Page last updated: 2024-09-04
birb 796 and trametinib
birb 796 has been researched along with trametinib in 2 studies
Compound Research Comparison
| Studies (birb 796) | Trials (birb 796) | Recent Studies (post-2010) (birb 796) | Studies (trametinib) | Trials (trametinib) | Recent Studies (post-2010) (trametinib) |
|---|---|---|---|---|---|
| 137 | 5 | 80 | 940 | 134 | 926 |
Protein Interaction Comparison
| Protein | Taxonomy | birb 796 (IC50) | trametinib (IC50) |
|---|---|---|---|
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | 0.0043 | |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | 0.0011 |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Juvale, K; Kharkar, PS; Sahu, NU; Shah, CP; Silbermann, K; Stefan, SM; Wiese, M | 1 |
Other Studies
2 other study(ies) available for birb 796 and trametinib
| Article | Year |
|---|---|
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Novel chalcone and flavone derivatives as selective and dual inhibitors of the transport proteins ABCB1 and ABCG2.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Chalcones; Drug Resistance, Multiple; Flavones; Humans; Structure-Activity Relationship | 2019 |