Page last updated: 2024-08-17

biguanides and phenformin

biguanides has been researched along with phenformin in 153 studies

Research

Studies (153)

Timeframe	Studies, this research(%)	All Research%
pre-1990	128 (83.66)	18.7374
1990's	6 (3.92)	18.2507
2000's	4 (2.61)	29.6817
2010's	15 (9.80)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hedner, U; Nilsson, IM	1
Januszko, J	1
Biron, P	2
Schwandt, P; Weisweiler, P	1
Eggstein, M; Luft, D; Schmülling, RM	1
Giulietti, M	1
Berger, W	1
Offerhaus, L	1
Irsigler, K; Kaspar, L; Kritz, H; Regal, H	1
Teijgeler, CA; van Gestel, WJ	1
Michalska, L; Nagel, G; Wróbel, J	1
Goebel, R; Pilger, E; Schmid, P	2
Aro, A; Idänpään-Heikkilä, J; Korhonen, T	1
Kowalik-Borówka, E; Tatoń, J	1
Cohen, RD; Iles, RA	1
Althoff, PH; Fassbinder, W; Koch, KM; Neubauer, M; Schöffling, K	1
Aro, A	1
Alberti, KG; Nattrass, M	1
Bartosiewicz, W; Czyzyk, A; Lao, B; Orlowska, K; Szczepanik, Z	1
Morgan, DB; Wales, JK; Waters, AK	1
Assan, R; Girard, JR; Heuclin, C	1
Foltin, E; Irsigler, K; Kritz, H; Regal, H	1
Bartosiewicz, W; Czyzyk, A; Lao, B; Orłowska, K; Szczepanik, Z	1
Kimbel, KH	1
Bridi, G; Tutwiler, GF	1
Bolzano, K	1
Bruneder, H; Klein, HJ	1
Bressler, R; Shen, SW	1
Sauer, H; Schneider, B	1
Froesch, ER	1
Pain, RW; Phillips, PJ	1
Luft, D; Müller, PH	1
Butt, H; Reitinger, J	1
Caspary, WF; Deuticke, U; Emrich, D; Reimold, W; Willms, B; Zavada, I	1
Isnard, F; Lavieuville, M	1
Botha, JL; Jackson, WP; Vinik, AI	1
Rodger, NW	1
Amft, R; Buschmann, HJ; Dissmann, W; Thimme, W	1
Hamada, C; Kojima, S; Tanaka, R	1
Jerums, G	1
Ennis, G	1
Förster, H	1
Berger, W; Heierli, C; Mehnert-Aner, S; Mülly, K; Ritz, R	1
Forsham, PH; Karam, JH; Matin, SB	1
Czyzyk, A	2
Forshan, PH; Karam, JH; Matin, SB	1
Bershteĭn, LM; Bobrov, IuF; Dil'man, VM; Kovaleva, IG; Tsyrlina, EV	1
Assan, R; Heuclin, C; Pene, F; Savouret, JF	1
Assan, R; Attali, JR; Girard, JR; Heuclin, C	1
Madhavan, R; Sankaran, JR; Seshasaianam, C; Seshiah, V; Shanker, R; Sundaram, A; Venkataraman, S	1
Aguilar, C; García, JE; Reza, A; Rull, JA	1
Lockwood, TD; Thorne, DP	1
Bowden, CR; Jordan, AD; Marchione, CS; Maryanoff, BE; Reitz, AB; Tuman, RW	1
Liang, JZ; Luo, ZT; Yang, DP	1
Chakrabarti, R; Fearnley, GR; Hocking, ED	1
Scoville, AB	1
Mughini, L; Polosa, P	1
Kono, N; Tarui, S	1
Corsini, GU; Muntoni, S; Sirigu, F; Tagliamonte, P	2
Carr, S; Davidoff, F	1
Hermann, LS	1
Muntoni, S	1
Katsilambros, N; Nierle, C; Pfeiffer, EE; Schatz, H	1
Jahn, P; Kraaz, W; Loge, O; Losert, W; Schillinger, E	2
Babiński, S; Giermaziak, H	1
Gries, FA; Koschinsky, T; Vogelberg, KH	1
Berthe, G; Donadieu, AM; Lohier, P; Loiseau, G; Marquet, JP; Millischer, R	1
Beckmann, R	3
Lopis, S; Schneider, T	1
Mehnert, H	1
Cucurachi, L; Cucurachi, P; Dell'Anna, A; Strata, A; Zuliani, U	1
Gubergrits, AIa; Lesnichiĭ, AV; Shevchenko, IV	1
Back, N; Barlow, B; Czarnecki, J; Wilkens, H	1
Schöffling, K	1
Shaw, SR; Wickramasinghe, JA	1
Garrett, ER; Tsau, J	1
Garrett, ER; Hinderling, PH; Tsau, J	1
Fearnley, GR	2
Bianchini, P; Bramanti, G; De Fina, V; Dell'Omodarme, G	1
Liashko, KIa; Oganesova, VT	1
Lao, B; Okniński, W	1
Fövényi, J	1
Abramson, EA; Arky, RA	1
Chakrabarti, R; Evans, J; Fearnley, GR; Hocking, ED	1
Barbui, T; Campanacci, L; Di Luzio, V; Guarnieri, GF; Palmari, V; Previato, G	1
Laastuen, L; Todd, WR	1
Bewsher, PD; Stowers, JM	1
Haeckel, H; Haeckel, R	1
Dérot, M; Rathery, H; Rathery, M	1
Ricketts, HT	1
Dhirawani, MK; Doshi, JC; Patel, JC	1
Stötter, G	1
Böttcher, M; Söling, HD; Willms, B; Zahlten, R	1
Jangaard, NO; Pereira, JN; Pinson, R	1
Davidoff, F	1
Tatoń, J	1
Tibbs, RC	1
Haese, E	1
Berger, W; Constam, GR; Siegenthaler, W	1
Saito, T; Yoshida, S	1
Tomás Vert, F; Trejueque Monge, J; Vicente-Pedrós, F	1
Boberg, M; Killander, A	1
Lunetta, M; Mughini, L; Mughini, MT; Presti, C	1
Adams, JF; Clark, JS; Ireland, JT; Kesson, CM; Watson, WS	1
Hedner, U; Nilsson, IM; Tengborn, L	1
Goldfine, ID; Pezzino, V; Vigneri, R; Wong, KY	1
Cicmir, I; Heggen, ME; Vogelberg, KH	1
Aro, A; Huttunen, JK; Järvinen, R; Juvonen, H; Korhonen, T; Palomäki, P; Ritala, P; Siitonen, O	1
Chen, S; Stucki, JW; Ubl, JJ	1
Rojas Hidalgo, E	1
McNeill, JH; Orvig, C; Thompson, KH; Woo, LC; Yuen, VG	1
Kuroda, A; Yamasaki, Y	1
Inoue, T; Kira, K; Nagakura, T; Saeki, T; Tanaka, I; Yamazaki, K; Yasuda, N	1
CREUTZFELDT, W; SOELING, HD; WERCHAU, H	1
AKAZAWA, Y	1
CUTTING, W	1
CREMER, G; DEUIL, R	1
CIEPLIK, U; GRAUPNER, K; WIEZOREK, WD	1
PASSERI, M; TONELLI, M	1
SCHAEFER, G	1
PREJAC, M	1
ANOSOVA, LN; MOSKOVICH, EG; ZEFIROVA, GS	1
CASTELLAZZI, R; FIORIO, C	1
OKER, C	1
CARLETTI, D	1
Cai, Y; Finsi, J; Heimberg, H; Hinke, SA; Martens, GA; Pipeleers, D; Van de Casteele, M	1
Iwatsubo, T; Kamimura, H; Noguchi, K; Umehara, KI	1
Kitamura, A; Komuro, S; Sogame, Y; Yabuki, M	1
Beauchamp, MC; Gotlieb, WH; Pollak, M; Rosenblatt, J; Segal, ED; Yasmeen, A	1
Birnbaum, MJ; Chu, Q; Foretz, M; Miller, RA; Viollet, B; Xie, J	1
Brejchova, J; Cahova, M; Cervinkova, Z; Drahota, Z; Endlicher, R; Kalous, M; Kazdova, L; Milerova, M; Palenickova, E; Svoboda, P; Vosahlikova, M	1
Bazelier, MT; de Vries, F; Dittrich, ST; Henry, RM; Knapen, LM; Neef, C; Starup-Linde, J; Stolk, LM; Vestergaard, P	1
Bayraktar, EC; Birsoy, K; Chen, WW; Clish, CB; Lorbeer, FK; Possemato, R; Sabatini, DM; Thiru, P; Wang, T; Yucel, B	1
Asara, JM; German, NJ; Gonzalez-Herrera, KN; Haigis, MC; Janzer, A; Struhl, K	1
Birman, E; Blouin, MJ; Gravel, SP; Hulea, L; Pollak, M; St-Pierre, J; Toban, N; Topisirovic, I; Zakikhani, M; Zhao, Y	1
Andreeff, M; Bornmann, W; Duque, JE; Enciso, L; Jaramillo, D; Konopleva, M; Krystal, G; Lee, JT; Lopez, C; Morales, L; Pan, R; Samudio, I; Suarez, M; Velez, J	1
Agip, AN; Bridges, HR; Hirst, J; Sirviö, VA	1
Langmaier, J; Pižl, M; Samec, Z; Záliš, S	1
Lin, HK; Zhang, X	1
Alan, L; Drahota, Z; Houstek, J; Kovalcikova, J; Kovarova, N; Mracek, T; Pecina, P; Pecinova, A; Zima, M	1
desBORDES, C; Kim, H; Lea, MA	1
Hébrant, M; Herzog, G; Hussin, MH; Jajuli, MN; Rahim, AA; Saad, B	1

Reviews

16 review(s) available for biguanides and phenformin

Article	Year
[Lactic acidosiss as a consequence of treatment with biguanide derivatives]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1979, May-15, Volume: 32, Issue:10 Topics: Acidosis; Biguanides; Diabetes Mellitus; Humans; Hydrogen-Ion Concentration; Insulin; Lactates; Models, Biological; Phenformin	1979
Lactic acidosis in biguanide-treated diabetics: a review of 330 cases. Diabetologia, 1978, Volume: 14, Issue:2 Topics: Acidosis; Biguanides; Buformin; Diabetes Complications; Diabetes Mellitus; Humans; Hypoglycemic Agents; Lactates; Metformin; Phenformin	1978
Oral hypoglycemic agents. Disease-a-month : DM, 1976, Volume: 22, Issue:4 Topics: Administration, Oral; Animals; Biguanides; Clinical Trials as Topic; Diabetes Mellitus; Drug Interactions; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Lipid Metabolism; Phenformin; Risk; Stimulation, Chemical; Sulfonylurea Compounds	1976
[What is achieved by the therapy with oral antidiabetics?]. Der Internist, 1976, Volume: 17, Issue:12 Topics: Administration, Oral; Adult; Biguanides; Chlorpropamide; Diabetes Mellitus; Diabetic Angiopathies; Drug Interactions; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Obesity; Phenformin; Prospective Studies; Retrospective Studies	1976
Antidiabetic drugs after the University Group Diabetes Program (UGDP). Annual review of pharmacology, 1975, Volume: 15 Topics: Acidosis; Biguanides; Diabetes Mellitus; Drug Interactions; Hemodynamics; Hypoglycemic Agents; Islets of Langerhans; Lactates; Phenformin; Sulfonylurea Compounds	1975
[Effects and adverse effects of antidiabetic derivatives of biguanide]. Die Medizinische Welt, 1975, Oct-17, Volume: 26, Issue:42 Topics: Biguanides; Blood Glucose; Chemical Phenomena; Chemistry; Diabetes Mellitus; Duodenum; Gastrointestinal Motility; Glucagon; Glucose; Growth Hormone; Humans; Insulin; Intestinal Absorption; Lactates; Phenformin	1975
[Biguanide--its mechanism of action and indication]. Nihon rinsho. Japanese journal of clinical medicine, 1969, Volume: 27, Issue:8 Topics: Adenosine Triphosphate; Animals; Biguanides; Blood Glucose; Diabetes Mellitus; Glucose; Guinea Pigs; Haplorhini; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Kinetics; Phenformin; Phosphofructokinase-1; Rabbits; Rats; Respiration	1969
Biguanides and lactate metabolism: a review. Danish medical bulletin, 1973, Volume: 20, Issue:3 Topics: Acidosis; Animals; Biguanides; Blood Glucose; Carbon Radioisotopes; Diabetes Mellitus; Gluconeogenesis; Guanidines; Humans; Hyperglycemia; Hypoglycemia; Lactates; Phenformin; Physical Exertion; Pyruvates; Rats	1973
Inhibition of fatty acid oxidation by biguanides: implications for metabolic physiopathology. Advances in lipid research, 1974, Volume: 12, Issue:0 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adipose Tissue; Animals; Biguanides; Biological Transport; Carbon Dioxide; Carbon Radioisotopes; Diabetes Mellitus, Experimental; Fatty Acids; Gluconeogenesis; Glycerol; Glycogen; Guinea Pigs; Humans; Hyperlipidemias; Insulin; Liver; Malate Dehydrogenase; Muscles; Oxidation-Reduction; Perfusion; Phenformin; Pyruvate Carboxylase; Rats; Species Specificity	1974
[On the mechanism of action of biguanides in man]. Arzneimittel-Forschung, 1969, Volume: 19, Issue:4 Topics: Adrenal Glands; Arteries; Biguanides; Blood Glucose; Depression, Chemical; Diabetes Mellitus; Glucose; Humans; Insulin; Lactates; Liver; Muscles; Nitrogen; Oxidation-Reduction; Pancreas; Phenformin; Phosphates; Potassium; Pyruvates; Stimulation, Chemical; Veins	1969
[Pharmacokinetics of blood glucose lowering biguanide derivatives]. Acta diabetologica latina, 1969, Volume: 6 Suppl 1 Topics: Animals; Biguanides; Blood Glucose; Guinea Pigs; Humans; Hypoglycemic Agents; Kinetics; Metformin; Mice; Phenformin; Protein Binding; Rabbits; Rats; Species Specificity; Time Factors; Tritium	1969
[The effect of different hypoglycemic preparations on the state of the functions and morphology of the liver in diabetes mellitus]. Terapevticheskii arkhiv, 1971, Volume: 43, Issue:12 Topics: Adult; Aged; Biguanides; Chemical and Drug Induced Liver Injury; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Phenformin; Sulfanilamides	1971
[Behavior of lactate and pyruvate in diabetics during ambulatory treatment with biguanides or with a combination of biguanides and sulfonylureas. II]. La Clinica terapeutica, 1980, Jun-30, Volume: 93, Issue:6 Topics: Aged; Ambulatory Care; Biguanides; Diabetes Mellitus; Diabetic Ketoacidosis; Drug Combinations; Female; Glyburide; Humans; Lactates; Male; Metformin; Middle Aged; Phenformin; Pyruvates; Sulfonylurea Compounds	1980
[Antidiabetic biguanides and lactic acidosis]. Revista clinica espanola, 1997, Volume: 197, Issue:8 Topics: Acidosis, Lactic; Biguanides; Buformin; Diabetes Mellitus; Humans; Hypoglycemic Agents; Models, Biological; Phenformin; Sulfonylurea Compounds	1997
[Adverse effect of biguanides]. Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 9 Topics: Acidosis, Lactic; Biguanides; Diabetes Mellitus, Type 2; Gastrointestinal Diseases; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Phenformin; Vitamin B 12 Deficiency	2002
[BIGUANIDES IN THE ORAL THERAPY OF DIABETES MELLITUS]. Lijecnicki vjesnik, 1963, Volume: 85 Topics: Biguanides; Diabetes Mellitus; Guanidines; Hypoglycemic Agents; Phenformin	1963

Trials

11 trial(s) available for biguanides and phenformin

Article	Year
Diabetic hearts and biguanides. Canadian Medical Association journal, 1975, Aug-09, Volume: 113, Issue:3 Topics: Animals; Biguanides; Canada; Cardiovascular Diseases; Clinical Trials as Topic; Cyclic AMP; Diabetes Mellitus; Female; Humans; Male; Metformin; Phenformin; Placebos; Prospective Studies; Retrospective Studies	1975
[Treatment of primary hyperlipoproteinemias type IV with different biguanides (author's transl)]. Klinische Wochenschrift, 1976, Mar-15, Volume: 54, Issue:6 Topics: Biguanides; Buformin; Cholesterol; Female; Humans; Hyperlipidemias; Lipoproteins, VLDL; Male; Metformin; Middle Aged; Phenformin; Triglycerides	1976
[The risk of lacticate acidosis: a comparison of the 3 biguanides in treatment of diabetics (authors' transl)]. Wiener klinische Wochenschrift, 1978, May-12, Volume: 90, Issue:10 Topics: Acidosis; Biguanides; Buformin; Diabetes Mellitus; Exercise Test; Female; Humans; Lactates; Male; Metformin; Phenformin; Risk	1978
Oral hypoglycemic agents. Disease-a-month : DM, 1976, Volume: 22, Issue:4 Topics: Administration, Oral; Animals; Biguanides; Clinical Trials as Topic; Diabetes Mellitus; Drug Interactions; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Lipid Metabolism; Phenformin; Risk; Stimulation, Chemical; Sulfonylurea Compounds	1976
Association of lactic acidosis with biguanide therapy. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Aug-13, Volume: 52, Issue:8 Topics: Biguanides; Buformin; Depression, Chemical; Diabetes Mellitus; Humans; Lactates; Metabolic Clearance Rate; Metformin; Phenformin	1977
Fibrinolytic effects of diguanides plus ethyloestrenol in occlusive vascular disease. Lancet (London, England), 1967, Nov-11, Volume: 2, Issue:7524 Topics: Adult; Aged; Angina Pectoris; Biguanides; Blood Coagulation Tests; Cholesterol; Ethylestrenol; Female; Fibrinogen; Humans; Intermittent Claudication; Male; Metformin; Middle Aged; Myocardial Infarction; Phenformin; Placebos; Vascular Diseases	1967
HB419 (glibenclamide) in the treatment of diabetes mellitus. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1969, Aug-09, Volume: 43, Issue:32 Topics: Adult; Age Factors; Aged; Biguanides; Chlorpropamide; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Female; Gallbladder Diseases; Gastrointestinal Diseases; Humans; Hypoglycemic Agents; Kidney Diseases; Liver Diseases; Male; Metformin; Middle Aged; Phenformin; Sulfonamides; Tolbutamide; Urea; Vascular Diseases	1969
[Biguanides in treatment of obesity. II. Controlled clinical research with placebos, metformin and phenformin in obesity with normal and reduced tolerance to carbohydrates]. La Clinica terapeutica, 1968, Nov-15, Volume: 47, Issue:3 Topics: Adolescent; Adult; Aged; Biguanides; Carbohydrate Metabolism; Clinical Trials as Topic; Diabetes Mellitus; Female; Humans; Male; Metformin; Middle Aged; Obesity; Phenformin; Placebos	1968
Insulin response to glucose in the presence of oral hypoglycemics. Annals of the New York Academy of Sciences, 1968, Mar-26, Volume: 148, Issue:3 Topics: Adolescent; Adult; Biguanides; Chlorpropamide; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Middle Aged; Obesity; Phenformin; Placebos	1968
Prospective study of a phenformin-like substance (moroxydine chloride) in patients with deficient vessel wall fibrinolysis. Journal of medicine, 1982, Volume: 13, Issue:5-6 Topics: Adolescent; Adult; Aged; Biguanides; Ethylestrenol; Female; Fibrinolysis; Humans; Male; Middle Aged; Morpholines; Phenformin; Pregnancy; Prospective Studies; Thrombophlebitis	1982
[The influence of clofibrate on elevated serum lactate levels in diabetic patients treated with biguanides (author's transl)]. Arzneimittel-Forschung, 1980, Volume: 30, Issue:4 Topics: Adult; Biguanides; Body Weight; Clofibrate; Diabetes Mellitus; Enzymes; Female; Humans; Hypoglycemic Agents; Lactates; Lipids; Male; Middle Aged; Phenformin; Triglycerides	1980

Other Studies

127 other study(ies) available for biguanides and phenformin

Article	Year
[Non-enzymatic fibrinolytic agents]. Annales de l'anesthesiologie francaise, 1978, Volume: 19, Issue:8 Topics: Anabolic Agents; Biguanides; Ethylestrenol; Fibrinolysis; Humans; In Vitro Techniques; Nicotinic Acids; Phenformin; Plasminogen Activators; Thrombophlebitis; Time Factors	1978
[Biguanides in the treatment of obesity]. La Clinica terapeutica, 1978, Jan-15, Volume: 84, Issue:1 Topics: Biguanides; Diabetes Mellitus; Drug Therapy, Combination; Glyburide; Humans; Insulin; Obesity; Phenformin; Sulfonylurea Compounds	1978
[Lactic acidosis (author's transl)]. Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1978, May-02, Volume: 67, Issue:18 Topics: Acidosis; Alcoholic Intoxication; Bicarbonates; Biguanides; Diabetes Complications; Fructose; Hepatic Encephalopathy; Humans; Insulin; Ketosis; Lactates; Metabolism, Inborn Errors; Parenteral Nutrition; Phenformin; Prognosis; Renal Dialysis; Sodium; Sorbitol; Xylitol	1978
[Biguanides and lactate acidosis; consequences for registration advice]. Nederlands tijdschrift voor geneeskunde, 1979, Feb-24, Volume: 123, Issue:8 Topics: Acidosis; Biguanides; Buformin; Diabetes Mellitus; Drug and Narcotic Control; Humans; Lactates; Netherlands; Phenformin	1979
[Biguanide-induced and - associated lactic acidosis: serum and tissue biguanide levels in hyperlactaemia and lactic acidosis (author's transl)]. Wiener klinische Wochenschrift, 1979, Jan-19, Volume: 91, Issue:2 Topics: Acidosis; Aged; Biguanides; Diabetes Mellitus; Glomerular Filtration Rate; Humans; Lactates; Male; Middle Aged; Phenformin; Tissue Distribution	1979
[Biguanides, rejection of treatment with buformin and fenformin, and restriction of indications for the use of metformin]. Nederlands tijdschrift voor geneeskunde, 1979, Jun-02, Volume: 123, Issue:22 Topics: Biguanides; Buformin; Drug and Narcotic Control; Humans; Hypoglycemic Agents; Metformin; Netherlands; Phenformin	1979
Inhibition of intestinal calcium transport by antidiabetic biguanides. General pharmacology, 1979, Volume: 10, Issue:3 Topics: Animals; Biguanides; Biological Transport, Active; Buformin; Calcium; Duodenum; Female; Hypoglycemic Agents; Intestinal Mucosa; Male; Oxygen Consumption; Phenformin; Rats	1979
[Effect of biguanids on the lactate metabolism. Studies in diabetics under submaximal ergometric exercise (author's transl)]. Medizinische Klinik, 1979, Jun-01, Volume: 74, Issue:22 Topics: Biguanides; Blood Glucose; Buformin; Diabetes Mellitus; Humans; Lactates; Male; Membrane Potentials; Metformin; Mitochondria; Phenformin; Physical Exertion; Pyruvates	1979
Biguanide-induced lactic acidosis in Finland. European journal of clinical pharmacology, 1979, Volume: 15, Issue:6 Topics: Acidosis; Aged; Biguanides; Finland; Humans; Hypoglycemic Agents; Lactates; Metformin; Middle Aged; Phenformin	1979
[Indications and contraindications to the diabetes mellitus therapy by biguanide derivatives in the light of the metabolic and epidemiologic studies (author's transl)]. Przeglad lekarski, 1979, Volume: 36, Issue:7 Topics: Adult; Aged; Biguanides; Buformin; Diabetes Mellitus; Humans; Metformin; Middle Aged; Phenformin	1979
Lactic acidosis: some physiological and clinical considerations. Clinical science and molecular medicine, 1977, Volume: 53, Issue:5 Topics: Acidosis; Biguanides; Biological Transport; Cell Membrane Permeability; Gluconeogenesis; Humans; Kidney; Lactates; Liver; Muscles; Phenformin	1977
[Haemodialysis in the treatment of biguanide-induced lactate acidosis (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1978, Jan-13, Volume: 103, Issue:2 Topics: Acidosis; Acute Kidney Injury; Adult; Aged; Anuria; Biguanides; Buformin; Diabetes Mellitus; Female; Humans; Lactates; Male; Middle Aged; Oliguria; Phenformin; Renal Dialysis	1978
[Biguanides and lactic acidosis]. Duodecim; laaketieteellinen aikakauskirja, 1978, Volume: 94, Issue:1 Topics: Acidosis; Biguanides; Buformin; Humans; Lactates; Metformin; Phenformin	1978
Biguanides. Diabetologia, 1978, Volume: 14, Issue:2 Topics: Biguanides; Buformin; Diabetes Mellitus; Humans; Hypoglycemic Agents; Lactates; Metformin; Phenformin	1978
The effect of short-term administration of antidiabetic biguanide derivatives on the blood lactate levels in healthy subjects. Diabetologia, 1978, Volume: 14, Issue:2 Topics: Adolescent; Adult; Biguanides; Blood Glucose; Buformin; Ethanol; Female; Fructose; Humans; Lactates; Male; Metformin; Middle Aged; Phenformin; Physical Exertion	1978
Blood lactate and pyruvate levels in diabetic patients treated with biguanides with and without sulphonylureas. Diabetologia, 1978, Volume: 14, Issue:2 Topics: Adolescent; Adult; Aged; Biguanides; Diabetes Mellitus; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Lactates; Male; Metformin; Middle Aged; Phenformin; Pyruvates; Sulfonylurea Compounds	1978
An experimental model of phenformin-induced lactic acidosis in rats. Diabetologia, 1978, Volume: 14, Issue:4 Topics: Acidosis; Animals; Biguanides; Disease Models, Animal; Lactates; Male; Nephrectomy; Phenformin; Rats	1978
Biguanides and lactic acidosis. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, Mar-04, Volume: 53, Issue:9 Topics: Acidosis; Biguanides; Humans; Lactates; Phenformin	1978
[Comparison of the effects of phenformin, buformin and metformin on blood lactate level]. Polskie Archiwum Medycyny Wewnetrznej, 1978, Volume: 59, Issue:3 Topics: Biguanides; Buformin; Female; Humans; Lactates; Male; Metformin; Phenformin	1978
[Biguanides]. Deutsche medizinische Wochenschrift (1946), 1978, Sep-08, Volume: 103, Issue:36 Topics: Acidosis; Biguanides; Buformin; Humans; Metformin; Phenformin	1978
Comparison of McN-3495 [N-(1-methyl-2-pyrrolidinylidene)-N'-phenyl-1-pyrrolidinecarboximidamide], a new, orally effective, hypoglycemic agent, with the biguanides. Diabetes, 1978, Volume: 27, Issue:8 Topics: Animals; Biguanides; Biological Transport, Active; Blood Glucose; Buformin; Diabetes Mellitus, Experimental; Dogs; Female; Glucose; Glucose Tolerance Test; Hypoglycemic Agents; Intestinal Absorption; Lactates; Male; Phenformin; Rats	1978
[Biguanides: reasons for withdrawal of drugs and remaining indications]. Acta medica Austriaca, 1978, Volume: 5, Issue:3 Topics: Acidosis; Austria; Biguanides; Buformin; Diabetes Mellitus; Humans; Lactates; Legislation, Drug; Metformin; Obesity; Phenformin	1978
[Blood lactate and biguanide therapy: comparison between phenformin, metformin and buformin in 408 senile diabetics]. Acta medica Austriaca, 1978, Volume: 5, Issue:3 Topics: Aged; Biguanides; Buformin; Diabetes Mellitus; Female; Humans; Lactates; Male; Metformin; Phenformin	1978
[Effect of biguanide therapy on lactate metabolism during graded submaximal ergometric testing]. Acta medica Austriaca, 1978, Volume: 5, Issue:3 Topics: Biguanides; Buformin; Diabetes Mellitus; Humans; Lactates; Metformin; Phenformin; Physical Exertion	1978
[Treatment of diabetes mellitus with oral antidiabetics]. Schweizerische medizinische Wochenschrift, 1976, Nov-27, Volume: 106, Issue:48 Topics: Administration, Oral; Biguanides; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Humans; Hypoglycemic Agents; Insulin; Phenformin; Prospective Studies	1976
Phenformin, tetracycline and lactic acidosis. Annals of internal medicine, 1977, Volume: 86, Issue:1 Topics: Acidosis; Biguanides; Diabetes Mellitus; Drug Interactions; Humans; Phenformin; Tetracycline	1977
[Lactacidosis in diabetic patients treated with biguanides]. Die Medizinische Welt, 1977, Feb-25, Volume: 28, Issue:8 Topics: Acidosis; Aged; Biguanides; Diabetes Mellitus; Female; Humans; Lactates; Male; Middle Aged; Phenformin	1977
[Lactic acidosis after administration of guanidine derivatives (buformine, phenformine) (author's transl)]. Medizinische Klinik, 1977, Apr-22, Volume: 72, Issue:16 Topics: Acidosis; Aged; Bicarbonates; Biguanides; Buformin; Diabetes Mellitus; Female; Glomerular Filtration Rate; Humans; Lactates; Male; Middle Aged; Phenformin; Renal Dialysis; Sodium	1977
Alteration of bile acid metabolism and vitamin-B12-absorption in diabetics on biguanides. Diabetologia, 1977, Volume: 13, Issue:3 Topics: Biguanides; Buformin; Carbon Dioxide; Cholic Acids; Diabetes Mellitus; Doxycycline; Feces; Female; Glycocholic Acid; Humans; Male; Metformin; Middle Aged; Phenformin; Vitamin B 12	1977
[Lactic acidosis and biguanides: present state of the question in France]. Journees annuelles de diabetologie de l'Hotel-Dieu, 1977 Topics: Adult; Aged; Biguanides; Diabetes Mellitus; Female; France; Humans; Lactates; Male; Metformin; Middle Aged; Phenformin	1977
Editorial: Diabetic hearts and biguanides-a reply. Canadian Medical Association journal, 1976, Sep-04, Volume: 115, Issue:5 Topics: Biguanides; Diabetes Mellitus; Heart Diseases; Humans; Phenformin	1976
Editorial: Diabetic hearts and biguanides-a counter-reply. Canadian Medical Association journal, 1976, Sep-04, Volume: 115, Issue:5 Topics: Biguanides; Diabetes Mellitus; Heart Diseases; Humans; Phenformin	1976
[Lactic acidosis and biguanid therapy (author's transl)]. Medizinische Klinik, 1976, Sep-03, Volume: 71, Issue:36 Topics: Acidosis; Aged; Anti-Bacterial Agents; Bicarbonates; Biguanides; Buffers; Buformin; Diabetes Mellitus; Female; Glucose; Humans; Iatrogenic Disease; Insulin; Lactates; Male; Middle Aged; Phenformin; Renal Dialysis; Urinary Tract Infections	1976
Intestinal absorption characteristics of buformin and phenformin in rats. Chemical & pharmaceutical bulletin, 1976, Volume: 24, Issue:7 Topics: Animals; Biguanides; Buformin; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Male; Phenformin; Rats	1976
The biguanides: action and clinical indications. Australian family physician, 1976, Volume: 5, Issue:7 Topics: Biguanides; Diabetes Mellitus; Humans; Hyperglycemia; Metformin; Phenformin	1976
Oral hypoglycaemic agents--dangers and contraindications. The Medical journal of Australia, 1976, Oct-16, Volume: 2, Issue:16 Topics: Aged; Biguanides; Cardiovascular Diseases; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Lactates; Phenformin; Pregnancy; Sulfonylurea Compounds; Tolbutamide	1976
[The importance of lactate acidosis as a side effect of biguanide therapy]. Fortschritte der Medizin, 1976, Dec-16, Volume: 94, Issue:35-36 Topics: Acidosis; Biguanides; Buformin; Diabetes Mellitus; Drug Therapy, Combination; Ethanol; Humans; Kidney; Lactates; Liver; Metformin; Peritoneal Dialysis; Phenformin	1976
[10 cases of lactic acidosis during biguanide therapy (buformin and phenformin)]. Schweizerische medizinische Wochenschrift, 1976, Dec-11, Volume: 106, Issue:50 Topics: Acidosis; Biguanides; Buformin; Diabetes Mellitus; Glucagon; Humans; Lactates; Liver; Metformin; Phenformin; Shock, Cardiogenic	1976
Simple elcetron capture gas chromatographic method for the determination of oral hypoglycemic biguanidis in biological fluids. Analytical chemistry, 1975, Volume: 47, Issue:3 Topics: Biguanides; Buformin; Chromatography, Gas; Humans; Metformin; Phenformin	1975
[Correction of endocrine-metabolic disorders in oncologic patients. The effect of biguanides (phenformin and adebita), miskleron and diphenin]. Voprosy onkologii, 1975, Volume: 21, Issue:11 Topics: Adrenal Cortex Hormones; Aged; Biguanides; Blood Glucose; Body Weight; Breast Neoplasms; Buformin; Cholesterol; Clofibrate; Colonic Neoplasms; Endocrine System Diseases; Fatty Acids; Female; Growth Hormone; Humans; Insulin; Lipoproteins; Lung Neoplasms; Middle Aged; Neoplasms; Phenformin; Phenytoin; Phospholipids; Triglycerides; Uric Acid; Uterine Neoplasms	1975
Characterization of phenformin and metabolites in plasma. Diabete & metabolisme, 1975, Volume: 1, Issue:4 Topics: Animals; Biguanides; Chromatography, Thin Layer; Colorimetry; Humans; Lactates; Phenformin; Rats	1975
[Lactic acidosis induced by biguanides]. La Nouvelle presse medicale, 1976, Jan-31, Volume: 5, Issue:5 Topics: Acidosis; Biguanides; Diabetes Mellitus; Gluconeogenesis; Humans; Lactates; Phenformin	1976
Effect of bed time intermediate acting insulin in NIDDM subjects refractory to a combination of sulphonylureas and biguanides. The Journal of the Association of Physicians of India, 1992, Volume: 40, Issue:10 Topics: Biguanides; Blood Glucose; Chlorpropamide; Diabetes Mellitus, Type 2; Drug Combinations; Female; Glipizide; Glyburide; Glycated Hemoglobin; Humans; Injections, Subcutaneous; Insulin, Long-Acting; Lipids; Male; Metformin; Middle Aged; Phenformin; Sulfonylurea Compounds; Time Factors	1992
Biguanide related lactic acidosis: incidence and risk factors. Archives of medical research, 1992,Spring, Volume: 23, Issue:1 Topics: Acidosis, Lactic; Adolescent; Adult; Aged; Aged, 80 and over; Biguanides; Contraindications; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Emergencies; Female; Humans; Incidence; Male; Metformin; Mexico; Middle Aged; Odds Ratio; Phenformin; Prospective Studies; Retrospective Studies; Risk Factors; Sulfonylurea Compounds	1992
Effects of insulin, biguanide antihyperglycaemic agents and beta-adrenergic agonists on pathways of myocardial proteolysis. The Biochemical journal, 1990, Mar-15, Volume: 266, Issue:3 Topics: Adrenergic beta-Agonists; Animals; Biguanides; Chloroquine; Drug Therapy, Combination; In Vitro Techniques; Insulin; Isoproterenol; Lysosomes; Myocardial Contraction; Myocardium; Phenformin; Protease Inhibitors; Protein Denaturation; Rats	1990
Carbohydrate biguanides as potential hypoglycemic agents. Journal of medicinal chemistry, 1989, Volume: 32, Issue:9 Topics: Administration, Oral; Animals; Biguanides; Glucose Tolerance Test; Hypoglycemic Agents; Male; Mass Spectrometry; Metformin; Monosaccharides; Phenformin; Rats; Rats, Inbred Strains; Structure-Activity Relationship	1989
[Alteration of blood lactic acid levels in biguanide therapy in diabetics]. Sichuan yi xue yuan xue bao = Acta Academiae Medicinae Sichuan, 1985, Volume: 16, Issue:2 Topics: Biguanides; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Humans; Lactates; Lactic Acid; Metformin; Middle Aged; Phenformin	1985
Pharmacological fibrinolysis after surgical operations. Lancet (London, England), 1971, Apr-17, Volume: 1, Issue:7703 Topics: Biguanides; Ethylestrenol; Fibrinolytic Agents; Humans; Phenformin; Plasminogen; Postoperative Complications; Thromboembolism; Thrombophlebitis	1971
Editorial: Oral therapy in diabetes mellitus. Southern medical journal, 1974, Volume: 67, Issue:6 Topics: Acetohexamide; Biguanides; Chlorpropamide; Diabetes Mellitus; Diabetic Ketoacidosis; Diet Therapy; Humans; Hypoglycemia; Hypoglycemic Agents; Lactates; Phenformin; Placebos; Pyruvates; Sulfonylurea Compounds; Tolazamide; Tolbutamide; Typhoid Fever	1974
[The glibenclamide-phenformin combination in the therapy of diabetes mellitus]. Minerva medica, 1974, Aug-29, Volume: 65, Issue:59 Topics: Adult; Aged; Biguanides; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Drug Combinations; Drug Evaluation; Drug Synergism; Female; Glyburide; Humans; Insulin; Male; Middle Aged; Phenformin; Tolbutamide	1974
Effects of biguanides on fatty acid and glucose oxidation in muscle. Pharmacological research communications, 1974, Volume: 6, Issue:3 Topics: Animals; Biguanides; Carbon Dioxide; Carbon Radioisotopes; Diaphragm; Fatty Acids; Glucose; In Vitro Techniques; Male; Muscles; Oxidation-Reduction; Oxygen Consumption; Palmitic Acids; Phenformin; Rats	1974
Calcium-like action of phenethylbiguanide and related compounds: inhibition of pyruvate kinase. Proceedings of the National Academy of Sciences of the United States of America, 1972, Volume: 69, Issue:7 Topics: Animals; Biguanides; Binding Sites; Calcium; Calcium Isotopes; Creatine Kinase; Enzyme Activation; Hexokinase; Kinetics; Lithium; Manganese; Muscles; Phenformin; Phosphoglucomutase; Phosphoglycerate Kinase; Protein Binding; Pyruvate Kinase; Quaternary Ammonium Compounds; Rabbits; Radioisotopes; Structure-Activity Relationship; Tritium	1972
The effect of biguanides on secretion and biosynthesis of insulin in isolated pancreatic islets of rats. Diabetologia, 1972, Volume: 8, Issue:6 Topics: Animals; Biguanides; Drug Interactions; Glucose; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Metformin; Oxygen Consumption; Phenformin; Rats; Rats, Inbred Strains; Tritium	1972
[Animal experimental studies on the mode of action of biguanides. 1. Studies with hypoglycemia-inducing doses of biguanide]. Arzneimittel-Forschung, 1972, Volume: 22, Issue:7 Topics: Animals; Biguanides; Blood Glucose; Carbon Isotopes; Diaphragm; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Female; Germ-Free Life; Gluconeogenesis; Glucose; Guinea Pigs; Hypoglycemia; Insulin; Insulin Secretion; Liver; Male; Metformin; Oxygen Consumption; Phenformin; Rats	1972
[Animal experimental studies on the mode of action of biguanides. 1. Studies on non hypoglycemically acting biguanide]. Arzneimittel-Forschung, 1972, Volume: 22, Issue:9 Topics: Animals; Biguanides; Butanes; Carbon Dioxide; Carbon Isotopes; Diabetes Mellitus; Diaphragm; Fatty Acids, Nonesterified; Gluconeogenesis; Glucose; Glycogen; Guinea Pigs; Hexokinase; Insulin; Lactates; Liver; Metformin; Muscles; Phenformin; Pyruvates; Rats	1972
[Influenza epidemic in 1971 in diabetics treated with 1-butyl-biguanidine hydrochloride (Silubin retard) and 1-phenylethyl-biguanidine hydrochloride (Phenformin)]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1973, Nov-12, Volume: 28, Issue:46 Topics: Biguanides; Butanes; Diabetes Complications; Diabetes Mellitus; Disease Outbreaks; Humans; Influenza, Human; Phenformin; Poland	1973
[Demonstration of the mechanism of action of biguanides (author's transl)]. Acta diabetologica latina, 1973, Volume: 10, Issue:6 Topics: Animals; Biguanides; Fatty Acids; Glucose; Liver; Male; Metformin; Muscles; Oxidation-Reduction; Palmitic Acids; Phenformin; Rats	1973
[Biguanide therapy of primary hyperlipoproteinemias type IIb, 3 and IV as monotherapy and combined with clofibrate]. Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1973, Volume: 79 Topics: Adult; Aged; Biguanides; Clofibrate; Drug Combinations; Humans; Hyperlipidemias; Middle Aged; Phenformin	1973
[A phosphorylated biguanide: benfosformin (JAV 852). I. Hypoglycemic and antidiabetic properties]. Arzneimittel-Forschung, 1973, Volume: 23, Issue:11 Topics: Animals; Benzyl Compounds; Biguanides; Blood Glucose; Diabetes Mellitus, Experimental; Hyperglycemia; Hypoglycemic Agents; Lactates; Lethal Dose 50; Male; Mice; Organophosphorus Compounds; Phenformin; Rats; Time Factors	1973
Fibrinolytic studies with biguanide derivatives. Annals of the New York Academy of Sciences, 1968, Mar-26, Volume: 148, Issue:3 Topics: Animals; Biguanides; Blood Glucose; Cats; Dogs; Fibrinolysis; Fibrinolytic Agents; Haplorhini; Insulin; Phenformin; Serum Globulins; Thrombelastography; Thromboembolism	1968
Clinical experiences in oral antidiabetic therapy with sulphonylureas and biguanides. Australian and New Zealand journal of medicine, 1971, Volume: 1 Topics: Aged; Biguanides; Blood Glucose; Diabetes Mellitus; Glyburide; Humans; Insulin; Middle Aged; Phenformin; Sulfonylurea Compounds; Tolbutamide	1971
Gas chromatographic behavior of buformin hydrochloride, phenformin hydrochloride and phenylbiguanide. The pyrolytic formation of substituted 2,4,6-triamino-1,3,5-triazines from biguanides. Journal of chromatography, 1972, Sep-06, Volume: 71, Issue:2 Topics: Amines; Benzene Derivatives; Biguanides; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Thin Layer; Hot Temperature; Hypoglycemic Agents; Infrared Rays; Magnetic Resonance Spectroscopy; Mass Spectrometry; Phenformin; Spectrum Analysis; Triazines; Ultraviolet Rays	1972
Diabetes mellitus--refractory obesity. British medical journal, 1972, Jul-15, Volume: 3, Issue:5819 Topics: Biguanides; Diabetes Mellitus; Diet Therapy; Female; Fetal Death; Glucose Tolerance Test; Glycosuria; Humans; Insulin; Metformin; Middle Aged; Obesity; Phenformin; Pregnancy; Pregnancy in Diabetics; Sulfonylurea Compounds	1972
Application of ion-pair methods to drug extraction from biological fluids. I. Quantitative determination of biguanides in urine. Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:9 Topics: Animals; Biguanides; Chemistry, Pharmaceutical; Coloring Agents; Hydrogen-Ion Concentration; Ions; Mathematics; Metformin; Phenformin; Spectrophotometry; Spectrum Analysis; Ultraviolet Rays	1972
Application of ion-pair methods to drug extraction from biological fluids. II. Quantitative determination of biguanides in biological fluids and comparison of protein binding estimates. Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:9 Topics: Animals; Biguanides; Chemistry, Pharmaceutical; Cresols; Dialysis; Dogs; Erythrocytes; Filtration; Humans; Hydrogen-Ion Concentration; Ions; Mathematics; Metformin; Phenformin; Protein Binding; Solvents; Spectrophotometry	1972
[Physiological and pharmacological aspects of fibrinolysis]. La Clinica terapeutica, 1971, May-15, Volume: 57, Issue:3 Topics: Adrenal Cortex Hormones; Anabolic Agents; Arteriosclerosis Obliterans; Biguanides; Blood Coagulation Tests; Blood Platelets; Clofibrate; Coronary Disease; Diabetes Mellitus; Ethylestrenol; Fibrinolysis; Humans; Insulin; Metformin; Myocardial Infarction; Phenformin; Sulfonylurea Compounds; Testosterone; Thrombosis	1971
[Comparative activity of some biguanides, sulfonylureas and their combinations on blood sugar and lactic acid in the guinea pig. II]. Bollettino chimico farmaceutico, 1971, Volume: 110, Issue:4 Topics: Amantadine; Animals; Biguanides; Blood Glucose; Chlorpropamide; Guinea Pigs; Lactates; Metformin; Phenformin; Sulfonylurea Compounds; Tolbutamide	1971
[Use of dibotine in treating diabetes mellitus]. Sovetskaia meditsina, 1971, Volume: 34, Issue:8 Topics: Adult; Animals; Biguanides; Diabetes Mellitus; Female; Humans; Male; Middle Aged; Phenformin; Sulfonylurea Compounds	1971
[Effect of biguanide derivatives on blood lactic acid level in diabetics]. Polskie Archiwum Medycyny Wewnetrznej, 1971, Volume: 47, Issue:6 Topics: Adult; Aged; Biguanides; Diabetes Mellitus; Humans; Lactates; Metformin; Middle Aged; Phenformin	1971
Biguanides. Mode of action and role in the up-to-date treatment of diabetes mellitus. Therapia Hungarica (English edition), 1971, Volume: 19, Issue:2 Topics: Acidosis; Administration, Oral; Biguanides; Delayed-Action Preparations; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Insulin; Kidney Diseases; Lactates; Phenformin; Sulfonylurea Compounds	1971
The fate of biguanides in man. Annals of the New York Academy of Sciences, 1968, Mar-26, Volume: 148, Issue:3 Topics: Biguanides; Carbon Isotopes; Chemistry, Clinical; Chromatography, Ion Exchange; Humans; Hypoglycemic Agents; Kidney; Kinetics; Phenformin; Spectrophotometry; Tritium; Ultraviolet Rays	1968
Fibrinolytic effect of biguanides. Annals of the New York Academy of Sciences, 1968, Mar-26, Volume: 148, Issue:3 Topics: Adult; Aged; Angina Pectoris; Arteriosclerosis Obliterans; Biguanides; Chlorpropamide; Coronary Disease; Ethylestrenol; Female; Fibrinolysis; Fibrinolytic Agents; Humans; Male; Metformin; Methenolone; Middle Aged; Phenformin; Tolbutamide	1968
[Effect of the administration of phenyl-ethyl-biguanide on tolerance to oral administration of glucose in chronic uremia]. Bollettino della Societa italiana di biologia sperimentale, 1969, Jan-15, Volume: 45, Issue:1 Topics: Biguanides; Chronic Disease; Glucose; Glucose Tolerance Test; Humans; Insulin; Phenformin; Uremia	1969
Rat liver glycogen-lowering activity of fed creatine--a retraction. The Journal of nutrition, 1969, Volume: 99, Issue:4 Topics: Animals; Biguanides; Creatine; Crystallization; Depression, Chemical; Gluconeogenesis; Guanidines; Hypoglycemic Agents; Injections, Intraperitoneal; Liver Glycogen; Male; Metformin; Phenformin; Rats; Time Factors	1969
Studies on the mechanism of weight reduction by phenformin. Postgraduate medical journal, 1969, Volume: 45 Topics: Biguanides; Diabetes Mellitus; Female; Humans; Metformin; Obesity; Phenformin	1969
Pharmacological fibrinolysis in occlusive vascular disease and its relation to diabetes mellitus. Postgraduate medical journal, 1969, Volume: 45 Topics: Biguanides; Coronary Disease; Diabetes Complications; Diabetes Mellitus; Drug Synergism; Ethylestrenol; Female; Fibrinolysis; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Nandrolone; Phenformin; Platelet Adhesiveness; Testosterone	1969
[Impairment of intestinal glucose absorption by biguanide derivatives]. Acta diabetologica latina, 1969, Volume: 6 Suppl 1 Topics: Age Factors; Animals; Biguanides; Blood Glucose; Diabetes Mellitus; Dogs; Glucose; Glucose Tolerance Test; Humans; Infusions, Parenteral; Intestinal Absorption; Intestine, Small; Perfusion; Phenformin	1969
On the inhibition of gluconeogenesis by biguanides in the perfused guinea pig liver. Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1970, Volume: 351, Issue:3 Topics: Alanine; Animals; Biguanides; Citric Acid Cycle; Depression, Chemical; Fructose; Gluconeogenesis; Glyceric Acids; Guinea Pigs; In Vitro Techniques; Lactates; Liver; Perfusion; Phenformin; Phosphoric Acids; Pyruvates; Trioses	1970
[The place of biguanides in the treatment of diabetes]. Therapeutique (La Semaine des hopitaux), 1970, Volume: 46, Issue:2 Topics: Biguanides; Diabetes Mellitus; Drug Synergism; Humans; Hypoglycemic Agents; Insulin; Metformin; Phenformin	1970
Weight change with orally administered "antidiabetic" drugs. JAMA, 1970, Sep-07, Volume: 213, Issue:10 Topics: Adipose Tissue; Administration, Oral; Animals; Biguanides; Body Weight; Diabetes Mellitus; Diet; Female; Humans; Hypoglycemic Agents; Insulin; Intestinal Absorption; Lipid Metabolism; Mice; Obesity; Phenformin	1970
Long term observations with oral hypoglycemic drugs: sulphonylureas, biguanides and their combination. Indian journal of medical sciences, 1970, Volume: 24, Issue:7 Topics: Administration, Oral; Adult; Age Factors; Aged; Biguanides; Carbutamide; Chlorpropamide; Diabetes Mellitus; Diet; Drug Combinations; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenformin; Sulfonylurea Compounds; Time Factors; Tolbutamide	1970
[Hypoglycemia after treatment with Glibenclamid (Euglucon 5)]. Munchener medizinische Wochenschrift (1950), 1970, Nov-27, Volume: 112, Issue:48 Topics: Aged; Biguanides; Cyclohexanes; Diabetes Mellitus; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Phenformin; Sulfones; Urea	1970
[Resorption and biological degradation of N1-beta-phenethyl-biguanide (phenformin)]. Diabetologia, 1967, Volume: 3, Issue:4 Topics: Animals; Biguanides; Chromatography, Paper; Glucuronates; Guinea Pigs; Humans; Intestinal Absorption; Mice; Phenformin; Rabbits; Rats; Species Specificity; Tritium	1967
Effects of 1-beta-phenethylbiguanide (DBI) on the metabolism of the isolated rat fat pad. Diabetologia, 1967, Volume: 3, Issue:4 Topics: Adipose Tissue; Animals; Biguanides; Carbon Dioxide; Carbon Isotopes; Culture Techniques; Epididymis; Glucose; Glycogen; Insulin Antagonists; Lactates; Male; Oxygen Consumption; Phenformin; Pyruvates; Rats	1967
Metabolic effects of the biguanides and possible mechanism of action. Diabetes, 1968, Volume: 17, Issue:2 Topics: Adipose Tissue; Animals; Biguanides; Biological Transport; Columbidae; Gluconeogenesis; Glucose; Guinea Pigs; Hypoglycemia; Liver; Oxidation-Reduction; Oxidative Phosphorylation; Phenformin; Pyruvates; Rats	1968
Effects of guanidine derivatives on mitochondrial function. II. Reversal of guanidine-derivative inhibiton by free fatty acids. The Journal of clinical investigation, 1968, Volume: 47, Issue:10 Topics: Animals; Biguanides; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography; Depression, Chemical; Drug Synergism; Fatty Acids; Fatty Acids, Nonesterified; Guanidines; Guinea Pigs; Heart; Mitochondria; Myocardium; Nitrophenols; Oxygen Consumption; Phenformin; Protein Binding; Proteins; Pyruvates; Serum Albumin; Serum Albumin, Bovine; Stearic Acids; Tritium	1968
[Clinical pharmacology of oral hypoglycemic drugs]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1968, Sep-19, Volume: 23, Issue:34 Topics: Biguanides; Humans; Hypoglycemic Agents; Metformin; Phenformin	1968
Oral hypoglycemic agents. Pediatrics, 1969, Volume: 43, Issue:4 Topics: Biguanides; Child; Diabetes Mellitus, Type 1; Humans; Hypoglycemic Agents; Insulin; Phenformin; Prediabetic State	1969
[On the clinical use of biguanides]. Arzneimittel-Forschung, 1969, Volume: 19, Issue:4 Topics: Aged; Biguanides; Blood Glucose; Body Weight; Cholesterol; Depression, Chemical; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Fatty Liver; Humans; Hypoglycemic Agents; Insulin; Liver Glycogen; Metformin; Phenformin; Stimulation, Chemical	1969
[Therapeutic possibilities in diabetes mellitus with biguanides. Clinical experiences in 122 diabetics with dimethylbiguanide(Glucophage)]. Schweizerische medizinische Wochenschrift, 1966, Oct-08, Volume: 96, Issue:40 Topics: Adolescent; Adult; Biguanides; Body Weight; Chemical Phenomena; Chemistry; Diabetes Mellitus; Diet, Diabetic; Female; Glucose Tolerance Test; Humans; Insulin; Male; Metformin; Phenformin	1966
Effects of biguanides on short-circuit current in frog skin. The American journal of physiology, 1984, Volume: 247, Issue:2 Pt 2 Topics: Amiloride; Animals; Biguanides; Buformin; Galvanic Skin Response; Metformin; Mucous Membrane; Phenformin; Rana pipiens; Serous Membrane; Skin; Sodium; Time Factors	1984
Antidiabetic behavior of biguanides. Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:5 Topics: Biguanides; Chemical Phenomena; Chemistry, Physical; Hydrogen-Ion Concentration; Hypoglycemic Agents; Insulin; Phenformin; Polarography	1983
Failure of the biguanide moroxydine chloride to stimulate plasma fibrinolytic activity. Acta medica Scandinavica, 1984, Volume: 215, Issue:3 Topics: Adult; Aged; Biguanides; Drug Evaluation; Female; Fibrinolysis; Humans; Male; Middle Aged; Morpholines; Phenformin; Recurrence; Tablets; Thrombophlebitis	1984
Malabsorption of vitamin B12 and intrinsic factor secretion during biguanide therapy. Diabetologia, 1983, Volume: 24, Issue:1 Topics: Adult; Aged; Biguanides; Diabetes Mellitus; Female; Humans; Intrinsic Factor; Malabsorption Syndromes; Male; Metformin; Middle Aged; Phenformin; Vitamin B 12	1983
Comparison of the in vitro effect of biguanides and sulfonylureas on insulin binding of its receptors in target cells. The Journal of clinical endocrinology and metabolism, 1982, Volume: 54, Issue:1 Topics: Animals; Biguanides; Breast Neoplasms; Cell Line; Female; Fibroblasts; Humans; Insulin; Liver Neoplasms, Experimental; Lymphocytes; Metformin; Phenformin; Rats; Receptor, Insulin; Sulfonylurea Compounds	1982
[Biguanides in the treatment of diabetes]. Duodecim; laaketieteellinen aikakauskirja, 1980, Volume: 96, Issue:7 Topics: Biguanides; Diabetes Mellitus; Humans; Metformin; Phenformin	1980
Anti-diabetic biguanides inhibit hormone-induced intracellular Ca2+ concentration oscillations in rat hepatocytes. The Biochemical journal, 1994, Dec-01, Volume: 304 ( Pt 2) Topics: Animals; Biguanides; Bucladesine; Calcium; Chlorides; Colforsin; Cyclic AMP; Glucagon; Inositol 1,4,5-Trisphosphate; Insulin; Liver; Male; Manganese Compounds; Metformin; Phenformin; Phenylephrine; Rats; Rats, Wistar; Second Messenger Systems	1994
Vanadyl-biguanide complexes as potential synergistic insulin mimics. Journal of inorganic biochemistry, 1999, Sep-30, Volume: 76, Issue:3-4 Topics: Animals; Biguanides; Blood Glucose; Diabetes Mellitus, Experimental; Drug Synergism; Humans; Hypoglycemic Agents; In Vitro Techniques; Insulin; Male; Metformin; Phenformin; Rats; Rats, Wistar; Vanadates	1999
Enhanced secretion of glucagon-like peptide 1 by biguanide compounds. Biochemical and biophysical research communications, 2002, Nov-15, Volume: 298, Issue:5 Topics: Animals; Biguanides; Buformin; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Hypoglycemic Agents; In Vitro Techniques; Male; Metformin; Peptide Fragments; Phenformin; Protease Inhibitors; Protein Precursors; Pyrroles; Rats; Rats, Inbred F344; Valine	2002
[Studies on the metabolic effects of hypoglycemic biguanides in various animal species]. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1963, Volume: 244 Topics: Animals; Biguanides; Hypoglycemic Agents; Phenformin	1963
[Oral treatment of diabetes mellitus. Clinical experience of Metformin or Phenformin alone and combined treatment with these biguanides and P-607]. Naika hokan. Japanese archives of internal medicine, 1962, Volume: 9 Topics: Administration, Oral; Biguanides; Chlorpropamide; Diabetes Mellitus; Humans; Metformin; Phenformin	1962
Antifertility effects of biguanides. Antibiotics & chemotherapy (Northfield, Ill.), 1962, Volume: 12 Topics: Antimalarials; Biguanides; Fertility; Guanidine; Guanidines; Humans; Phenformin; Proguanil	1962
[Delayed-action phenyl-ethyl-biguanide and treatment of diabetes]. Minerva medica, 1963, Apr-14, Volume: 54 Topics: Biguanides; Delayed-Action Preparations; Diabetes Mellitus; Humans; Phenformin	1963
[CHANGES IN THE POTENCY OF CHLORPROMAZINE AND HYPOGLYCEMIC BIGUANIDES BY COMBINED ADMINISTRATION]. Medicina experimentalis : International journal of experimental medicine, 1963, Volume: 8 Topics: Animals; Biguanides; Blood Glucose; Chlorpromazine; Guinea Pigs; Humans; Hypoglycemic Agents; Manipulation, Osteopathic; Pharmacology; Phenformin; Research	1963
[ON THE COMBINATION OF SULFONYLUREA AND BIGUANIDE IN SMALL DOSES IN THE THERAPY OF DIABETES MELLITUS]. Minerva medica, 1963, Aug-11, Volume: 54 Topics: Biguanides; Diabetes Mellitus; Humans; Hypoglycemic Agents; Phenformin	1963
[OLIGOMYCIN-LIKE EFFECTS OF BIGUANIDES]. Biochemische Zeitschrift, 1963, Sep-19, Volume: 339 Topics: Anti-Bacterial Agents; Antifungal Agents; Biguanides; Cytochromes; Liver; Metabolism; Mitochondria; Oligomycins; Oxidation-Reduction; Phenformin; Rats; Research; Succinates	1963
[TREATMENT OF DIABETES MELLITUS WITH BIGUANIDES]. Terapevticheskii arkhiv, 1963, Volume: 35 Topics: Adolescent; Biguanides; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Humans; Insulin; Phenformin	1963
[CLINICAL EVALUATION OF AN ORAL ANTIDIABETIC CONSISTING OF THE ASSOCIATION OF A SULFONYLUREA AND A BIGUANIDE]. Minerva medica, 1964, Apr-25, Volume: 55 Topics: Adolescent; Biguanides; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Geriatrics; Humans; Hypoglycemic Agents; Phenformin	1964
[ROLE OF BIGUANIDES IN THE TREATMENT OF DIABETES]. Turk Tip Cemiyeti mecmuasi, 1964, Volume: 30 Topics: Biguanides; Diabetes Mellitus; Humans; Metformin; Phenformin; Toxicology	1964
[CHLORPROPAMIDE AND PHENETHYLBIGUANIDE ASSOCIATED WITH INSULIN THERAPY IN SOME CASES OF INSULIN RESISTANCE]. Gazzetta medica italiana, 1965, Volume: 124 Topics: Antimalarials; Biguanides; Chlorpropamide; Diabetes Mellitus; Guanidine; Guanidines; Humans; Insulin; Insulin Resistance; Phenformin	1965
Methyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic beta-cells through restoration of mitochondrial electron transfer. British journal of pharmacology, 2007, Volume: 150, Issue:8 Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Biguanides; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Electron Transport; Electron Transport Complex I; Electron Transport Complex II; Enzyme Activation; Glucose; Hypoglycemic Agents; Insulin-Secreting Cells; Metformin; Mice; Mitochondria; Multienzyme Complexes; NADP; Oxidation-Reduction; Phenformin; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Succinates; Tetrazolium Salts; Thiazoles; Time Factors	2007
Comparison of the kinetic characteristics of inhibitory effects exerted by biguanides and H2-blockers on human and rat organic cation transporter-mediated transport: Insight into the development of drug candidates. Xenobiotica; the fate of foreign compounds in biological systems, 2007, Volume: 37, Issue:6 Topics: 1-Methyl-4-phenylpyridinium; Animals; Biguanides; Cell Line; Cimetidine; Drug Design; Famotidine; Histamine H2 Antagonists; Humans; Ion Transport; Kinetics; Metformin; Organic Cation Transport Proteins; Phenformin; Ranitidine; Rats; Tetraethylammonium	2007
Liver uptake of biguanides in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2011, Volume: 65, Issue:6 Topics: Animals; Biguanides; Biological Transport, Active; Biotransformation; Cells, Cultured; Hepatocytes; Hypoglycemic Agents; Liver; Male; Metformin; Phenformin; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Tissue Distribution	2011
Relevance of the OCT1 transporter to the antineoplastic effect of biguanides. Biochemical and biophysical research communications, 2011, Nov-04, Volume: 414, Issue:4 Topics: Adenylate Kinase; Antineoplastic Agents; Biguanides; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Humans; Metformin; Organic Cation Transporter 1; Ovarian Neoplasms; Phenformin; RNA, Small Interfering	2011
Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP. Nature, 2013, Feb-14, Volume: 494, Issue:7436 Topics: Adenylyl Cyclases; AMP-Activated Protein Kinases; Animals; Biguanides; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Type 2; Enzyme Activation; Glucagon; Glucose; Hepatocytes; Hypoglycemic Agents; Liver; Metformin; Mice; Phenformin; Phosphorylation; Signal Transduction	2013
Biguanides inhibit complex I, II and IV of rat liver mitochondria and modify their functional properties. Physiological research, 2014, Volume: 63, Issue:1 Topics: Animals; Biguanides; Dose-Response Relationship, Drug; Electron Transport Complex I; Electron Transport Complex II; Electron Transport Complex IV; Enzyme Inhibitors; Male; Metformin; Mitochondria, Liver; Phenformin; Rats; Rats, Wistar	2014
Use of biguanides and the risk of colorectal cancer: a register-based cohort study. Current drug safety, 2013, Volume: 8, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biguanides; Cohort Studies; Colorectal Neoplasms; Comorbidity; Denmark; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Netherlands; Phenformin; Population; Registries; Risk Factors; Young Adult	2013
Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides. Nature, 2014, Apr-03, Volume: 508, Issue:7494 Topics: Adenosine Triphosphate; Animals; Biguanides; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Culture Media; DNA, Mitochondrial; Electron Transport Complex I; Glucose; Humans; Hypoglycemic Agents; Male; Mice; Mitochondria; Molecular Typing; Mutation; Neoplasm Transplantation; Neoplasms; Oxidative Phosphorylation; Phenformin; RNA Interference; Saccharomyces cerevisiae Proteins; Xenograft Model Antitumor Assays	2014
Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells. Proceedings of the National Academy of Sciences of the United States of America, 2014, Jul-22, Volume: 111, Issue:29 Topics: Aminoimidazole Carboxamide; Biguanides; Cell Line, Transformed; Cell Line, Tumor; Citric Acid Cycle; Endoplasmic Reticulum; Folic Acid; Glycerophosphates; Glycolysis; Humans; Lactates; Metabolome; Metformin; Neoplastic Stem Cells; Nucleotides; Phenformin; Ribonucleotides; src-Family Kinases; Tamoxifen	2014
Serine deprivation enhances antineoplastic activity of biguanides. Cancer research, 2014, Dec-15, Volume: 74, Issue:24 Topics: Animals; Biguanides; Cell Line, Tumor; Glycolysis; Humans; Metformin; Mice; Neoplasms; Oxidative Phosphorylation; Phenformin; Serine; Xenograft Model Antitumor Assays	2014
Biguanides sensitize leukemia cells to ABT-737-induced apoptosis by inhibiting mitochondrial electron transport. Oncotarget, 2016, Aug-09, Volume: 7, Issue:32 Topics: Apoptosis; Biguanides; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Electron Transport; Humans; Metformin; Mitochondria; Nitrophenols; Phenformin; Piperazines; Rotenone; Sulfonamides; U937 Cells	2016
Molecular features of biguanides required for targeting of mitochondrial respiratory complex I and activation of AMP-kinase. BMC biology, 2016, 08-09, Volume: 14 Topics: Adenylate Kinase; Animals; Biguanides; Cattle; Cell Line, Tumor; Cell Membrane Permeability; Cell Respiration; Electron Transport Complex I; Enzyme Activation; Mice; Mitochondria; Mitochondrial Membranes; Oxygen Consumption; Phenformin; Rats; Rotenone; Solubility	2016
Extreme Basicity of Biguanide Drugs in Aqueous Solutions: Ion Transfer Voltammetry and DFT Calculations. The journal of physical chemistry. A, 2016, Sep-22, Volume: 120, Issue:37 Topics: Biguanides; Hydrogen-Ion Concentration; Metformin; Models, Molecular; Phenformin; Quantum Theory; Solutions; Water	2016
NBR2-GLUT1 axis regulates cancer cell sensitivity to biguanides. Cell cycle (Georgetown, Tex.), 2017, Volume: 16, Issue:3 Topics: Biguanides; Metformin; Phenformin	2017
Pleiotropic Effects of Biguanides on Mitochondrial Reactive Oxygen Species Production. Oxidative medicine and cellular longevity, 2017, Volume: 2017 Topics: Adipose Tissue, Brown; Animals; Biguanides; Glycerolphosphate Dehydrogenase; Hydrogen Peroxide; Hypoglycemic Agents; Membrane Potential, Mitochondrial; Metformin; Mitochondria; Oxidation-Reduction; Phenformin; Rats; Rats, Wistar; Reactive Oxygen Species; Succinic Acid	2017
Effects of Biguanides on Growth and Glycolysis of Bladder and Colon Cancer Cells. Anticancer research, 2018, Volume: 38, Issue:9 Topics: Biguanides; Buformin; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Culture Media; Glucose; Glycolysis; HT29 Cells; Humans; Hydrogen-Ion Concentration; Hypoglycemic Agents; Mitochondria; Phenformin; Proguanil; Urinary Bladder Neoplasms	2018
Electrochemically Modulated Liquid-Liquid Extraction for Sample Enrichment. Analytical chemistry, 2019, 06-04, Volume: 91, Issue:11 Topics: Biguanides; Chromatography, High Pressure Liquid; Electrochemical Techniques; Hydrophobic and Hydrophilic Interactions; Liquid-Liquid Extraction; Metformin; Phenformin; Quaternary Ammonium Compounds	2019