biguanides has been researched along with piperidines in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.33) | 18.7374 |
| 1990's | 10 (33.33) | 18.2507 |
| 2000's | 13 (43.33) | 29.6817 |
| 2010's | 6 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Britt, M; Paschetto, KA; Powel, RJ; Pullan, LM; Stumpo, RJ | 1 |
| Bell, J; Whitaker-Azmitia, PM; Zhang, XN | 1 |
| Canton, H; Colpaert, F; Lehmann, J | 1 |
| Dolecek, R | 1 |
| Bagga, L; Derks, M; Doyle, KM; Purcell, WM | 1 |
| Oblin, A; Schoemaker, H | 1 |
| Baudry, M; Marvizón, JC | 1 |
| Ashby, CR; Edwards, E; Hampton, E; Wang, RY; Zhang, J | 1 |
| Wiley, JL | 1 |
| Meyerhoff, JL; Repasi, RT; Rittase, WB; Staten, LD; Yourick, DL | 1 |
| Sharif, NA; Xu, SX | 1 |
| Akiyama, T; Inagaki, M; Kawada, T; Miyamoto, T; Shishido, T; Sugimachi, M; Sunagawa, K; Takaki, H; Uemura, K; Yamazaki, T | 1 |
| Mo, LL; Sundström, E | 1 |
| Inzucchi, SE | 1 |
| Gebka, J; Kaminska, E; Mikolajczak, P; Niedopad, L; Okulicz-Kozaryn, I; Polanska, A | 1 |
| Awe, SO; Harris, LC; LeDay, AM; Ohia, SE; Opere, CA; Sharif, NA | 1 |
| Morales, M; Oz, M; Zhang, L | 1 |
| Gibson, DA; Harris, BR; Littleton, JM; Rogers, DT | 1 |
| Awe, SO; Harris, LC; Kulkarni, K; LeDay, AM; Ohia, SE; Opere, CA; Sharif, NA | 1 |
| Bakalkin, G; Marinova, Z; Nakagawasai, O; Niijima, F; Sakurada, S; Sato, T; Satoh, S; Tadano, T; Takahashi, H; Tan-No, K; Terenius, L; Yakovleva, T | 1 |
| Antolínez de Abia, N; Melero Paredes, S | 1 |
| Ikeda, M; Matsumoto, S; Takeda, M; Tsutsui, Y | 1 |
| Bernard, JF; Hamon, M; Laguzzi, R; Mandjee, N; Netzer, F; Sévoz-Couche, C; Verberne, AJ | 1 |
| Longo, R | 1 |
| Ajdary, S; Ataee, R; Rezayat, M; Shahriari, S; Shokrgozar, MA; Zarrindast, MR | 1 |
| Barron, S; Bochi, GV; da Rosa, MM; Ferreira, J; Gomes, GM; Mello, CF; Rubin, MA | 1 |
| Bakris, GL; Flynn, C | 1 |
| Bär, J; Dalmolin, GD; Gomes, GM; Karpova, A; Kreutz, MR; Mello, CF; Rubin, MA | 1 |
| Kafi, F; Khakpai, F; Nasehi, M; Zarrindast, MR | 1 |
3 review(s) available for biguanides and piperidines
| Article | Year |
|---|---|
Oral antihyperglycemic therapy for type 2 diabetes: scientific review.
Topics: Administration, Oral; Biguanides; Blood Glucose; Carbamates; Chromans; Diabetes Mellitus, Type 2; Diet; Drug Therapy, Combination; Enzyme Inhibitors; Exercise; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Metformin; Piperidines; Randomized Controlled Trials as Topic; Sulfonylurea Compounds; Thiazoles; Thiazolidinediones; Troglitazone | 2002 |
Drugs for type 2 diabetes.
Topics: alpha-Galactosidase; Biguanides; Carbamates; Cyclohexanes; Diabetes Mellitus, Type 2; Drug Combinations; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Insulin; Nateglinide; Phenylalanine; Piperidines; Pyrazines; Sitagliptin Phosphate; Sulfonylurea Compounds; Thiazolidinediones; Triazoles | 2008 |
Noninsulin glucose-lowering agents for the treatment of patients on dialysis.
Topics: Adamantane; Biguanides; Diabetic Nephropathies; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Disease Progression; Glucagon-Like Peptides; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Linagliptin; Meglumine; Metformin; Nitriles; Piperidines; Purines; Pyrazines; Pyrrolidines; Quinazolines; Renal Dialysis; Renal Insufficiency, Chronic; Sitagliptin Phosphate; Sulfonylurea Compounds; Thiazolidinediones; Treatment Outcome; Triazoles; Uracil; Vildagliptin | 2013 |
27 other study(ies) available for biguanides and piperidines
| Article | Year |
|---|---|
Neomycin is an agonist at a polyamine site on the N-methyl-D-aspartate receptor.
Topics: Adrenergic alpha-Antagonists; Animals; Biguanides; Magnesium; Male; Neomycin; Phencyclidine; Piperazines; Piperidines; Polyamines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Synaptic Membranes; Tritium | 1992 |
5-HT3 receptor-active drugs alter development of spinal serotonergic innervation: lack of effect of other serotonergic agents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Biguanides; Female; Fenfluramine; Hypoglycemic Agents; Maternal-Fetal Exchange; Neurons; Pain; Paroxetine; Piperazines; Piperidines; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord; Tetrahydronaphthalenes; Tropanes | 1992 |
Glutamate and glycine co-activate while polyamines merely modulate the NMDA receptor complex.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic alpha-Antagonists; Animals; Biguanides; Binding, Competitive; Biogenic Polyamines; Biotransformation; Brain; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Kynurenic Acid; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1991 |
Ketotifen in the treatment of diabetics with various allergic conditions.
Topics: Biguanides; Blood; Diabetes Complications; Diabetes Mellitus; Drug Interactions; Female; Glucose Tolerance Test; Histamine H1 Antagonists; Humans; Hypersensitivity; Ketotifen; Male; Middle Aged; Piperidines; Sulfonylurea Compounds; Thiophenes | 1981 |
Histamine release from mast cells by polyamines: an NMDA receptor-mediated event?
Topics: Animals; Biguanides; Dizocilpine Maleate; Histamine Release; In Vitro Techniques; Kinetics; Mast Cells; p-Methoxy-N-methylphenethylamine; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Spermine | 1994 |
Complex allosteric modulation of the binding of the NMDA receptor antagonist [3H]CGP39653.
Topics: 2-Amino-5-phosphonovalerate; Allosteric Regulation; Animals; Biguanides; Binding Sites; Glycine; In Vitro Techniques; Kynurenic Acid; Male; Piperidines; Prosencephalon; Putrescine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine | 1994 |
[3H]dizocilpine association kinetics distinguish stimulatory and inhibitory polyamine sites of N-methyl-D-aspartate receptors.
Topics: Animals; Biguanides; Binding Sites; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Kinetics; Male; Piperidines; Polyamines; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine; Tritium | 1994 |
5-HT3-like receptors in the rat medial prefrontal cortex: further pharmacological characterization.
Topics: Animals; Biguanides; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Frontal Lobe; Glutamic Acid; Gyrus Cinguli; Hydrolysis; Indoles; Isomerism; Male; Neurons; Nicotinic Antagonists; Phosphatidylinositols; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tubocurarine | 1996 |
Nitric oxide synthase inhibitors attenuate phencyclidine-induced disruption of prepulse inhibition.
Topics: Acoustic Stimulation; Animals; Biguanides; Biogenic Polyamines; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Indazoles; Inhibition, Psychological; Male; Nitric Oxide Synthase; Nitroarginine; Phencyclidine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex, Startle | 1998 |
Ifenprodil and arcaine alter amygdala-kindling development.
Topics: Amygdala; Animals; Anticonvulsants; Biguanides; Brain; Dose-Response Relationship, Drug; Electric Stimulation; Injections, Intraventricular; Kindling, Neurologic; Male; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures | 1999 |
Human retina contains polyamine sensitive [3H]-ifenprodil binding sites: implications for neuroprotection?
Topics: Aged; Aged, 80 and over; Biguanides; Binding Sites; Excitatory Amino Acid Antagonists; Humans; N-Methylaspartate; Neuroprotective Agents; Piperidines; Polyamines; Receptors, N-Methyl-D-Aspartate; Retina | 1999 |
In vivo assessment of acetylcholine-releasing function at cardiac vagal nerve terminals.
Topics: Acetylcholine; Animals; Biguanides; Cats; Heart Conduction System; Heart Rate; Heart Ventricles; Hemicholinium 3; Microdialysis; Myocardium; Nerve Endings; Phenylephrine; Piperidines; Potassium; Potassium Chloride; Tetrodotoxin; Vagus Nerve | 2001 |
Polyamine and redox modulation of [3H]MK-801 binding to N-methyl-D-aspartate receptors in the spinal cord and cerebral cortex.
Topics: Animals; Biguanides; Cerebral Cortex; Dizocilpine Maleate; Hydrogen-Ion Concentration; Male; Neuroprotective Agents; Oxidation-Reduction; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine; Spinal Cord; Tritium | 2001 |
Effects of acamprosate and some polyamine site ligands of NMDA receptor on short-term memory in rats.
Topics: Acamprosate; Administration, Oral; Animals; Biguanides; Dose-Response Relationship, Drug; Drug Interactions; Male; Memory, Short-Term; Motor Activity; Piperidines; Polyamines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sleep; Spermidine; Taurine | 2002 |
Pharmacology of serotonin receptors modulating electrically-induced [3h]-norepinephrine release from isolated mammalian iris-ciliary bodies.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biguanides; Cattle; Ciliary Body; Dose-Response Relationship, Drug; Electric Stimulation; Humans; In Vitro Techniques; Iris; Norepinephrine; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Tritium; Tropanes | 2002 |
Endogenous cannabinoid, anandamide, acts as a noncompetitive inhibitor on 5-HT3 receptor-mediated responses in Xenopus oocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Analysis of Variance; Animals; Arachidonic Acids; Biguanides; Cannabinoids; Chelating Agents; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electrophysiology; Endocannabinoids; Enzyme Inhibitors; Female; Indazoles; Membrane Potentials; Oocytes; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Serotonin, 5-HT3; Rimonabant; RNA, Complementary; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin Receptor Agonists; Thionucleotides; Tropanes; Xenopus laevis | 2002 |
Radioligand binding studies reveal agmatine is a more selective antagonist for a polyamine-site on the NMDA receptor than arcaine or ifenprodil.
Topics: Agmatine; Animals; Biguanides; Binding Sites; Binding, Competitive; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Tritium | 2002 |
Glucose-deprivation-induced [3H]D-aspartate release from isolated bovine and human retinae.
Topics: Alanine; Animals; Biguanides; Calcium Channel Blockers; Cattle; D-Aspartic Acid; Diltiazem; Dizocilpine Maleate; Drug Synergism; Glucose; Glutamic Acid; Glycine; Humans; Kainic Acid; N-Methylaspartate; Nitrendipine; omega-Conotoxins; Perfusion; Piperidines; Polyamines; Receptors, Glutamate; Retina; Tritium; Verapamil | 2003 |
Pronociceptive role of dynorphins in uninjured animals: N-ethylmaleimide-induced nociceptive behavior mediated through inhibition of dynorphin degradation.
Topics: Agmatine; Analysis of Variance; Animals; Behavior, Animal; Biguanides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Dynorphins; Enkephalins; Enzyme Inhibitors; Ethylmaleimide; Excitatory Amino Acid Antagonists; Immune Sera; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Narcotics; Nociceptin Receptor; Piperidines; Protein Precursors; Receptors, Opioid; Spinal Cord; Time Factors | 2005 |
[Oral anti-diabetes medicines, an update].
Topics: Administration, Oral; Biguanides; Body Mass Index; Contraindications; Diabetes Mellitus; Humans; Hypoglycemic Agents; Motivation; Obesity; Piperidines; Sulfonylurea Compounds; Trisaccharides | 2008 |
Excitability of small-diameter trigeminal ganglion neurons by 5-HT is mediated by enhancement of the tetrodotoxin-resistant sodium current due to the activation of 5-HT(4) receptors and/or by the inhibition of the transient potassium current.
Topics: Aniline Compounds; Animals; Animals, Newborn; Antibodies, Heterophile; Biguanides; Biophysics; Cells, Cultured; Dose-Response Relationship, Drug; Electric Stimulation; Indoles; Membrane Potentials; Neurons; Patch-Clamp Techniques; Piperidines; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sodium Channel Blockers; Tetrodotoxin; Trigeminal Ganglion; Tropisetron | 2008 |
Inhibition of the bradycardic component of the von Bezold-Jarisch reflex and carotid chemoreceptor reflex by periaqueductal gray stimulation: involvement of medullary receptors.
Topics: Animals; Bicuculline; Biguanides; Bradycardia; Carotid Arteries; Chemoreceptor Cells; GABA Antagonists; Granisetron; Immunohistochemistry; Male; Microinjections; Parasympathetic Nervous System; Periaqueductal Gray; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Neurokinin-1; Receptors, Serotonin, 5-HT3; Reflex; Serotonin Agents; Solitary Nucleus; Sympathetic Nervous System; Tetrazoles | 2009 |
Diabetes under control: Understanding oral antidiabetic agents.
Topics: Administration, Oral; Biguanides; Carbamates; Cyclohexanes; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Combinations; Drug Therapy, Combination; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Nateglinide; Phenylalanine; Piperidines; Sulfonylurea Compounds | 2010 |
Study of 5HT3 and HT4 receptor expression in HT29 cell line and human colon adenocarcinoma tissues.
Topics: Adenocarcinoma; Aminobenzoates; Biguanides; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cell Proliferation; Cisapride; Colonic Neoplasms; HT29 Cells; Humans; Oxazines; para-Aminobenzoates; Piperidines; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists | 2010 |
Polyaminergic agents modulate contextual fear extinction in rats.
Topics: Animals; Biguanides; Conditioning, Classical; Excitatory Amino Acid Antagonists; Extinction, Psychological; Fear; Freezing Reaction, Cataleptic; Male; Neuropsychological Tests; Nootropic Agents; Piperidines; Polyamines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermidine | 2010 |
Inhibition of the polyamine system counteracts β-amyloid peptide-induced memory impairment in mice: involvement of extrasynaptic NMDA receptors.
Topics: Amyloid beta-Peptides; Animals; Biguanides; Binding Sites; Cell Nucleus; Dendritic Spines; Exploratory Behavior; Hippocampus; Male; Memory Disorders; Mice; Nerve Tissue Proteins; Peptide Fragments; Piperidines; Polyamines; Receptors, N-Methyl-D-Aspartate; Spermidine; Synapses | 2014 |
Involvement of the serotonergic system of the ventral hippocampus (CA3) on amnesia induced by ACPA in mice.
Topics: Amnesia; Aniline Compounds; Animals; Arachidonic Acids; Biguanides; Bridged Bicyclo Compounds, Heterocyclic; CA3 Region, Hippocampal; Cannabinoid Receptor Agonists; Catheters, Indwelling; Male; Mice; Oxazines; para-Aminobenzoates; Piperidines; Receptor, Cannabinoid, CB1; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2015 |