bimatoprost and 3-hydroxybutanal

bimatoprost has been researched along with 3-hydroxybutanal* in 1 studies

Other Studies

1 other study(ies) available for bimatoprost and 3-hydroxybutanal

Article	Year
Synthesis of prostaglandin analogues, latanoprost and bimatoprost, using organocatalysis via a key bicyclic enal intermediate. Organic letters, 2015, Feb-06, Volume: 17, Issue:3 Two antiglaucoma drugs, bimatoprost and latanoprost, which are analogues of the prostaglandin, PGF2α, have been synthesized in just 7 and 8 steps, respectively. The syntheses employ an organocatalytic aldol reaction that converts succinaldehyde into a key bicyclic enal intermediate, which is primed for attachment of the required lower and upper side chains. By utilizing the crystalline lactone, the drug molecules were prepared in >99% ee. Topics: Aldehydes; Amides; Bimatoprost; Cloprostenol; Dinoprost; Latanoprost; Molecular Structure; Prostaglandins F, Synthetic; Prostaglandins, Synthetic	2015

Article

Year

Synthesis of prostaglandin analogues, latanoprost and bimatoprost, using organocatalysis via a key bicyclic enal intermediate.

Organic letters, 2015, Feb-06, Volume: 17, Issue:3

Two antiglaucoma drugs, bimatoprost and latanoprost, which are analogues of the prostaglandin, PGF2α, have been synthesized in just 7 and 8 steps, respectively. The syntheses employ an organocatalytic aldol reaction that converts succinaldehyde into a key bicyclic enal intermediate, which is primed for attachment of the required lower and upper side chains. By utilizing the crystalline lactone, the drug molecules were prepared in >99% ee.

Topics: Aldehydes; Amides; Bimatoprost; Cloprostenol; Dinoprost; Latanoprost; Molecular Structure; Prostaglandins F, Synthetic; Prostaglandins, Synthetic

2015