Page last updated: 2024-09-04

birb 796 and tanespimycin

birb 796 has been researched along with tanespimycin in 2 studies

Compound Research Comparison

Studies
(birb 796)
Trials
(birb 796)
Recent Studies (post-2010)
(birb 796)
Studies
(tanespimycin)
Trials
(tanespimycin)
Recent Studies (post-2010) (tanespimycin)
13758092139496

Protein Interaction Comparison

ProteinTaxonomybirb 796 (IC50)tanespimycin (IC50)
Corticotropin releasing hormone receptor 2Sus scrofa (pig)0.004
Lysine-specific demethylase 6BHomo sapiens (human)0.4
Lysine-specific demethylase 4BHomo sapiens (human)0.7
Tyrosine-protein kinase ABL1Homo sapiens (human)3
ATP-dependent molecular chaperone HSP82Saccharomyces cerevisiae S288C7.65
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)0.031
Heat shock protein HSP 90-alphaHomo sapiens (human)0.9391
Heat shock protein HSP 90-betaHomo sapiens (human)0.5124
Breakpoint cluster region proteinHomo sapiens (human)3
Lysine-specific demethylase 5AHomo sapiens (human)0.13
EndoplasminCanis lupus familiaris (dog)0.031
Heat shock protein 75 kDa, mitochondrialHomo sapiens (human)1.496
Putative heat shock protein HSP 90-alpha A4Homo sapiens (human)0.78
Lysine-specific demethylase 4CHomo sapiens (human)0.7

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Anderson, KC; Hideshima, T; Ikeda, H; Ishitsuka, K; Jin, J; Kiziltepe, T; Moss, N; Ocio, EM; Okawa, Y; Pargellis, C; Podar, K; Raje, N; Richardson, PG; Vallet, S; Yasui, H1
Asantewaa, G; Ciesla, JH; Dewhurst, S; Harris, IS; Leach, J; Lutz, MM; Monaghan, M; Munger, J; Raymonda, MH; Schafer, XL; Smorodintsev-Schiller, LA; Takimoto, T1

Other Studies

2 other study(ies) available for birb 796 and tanespimycin

ArticleYear
BIRB 796 enhances cytotoxicity triggered by bortezomib, heat shock protein (Hsp) 90 inhibitor, and dexamethasone via inhibition of p38 mitogen-activated protein kinase/Hsp27 pathway in multiple myeloma cell lines and inhibits paracrine tumour growth.
    British journal of haematology, 2007, Volume: 136, Issue:3

    Topics: Antineoplastic Agents, Hormonal; Apoptosis; Benzoquinones; Boronic Acids; Bortezomib; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Cytotoxicity Tests, Immunologic; Dexamethasone; Drug Resistance, Neoplasm; HSP90 Heat-Shock Proteins; Humans; Immunoblotting; Interleukin-6; Intracellular Signaling Peptides and Proteins; Lactams, Macrocyclic; Multiple Myeloma; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrazines; Pyrazoles; Signal Transduction; Stem Cells; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2007
Pharmacologic profiling reveals lapatinib as a novel antiviral against SARS-CoV-2 in vitro.
    Virology, 2022, Volume: 566

    Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Benzoquinones; Cell Line; Chlorocebus aethiops; COVID-19; COVID-19 Drug Treatment; Drug Combinations; Drug Discovery; Drug Synergism; High-Throughput Screening Assays; Humans; Lactams, Macrocyclic; Lapatinib; Naphthalenes; Phenylurea Compounds; Pyrazoles; RNA, Viral; SARS-CoV-2; Vero Cells; Virus Replication

2022