; Cricetinae; Hydrolysis; Kinetics; Male; Mesocricetus; Nasal Cavity; Nitrophenols; Rats; Rats, Inbred F344; Tritolyl Phosphates | 1990 |
Bioactivation of N-arylhydroxamic acids by rat hepatic N-acetyltransferase. Detection of multiple enzyme forms by mechanism-based inactivation.
Topics: Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Biotransformation; Enzyme Activation; Hydroxamic Acids; Hydroxyacetylaminofluorene; Isoenzymes; Liver; Nitrophenols; Paraoxon; Protein Binding; Rats; Substrate Specificity | 1990 |
Aspirin hydrolyzing esterases from rat liver cytosol.
Topics: Animals; Aspirin; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cytosol; Esterases; Hydrogen-Ion Concentration; Hydrolysis; Isoenzymes; Liver; Molecular Weight; Nitrophenols; Paraoxon; Rats; Substrate Specificity | 1990 |
Characterization of phosphohydrolase activity in bovine spleen extracts: identification of a bis(p-nitrophenyl)phosphate-hydrolyzing activity (phosphodiesterase IV) which also acts on adenosine triphosphate.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Triphosphatases; Animals; Cattle; Cyclic Nucleotide Phosphodiesterases, Type 4; Hydrolysis; Nitrophenols; Phosphoric Diester Hydrolases; Spleen; Substrate Specificity | 1985 |
The metabolism of N-acetyl-3,5-dimethyl-p-benzoquinone imine in isolated hepatocytes involves N-deacetylation.
Topics: Acetylation; Animals; Benzoquinones; Cell Survival; Dithioerythritol; Glutathione; Imines; In Vitro Techniques; Liver; Male; Nitrophenols; Oxidation-Reduction; Quinones; Rats; Rats, Inbred Strains | 1988 |
Lymph esterases of the house mouse (Mus musculus)--I. Identification and possible origins of abdominal lymph esterases.
Topics: Abdomen; Animals; Carboxylesterase; Carboxylic Ester Hydrolases; Electrophoresis, Polyacrylamide Gel; Isoenzymes; Jejunum; Kidney; Liver; Lymph; Male; Mice; Mice, Inbred Strains; Nitrophenols | 1988 |
Lymph esterases of the house mouse (Mus musculus)--II. The role of esterase-2 in fat resorption.
Topics: Animals; Carboxylesterase; Carboxylic Ester Hydrolases; Chylomicrons; Fat Emulsions, Intravenous; Isoenzymes; Lipid Metabolism; Lymph; Male; Mice; Mice, Inbred Strains; Nitrophenols; Triglycerides | 1988 |
Genetic variation as a tool for histochemical localization of a nonspecific esterase.
Topics: Animals; Carboxylesterase; Carboxylic Ester Hydrolases; Female; Genetic Variation; Histocytochemistry; Isoenzymes; Male; Mice; Mice, Inbred Strains; Nitrophenols | 1988 |
The essential role of microsomal deacetylase activity in the metabolic activation, DNA-(deoxyguanosin-8-yl)-2-aminofluorene adduct formation and initiation of liver tumors by N-hydroxy-2-acetylaminofluorene in the livers of infant male B6C3F1 mice.
Topics: 2-Acetylaminofluorene; Amidohydrolases; Animals; Animals, Newborn; Biotransformation; Cytosol; DNA Damage; Hydroxyacetylaminofluorene; Liver Neoplasms; Male; Mice; Microsomes, Liver; Nitrophenols; Rats | 1988 |
Effect of the carboxylesterase inhibitor bis-(4-nitrophenyl)phosphate in vivo on aspirin hydrolase and carboxylesterase activities at first-pass sites of metabolism in the guinea pig.
Topics: Administration, Oral; Animals; Carboxylic Ester Hydrolases; Gastric Mucosa; Guinea Pigs; Kinetics; Liver; Male; Nitrophenols | 1987 |
Influence of the carboxylesterase inhibitor bis-p-nitrophenylphosphate on the rates of hydrolysis of various alpha-esters of 1-(N-methyl-N-nitrosamino)-methanol in vitro and in vivo and on the acute toxicity and carcinogenicity of 1-(N-methyl-N-nitrosamin
Topics: Animals; Carboxylic Ester Hydrolases; Carcinogens; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drug Interactions; Half-Life; Hydrolysis; Lethal Dose 50; Male; Neoplasms, Experimental; Nitrophenols; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Suicidal destruction of cytochrome P-450 and reduction of ferrochelatase activity by 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine and its analogues in chick embryo liver cells.
Topics: Animals; Cells, Cultured; Chick Embryo; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Ferrochelatase; Heme; Liver; Lyases; Nitrophenols; Porphyrins; Pyridines | 1985 |
Comparison of central nervous system actions of taurine and N-pivaloyltaurine.
Topics: Animals; Blood-Brain Barrier; Body Temperature; Brain; Brain Chemistry; Dopamine; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Mice; Mice, Inbred Strains; Motor Activity; Nitrophenols; Pentobarbital; Sleep; Taurine | 1985 |
The role of p-aminophenol in acetaminophen-induced nephrotoxicity: effect of bis(p-nitrophenyl) phosphate on acetaminophen and p-aminophenol nephrotoxicity and metabolism in Fischer 344 rats.
Topics: Acetaminophen; Aminophenols; Animals; Body Weight; Injections, Intraperitoneal; Kidney Cortex Necrosis; Male; Nitrophenols; Organ Size; Rats; Rats, Inbred F344 | 1985 |
The relevance of alpha-naphthyl acetate esterases to various monocyte functions.
Topics: Cell Adhesion; Cytotoxicity, Immunologic; Humans; Isoelectric Focusing; Monocytes; Naphthol AS D Esterase; Nitrophenols; Phagocytosis | 1985 |
Acid phosphatases from Fusarium moniliforme. 3. Mode of action of acid phosphatase II on bis-p-nitrophenyl phosphate.
Topics: Acid Phosphatase; Chemical Phenomena; Chemistry; Fusarium; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Nitrophenols; Organophosphorus Compounds; Phosphates | 1973 |
A comparative kinetic analysis of six substrates widely used for the detection and quantitation of phosphodiesterase I.
Topics: Animals; Cattle; Hydrolysis; Hymecromone; Kinetics; Nitrophenols; Phosphodiesterase I; Phosphoric Diester Hydrolases; Substrate Specificity | 1984 |
Comparative chemical and immunological characterization of five lipolytic enzymes (carboxylesterases) from rat liver microsomes.
Topics: Amino Acids; Animals; Binding Sites; Carbohydrates; Carboxylic Ester Hydrolases; Chymotrypsin; Epitopes; Immunodiffusion; Isoelectric Point; Lipolysis; Microsomes, Liver; Monoacylglycerol Lipases; Nitrophenols; Peptide Fragments; Rats; Trypsin | 1984 |
Inhibition of glycosyltransferases by bis-(p-nitrophenyl)phosphate: general effect and relation to their membrane integration.
Topics: Animals; Fucosyltransferases; Glucosyltransferases; Hexosyltransferases; Kinetics; Lymphocytes; Mannosyltransferases; Nitrophenols; Rats; Rats, Inbred Strains; Sialyltransferases; Spleen; Transferases | 1983 |
A lysosomal enzyme involved in diphosphatidylglycerol degradation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cardiolipins; Cyclic Nucleotide Phosphodiesterases, Type 4; Liver; Lysosomes; Nitrophenols; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats; Substrate Specificity | 1981 |
The effects of phenobarbital, bis-p-nitrophenyl phosphate and disulfiram on the hydrolysis of propanidid in Wistar rats.
Topics: Animals; Carboxylic Ester Hydrolases; Chromatography, High Pressure Liquid; Cytosol; Disulfiram; Dogs; Hydrolysis; Liver; Male; Microsomes, Liver; Nitrophenols; Phenobarbital; Propanidid; Rats; Rats, Inbred Strains; Sleep; Time Factors | 1984 |
Characterization of aspirin hydrolase of guinea-pig liver cytoplasm.
Topics: Animals; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Nucleus; Cytoplasm; Guinea Pigs; Liver; Microsomes, Liver; Mitochondria, Liver; Molecular Weight; Nitrophenols | 1984 |
Partial purification and characterization of a microsomal carboxylesterase specific for salicylate esters from guinea-pig liver.
Topics: Animals; Aspirin; Carboxylesterase; Carboxylic Ester Hydrolases; Esters; Female; Guinea Pigs; Kinetics; Male; Microsomes, Liver; Molecular Weight; Nitrophenols; Salicylates; Substrate Specificity | 1984 |
Differentiation of microsomal and cytosolic carboxylesterases in the rat liver by in vivo and in vitro inhibition.
Topics: Animals; Carboxylic Ester Hydrolases; Cytosol; Disulfiram; In Vitro Techniques; Isoflurophate; Liver; Male; Microsomes, Liver; Nitrophenols; Rats; Rats, Inbred Strains | 1984 |
Two-dimensional separation of alpha-naphthyl acetate esterases in human leucocytes and platelets.
Topics: Blood Platelets; Carboxylic Ester Hydrolases; Electrophoresis, Polyacrylamide Gel; Humans; Isoelectric Focusing; Isoflurophate; Leukocytes; Molecular Weight; Naphthol AS D Esterase; Nitrophenols; Sodium Fluoride | 1984 |
Isoniazid hepatoxicity: the relationship between covalent binding and metabolism in vivo.
Topics: Acetylation; Amidohydrolases; Animals; Biotransformation; Carbon Dioxide; Chemical and Drug Induced Liver Injury; Cobalt; Hydrolysis; Isoniazid; Liver; Male; Microsomes, Liver; Nitrophenols; Organophosphorus Compounds; Phenobarbital; Protein Binding; Rats | 1980 |
A rat liver microsomal carboxyesterase and a bilirubin UDP-glucuronyl transferase are responsible for the formation of bilirubin glucuronides from bilirubin dimethyl ester.
Topics: Animals; Bilirubin; Carboxylic Ester Hydrolases; Chromatography, DEAE-Cellulose; Glucuronosyltransferase; Microsomes, Liver; Nitrophenols; Rats; Rats, Inbred Strains | 1981 |
Esterase-17 (ES-17): characterization and genetic location on chromosome 9 of a bis-p-nitrophenyl phosphate-resistant esterase of the house mouse (Mus musculus).
Topics: Acetylesterase; Animals; Carboxylic Ester Hydrolases; Chromosomes; Genes; Genes, Dominant; Genetic Variation; Mice; Mice, Inbred Strains; Nitrophenols; Phenotype; Species Specificity; Tissue Distribution | 1983 |
Preferential localization of a protein methylating-demethylating system in proximal tubules of rat kidney.
Topics: Animals; Carboxylesterase; Carboxylic Ester Hydrolases; Kidney Cortex; Kidney Tubules, Proximal; Male; Methylation; Molecular Weight; Nephrons; Nitrophenols; Protein Methyltransferases; Protein O-Methyltransferase; Rats; Subcellular Fractions; Substrate Specificity; Tissue Distribution | 1982 |
Effect of bis-(p-nitrophenyl) phosphate on the biosynthesis and the utilization of lipid-intermediates.
Topics: Animals; Glucose; Lipid Metabolism; Lipids; Lymphocytes; Mannose; Nitrophenols; Polyisoprenyl Phosphate Monosaccharides; Polyisoprenyl Phosphate Oligosaccharides; Rats; Rats, Inbred Strains | 1982 |
Cross-linking experiments for the elucidation of the quarternary structure of carboxylesterase in the microsomal membrane.
Topics: Animals; Carbon Radioisotopes; Carboxylic Ester Hydrolases; Cross-Linking Reagents; Intracellular Membranes; Macromolecular Substances; Male; Microsomes, Liver; Molecular Weight; Nitrophenols; Organophosphorus Compounds; Rats | 1980 |
Kinetic characterization of enzyme forms involved in metal ion activation and inhibition of myo-inositol monophosphatase.
Topics: Animals; Base Sequence; Cattle; DNA Primers; Enzyme Activation; Kinetics; Metals; Molecular Sequence Data; Nitrophenols; Phosphoric Monoester Hydrolases; Substrate Specificity | 1995 |
Contribution of oxidation and deacetylation to the bioactivation of acetaminophen in vitro in liver and kidney from male and female Sprague-Dawley rats.
Topics: Acetaminophen; Animals; Biotransformation; Carbon Radioisotopes; Female; Kidney; Kidney Diseases; Liver; Male; Nitrophenols; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sex Factors; Triazoles | 1995 |
Biotransformation of carcinogenic arylamines and arylamides by human placenta.
Topics: 2-Acetylaminofluorene; Acetylation; Biotransformation; Carcinogens; Female; Fluorenes; Humans; Isocyanates; Microsomes, Liver; Nitrophenols; Placenta; Pregnancy | 1994 |
Human liver arylacetamide deacetylase. Molecular cloning of a novel esterase involved in the metabolic activation of arylamine carcinogens with high sequence similarity to hormone-sensitive lipase.
Topics: 2-Acetylaminofluorene; 2-Naphthylamine; Amidohydrolases; Amino Acid Sequence; Base Sequence; Carboxylic Ester Hydrolases; Carcinogens; Cloning, Molecular; DNA, Complementary; Humans; Liver; Microsomes, Liver; Molecular Sequence Data; Nitrophenols; Peptide Fragments; Phenylmethylsulfonyl Fluoride; Sequence Analysis; Sequence Homology, Amino Acid; Tissue Distribution | 1994 |
The function of esterases in insecticide resistance in Culex quinquefasciatus mosquitoes from Sri Lanka.
Topics: Animals; Carboxylic Ester Hydrolases; Chromatography; Chromatography, Ion Exchange; Culex; Durapatite; Edetic Acid; Insecticide Resistance; Insecticides; Kinetics; Molecular Weight; Nitrophenols; Paraoxon; Physostigmine; Serine Endopeptidases; Sri Lanka | 1993 |
Cytotoxicity and DNA-protein crosslink formation in rat nasal tissues exposed to vinyl acetate are carboxylesterase-mediated.
Topics: Acetaldehyde; Animals; Carboxylic Ester Hydrolases; Cell Survival; DNA; Dose-Response Relationship, Drug; Male; Nasal Mucosa; Nitrophenols; Nose; Proteins; Rats; Semicarbazides; Turbinates; Vinyl Compounds | 1993 |
Organophosphate sensitive and insensitive carboxylesterases in human skin.
Topics: Carboxylic Ester Hydrolases; Chromatography; Female; Humans; Isoelectric Focusing; Kinetics; Male; Nitrophenols; Paraoxon; Sensitivity and Specificity; Skin | 1993 |
Bioactivation of bis[p-nitrophenyl]phosphate by phosphoesterases of the earthworm, Lumbricus terrestris.
Topics: Animals; Biotransformation; Carboxylic Ester Hydrolases; Nitrophenols; Oligochaeta; Organophosphorus Compounds; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases | 1993 |
Differentiation of esterases reacting with organophosphorus compounds.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aryldialkylphosphatase; Cholinesterase Inhibitors; Cholinesterases; Edetic Acid; Esterases; Female; Humans; Hydrolysis; Kinetics; Male; Middle Aged; Naphthaleneacetic Acids; Nitrophenols; Organophosphates; Organophosphorus Compounds; Paraoxon; Phenylacetates; Phosphoric Monoester Hydrolases; Physostigmine; Sensitivity and Specificity; Substrate Specificity; Tetraisopropylpyrophosphamide; Thiocholine | 1993 |
Acyl-coenzyme A:cholesterol O-acyltransferase is not identical to liver microsomal carboxylesterase.
Topics: Acetyl-CoA Hydrolase; Animals; Carboxylesterase; Carboxylic Ester Hydrolases; Esterases; Hydroxymercuribenzoates; In Vitro Techniques; Isoflurophate; Male; Microsomes, Liver; Nitrophenols; Rats; Rats, Sprague-Dawley; Sterol O-Acyltransferase | 1996 |
Physiologically based modeling of vinyl acetate uptake, metabolism, and intracellular pH changes in the rat nasal cavity.
Topics: Acetaldehyde; Acetic Acid; Animals; Computer Simulation; Enzyme Inhibitors; Hydrogen-Ion Concentration; Male; Models, Biological; Mucous Membrane; Nasal Cavity; Nitrophenols; Rats; Solubility; Vinyl Compounds | 1997 |
Modulating role of endogenous reduced glutathione in tert-butyl hydroperoxide-induced cell injury in isolated rat hepatocytes.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cells, Cultured; Dipeptides; Glutathione; Lipid Peroxides; Liver; Male; Nitrophenols; Peroxides; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfhydryl Compounds; tert-Butylhydroperoxide | 1997 |
In vitro transesterification of cocaethylene (ethylcocaine) in the presence of ethanol. esterase-mediated ethyl ester exchange esterase-mediated ethyl ester exchange.
Topics: Animals; Cocaine; Enzyme Inhibitors; Esterases; Ethanol; Kinetics; Liver; Male; Nitrophenols; Physostigmine; Rats; Rats, Sprague-Dawley; Tritium | 1998 |
Inhibition of isoniazid-induced hepatotoxicity in rabbits by pretreatment with an amidase inhibitor.
Topics: Amidohydrolases; Animals; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1 Inhibitors; Enzyme Inhibitors; Glutathione; Hydrazines; In Vitro Techniques; Isoniazid; Male; Microsomes, Liver; Nitrophenols; Rabbits; Triglycerides | 1999 |
High-affinity nasal extraction of vinyl acetate vapor is carboxylesterase dependent.
Topics: Algorithms; Animals; Carboxylic Ester Hydrolases; Cytochrome P-450 CYP2E1; Enzyme Inhibitors; In Vitro Techniques; Inhalation Exposure; Models, Biological; Nasal Lavage Fluid; Nasal Mucosa; Nitrophenols; Rats; Rats, Inbred Strains; Vinyl Compounds | 1999 |
Stability of cytotoxic luteinizing hormone-releasing hormone conjugate (AN-152) containing doxorubicin 14-O-hemiglutarate in mouse and human serum in vitro: implications for the design of preclinical studies.
Topics: Adult; Animals; Antineoplastic Agents; Bombesin; Carboxylesterase; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation, Preclinical; Drug Interactions; Drug Stability; Gonadotropin-Releasing Hormone; Half-Life; Humans; Hydrolysis; Isoflurophate; Male; Mice; Mice, Nude; Nitrophenols; Paraoxon; Pyrroles; Weight Loss | 2000 |
Novel subtype of type IIs restriction enzymes. BfiI endonuclease exhibits similarities to the EDTA-resistant nuclease Nuc of Salmonella typhimurium.
Topics: Amino Acid Sequence; Bacterial Proteins; Catalytic Domain; Cloning, Molecular; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Methylation; DNA Restriction Enzymes; DNA-Cytosine Methylases; DNA, Complementary; Dose-Response Relationship, Drug; Edetic Acid; Endonucleases; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Magnesium; Micrococcal Nuclease; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrophenols; Oligonucleotides; Plasmids; Protein Folding; Protein Structure, Tertiary; Salmonella typhimurium; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sulfites; Time Factors | 2000 |
Affinity and nuclease activity of macrocyclic polyamines and their CuII complexes.
Topics: Binding Sites; Copper; Crystallography, X-Ray; DNA; Hydrolysis; Ligands; Molecular Conformation; Nitrophenols; Polyamines; Potentiometry; Ribonucleases; RNA; Solutions; Temperature | 2000 |
Methyl methacrylate toxicity in rat nasal epithelium: studies of the mechanism of action and comparisons between species.
Topics: Animals; Carboxylesterase; Carboxylic Ester Hydrolases; Chromatography, High Pressure Liquid; Cricetinae; Enzyme Inhibitors; Female; Histocytochemistry; Humans; Liver; Male; Mesocricetus; Methacrylates; Methylmethacrylate; Nasal Mucosa; Nitrophenols; Rats; Rats, Inbred F344; Species Specificity | 2001 |
Functional interrelationships in the alkaline phosphatase superfamily: phosphodiesterase activity of Escherichia coli alkaline phosphatase.
Topics: Alkaline Phosphatase; Amino Acid Substitution; Aniline Compounds; Arginine; Binding Sites; Enzyme Activation; Escherichia coli; Hot Temperature; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Nitrophenols; Organophosphorus Compounds; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Serine; Substrate Specificity | 2001 |
Concentration-dependent effects of the esterase inhibitor BNPP on macrophage migration and myelin phagocytosis.
Topics: Animals; Cell Count; Cell Movement; Cell Survival; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Enzyme Inhibitors; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Microscopy, Electron; Myelin Sheath; Naphthol AS D Esterase; Nitrophenols; Peripheral Nerves; Phagocytosis; Sciatic Nerve; Trypan Blue; Wallerian Degeneration | 2001 |
Concerning two-metal cooperativity in model phosphate hydrolysis.
Topics: Catalysis; Dinucleoside Phosphates; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Kinetics; Ligands; Nitrophenols; Organometallic Compounds; Organophosphates; Organophosphorus Compounds | 2001 |
Triisopropyltriazacyclononane copper(II): an efficient phosphodiester hydrolysis catalyst and DNA cleavage agent.
Topics: Catalysis; Copper; DNA; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Molecular Structure; Nitrophenols; Organometallic Compounds; Plasmids; Temperature | 2002 |
Vinyl acetate-induced intracellular acidification: implications for risk assessment.
Topics: Animals; Carboxylesterase; Carboxylic Ester Hydrolases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hepatocytes; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Models, Biological; Nitrophenols; Rats; Rats, Inbred Strains; Risk Assessment; Time Factors; Vinyl Compounds | 2002 |
Sensory nerve-mediated nasal vasodilatory response to inspired ethyl acrylate.
Topics: Acetone; Acrylates; Administration, Inhalation; Airway Resistance; Animals; Capsaicin; Carboxylesterase; Carboxylic Ester Hydrolases; Enzyme Inhibitors; Irritants; Male; Nasal Cavity; Neurons, Afferent; Nitrophenols; Rats; Rats, Inbred F344; Vasodilation | 2002 |
Gene Cloning, purification, and characterization of a phosphodiesterase from Delftia acidovorans.
Topics: Bacterial Proteins; Betaproteobacteria; Cloning, Molecular; Cyclic AMP; Kinetics; Molecular Sequence Data; Nitrophenols; Phosphoric Diester Hydrolases; Recombinant Proteins; Sequence Analysis, DNA | 2003 |
Vinyl acetate decreases intracellular pH in rat nasal epithelial cells.
Topics: Animals; Benzopyrans; Carboxylesterase; Cells, Cultured; Dose-Response Relationship, Drug; Drug Antagonism; Enzyme Inhibitors; Hydrogen-Ion Concentration; Male; Microscopy, Confocal; Naphthols; Nitrophenols; Olfactory Mucosa; Rats; Rats, Inbred Strains; Rhodamines; Vinyl Compounds | 2003 |
Evidence for the involvement of a pulmonary first-pass effect via carboxylesterase in the disposition of a propranolol ester derivative after intravenous administration.
Topics: Adrenergic beta-Antagonists; Algorithms; Animals; Antibodies, Blocking; Area Under Curve; Carboxylic Ester Hydrolases; Chromatography, High Pressure Liquid; Cytosol; Dogs; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Hydrolysis; Injections, Intra-Arterial; Injections, Intravenous; Isoenzymes; Lung; Male; Microsomes; Nitrophenols; Propranolol; Rats; Rats, Wistar; Species Specificity; Stereoisomerism | 2003 |
Geometry-dependent phosphodiester hydrolysis catalyzed by binuclear copper complexes.
Topics: Catalysis; Copper; Crystallography, X-Ray; DNA; Electrophoresis, Agar Gel; Hydrolysis; Kinetics; Ligands; Models, Molecular; Molecular Structure; Nitrophenols; Organophosphates; Phosphoric Diester Hydrolases; Pyridines | 2003 |
Differential response of human ovarian cancer cells to induction of apoptosis by vitamin E Succinate and vitamin E analogue, alpha-TEA.
Topics: Apoptosis; Cell Division; Cell Line, Tumor; DNA, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Esterases; Female; Humans; Neoplastic Stem Cells; Nitrophenols; Ovarian Neoplasms; Tocopherols; Uterine Cervical Neoplasms; Vitamin E | 2004 |
In vitro and in vivo trans-esterification of 1-[2(R)-(2-amino-2-methylpropionylamino)-3-(1H-indol-3-yl)propionyl]-3(S)-benzyl-piperidine-3-carboxylic acid ethyl ester and the effects of ethanol on its pharmacokinetics in rats.
Topics: Administration, Oral; Animals; Area Under Curve; Carboxylic Acids; Carboxylic Ester Hydrolases; Chromatography, Liquid; Deuterium; Drug Evaluation, Preclinical; Drug Interactions; Esterification; Esters; Ethanol; Human Growth Hormone; Hydrolysis; Injections, Intravenous; Male; Mass Spectrometry; Metabolic Clearance Rate; Microsomes, Liver; Nitrophenols; Piperidines; Rats; Rats, Sprague-Dawley | 2004 |
Identification of metal binding residues for the binuclear zinc phosphodiesterase reveals identical coordination as glyoxalase II.
Topics: Amino Acid Sequence; beta-Lactamases; Binding Sites; Catalysis; Escherichia coli; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrophenols; Phosphoric Diester Hydrolases; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Substrate Specificity; Thiolester Hydrolases; X-Rays; Zinc | 2004 |
New enzymatic assay using phospholipase D to measure total calcium in serum.
Topics: Calcium; Cations; Humans; Hydrolysis; Indicators and Reagents; Nitrophenols; Phospholipase D; Reproducibility of Results; Streptomyces | 2005 |
The phosphodiesterase activity of the HmsP EAL domain is required for negative regulation of biofilm formation in Yersinia pestis.
Topics: Bacterial Proteins; Biofilms; Coenzymes; Down-Regulation; Manganese; Nitrophenols; Phosphoric Diester Hydrolases; Protein Structure, Tertiary; Yersinia pestis | 2005 |
Identification of a novel keratinocyte retinyl ester hydrolase as a transacylase and lipase.
Topics: Acyltransferases; Carboxylic Ester Hydrolases; Catalysis; Cell Line, Tumor; DNA, Complementary; Drug Resistance; Enzyme Inhibitors; Esterification; Gene Library; Humans; Hydrogen-Ion Concentration; Hydrolysis; Keratinocytes; Lipase; Nitrophenols; Phenylmethylsulfonyl Fluoride; Proteins; Triolein | 2005 |
Stereospecific and regioselective hydrolysis of cannabinoid esters by ES46.5K, an esterase from mouse hepatic microsomes, and its differences from carboxylesterases of rabbit and porcine liver.
Topics: Animals; Cannabinoids; Carboxylic Ester Hydrolases; Catalysis; Hydrolysis; In Vitro Techniques; Male; Mice; Microsomes, Liver; Nitrophenols; Nonoxynol; Rabbits; Sodium Dodecyl Sulfate; Species Specificity; Stereoisomerism; Surface-Active Agents; Swine | 2005 |
Macrocyclic lanthanide complexes as artificial nucleases and ribonucleases: effects of pH, metal ionic radii, number of coordinated water molecules, charge, and concentrations of the metal complexes.
Topics: Deoxyribonucleases; Hydrogen-Ion Concentration; Ions; Lanthanoid Series Elements; Macrocyclic Compounds; Metals; Molecular Structure; Nitrophenols; Ribonucleases; Static Electricity; Water | 2005 |
Polyhydroxylated sapphyrins: multisite non-metallic catalysts for activated phosphodiester hydrolysis.
Topics: Catalysis; Hydrogen Bonding; Hydrolysis; Hydroxylation; Kinetics; Molecular Structure; Nitrophenols; Porphyrins; X-Ray Diffraction | 2006 |
In vitro characterization of the human biotransformation pathways of aplidine, a novel marine anti-cancer drug.
Topics: Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytosol; Depsipeptides; Female; Glucuronosyltransferase; Half-Life; Humans; Liver; Male; Metabolic Detoxication, Phase II; Microsomes, Liver; Mixed Function Oxygenases; Molecular Structure; Nitrophenols; Peptides, Cyclic; Phenylmethylsulfonyl Fluoride; Spectrophotometry, Ultraviolet; Subcellular Fractions | 2007 |
Comparison of skin esterase activities from different species.
Topics: Acetylcholinesterase; Animals; Blood; Carboxylesterase; Cholinesterase Inhibitors; Humans; In Vitro Techniques; Kinetics; Liver; Male; Naphthols; Neostigmine; Nitrophenols; Phenotype; Rats; Rats, Sprague-Dawley; Skin; Species Specificity; Swine; Swine, Miniature | 2006 |
Metallomicellar catalysis: hydrolysis of phosphate monoester and phosphodiester by Cu(II), Zn(II) complexes of pyridyl ligands in CTAB micellar solution.
Topics: Alkanes; Benzene Derivatives; Catalysis; Cetrimonium; Cetrimonium Compounds; Copper; Heptanes; Ligands; Micelles; Nitrophenols; Organophosphorus Compounds; Pyridines; Zinc | 2006 |
Mimicking enzymes: cooperation between organic functional groups and metal ions in the cleavage of phosphate diesters.
Topics: Catalysis; Esters; Kinetics; Methylamines; Nitrophenols; Organophosphates; Organophosphorus Compounds; Pyridines; Zinc | 2007 |
Intestinal first-pass metabolism via carboxylesterase in rat jejunum and ileum.
Topics: Aminopeptidases; Anilides; Aniline Compounds; Animals; Biotransformation; Carboxylic Ester Hydrolases; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hydrolysis; Ileum; Intestinal Absorption; Intestinal Mucosa; Isoenzymes; Jejunum; Male; Nitrophenols; Propranolol; Rats; Rats, Wistar; RNA, Messenger; Subcellular Fractions | 2007 |
Esterase inhibition attribute of grapefruit juice leading to a new drug interaction.
Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Beverages; Caco-2 Cells; Cell Membrane Permeability; Citrus paradisi; Enalapril; Enzyme Inhibitors; Esterases; Food-Drug Interactions; Fruit; Humans; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections, Intravenous; Intestinal Absorption; Intestines; Liver; Lovastatin; Male; Nitrophenols; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Swine | 2007 |
Characterization of a phosphodiesterase capable of hydrolyzing EA 2192, the most toxic degradation product of the nerve agent VX.
Topics: Chemical Warfare Agents; Cholinesterase Inhibitors; Disulfoton; Enterobacter aerogenes; Kinetics; Microbial Viability; Molecular Structure; Mutation; Nitrophenols; Organophosphates; Organophosphonates; Organothiophosphorus Compounds; Paraoxon; Phenols; Phosphoric Diester Hydrolases; Phosphoric Triester Hydrolases; Recombinant Proteins; Substrate Specificity | 2007 |
Specificity of procaine and ester hydrolysis by human, minipig, and rat skin and liver.
Topics: Animals; Enzyme Inhibitors; Esterases; Esters; Female; Humans; Hydrolysis; Liver; Loperamide; Male; Microsomes, Liver; Molecular Structure; Nitrophenols; Paraoxon; Pentanoic Acids; Phenylacetates; Phenylmethylsulfonyl Fluoride; Procaine; Rats; Rats, Wistar; Skin; Swine; Swine, Miniature; Umbelliferones | 2007 |
Crystal structure of Ce(IV)/dipicolinate complex as catalyst for DNA hydrolysis.
Topics: Base Sequence; Catalysis; Cerium; Crystallography, X-Ray; DNA; Hydrolysis; Kinetics; Ligands; Nitrophenols; Oligonucleotides; Picolinic Acids; Pyridines; Water | 2008 |
1,4,7,10-tetraazacyclododecane metal complexes as potent promoters of phosphodiester hydrolysis under physiological conditions.
Topics: Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Nitrophenols; Organometallic Compounds; Temperature; Water | 2008 |
Aqueous solutions of transition metal containing micelles.
Topics: Esters; Hydrolysis; Ions; Metals; Micelles; Molecular Structure; Nitrophenols; Phosphates; Picolinic Acids; Schiff Bases; Solutions; Surface-Active Agents; Transition Elements; Water | 2008 |
Influence of carboxylesterase 2 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients.
Topics: Adult; Alleles; Asian People; Carboxylesterase; Enzyme Inhibitors; Humans; Immunosuppressive Agents; Isoflurophate; Kidney Transplantation; Microsomes, Liver; Mycophenolic Acid; Nitrophenols; Phenylmethylsulfonyl Fluoride; Polymorphism, Genetic; Prednisolone; Tacrolimus | 2009 |
Evolution in the amidohydrolase superfamily: substrate-assisted gain of function in the E183K mutant of a phosphotriesterase-like metal-carboxylesterase.
Topics: Alphaproteobacteria; Amidohydrolases; Amino Acid Sequence; Binding Sites; Carboxylesterase; Escherichia coli; Evolution, Molecular; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Nitrophenols; Phosphoric Triester Hydrolases; Protein Conformation; Pseudomonas; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity | 2009 |
Effects of diammonium glycyrrhizinate on the pharmacokinetics of aconitine in rats and the potential mechanism.
Topics: Aconitine; Administration, Oral; Animals; Biological Transport; Cyclosporine; Disease Models, Animal; Enzyme Inhibitors; Glycyrrhizic Acid; Intestinal Absorption; Male; Membrane Transport Proteins; Nitrophenols; Rats; Rats, Sprague-Dawley; Time Factors; Verapamil | 2009 |
Mechanistic role of each metal ion in Streptomyces dinuclear aminopeptidase: PEPTIDE hydrolysis and 7x10(10)-fold rate enhancement of phosphodiester hydrolysis.
Topics: Aminopeptidases; Binding Sites; Coordination Complexes; Fluorides; Hydrolysis; Ions; Kinetics; Metals; Nitrophenols; Peptides; Streptomyces griseus | 2010 |
Development of a novel system for estimating human intestinal absorption using Caco-2 cells in the absence of esterase activity.
Topics: Biological Transport; Caco-2 Cells; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Membrane Permeability; Diffusion; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Esters; Humans; Intestinal Absorption; Nitrophenols; Prodrugs; Propranolol; Terfenadine | 2010 |
Ontogeny of acylated ghrelin degradation in the rat.
Topics: Acetylation; Aging; Animals; Animals, Newborn; Butyrylcholinesterase; Carboxylesterase; Cholinesterase Inhibitors; Female; Fetus; Ghrelin; Injections, Intraperitoneal; Male; Nitrophenols; Physostigmine; Pregnancy; Rats; Rats, Sprague-Dawley; Serine Proteinase Inhibitors; Serum; Sex Characteristics; Sulfones | 2010 |
Hydrolytic cleavage of DNA-model substrates promoted by polyoxovanadates.
Topics: DNA; Hydrogen-Ion Concentration; Hydrolysis; Magnetic Resonance Spectroscopy; Nitrophenols; Organophosphorus Compounds; Vanadium | 2010 |
Binding and hydrolysis studies of antitumoural titanocene dichloride and Titanocene Y with phosphate diesters.
Topics: Antineoplastic Agents; Clinical Trials as Topic; DNA; Enzyme Inhibitors; Esters; Humans; Hydrolysis; Molecular Structure; Nitrophenols; Organometallic Compounds; Phosphates; Solutions | 2010 |
Hydrolysis of bis(p-nitrophenyl)phosphate by tetravalent metal complexes with Klaui's oxygen tripodal ligand.
Topics: Cerium; Esters; Hafnium; Hydrolysis; Ligands; Nitrophenols; Organometallic Compounds; Oxygen | 2010 |
Synthesis, structure, and DNA cleavage properties of copper(II) complexes of 1,4,7-triazacyclononane ligands featuring pairs of guanidine pendants.
Topics: Anaerobiosis; Copper; Crystallography, X-Ray; DNA Cleavage; Esters; Free Radical Scavengers; Guanidine; Heterocyclic Compounds; Hydrogen Bonding; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Ligands; Nitrophenols; Phosphates; Plasmids; Reactive Oxygen Species; Solutions; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared | 2011 |
A novel asymmetric di-Ni(II) system as a highly efficient functional model for phosphodiesterase: synthesis, structures, physicochemical properties and catalytic kinetics.
Topics: Catalysis; Coordination Complexes; Crystallography, X-Ray; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Magnetics; Models, Molecular; Molecular Conformation; Nickel; Nitrophenols; Phosphoric Diester Hydrolases; Spectrophotometry, Ultraviolet | 2011 |
Contribution of carboxylesterase in hamster to the intestinal first-pass loss and low bioavailability of ethyl piperate, an effective lipid-lowering drug candidate.
Topics: Alkaloids; Animals; Anticholesteremic Agents; Benzodioxoles; Caco-2 Cells; Carboxylesterase; Cricetinae; Drug Stability; Fatty Acids, Unsaturated; Humans; Hydrolysis; Intestinal Absorption; Intestinal Mucosa; Male; Nitrophenols; Piperidines; Polyunsaturated Alkamides; RNA, Messenger | 2011 |
Efficient plasmid DNA cleavage by copper(II) complexes of 1,4,7-triazacyclononane ligands featuring xylyl-linked guanidinium groups.
Topics: Coordination Complexes; Copper; Crystallography, X-Ray; DNA; DNA Cleavage; DNA Restriction Enzymes; Electrophoresis, Agar Gel; Guanidine; Heterocyclic Compounds; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Ligands; Models, Molecular; Molecular Mimicry; Nitrophenols; Nucleic Acid Conformation; Plasmids; Protons; Water | 2011 |
Directed evolution combined with rational design increases activity of GpdQ toward a non-physiological substrate and alters the oligomeric structure of the enzyme.
Topics: Catalytic Domain; Chromatography, Gel; Directed Molecular Evolution; Enterobacter aerogenes; Hot Temperature; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Nitrophenols; Phosphoric Diester Hydrolases; Protein Multimerization; Substrate Specificity | 2011 |
Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Line, Tumor; Cell Survival; Drug Interactions; Drug Therapy, Combination; Enzyme Inhibitors; Female; HEK293 Cells; Humans; Hydrolysis; Ibuprofen; Indomethacin; Inhibitory Concentration 50; Kinetics; Mice; Mice, Inbred BALB C; Mice, Nude; Naproxen; Nitrophenols; Organophosphates; Organophosphorus Compounds; Phenylglyoxal; Stomach Neoplasms; Sulindac; Transfection; Valproic Acid; Xenograft Model Antitumor Assays | 2012 |
Vesicles and micelles from amphiphilic zinc(II)-cyclen complexes as highly potent promoters of hydrolytic DNA cleavage.
Topics: Cyclams; DNA; DNA Cleavage; Heterocyclic Compounds; Hydrolysis; Micelles; Nitrophenols; Zinc | 2011 |
Phosphodiester cleavage properties of copper(II) complexes of 1,4,7-triazacyclononane ligands bearing single alkyl guanidine pendants.
Topics: Copper; Crystallography, X-Ray; DNA Cleavage; Guanidine; Heterocyclic Compounds; Hydrogen Bonding; Ligands; Magnetic Phenomena; Molecular Structure; Nitrophenols; Organometallic Compounds; Organophosphates | 2012 |
Rapid hydrolysis of phosphate ester promoted by Ce(IV) conjugating with a β-cyclodextrin monomer and dimer.
Topics: beta-Cyclodextrins; Catalysis; Cerium; Dimerization; Esterases; Hydrolysis; Kinetics; Nitrophenols; Thermodynamics | 2012 |
Hydrolysis of DNA model substrates catalyzed by metal-substituted Wells-Dawson polyoxometalates.
Topics: Catalysis; DNA; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Metals; Nitrophenols; Organophosphorus Compounds; Tungsten Compounds | 2012 |
P-glycoprotein, multidrug-resistance associated protein 2, Cyp3a, and carboxylesterase affect the oral availability and metabolism of vinorelbine.
Topics: Administration, Oral; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; Biological Availability; Biological Transport; Carboxylesterase; Cytochrome P-450 CYP3A; Dogs; Female; Humans; In Vitro Techniques; Loperamide; Madin Darby Canine Kidney Cells; Mice; Mice, Knockout; Microsomes, Liver; Multidrug Resistance-Associated Protein 2; Nitrophenols; Up-Regulation; Vinblastine; Vinorelbine | 2012 |
Stabilization of zeylenone in rat plasma by the presence of esterase inhibitors and its LC-MS/MS assay for pharmacokinetic study.
Topics: Administration, Inhalation; Animals; Benzoates; Chromatography, High Pressure Liquid; Cyclohexanes; Dioxanes; Drug Stability; Enzyme Inhibitors; Esterases; Male; Nitrophenols; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Sodium Fluoride; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2013 |
Carboxylesterase 1 as a determinant of clopidogrel metabolism and activation.
Topics: Biotransformation; Carboxylic Ester Hydrolases; Cell Line; Clopidogrel; Humans; Hydrolysis; Liver; Nitrophenols; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine | 2013 |
Crystal structure of an EAL domain in complex with reaction product 5'-pGpG.
Topics: Amino Acid Sequence; Apoproteins; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Cyclic GMP; Deoxyguanine Nucleotides; Hydrolysis; Ligands; Magnesium; Models, Molecular; Molecular Sequence Data; Nitrophenols; Phosphoric Diester Hydrolases; Protein Binding; Protein Multimerization; Protein Structure, Tertiary; Pseudomonas aeruginosa; Sequence Alignment; Solutions | 2012 |
Urethane dimethacrylate induces cytotoxicity and regulates cyclooxygenase-2, hemeoxygenase and carboxylesterase expression in human dental pulp cells.
Topics: Acetylcysteine; Antioxidants; Carboxylesterase; Catalase; Cell Cycle; Cell Death; Cell Proliferation; Cell Shape; Cell Survival; Cyclooxygenase 2; Dental Pulp; Gene Expression Regulation; Heme Oxygenase (Decyclizing); Humans; Kinetics; Loperamide; Methacrylates; Nitrophenols; Polyurethanes; Protoporphyrins; RNA, Messenger | 2014 |
Immobilization of the enzyme GpdQ on magnetite nanoparticles for organophosphate pesticide bioremediation.
Topics: Biodegradation, Environmental; Dendrimers; Enterobacter aerogenes; Enzymes, Immobilized; Glutaral; Kinetics; Magnetite Nanoparticles; Mutation; Nitrophenols; Organophosphates; Pesticides; Phosphoric Diester Hydrolases; Photoelectron Spectroscopy; Serine; Water Purification | 2014 |
Site-directed mutagenesis maps interactions that enhance cognate and limit promiscuous catalysis by an alkaline phosphatase superfamily phosphodiesterase.
Topics: Adenosine Monophosphate; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Biocatalysis; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Methylation; Models, Molecular; Molecular Conformation; Mutant Proteins; Nitrophenols; Organophosphorus Compounds; Phosphoric Diester Hydrolases; Protein Interaction Maps; Pyrophosphatases; Recombinant Proteins; Substrate Specificity; Thymidine Monophosphate; Xanthomonas axonopodis; Zinc | 2013 |
Charge-density distribution in sodium bis(4-nitrophenyl)phosphate.
Topics: Crystallography, X-Ray; Models, Molecular; Molecular Conformation; Nitrophenols; Quantum Theory | 2014 |
Mechanistic investigation of the cleavage of phosphodiester catalyzed by a symmetrical oxyimine-based macrocyclic dinuclear zinc complex: a DFT study.
Topics: Catalysis; Coordination Complexes; Imines; Molecular Conformation; Nitrophenols; Thermodynamics; Zinc | 2014 |
The benefits and limitations of reaction cell and sector field inductively coupled plasma mass spectrometry in the detection and quantification of phosphopeptides.
Topics: Chromatography, High Pressure Liquid; Limit of Detection; Mass Spectrometry; Nitrophenols; Phosphopeptides; Signal-To-Noise Ratio | 2015 |
Insecticides resistance in the Culex quinquefasciatus populations from northern Thailand and possible resistance mechanisms.
Topics: Animals; Culex; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Insecticide Resistance; Insecticides; Larva; Malathion; Maleates; Mosquito Control; Nitriles; Nitrophenols; Permethrin; Piperonyl Butoxide; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyrethrins; Thailand; Voltage-Gated Sodium Channels | 2015 |
Hydrolysis mechanisms of BNPP mediated by facial copper(II) complexes bearing single alkyl guanidine pendants: cooperation between the metal centers and the guanidine pendants.
Topics: Aza Compounds; Catalysis; Copper; Guanidine; Hydrolysis; Molecular Conformation; Nitrophenols; Organometallic Compounds; Quantum Theory | 2016 |
Effective cleavage of phosphodiester promoted by the zinc(II) and copper(II) inclusion complexes of β-cyclodextrin.
Topics: beta-Cyclodextrins; Copper; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Nitrophenols; Zinc | 2016 |
Overexpression of carboxylesterase contributes to the attenuation of cyanotoxin microcystin-LR toxicity.
Topics: Absorption, Physiological; Bacterial Toxins; Binding Sites; Carboxylesterase; Carcinogens, Environmental; Cell Survival; Drug Resistance; Enzyme Induction; Enzyme Inhibitors; Green Fluorescent Proteins; HEK293 Cells; Hep G2 Cells; Humans; Inactivation, Metabolic; Marine Toxins; Microcystins; Nitrophenols; Organic Anion Transporters, Sodium-Independent; Recombinant Fusion Proteins; Recombinant Proteins; Solute Carrier Organic Anion Transporter Family Member 1B3; Substrate Specificity | 2017 |
123I-iomazenil whole-body imaging to detect hepatic carboxylesterase drug-metabolizing enzyme activity.
Topics: Animals; Carboxylesterase; Flumazenil; Liver; Male; Mice; Nitrophenols; Whole Body Imaging | 2018 |
Identification of Inhibitors of the dNTP Triphosphohydrolase SAMHD1 Using a Novel and Direct High-Throughput Assay.
Topics: Drug Discovery; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Manganese; Nitrophenols; Protein Multimerization; SAM Domain and HD Domain-Containing Protein 1 | 2018 |
Near-infrared emission tracks inter-individual variability of carboxylesterase-2 via a novel molecular substrate.
Topics: Benzoates; Carboxylesterase; Cell Line, Tumor; Density Functional Theory; Enzyme Inhibitors; Fluorescent Dyes; Humans; Infrared Rays; Microscopy, Confocal; Microscopy, Fluorescence; Models, Chemical; Nitriles; Nitrophenols | 2020 |
Pseudomonas putida MPE, a manganese-dependent endonuclease of the binuclear metallophosphoesterase superfamily, incises single-strand DNA in two orientations to yield a mixture of 3'-PO4 and 3'-OH termini.
Topics: Bacterial Proteins; Base Pairing; Catalytic Domain; Deoxyribonuclease I; DNA Mismatch Repair; DNA Repair; DNA Repair Enzymes; DNA, Single-Stranded; Histidine; Hydrolysis; Manganese; Models, Molecular; Nitrophenols; Phosphates; Protein Binding; Protein Conformation; Pseudomonas putida; Recombinant Proteins; Structure-Activity Relationship; Water | 2021 |
A de novo binuclear zinc enzyme with DNA cleavage activity.
Topics: DNA; DNA Cleavage; Endodeoxyribonucleases; Enzyme Assays; Kinetics; Nitrophenols; Plasmids; Zinc | 2021 |
Homodinuclear copper(II) and zinc(II) complexes of a carboxylate-rich ligand as synthetic mimics of phosphoester hydrolase in aqueous solutions.
Topics: Benzoates; Catalysis; Coordination Complexes; Copper; Hydrolysis; Kinetics; Ligands; Molecular Structure; Nitrophenols; Organophosphorus Compounds; Zinc | 2021 |