biotin has been researched along with pyridoxal phosphate in 23 studies
| Studies (biotin) | Trials (biotin) | Recent Studies (post-2010) (biotin) | Studies (pyridoxal phosphate) | Trials (pyridoxal phosphate) | Recent Studies (post-2010) (pyridoxal phosphate) |
|---|---|---|---|---|---|
| 14,847 | 95 | 3,882 | 6,511 | 140 | 860 |
| Protein | Taxonomy | biotin (IC50) | pyridoxal phosphate (IC50) |
|---|---|---|---|
| P2X purinoceptor 1 | Homo sapiens (human) | 10 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (26.09) | 18.7374 |
| 1990's | 4 (17.39) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 6 (26.09) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Jakubowski, HV; McIntee, EJ; Richards, KA; Seiler, CL | 1 |
| Arab, L; Berlit, P; Bonjour, JP; Krause, KH; Kynast, G; Schmidt-Gayk, H | 1 |
| Aquino, H; Baker, H; Frank, O; Sorrell, MF; Thomson, AD | 1 |
| Gräser, H | 1 |
| Pai, CH | 1 |
| Hartman, RE | 1 |
| Keddie, RM; Owens, JD | 1 |
| Marquet, A; Ploux, O | 1 |
| Schmid, A; Schmid, H | 1 |
| Alexeev, D; Alexeeva, M; Baxter, RL; Campopiano, DJ; Sawyer, L; Webster, SP | 1 |
| Breyne, O; Carillon, S; Marquet, A; Ploux, O | 1 |
| Esaki, N; Mihara, H | 1 |
| Cosper, MM; Hernández, HL; Huynh, BH; Jameson, GN; Johnson, MK; Krebs, C | 1 |
| Burkart, MD; Mercer, AC | 1 |
| Amadasi, A; Bertoldi, M; Bettati, S; Borri-Voltattorni, C; Bossa, F; Cellini, B; Contestabile, R; di Salvo, ML; Mozzarelli, A | 1 |
| Abdel-Hamid, AM; Cronan, JE | 1 |
| Fukuwatari, T; Shibata, K; Wada, H | 1 |
| Mann, S; Ploux, O | 1 |
| Huo, L; Li, T; Liu, A; Pulley, C | 1 |
| Bi, L; Chen, G; Chen, T; Fan, S; Fleming, J; Li, DF; Wang, DC; Zhang, H; Zhang, XE; Zhou, J; Zhou, L; Zhou, Y | 1 |
| Aldrich, CC; Dai, R; Dawadi, S; Finzel, BC; Liu, F; Maize, KM; Park, SW; Schnappinger, D | 1 |
| Campopiano, DJ; Harrison, PJ; Herrera, MA; Ortiz, GP; Richardson, SM; Verez, R; Wang, M | 1 |
5 review(s) available for biotin and pyridoxal phosphate
| Article | Year |
|---|---|
[Possibilities and limitations of drugs to protect the liver].
Topics: Amino Acids; Animals; Biotin; Carnitine; Fructosediphosphates; Glucose; Immunologic Factors; Ketoglutaric Acids; Lipotropic Agents; Liver Diseases; Pyridoxal Phosphate; Sulfur | 1996 |
Bacterial cysteine desulfurases: their function and mechanisms.
Topics: Bacteria; Biotechnology; Biotin; Carbon-Sulfur Lyases; Coenzymes; Cyanobacteria; Lyases; Metalloproteins; Molybdenum Cofactors; Pteridines; Pyridoxal Phosphate; Sulfurtransferases; Thiamine | 2002 |
Pyridoxal 5'-phosphate enzymes as targets for therapeutic agents.
Topics: Alanine Racemase; Biotin; Carbon-Oxygen Lyases; Carboxy-Lyases; Drug Design; Enzymes; Glycine Hydroxymethyltransferase; Humans; Hydrolases; Intramolecular Transferases; Lyases; Pyridoxal Phosphate; Transaminases | 2007 |
Pyridoxal-5'-phosphate-dependent enzymes involved in biotin biosynthesis: structure, reaction mechanism and inhibition.
Topics: Acyltransferases; Biotin; Enzyme Inhibitors; Kinetics; Models, Molecular; Molecular Structure; Pyridoxal Phosphate; Transaminases | 2011 |
Decarboxylation mechanisms in biological system.
Topics: Amino Acids; Animals; Biotin; Carbohydrate Metabolism; Carboxy-Lyases; Decarboxylation; Flavins; Free Radicals; Metals; NAD; Pyridoxal Phosphate; Thiamine Pyrophosphate | 2012 |
18 other study(ies) available for biotin and pyridoxal phosphate
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Identification of new inhibitors for low molecular weight protein tyrosine phosphatase isoform B.
Topics: Enzyme Inhibitors; Humans; Molecular Docking Simulation; Neoplasms; Protein Conformation; Protein Isoforms; Protein Tyrosine Phosphatase, Non-Receptor Type 1 | 2013 |
B vitamins in epileptics.
Topics: Adult; Anticonvulsants; Biotin; Epilepsy; Erythrocytes; Female; Humans; Male; Pyridoxal Phosphate; Pyridoxine; Riboflavin; Risk; Sex Factors; Thiamine; Vitamin B 12 | 1986 |
In vivo and in vitro penetration of vitamins into human red blood cells.
Topics: Administration, Oral; Adult; Ascorbic Acid; Biological Assay; Biotin; Erythrocytes; Folic Acid; Humans; In Vitro Techniques; Injections, Intravenous; Male; Niacinamide; Nicotinic Acids; Pantothenic Acid; Pyridoxal Phosphate; Riboflavin; Thiamine; Vitamin B 12; Vitamins | 1971 |
[The cofactors of serine synthesis in primary root homogenates of Zea mays].
Topics: Adenosine Triphosphate; Biotin; Buffers; Chromatography; Electrophoresis; Folic Acid; NADP; Poaceae; Pyridoxal Phosphate; Serine; Vitamin B 12 | 1966 |
Biosynthesis of biotin: synthesis of 7,8-diaminopelargonic acid in cell-free extracts of Escherichia coli.
Topics: Amines; Biological Assay; Biotin; Cell-Free System; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Dialysis; Enzyme Repression; Escherichia coli; Fatty Acids; Ligases; Methionine; Mutation; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Spectrophotometry; Sulfates; Transaminases | 1971 |
Carbon dioxide fixation by extracts of Streptococcus faecalis var. liquefaciens.
Topics: Adenosine Triphosphate; Aspartic Acid; Bacteriological Techniques; Biotin; Carbon Dioxide; Carbon Isotopes; Centrifugation; Chromatography, Paper; Coenzyme A; Culture Media; Depression, Chemical; Dialysis; Enterococcus faecalis; Glutamates; Hydrogen-Ion Concentration; Ligases; Magnesium Sulfate; Mercaptoethanol; Ovalbumin; Oxaloacetates; Potassium Chloride; Pyridoxal Phosphate; Pyruvates; Sodium Chloride; Stimulation, Chemical | 1970 |
A note on the vitamin requirements of some coryneform bacteria from soil and herbage.
Topics: Arthrobacter; Bacteria; Biotin; Pantothenic Acid; Poaceae; Pyridoxal Phosphate; Riboflavin; Soil Microbiology; Thiamine; Vitamin B 12; Vitamin B Complex | 1968 |
Mechanistic studies on the 8-amino-7-oxopelargonate synthase, a pyridoxal-5'-phosphate-dependent enzyme involved in biotin biosynthesis.
Topics: Acyl Coenzyme A; Acyltransferases; Alanine; Bacillus; Biotin; Models, Chemical; Pyridoxal Phosphate; Recombinant Proteins | 1996 |
The crystal structure of 8-amino-7-oxononanoate synthase: a bacterial PLP-dependent, acyl-CoA-condensing enzyme.
Topics: Acyl Coenzyme A; Acyltransferases; Alanine; Amino Acid Sequence; Apoenzymes; Bacterial Proteins; Biotin; Catalytic Domain; Coenzyme A-Transferases; Crystallography, X-Ray; Dimerization; Enzyme Stability; Escherichia coli; Evolution, Molecular; Holoenzymes; Models, Molecular; Molecular Sequence Data; Protein Conformation; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Static Electricity | 1998 |
Slow-binding and competitive inhibition of 8-amino-7-oxopelargonate synthase, a pyridoxal-5'-phosphate-dependent enzyme involved in biotin biosynthesis, by substrate and intermediate analogs. Kinetic and binding studies.
Topics: Acyl Coenzyme A; Acyltransferases; Alanine; Aldehydes; Aminoethylphosphonic Acid; Biotin; Catalytic Domain; Dose-Response Relationship, Drug; Imines; Kinetics; Models, Chemical; Organophosphonates; Protein Conformation; Pyridoxal Phosphate; Stereoisomerism | 1999 |
Characterization of the cofactor composition of Escherichia coli biotin synthase.
Topics: Anaerobiosis; Binding Sites; Biotin; Carbon-Sulfur Lyases; Coenzymes; Escherichia coli; Escherichia coli Proteins; Iron-Sulfur Proteins; Lyases; Pyridoxal Phosphate; Recombinant Proteins; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Spectroscopy, Mossbauer; Spectrum Analysis, Raman; Sulfurtransferases | 2004 |
Chemical expansion of cofactor activity.
Topics: Adenosine Triphosphate; Affinity Labels; Binding Sites; Biotin; Carbon; Coenzyme A; Coenzymes; Coumarins; DNA; Enzyme Activation; Methylation; Methyltransferases; Models, Chemical; Pyridoxal Phosphate; S-Adenosylmethionine; Tetrahydrofolates | 2006 |
In vivo resolution of conflicting in vitro results: synthesis of biotin from dethiobiotin does not require pyridoxal phosphate.
Topics: Biotin; Escherichia coli; In Vitro Techniques; Pyridoxal Phosphate | 2007 |
Age-related alterations of B-group vitamin contents in urine, blood and liver from rats.
Topics: Age Factors; Aging; Animals; Biotin; Body Weight; Eating; Folic Acid; Liver; Male; Models, Animal; Niacinamide; Pyridoxal Phosphate; Rats; Tryptophan; Vitamin B 12; Vitamin B Complex | 2008 |
Structure and function of Mycobacterium smegmatis 7-keto-8-aminopelargonic acid (KAPA) synthase.
Topics: Amino Acids; Bacterial Proteins; Biotin; Catalytic Domain; Mycobacterium smegmatis; Pyridoxal Phosphate | 2015 |
Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Biocatalysis; Biotin; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Piperazines; Pyridoxal Phosphate; Structure-Activity Relationship; Transaminases | 2017 |
BioWF: A Naturally-Fused, Di-Domain Biocatalyst from Biotin Biosynthesis Displays an Unexpectedly Broad Substrate Scope.
Topics: Acyl Coenzyme A; Alanine; Bacterial Proteins; Biotin; Coenzyme A Ligases; Escherichia coli; Fatty Acids; Pyridoxal Phosphate; Substrate Specificity | 2022 |