Compounds > birb 796
Page last updated: 2024-09-04

birb 796 and pf 3644022

birb 796 has been researched along with pf 3644022 in 1 studies

Compound Research Comparison

Studies
(birb 796)		Trials
(birb 796)		Recent Studies (post-2010)
(birb 796)		Studies
(pf 3644022)		Trials
(pf 3644022)		Recent Studies (post-2010) (pf 3644022)
1375801008

Protein Interaction Comparison

ProteinTaxonomybirb 796 (IC50)pf 3644022 (IC50)
Chain X, MAP kinase-activated protein kinase 2Homo sapiens (human)0.005
Chain X, MAP kinase-activated protein kinase 2Homo sapiens (human)0.005
Chain A, Cell division protein kinase 2Homo sapiens (human)0.005
Receptor-interacting serine/threonine-protein kinase 2Homo sapiens (human)0.59
Bile salt export pumpHomo sapiens (human)7
Cyclin-dependent kinase 1Homo sapiens (human)0.354
Serine/threonine-protein kinase pim-1Homo sapiens (human)0.088
Phosphorylase b kinase gamma catalytic chain, liver/testis isoformHomo sapiens (human)0.528
Tyrosine-protein kinase receptor UFOHomo sapiens (human)0.428
MAP kinase-activated protein kinase 2Homo sapiens (human)0.0955
Cyclin-dependent-like kinase 5 Homo sapiens (human)0.902
Tyrosine-protein kinase MerHomo sapiens (human)0.076
5'-AMP-activated protein kinase catalytic subunit alpha-1Homo sapiens (human)0.117
Calcium/calmodulin-dependent protein kinase type II subunit betaHomo sapiens (human)0.07
MAP kinase-activated protein kinase 3Homo sapiens (human)0.106
MAP kinase-activated protein kinase 5Homo sapiens (human)0.082
Serine/threonine-protein kinase BRSK2Homo sapiens (human)0.09
Serine/threonine-protein kinase BRSK1Homo sapiens (human)0.187
Mitogen-activated protein kinase kinase kinase 5Homo sapiens (human)0.06
MAP kinase-interacting serine/threonine-protein kinase 2Homo sapiens (human)0.148
Serine/threonine-protein kinase 17AHomo sapiens (human)0.071

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cunliffe, V; Frearson, J; Fujino, A; Gordon, R; Harris, CJ; Imai, M; Imaizumi, K; Kalloo-Hosein, H; Kambe, M; Kataoka, K; Kobayashi, S; Komatsu, K; Kosugi, T; Le, J; Makino, H; Matsueda, Y; Mitchell, DR; Oue, Y; Patel, G; Sakai, Y; Sherborne, B; Simpson, DJ; Sugiura, S; Suzuki, N; Takenouchi, O; Takimoto-Kamimura, M; Thomas, PS; Unoki, G; Yamakoshi, Y1

Other Studies

1 other study(ies) available for birb 796 and pf 3644022

ArticleYear
Mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2) as an antiinflammatory target: discovery and in vivo activity of selective pyrazolo[1,5-a]pyrimidine inhibitors using a focused library and structure-based optimization approach.
    Journal of medicinal chemistry, 2012, Aug-09, Volume: 55, Issue:15

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Crystallography, X-Ray; HSP27 Heat-Shock Proteins; Humans; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Models, Molecular; Phosphorylation; Protein Conformation; Protein Serine-Threonine Kinases; Pyrazoles; Pyrimidines; Shock, Septic; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2012