Compounds > birb 796
Page last updated: 2024-09-04

birb 796 and purvalanol a

birb 796 has been researched along with purvalanol a in 2 studies

Compound Research Comparison

Studies
(birb 796)		Trials
(birb 796)		Recent Studies (post-2010)
(birb 796)		Studies
(purvalanol a)		Trials
(purvalanol a)		Recent Studies (post-2010) (purvalanol a)
13758086042

Protein Interaction Comparison

ProteinTaxonomybirb 796 (IC50)purvalanol a (IC50)
Cyclin-T1Homo sapiens (human)0.0497
G2/mitotic-specific cyclin-B2Homo sapiens (human)0.0193
Serine/threonine-protein kinase PAK 4Homo sapiens (human)0.13
G1/S-specific cyclin-E2Homo sapiens (human)0.035
Cyclin-dependent kinase 1Saccharomyces cerevisiae S288C0.08
Insulin receptorHomo sapiens (human)5
Cyclin-dependent kinase 1Homo sapiens (human)0.0968
Cyclin-dependent kinase 4Homo sapiens (human)0.6808
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)0.1833
G2/mitotic-specific cyclin-B1Homo sapiens (human)0.1026
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)9
Cyclin-A2Homo sapiens (human)0.0556
cAMP-dependent protein kinase catalytic subunit gammaHomo sapiens (human)9
cAMP-dependent protein kinase catalytic subunit betaHomo sapiens (human)9
G1/S-specific cyclin-D1Homo sapiens (human)0.85
G1/S-specific cyclin-E1Homo sapiens (human)0.035
Cyclin-dependent kinase 2Homo sapiens (human)0.0617
Mitogen-activated protein kinase 3 Homo sapiens (human)9
Cyclin-dependent kinase 7Homo sapiens (human)0.0497
Cyclin-dependent kinase 9Homo sapiens (human)0.0497
Cyclin-HHomo sapiens (human)0.0497
Cyclin-A1Homo sapiens (human)0.05
Cyclin-dependent-like kinase 5 Homo sapiens (human)0.0623
Dual specificity tyrosine-phosphorylation-regulated kinase 1AHomo sapiens (human)0.3
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)0.0623
Cdc2Patiria pectinifera0.27
G2/mitotic-specific cyclin-B3Homo sapiens (human)0.0193

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Cross, A; Edwards, SW; Glennon-Alty, L; Phoomvuthisarn, P; Wright, HL1

Other Studies

2 other study(ies) available for birb 796 and purvalanol a

ArticleYear
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
The CDK inhibitor purvalanol A induces neutrophil apoptosis and increases the turnover rate of Mcl-1: potential role of p38-MAPK in regulation of Mcl-1 turnover.
    Clinical and experimental immunology, 2018, Volume: 192, Issue:2

    Topics: Apoptosis; Cells, Cultured; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Healthy Volunteers; Humans; Monocytes; Myeloid Cell Leukemia Sequence 1 Protein; Naphthalenes; Neutrophils; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; Purines; Pyrazoles; Signal Transduction

2018