birb 796 has been researched along with niacinamide in 5 studies
| Studies (birb 796) | Trials (birb 796) | Recent Studies (post-2010) (birb 796) | Studies (niacinamide) | Trials (niacinamide) | Recent Studies (post-2010) (niacinamide) |
|---|---|---|---|---|---|
| 137 | 5 | 80 | 13,381 | 1,097 | 5,797 |
| Protein | Taxonomy | birb 796 (IC50) | niacinamide (IC50) |
|---|---|---|---|
| Chain A, NAD-dependent deacetylase | Thermotoga maritima | 1000 | |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | 3.3 | |
| NAD-dependent protein deacetylase sirtuin-2 | Homo sapiens (human) | 2.9 | |
| NAD-dependent protein deacetylase sirtuin-3, mitochondrial | Homo sapiens (human) | 8.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bukhtiyarova, M; Karpusas, M; Lee, Y; Namboodiri, HV; Ramcharan, J; Springman, EB | 1 |
| Dietrich, J; Hulme, C; Hurley, LH | 1 |
| Liu, H; Shen, Y; Yang, Y; Yao, X | 1 |
| Eriksson, LA; Gao, C; Grøtli, M | 1 |
| Biancheri, P; Foster, MR; Fyfe, MC; MacDonald, TT; Rowley, A; Sirohi, S; Solanke, Y; Walshe, CA; Webber, S; Wood, E | 1 |
5 other study(ies) available for birb 796 and niacinamide
| Article | Year |
|---|---|
Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases.
Topics: Benzamides; Benzenesulfonates; Crystallography, X-Ray; Humans; Imatinib Mesylate; Mitogen-Activated Protein Kinase 14; Models, Molecular; Molecular Structure; Naphthalenes; Niacinamide; Phenylurea Compounds; Piperazines; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-abl; Pyrazoles; Pyridines; Pyrimidines; Sorafenib; Structure-Activity Relationship | 2010 |
The design, synthesis, and evaluation of 8 hybrid DFG-out allosteric kinase inhibitors: a structural analysis of the binding interactions of Gleevec, Nexavar, and BIRB-796.
Topics: Adenosine Triphosphate; Allosteric Regulation; Amino Acid Sequence; Antineoplastic Agents; Benzamides; Benzenesulfonates; Catalytic Domain; Computer Simulation; Crystallography, X-Ray; Drug Design; Hydrogen Bonding; Imatinib Mesylate; Mitogen-Activated Protein Kinase 14; Naphthalenes; Niacinamide; Oligopeptides; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-abl; Pyrazoles; Pyridines; Pyrimidines; Sorafenib | 2010 |
Molecular dynamics simulation and free energy calculation studies of the binding mechanism of allosteric inhibitors with p38α MAP kinase.
Topics: Allosteric Regulation; Benzamides; Benzenesulfonates; Catalytic Domain; Humans; Imatinib Mesylate; Indenes; Mitogen-Activated Protein Kinase 14; Molecular Dynamics Simulation; Naphthalenes; Niacinamide; Phenylurea Compounds; Piperazines; Protein Conformation; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Pyrimidines; Sorafenib; Thermodynamics | 2011 |
Characterization of interactions and pharmacophore development for DFG-out inhibitors to RET tyrosine kinase.
Topics: Aminopyridines; Binding Sites; Humans; Indoles; Kinetics; Molecular Docking Simulation; Molecular Dynamics Simulation; Naphthalenes; Niacinamide; Oligonucleotides; Phenylurea Compounds; Protein Binding; Protein Conformation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-ret; Pyrazoles; Sorafenib; Structural Homology, Protein; Thermodynamics; Vascular Endothelial Growth Factor Receptor-2 | 2015 |
Effect of Narrow Spectrum Versus Selective Kinase Inhibitors on the Intestinal Proinflammatory Immune Response in Ulcerative Colitis.
Topics: Benzamides; Biopsy; Colitis, Ulcerative; Cytokines; Dasatinib; HT29 Cells; Humans; Interleukin-8; Leukocytes, Mononuclear; Macrophages; Mitogen-Activated Protein Kinase 14; Myofibroblasts; Naphthalenes; Niacinamide; Primary Cell Culture; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; src-Family Kinases; Syk Kinase | 2016 |