Page last updated: 2024-08-26

bimolane and razoxane

bimolane has been researched along with razoxane in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199015 (48.39)18.7374
1990's10 (32.26)18.2507
2000's1 (3.23)29.6817
2010's4 (12.90)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Ma, GJ; Wang, S; Wang, YP; Xue, KX1
Guo, Y; Lin, B; Lu, D; Xue, Y1
Bale, G; Chesney, TM; Noah, PW; Rosenberg, EW; Skinner, RB; Xu, B1
Chen, LJ; Liu, MZ; Wang, MY1
He, SQ; Li, CF; Liu, TF; Zhen, XY; Zhou, J1
Chen, YN; Fan, GC; Xia, SX; Zhang, YP1
Dan, N; Zhang, TM1
Li, GD; Liu, TX; Wang, MY; Zhang, TM1
Otter, GM; Ren, YF; Schmid, FA1
Creighton, AM; el-Hage, AN; Ferrans, VJ; Herman, EH; Witiak, DT1
He, SQ; Kim, JH; Kim, SH1
Fu, NW; Huang, KW; Ren, YF1
Liu, TF; Zhang, XF; Zhang, ZY2
Camerman, A; Camerman, N; Hempel, A1
Finch, M; Hellmann, K; Hutchinson, GE; Li, XT; Pym, BA1
Lin, C; Zhang, TM1
Chen, ZY; Lin, C; Zhang, TM1
Li, XF; Tu, ZH; Ye, H1
Ma, GJ; Wu, JZ; Xue, KX1
Gao, LS; Wang, XY; Zhang, MH1
Hua, HY; Zhang, TM; Zhang, Y1
Chen, SQ; Ma, GJ; Wu, JZ; Xue, KX1
Guo, Y; Xie, X; Xue, Y1
Eades, DM; Eastmond, DA; Frantz, CE; Grosovsky, AJ; Smith, H1
Bian, S; Li, D; Mi, Y; Wang, J; Wang, Y; Xue, Y1
Lu, DY; Lu, TR1
Eastmond, DA; Roy, SK1
Eastmond, DA; Hasegawa, LS; Vuong, MC1
Gu, Y; Li, K; Zhang, J; Zhou, Y1

Reviews

1 review(s) available for bimolane and razoxane

ArticleYear
Antimetastatic activities and mechanisms of bisdioxopiperazine compounds.
    Anti-cancer agents in medicinal chemistry, 2010, Volume: 10, Issue:7

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Transformed; Fibrinogen; Humans; Mice; Molecular Targeted Therapy; Neoplasm Metastasis; Piperazines; Razoxane

2010

Trials

1 trial(s) available for bimolane and razoxane

ArticleYear
Preliminary report on AT1727 as a potential radiosensitizer.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:12

    Topics: Clinical Trials as Topic; Combined Modality Therapy; Humans; Lung Neoplasms; Neoplasms; Piperazines; Radiation-Sensitizing Agents; Random Allocation; Razoxane; Sarcoma; Soft Tissue Neoplasms

1984

Other Studies

29 other study(ies) available for bimolane and razoxane

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
[Nuclear anomaly test in human lymphocytes in vitro].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:5

    Topics: Adult; Antineoplastic Agents; Cell Nucleus; Dose-Response Relationship, Drug; Female; Humans; Lymphocytes; Male; Micronucleus Tests; Mitomycin; Razoxane; Thiotepa

1992
Specific chromosomal translocations and therapy-related leukemia induced by bimolane therapy for psoriasis.
    Leukemia research, 1992, Volume: 16, Issue:11

    Topics: Adolescent; Adult; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Psoriasis; Razoxane; Translocation, Genetic; Treatment Outcome

1992
Efficacy of bimolane in the Malassezia ovalis model of psoriasis.
    The Journal of dermatology, 1991, Volume: 18, Issue:12

    Topics: Administration, Cutaneous; Administration, Oral; Animals; Betamethasone Valerate; Disease Models, Animal; Female; Injections, Intravenous; Malassezia; Methotrexate; Psoriasis; Rabbits; Razoxane; Skin

1991
[Reproductive toxicity of bimolane in mice and rabbits].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:6

    Topics: Animals; Antineoplastic Agents; Embryonic and Fetal Development; Female; Fetal Death; Fetal Resorption; Mice; Piperazines; Pregnancy; Rabbits; Razoxane

1989
Radiation survival properties of cultured human gastric adenocarcinoma cells and the effect of AT-1727.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:2

    Topics: Adenocarcinoma; Cell Survival; DNA Repair; Humans; In Vitro Techniques; Piperazines; Radiation-Sensitizing Agents; Razoxane; Stomach Neoplasms; Tumor Cells, Cultured

1989
[Relationship between radiation sensitization and DNA damage by bimolane].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1987, Volume: 8, Issue:2

    Topics: Animals; Antineoplastic Agents; Cross-Linking Reagents; DNA Damage; DNA, Neoplasm; Mice; Piperazines; Radiation-Sensitizing Agents; Razoxane; Sarcoma 180

1987
[Effects of bimolane on immune responses in mice].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1988, Volume: 9, Issue:5

    Topics: Animals; Antineoplastic Agents; Female; Hemolytic Plaque Technique; Hypersensitivity, Delayed; Male; Mice; Piperazines; Razoxane; Rosette Formation

1988
[Effects of bimolane and probimane on the incorporation of (3H)TdR, (3H)UR and (3H)Leu into Ehrlich ascites carcinoma cells iv vitro].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1988, Volume: 9, Issue:4

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Female; Leucine; Male; Mice; Piperazines; Razoxane; RNA, Neoplasm; Thymidine; Tumor Cells, Cultured; Uridine

1988
Further evaluation of bimolane and analogs as potential antitumor agents.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:4

    Topics: Animals; Drug Resistance; Female; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Osteosarcoma; Piperazines; Razoxane; Sarcoma 180

1985
Comparison of the protective effect of ICRF-187 and structurally related analogues against acute daunorubicin toxicity in Syrian golden hamsters.
    Research communications in chemical pathology and pharmacology, 1985, Volume: 48, Issue:1

    Topics: Animals; Body Weight; Cricetinae; Daunorubicin; Male; Mesocricetus; Piperazines; Razoxane; Stereoisomerism; Structure-Activity Relationship

1985
Interaction of radiation and AT 1727 in HeLa S-3 cells in culture.
    International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:6

    Topics: Antineoplastic Agents; Cell Survival; HeLa Cells; Humans; In Vitro Techniques; Piperazines; Razoxane

1985
[Effects of bimolane on size, metastases and cyclic AMP levels of Lewis lung carcinoma].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1984, Volume: 5, Issue:1

    Topics: Animals; Antineoplastic Agents; Cyclic AMP; Female; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Piperazines; Razoxane

1984
Phase II evaluation of AT-1727 in advanced human cancer.
    Chinese medical journal, 1983, Volume: 96, Issue:8

    Topics: Antineoplastic Agents; Drug Evaluation; Humans; Neoplasms; Piperazines; Razoxane

1983
Bimolane: structure determination indicates anticancer activity is attributable to ICRF-154.
    Science (New York, N.Y.), 1984, Sep-14, Volume: 225, Issue:4667

    Topics: Antineoplastic Agents; Models, Molecular; Piperazines; Razoxane; X-Ray Diffraction

1984
Effect of AT1727 on growth and metastasis of murine tumours.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:2

    Topics: Animals; Antineoplastic Agents; Drug Administration Schedule; Female; Leukemia L1210; Lung Neoplasms; Lymphoma; Male; Melanoma; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Piperazines; Razoxane; Sarcoma 180

1983
[The cytokinetic effects of bimolane (AT-1727) on S180 cells].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1982, Volume: 17, Issue:9

    Topics: Animals; Antineoplastic Agents; Cell Cycle; DNA, Neoplasm; Mice; Piperazines; Razoxane; Sarcoma 180

1982
[Pharmacological studies on bimolane (AT-1727), a new antineoplastic agent (author's transl)].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1980, Volume: 15, Issue:10

    Topics: Animals; Antineoplastic Agents; Dogs; Immunity; Mice; Neoplasms, Experimental; Piperazines; Rats; Razoxane

1980
[Leukemia associated with bimkolane].
    Zhonghua nei ke za zhi, 1994, Volume: 33, Issue:10

    Topics: Adolescent; Adult; Aged; Animals; Chromosome Aberrations; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Mice; Micronucleus Tests; Middle Aged; Psoriasis; Razoxane; Retrospective Studies

1994
[Effects of bimolane on cell cycle cytokinesis in human lymphocytes in vitro].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1994, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents; Cell Cycle; Cell Division; Cells, Cultured; Female; Humans; Lymphocytes; Male; Micronucleus Tests; Mitosis; Razoxane

1994
[140 cases of acute leukemia caused by bimolane].
    Zhonghua nei ke za zhi, 1993, Volume: 32, Issue:10

    Topics: Adult; Aged; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Psoriasis; Razoxane; Retrospective Studies

1993
Inhibitory effect of dioxopiperazine compounds on malondialdehyde formation induced by doxorubicin in rat liver mitochondria in vitro.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, Volume: 14, Issue:4

    Topics: Animals; Antineoplastic Agents; Chlorides; Doxorubicin; Edetic Acid; Ferric Compounds; In Vitro Techniques; Male; Malondialdehyde; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Razoxane

1993
[Mutagenic effects of bimolane].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1995, Volume: 16, Issue:6

    Topics: Animals; Antineoplastic Agents; Chromosome Aberrations; Mice; Mutagenicity Tests; Mutagens; Razoxane

1995
Translocation t(7;11)(P15;P15) in a patient with therapy-related acute myeloid leukemia following bimolane and ICRF-154 treatment for psoriasis.
    Leukemia research, 1997, Volume: 21, Issue:2

    Topics: Acute Disease; Adult; Antineoplastic Agents; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 7; Humans; Karyotyping; Leukemia, Myeloid; Male; Neoplasms, Second Primary; Psoriasis; Razoxane; Translocation, Genetic

1997
Bimolane: in vitro inhibitor of human topoisomerase II.
    Cancer letters, 1997, Dec-09, Volume: 120, Issue:2

    Topics: Antineoplastic Agents; DNA Topoisomerases, Type II; DNA, Kinetoplast; Enzyme Inhibitors; Humans; Mass Spectrometry; Razoxane; Substrate Specificity; Topoisomerase II Inhibitors

1997
Acute leukemia association with psoriasis: a report on 100 patients from a single center in China.
    American journal of hematology, 2010, Volume: 85, Issue:5

    Topics: Adult; Aged; China; Cohort Studies; Disease-Free Survival; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Nuclear Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Promyelocytic Leukemia Protein; Psoriasis; Radiation-Sensitizing Agents; Razoxane; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Transcription Factors; Tumor Suppressor Proteins; Young Adult

2010
Bimolane induces multiple types of chromosomal aberrations in human lymphocytes in vitro.
    Mutation research, 2011, Dec-24, Volume: 726, Issue:2

    Topics: Antineoplastic Agents; Cells, Cultured; Chromosome Aberrations; Humans; In Situ Hybridization, Fluorescence; Leukemia; Lymphocytes; Male; Micronuclei, Chromosome-Defective; Mutagens; Neoplasms, Second Primary; Nondisjunction, Genetic; Polyploidy; Razoxane

2011
A comparative study of the cytotoxic and genotoxic effects of ICRF-154 and bimolane, two catalytic inhibitors of topoisomerase II.
    Mutation research, 2013, Jan-20, Volume: 750, Issue:1-2

    Topics: Antineoplastic Agents; Cell Line; Cell Survival; Chromosome Aberrations; Cytokinesis; Humans; Lymphocytes; Micronucleus Tests; Mutagenicity Tests; Mutagens; Razoxane; Topoisomerase II Inhibitors

2013
Chronic myeloid leukaemia in a patient with psoriasis following bimolane treatment.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2020, Volume: 34, Issue:2

    Topics: Antineoplastic Agents; Dermatologic Agents; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Psoriasis; Razoxane

2020