biotin has been researched along with s-adenosylmethionine in 31 studies
| Studies (biotin) | Trials (biotin) | Recent Studies (post-2010) (biotin) | Studies (s-adenosylmethionine) | Trials (s-adenosylmethionine) | Recent Studies (post-2010) (s-adenosylmethionine) |
|---|---|---|---|---|---|
| 14,847 | 95 | 3,882 | 1,179 | 72 | 814 |
| 14,847 | 95 | 3,882 | 5,987 | 198 | 1,872 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (19.35) | 18.7374 |
| 1990's | 3 (9.68) | 18.2507 |
| 2000's | 12 (38.71) | 29.6817 |
| 2010's | 9 (29.03) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Bogusiewicz, A; Boysen, G; Horvath, TD; Mock, DM; Stratton, SL | 1 |
| Heredia-Antúnez, A; Hernández-González, R; Hernández-Vázquez, A; Ibarra-González, I; Ortega-Cuellar, D; Pindolia, K; Velázquez-Arellano, A; Wolf, B | 1 |
| Bogusiewicz, A; Boysen, G; Mock, DM | 1 |
| Hagiwara, SI; Kagimoto, S; Kubota, M; Nambu, R | 1 |
| Mock, DM | 1 |
| Izumi, Y; Ogata, K; Tani, Y | 1 |
| Eisenberg, MA; Prakash, O | 1 |
| Eisenberg, MA; Stoner, GL | 2 |
| Eisenberg, MA | 1 |
| Schlenk, F | 1 |
| Bui, BT; Florentin, D; Izumi, Y; Marquet, A; Ohshiro, T; Yamamoto, M | 1 |
| Bui, BT; Florentin, D; Izumi, Y; Marquet, A; Ohshiro, T | 1 |
| Florentin, D; Guianvarc'h, D; Marquet, A; Nunzi, F; Tse Sum Bui, B | 1 |
| Jeltsch, A; Roth, M | 1 |
| Marquet, A | 1 |
| Fontecave, M; Hewitson, KS; Münck, E; Ollagnier-de Choudens, S; Roach, P; Sanakis, Y | 1 |
| Frederick, KK; Jarrett, JT; Ugulava, NB | 1 |
| Agrimi, G; Lasorsa, FM; Marobbio, CM; Palmieri, F | 1 |
| Berkovitch, F; Drennan, CL; Jarrett, JT; Nicolet, Y; Wan, JT | 1 |
| Cosper, MM; Hernández, HL; Huynh, BH; Jameson, GN; Johnson, MK; Krebs, C | 1 |
| Chatterjee, NP; Howitt, CL; Luan, L; Perkins, JB; Pero, JG; Van Arsdell, SW; Yocum, RR | 1 |
| Burkart, MD; Mercer, AC | 1 |
| Colombatto, S; Grillo, MA | 1 |
| Jeltsch, A; Liebert, K | 1 |
| Farrar, CE; Jarrett, JT | 1 |
| Fugate, CJ; Jarrett, JT | 1 |
| Cronan, JE; Lin, S | 1 |
| Magwamba, CC; Palittapongarnpim, P; Rukseree, K | 1 |
| Cramer, JD; Jarrett, JT | 1 |
| Anand, RS; Ganesan, D; Jayavelu, T; Rajasekaran, S; Selvam, S | 1 |
5 review(s) available for biotin and s-adenosylmethionine
| Article | Year |
|---|---|
Biotin: From Nutrition to Therapeutics.
Topics: Animals; Biotin; Biotinylation; Carnitine; Female; Gene Expression; Hormones; Humans; Multiple Sclerosis; Nutritional Status; Pregnancy; Pregnancy Complications; Streptavidin; Vitamin B Complex | 2017 |
Methylthioadenosine.
Topics: Adenosine; Animals; Biotin; Deoxyadenosines; Humans; Hydrolysis; Kinetics; Polyamines; Purine-Nucleoside Phosphorylase; S-Adenosylmethionine; T-Phages; Thionucleosides | 1983 |
Enzymology of carbon-sulfur bond formation.
Topics: Acetyltransferases; Anaerobiosis; Bacterial Proteins; Biotin; Cysteine; Enzymes; Intramolecular Transferases; Iron-Sulfur Proteins; Models, Chemical; S-Adenosylmethionine; Sulfur; Sulfurtransferases | 2001 |
S-adenosylmethionine and radical-based catalysis.
Topics: Acyltransferases; Animals; Biotin; Catalysis; Chemistry, Pharmaceutical; Coproporphyrinogen Oxidase; Dimerization; Escherichia coli; Free Radicals; Humans; Models, Chemical; Molybdenum; Ribonucleotide Reductases; S-Adenosylmethionine; Thioctic Acid | 2007 |
Biotin synthase: insights into radical-mediated carbon-sulfur bond formation.
Topics: Bacterial Proteins; Biocatalysis; Biotin; Carbon; Free Radicals; Fungal Proteins; Iron-Sulfur Proteins; Kinetics; Models, Molecular; Plants; S-Adenosylmethionine; Sulfur; Sulfurtransferases; Thermodynamics | 2012 |
1 trial(s) available for biotin and s-adenosylmethionine
| Article | Year |
|---|---|
Screening of carnitine and biotin deficiencies on tandem mass spectrometry.
Topics: Adolescent; Biomarkers; Biotin; Carnitine; Child; Child, Preschool; Dried Blood Spot Testing; Female; Humans; Infant; Male; Mass Screening; Nutritional Status; Prospective Studies; Tandem Mass Spectrometry | 2017 |
25 other study(ies) available for biotin and s-adenosylmethionine
| Article | Year |
|---|---|
Measurement of acylcarnitine substrate to product ratios specific to biotin-dependent carboxylases offers a combination of indicators of biotin status in humans.
Topics: Acetyl-CoA Carboxylase; Biomarkers; Biotin; Carbon-Carbon Ligases; Carbon-Nitrogen Ligases; Carnitine; Chromatography, Liquid; Deficiency Diseases; Glutarates; Humans; Methylmalonyl-CoA Decarboxylase; Reproducibility of Results; Substrate Specificity; Tandem Mass Spectrometry | 2012 |
Biotinidase knockout mice show cellular energy deficit and altered carbon metabolism gene expression similar to that of nutritional biotin deprivation: clues for the pathogenesis in the human inherited disorder.
Topics: Animals; Biotin; Biotinidase Deficiency; Blood Glucose; Body Weight; Carbon; Carnitine; Diet; Disease Models, Animal; Energy Metabolism; Gene Expression; Humans; Liver; Mice; Mice, Knockout; RNA, Messenger | 2013 |
In HepG2 cells, coexisting carnitine deficiency masks important indicators of marginal biotin deficiency.
Topics: Acyl Coenzyme A; Biomarkers; Biotin; Carnitine; Chromatography, Liquid; Culture Media; False Negative Reactions; Female; Hep G2 Cells; Humans; Pregnancy; Tandem Mass Spectrometry | 2015 |
Microbiological biosynthesis of biotin.
Topics: Acyltransferases; Amino Acids; Amino Acids, Diamino; Bacillus; Bacillus subtilis; Bacteria; Biotin; Coenzyme A Ligases; Ligases; Methods; Pimelic Acids; S-Adenosylmethionine; Saccharomyces cerevisiae; Transaminases | 1979 |
In vitro synthesis and and regulation of the biotin enzymes of Escherichia coli K-12.
Topics: Biotin; Carbon-Nitrogen Ligases; Cell-Free System; Enzyme Repression; Escherichia coli; Ligases; Operon; Peptide Synthases; S-Adenosylmethionine; Transaminases; Transcription, Genetic | 1978 |
Purification and properties of 7, 8-diaminopelargonic acid aminotransferase.
Topics: Amino Acids, Diamino; Biological Assay; Biotin; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Drug Stability; Escherichia coli; Hot Temperature; Hydroxyapatites; Keto Acids; Kinetics; Macromolecular Substances; Molecular Weight; Protamines; S-Adenosylmethionine; Time Factors; Transaminases | 1975 |
Mode of action of alpha-dehydrobiotin, a biotin analogue.
Topics: Amino Acids; Biotin; Carbon-Nitrogen Ligases; Enzyme Repression; Escherichia coli; Fatty Acids; Hybridization, Genetic; Keto Acids; Kinetics; Ligases; Mutation; Operon; S-Adenosylmethionine; Transaminases; Transcription, Genetic | 1975 |
Biosynthesis of 7,8-diaminopelargonic acid, a biotin intermediate, from 7-keto-8-aminopelargonic acid and S-adenosyl-L-methionine.
Topics: Adenosine; Adenosine Triphosphate; Amines; Amino Acids; Biotin; Cell-Free System; Chromatography, Paper; Culture Media; Electron Transport; Electrophoresis, Paper; Escherichia coli; Fatty Acids; Glucose; Keto Acids; Ketones; Magnesium; Methionine; S-Adenosylmethionine; Transaminases | 1971 |
Stimulatory factors for enzymatic biotin synthesis from dethiobiotin in cell-free extracts of Escherichia coli.
Topics: Bacillus; Biotin; Cell Extracts; Cysteine; Escherichia coli; Flavin-Adenine Dinucleotide; Immunosuppressive Agents; NAD; NADP; S-Adenosylmethionine | 1995 |
On the mechanism of biotin synthase of Bacillus sphaericus.
Topics: Bacillus; Biotin; Cysteine; S-Adenosylmethionine; Sulfurtransferases | 1994 |
Biotin synthase, a new member of the family of enzymes which uses S-adenosylmethionine as a source of deoxyadenosyl radical.
Topics: Bacillus; Biotin; Escherichia coli; Free Radicals; S-Adenosylmethionine; Sulfurtransferases | 1997 |
Biotin-avidin microplate assay for the quantitative analysis of enzymatic methylation of DNA by DNA methyltransferases.
Topics: Avidin; Biotin; DNA; DNA Methylation; DNA Modification Methylases; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific) | 2000 |
Reductive cleavage of S-adenosylmethionine by biotin synthase from Escherichia coli.
Topics: Biotin; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Kinetics; Methionine; Models, Chemical; Mutation; S-Adenosylmethionine; Spectroscopy, Mossbauer; Sulfurtransferases; Time Factors | 2002 |
Control of adenosylmethionine-dependent radical generation in biotin synthase: a kinetic and thermodynamic analysis of substrate binding to active and inactive forms of BioB.
Topics: Anaerobiosis; Binding Sites; Biotin; Catalysis; Dialysis; Enzyme Activation; Escherichia coli Proteins; Free Radicals; Iron-Sulfur Proteins; Kinetics; Oxidation-Reduction; Protein Conformation; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Substrate Specificity; Sulfurtransferases; Thermodynamics | 2003 |
Identification and functional reconstitution of yeast mitochondrial carrier for S-adenosylmethionine.
Topics: Biotin; Genes, Reporter; Membrane Transport Proteins; Mitochondria; Mitochondrial Proteins; Recombinant Fusion Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2003 |
Crystal structure of biotin synthase, an S-adenosylmethionine-dependent radical enzyme.
Topics: Amino Acid Motifs; Binding Sites; Biotin; Catalysis; Crystallization; Crystallography, X-Ray; Dimerization; Escherichia coli; Escherichia coli Proteins; Hydrogen; Hydrogen Bonding; Iron; Ligands; Models, Molecular; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; S-Adenosylmethionine; Sulfur; Sulfurtransferases | 2004 |
Characterization of the cofactor composition of Escherichia coli biotin synthase.
Topics: Anaerobiosis; Binding Sites; Biotin; Carbon-Sulfur Lyases; Coenzymes; Escherichia coli; Escherichia coli Proteins; Iron-Sulfur Proteins; Lyases; Pyridoxal Phosphate; Recombinant Proteins; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Spectroscopy, Mossbauer; Spectrum Analysis, Raman; Sulfurtransferases | 2004 |
Removing a bottleneck in the Bacillus subtilis biotin pathway: bioA utilizes lysine rather than S-adenosylmethionine as the amino donor in the KAPA-to-DAPA reaction.
Topics: Amino Acids; Amino Acids, Diamino; Bacillus subtilis; Bacterial Proteins; Biotin; Gene Expression Regulation, Bacterial; Lysine; Protein Engineering; Recombinant Proteins; S-Adenosylmethionine; Signal Transduction; Transaminases | 2005 |
Chemical expansion of cofactor activity.
Topics: Adenosine Triphosphate; Affinity Labels; Binding Sites; Biotin; Carbon; Coenzyme A; Coenzymes; Coumarins; DNA; Enzyme Activation; Methylation; Methyltransferases; Models, Chemical; Pyridoxal Phosphate; S-Adenosylmethionine; Tetrahydrofolates | 2006 |
Detection and quantitation of the activity of DNA methyltransferases using a biotin/avidin microplate assay.
Topics: Avidin; Biotin; DNA Methylation; DNA Modification Methylases; S-Adenosylmethionine | 2008 |
Protein residues that control the reaction trajectory in S-adenosylmethionine radical enzymes: mutagenesis of asparagine 153 and aspartate 155 in Escherichia coli biotin synthase.
Topics: Amino Acid Motifs; Asparagine; Aspartic Acid; Biotin; Catalysis; Escherichia coli; Escherichia coli Proteins; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; S-Adenosylmethionine; Sulfurtransferases | 2009 |
The BioC O-methyltransferase catalyzes methyl esterification of malonyl-acyl carrier protein, an essential step in biotin synthesis.
Topics: Adenosine; Adenosine Triphosphate; Amino Acid Sequence; Bacillus cereus; Bacterial Proteins; Biotin; Carrier Proteins; Chromatography, Gel; Conserved Sequence; Escherichia coli; Fatty Acids; Genetic Complementation Test; Hydrogen-Ion Concentration; Methionine; Molecular Sequence Data; Protein O-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 2012 |
Cloning, expression and characterization of histidine-tagged biotin synthase of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Biotin; Cloning, Molecular; Cysteine; Deoxyadenosines; Enzyme Inhibitors; Enzyme Stability; Histidine; Hydrogen-Ion Concentration; Kinetics; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Protein Engineering; Protein Multimerization; Recombinant Fusion Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity; Sulfurtransferases; Temperature | 2016 |
Purification, Characterization, and Biochemical Assays of Biotin Synthase From Escherichia coli.
Topics: Biotin; Enzyme Assays; Escherichia coli Proteins; Recombinant Proteins; S-Adenosylmethionine; Sulfurtransferases | 2018 |
Distinct utilization of biotin in and between adipose and brain during aging is associated with a lipogenic shift in Wistar rat brain.
Topics: Acetyl-CoA Carboxylase; Adipocytes; Adipose Tissue; Aging; Animals; Astrocytes; Biotin; Biotinylation; Brain; Cells, Cultured; Endoplasmic Reticulum Stress; Lipid Metabolism; Lipogenesis; Male; Rats; Rats, Wistar; S-Adenosylmethionine | 2020 |