Page last updated: 2024-09-05

biotin and desipramine

biotin has been researched along with desipramine in 7 studies

Compound Research Comparison

Studies
(biotin)
Trials
(biotin)
Recent Studies (post-2010)
(biotin)
Studies
(desipramine)
Trials
(desipramine)
Recent Studies (post-2010) (desipramine)
14,847953,8825,775487414

Protein Interaction Comparison

ProteinTaxonomybiotin (IC50)desipramine (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)9.18
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.35
Alpha-2A adrenergic receptorHomo sapiens (human)0.0003
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.35
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0034
Alpha-2B adrenergic receptorHomo sapiens (human)0.0003
Alpha-2C adrenergic receptorHomo sapiens (human)0.0003
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.35
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.0031
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)7.8
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.35
5-hydroxytryptamine receptor 1DRattus norvegicus (Norway rat)0.35
5-hydroxytryptamine receptor 1FRattus norvegicus (Norway rat)0.35
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.35
5-hydroxytryptamine receptor 6Rattus norvegicus (Norway rat)0.35
Histamine H1 receptorRattus norvegicus (Norway rat)0.0008
Sodium-dependent serotonin transporterHomo sapiens (human)0.1961
5-hydroxytryptamine receptor 7 Rattus norvegicus (Norway rat)0.35
5-hydroxytryptamine receptor 5ARattus norvegicus (Norway rat)0.35
5-hydroxytryptamine receptor 5BRattus norvegicus (Norway rat)0.35
5-hydroxytryptamine receptor 3ARattus norvegicus (Norway rat)0.35
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0003
Histamine H2 receptorCavia porcellus (domestic guinea pig)3.8
Sodium-dependent dopamine transporter Homo sapiens (human)9.9
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.4035
Sodium channel protein type 5 subunit alphaHomo sapiens (human)1.52
5-hydroxytryptamine receptor 4 Rattus norvegicus (Norway rat)0.35
5-hydroxytryptamine receptor 3BRattus norvegicus (Norway rat)0.35
Solute carrier family 22 member 2Rattus norvegicus (Norway rat)10
TransporterRattus norvegicus (Norway rat)7.8

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Klausa, G; Rörig, B; Sutor, B1
Huang, KX; Kecojevic, A; Koliatsos, VE; Welsh, AM; Zhou, L1
Balaban, CD; Halberstadt, AL1
Bubser, M; Deutch, AY; Kusnoor, SV1

Other Studies

7 other study(ies) available for biotin and desipramine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Beta-adrenoreceptor activation reduces dye-coupling between immature rat neocortical neurones.
    Neuroreport, 1995, Sep-11, Volume: 6, Issue:13

    Topics: Adrenergic beta-Agonists; Animals; Biotin; Cell Differentiation; Cellular Senescence; Cerebral Cortex; Coloring Agents; Desipramine; Female; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Neurons; Norepinephrine; Rats; Rats, Wistar

1995
Evidence that serotonin reuptake modulators increase the density of serotonin innervation in the forebrain.
    Journal of neurochemistry, 2006, Volume: 96, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Animals; Axons; Biotin; Desipramine; Dextrans; Fluorescent Dyes; Fluoxetine; Limbic System; Male; Neocortex; Nerve Endings; Nerve Fibers; Prosencephalon; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiazepines

2006
Selective anterograde tracing of nonserotonergic projections from dorsal raphe nucleus to the basal forebrain and extended amygdala.
    Journal of chemical neuroanatomy, 2008, Volume: 35, Issue:4

    Topics: 5,7-Dihydroxytryptamine; Adrenergic Uptake Inhibitors; Amygdala; Animals; Axons; Biotin; Brain Mapping; Desipramine; Dextrans; Dopamine Uptake Inhibitors; Efferent Pathways; Male; Medial Forebrain Bundle; Mesencephalon; Neurotoxins; Neurotransmitter Agents; Nomifensine; Raphe Nuclei; Rats; Rats, Long-Evans; Septal Nuclei; Staining and Labeling; Substantia Innominata

2008
The effects of nigrostriatal dopamine depletion on the thalamic parafascicular nucleus.
    Brain research, 2012, Mar-29, Volume: 1446

    Topics: Animals; Biotin; Corpus Striatum; Desipramine; Dextrans; Dopamine; Dopamine beta-Hydroxylase; Enzyme Inhibitors; Fluoresceins; Intralaminar Thalamic Nuclei; Male; Medial Forebrain Bundle; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase

2012