bis(1-piperidylthiocarbonyl)disulfide has been researched along with disulfiram in 5 studies
*Disulfiram: A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase. [MeSH]
*Disulfiram: A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Buckheit, RW; Clanton, D; Covell, DG; Graham, L; Rice, WG; Schaeffer, CA; Summers, MF; Turpin, JA; Wallqvist, A; Zaharevitz, D | 1 |
| Kapanda, CN; Labar, G; Lambert, DM; Muccioli, GG; Poupaert, JH | 1 |
| Brahemi, G; Brancale, A; Buac, D; Burger, AM; Fiasella, A; Kona, FR; Soukupová, J; Westwell, AD | 1 |
| Chen, X; Huang, YY; Li, J; Li, XK; Mao, F; Ni, SS; Ren, YL; Song, RR; Wan, J; Xu, YX; Zhang, C; Zhu, J | 1 |
| Omran, Z | 1 |
5 other study(ies) available for bis(1-piperidylthiocarbonyl)disulfide and disulfiram
| Article | Year |
|---|---|
Evaluation of selected chemotypes in coupled cellular and molecular target-based screens identifies novel HIV-1 zinc finger inhibitors.
Topics: Anti-HIV Agents; Binding Sites; Cells, Cultured; Disulfides; Guanidines; HIV-1; Humans; Hydrazines; Macrophages; Models, Molecular; Molecular Structure; Monocytes; RNA, Messenger; Virus Replication; Zinc Fingers | 1996 |
Bis(dialkylaminethiocarbonyl)disulfides as potent and selective monoglyceride lipase inhibitors.
Topics: Amidohydrolases; Disulfides; Enzyme Activation; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Monoacylglycerol Lipases; Mutation; Nitrogen; Oxidation-Reduction; Structure-Activity Relationship; Substrate Specificity | 2009 |
Exploring the structural requirements for inhibition of the ubiquitin E3 ligase breast cancer associated protein 2 (BCA2) as a treatment for breast cancer.
Topics: Aldehyde Dehydrogenase; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Disulfiram; Enzyme Inhibitors; Enzyme Stability; Gene Expression Regulation, Neoplastic; Humans; Structure-Activity Relationship; Substrate Specificity; Ubiquitin-Protein Ligases; Ubiquitination; Zinc | 2010 |
Development of disulfide-derived fructose-1,6-bisphosphatase (FBPase) covalent inhibitors for the treatment of type 2 diabetes.
Topics: Animals; Blood Glucose; Cysteine; Diabetes Mellitus, Type 2; Disulfides; Enzyme Inhibitors; Fructose-Bisphosphatase; Male; Mice; Structure-Activity Relationship | 2020 |
Development of new disulfiram analogues as ALDH1a1-selective inhibitors.
Topics: Acetaldehyde Dehydrogenase Inhibitors; Alcohol Deterrents; Aldehyde Dehydrogenase 1 Family; Aldehyde Dehydrogenase, Mitochondrial; Disulfiram; Enzyme Assays; Humans; Retinal Dehydrogenase; Substrate Specificity | 2021 |